• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.6
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• pp.988-994
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• 1997

The demands for robotic and automatic system are continually increasing in manufacturing fields. There have been many studies to monitor and predict the system, but they have mainly focused upon measuring cutting force, and current of motor spindle, and upon using acoustic sensor, etc. In this study, digital image of time series sequence was acquired by taking advantage of optical technique. Mean square error was obtained from it and was available for useful observation data. The parameter was estimated using PAA(parameter adaptation algorithm) from observation data. AR(auto regressive) model was selected for system model and fifth order was decided according to parameter estimation. Uncorrelation test was also carried out to verify convergence of parameter. Through the proceedings, it was found that there was a system stability.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 1999.05a
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• pp.75-80
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• 1999

As current manufacturing processes require high spindle speed and precise machining, increasing accuracy by reducing volumetric errors of the machine itself, particularly thermal errors, is very important. Thermal errors can be estimated by many empirical models, for example, an FEM model, a neural network model, a linear regression model, an engineering judgment model etc. This paper discusses to make a modeling of thermal errors efficiently through backward elimination and fuzzy logic strategy. The model of a thermal error using fuzzy logic strategy overcome limitation of accuracy in the linear regression model or the engineering judgment model. And this model is compared with the engineering judgment model. It is not necessary complex process such like multi-regression analysis of the engineering judgment model. A fuzzy model does not need to know the characteristics of the plant, and the parameters of the model can be mathematically calculated. Like a regression model, this model can be applied to any machine, but it delivers greater accuracy and robustness.

• Korean Journal of Head & Neck Oncology
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• v.32 no.2
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• pp.9-13
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• 2016

Infantile myofibromatosis is a rare benign neoplasm which is usually found in males. Most cases of the infantile myofibromatosis are discovered before the age of two years and about half of cases are found at muscle, tendon, and soft tissue of head-neck region. However, it is especially uncommon that infantile myofibroma occurs at the pre-auricular area. In current case, we report a twenty two months old male patient with $2.5{\times}1.5cm$ sized pre-auricular mass at right side. It was surgically removed and histologically showed broad bundle of plump myoid spindle cells with eosinophilic cytoplasm and weakly positive smooth muscle actin expression in myoid cells. In three months of follow up, there was no recurrence.

• Imaging Science in Dentistry
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• v.49 no.3
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• pp.235-240
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• 2019

Osteosarcoma is the most common primary bone tumor after plasma cell neoplasms. Osteosarcoma has diverse histological features and is characterized by the presence of malignant spindle cells and pluripotent neoplastic mesenchymal cells that produce immature bone, cartilage, and fibrous tissue. Osteosarcoma most frequently develops in the extremities of long bones, but can occur in the jaw in rare cases. The clinical and biological behavior of osteosarcoma of the jaw slightly differs from that of long-bone osteosarcoma. The incidence of jaw osteosarcoma is greater in the third to fourth decades of life, whereas long-bone osteosarcoma mostly occurs in the second decade of life. Osteosarcoma of the jaw has a lower tendency to metastasize and a better prognosis than long-bone osteosarcoma. Radiographically, osteosarcoma can present as a poorly-defined lytic, sclerotic, or mixed-density lesion with periosteal bone reaction response. Multi-detector computed tomography is useful for identifying the extent of bone destruction, as well as soft tissue involvement of the lesion. The current case report presents a fibroblastic osteosarcoma involving the left hemimandible with very unusual radiographic features.

• Journal of Wind Energy
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• v.10 no.4
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• pp.20-27
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• 2019

High-speed shaft coupling in a wind power system transmits power and absorbs variations in length and spindle dislocation between the gearbox and generator. Furthermore, the coupling has an insulation function that prevents electrical corrosion caused by the flow of the generator's current into the gearbox and prevents overload resulting from sudden power failure from being transferred to the gearbox. Its design, functions, and part verification are described in the IEC61400 and GL Guidelines, which specify that the part must have a durability life of 20 years or longer under distance variation and axial misalignment between the gearbox and the generator. This study presents the design of a high-speed coupling through composite stiffness calculation, structural analysis, and comparative analysis of test and theory to identify the characteristics of high-speed coupling for a large-capacity 6 MW wind power generator. A prototype was fabricated by optimizing the manufacturing process for each part based on the design, and the reliability of the fabricated prototype was verified by evaluating the performance of the target quantitative evaluation items.

• International Journal of Ocean System Engineering
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• v.2 no.4
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• pp.209-213
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• 2012

Recently, the fuel using in the diesel engines of marine ships has been changed to a low quality of heavy oil because of the steady increase in the price of oil. Therefore, the wear and corrosion in all parts of the engine such as the cylinder liner, piston crown, and spindle and seat ring of exhaust valves has correspondingly increased. The repair welding of a piston crown is a unique method for prolonging its lifetime from an economic point of view. In this case, filler metals with a high corrosion and wear resistance are mainly being used for repair welding. However, often at a job site on a ship, a piston crown is actually welded with mild filler metals. Therefore, in this study, mild filler metals such as CSF350H, E8000B2, and 435 were welded to SS401 steel as the base metal, and the corrosion properties of the weld metals with and without post weld heat treatment were investigated using some electrochemical methods in a 0.1% $H_2SO_4$ solution. The weld metal welded with CSF350H filler metal exhibited the best corrosion resistance among these filler metals, irrespective of the heat treatment. However, the weld metal zones of the E8000B2 and 435 filler metals exhibited better and worse corrosion resistance with the heat treatment, respectively. As a result, it is suggested that in the case of repair welding with CSF350H and 435 filler metals, no heat treatment is advisable, while heat treatment is desirable if E8000B2filler metal is used with repair welding.

• Transactions on Electrical and Electronic Materials
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• v.12 no.2
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• pp.56-59
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• 2011

The characterization of the chemical mechanical polishing (CMP) process for undensified phophosilicate glass (PSG) film is reported using design of experiments (DOE). DOE has been used by experimenters to understand the relationship between the input variables and responses of interest in a simple and efficient way, and it typically is beneficial for determining the appropriatesize of experiments with multiple process variables and making statistical inferences for the responses of interest. The equipment controllable parameters used to operate the machine consist of the down force of the wafer carrier, pressure on the back side wafer, table and spindle speeds (SS), slurry flow (SF) rate, pad condition, etc. None of these are independent ofeach other and, thus, the interaction between the parameters also needs to be understoodfor improved process characterization in CMP. In this study, we selected the five controllable equipment parameters the most recommendedby process engineers, viz. the down force (DF), back pressure (BP), table speed (TS), SS, and SF, for the characterization of the CMP process with respect to the material removal rate and film uniformity in percentage terms. The polished material is undensified PSG which is widely used for the plananization of multi-layered metal interconnects. By statistical modeling and the analysis of the metrology data acquired from a series of $2^{5-1}$ fractional factorial designs with two center points, we showed that the DF, BP and TS have the greatest effect on both the removal rate and film uniformity, as expected. It is revealed that the film uniformity of the polished PSG film contains two and three-way interactions. Therefore, one can easily infer that process control based on a better understanding of the process is the key to success in current semiconductor manufacturing, in which the size of the wafer is approaching 300 mm and is scheduled to continuously increase up to 450 mm in or slightly after 2012.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.9 s.180
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• pp.2159-2166
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• 2000

Recently, high performance machining center requires special type of sealing mechanism that prevent a leakage of oil jet or oil mist lubrication system. Sealing of oil-air mixture plays important r oles to have an enhanced lubrication for performance machining center. Current work emphasizes on investigations of the air jet effect on the protective collar type labyrinth seal. To improve sealing capabilities of conventional labyrinth seals, air jet is injected against the leakage flow. In this study, an adapted model is introduced to improve sealing capability of conventional non-contact type seals. It has a combined geometry of a protective collar type and an air jet type. Both of a numerical analysis by CFD (Computational Fluid Dynamics) and experimental measurements are carried out to verify sealing improvement. The sealing effects of the leakage clearance and the air jet magnitude aic studied in various parameters. Gas or liquid has been used as a working fluid for most of nori-contact types seals including the labyrinth seal. However, it is more reasonable to regard two-phase flows because oil mist or oil jet are used for high performance spindle's lubrication. In this study, working fluid is regarded as two phases that are mixed flow of oil and air phase. Both of turbulence and compressible flow model are also introduced in a CFD analysis to represent an isentropic process. Estimation of non-leaking property is determined by amount of pressure drop in the leakage path. Results of pressure drop in the experiment match reasonably to those of the simulation by introducing a flow coefficient. Effect of the sealing improvement is explained as decreasing of leakage clearance by air jetting. Thus, sealing effect is improved by amount of air jetting even though clearance becomes larger

• BMB Reports
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• v.48 no.7
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• pp.413-418
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• 2015

DEPDC1 is a recently identified novel tumor-related gene that is upregulated in several types of cancer and contributes to tumorigenesis. In this study, we have investigated the expression pattern and functional implications of DEPDC1 during cell cycle progression. Expression studies using synchronized cells demonstrated that DEPDC1 is highly expressed in the mitotic phase of the cell cycle. Immunofluorescence assays showed that DEPDC1 is predominantly localized in the nucleus during interphase and is redistributed into the whole cell upon nuclear membrane breakdown in metaphase. Subsequently, siRNA-mediated knockdown of DEPDC1 caused a significant mitotic arrest. Moreover, knockdown of DEPDC1 resulted in remarkable mitotic defects such as abnormal multiple nuclei and multipolar spindle structures accompanied by the upregulation of the A20 gene as well as several cell cycle-related genes such as CCNB1 and CCNB2. Taken together, our current observations strongly suggest that this novel cancerous gene, DEPDC1, plays a pivotal role in the regulation of proper mitotic progression. [BMB Reports 2015; 48(7): 413-418]

• Current Optics and Photonics
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• v.1 no.4
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• pp.412-420
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• 2017

Multinucleated bone resorptive osteoclasts differentiate from bone marrow-derived monocyte/macrophage precursor cells. During osteoclast differentiation, mononuclear pre-osteoclasts change their morphology and biochemical characteristics. In this study, Raman spectroscopy with multivariate techniques such as Principal Component Analysis (PCA) and Linear Discriminant Analysis (LDA) were used to extract biochemical information related to various cellular events during osteoclastogenesis. This technique allowed for label-free and noninvasive monitoring of differentiating cells, and clearly discriminated four different time points during osteoclast differentiation. The Raman band intensity showed significant time-dependent changes that increased up to day 4. The results of Raman spectroscopy agreed with results from atomic force microscopy (AFM) and tartrate-resistant acid phosphatase (TRAP) staining, a conventional biological assay. Under AFM, normal spindle-like mononuclear pre-osteoclasts became round and smaller at day 2 after treatment with a receptor activator of nuclear $factor-{\kappa}B$ ligand and they formed multinucleated giant cells at day 4. Thus, Raman spectroscopy, in combination with PCA-LDA, may be useful for noninvasive label-free quality assessment of cell status during osteoclast differentiation, enabling more efficient optimization of the bioprocesses.