• Archives of Pharmacal Research
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• 제24권6호
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• pp.590-596
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• 2001

A new extended-spectrum ${\beta}-lactamase$ with an isoelectric point (pl) of 6.2 was detected in Klebsiella pneumoniae Fl 61 that was isolated from a patient with infection. This strain was highly resistant to the third or fourth generation cephalosporins such as cceftazidime ceftriaxone, cefoperzaone, and cefpirome. Analysis of this strain by the double disk diffusion test showed synergies between amoxicillin-clavulanate (AMX-CA) and cefotaxime, and AMX-CA and aztreonam, which suggested that this strain produced a extended-spectrum ${\beta}-lactamase$ (ESBL). Cenetic analysis revealed that the resistance was due to the presence of a 9.4-kb plasmic, designated as pkpl 61, encoding for new ${\beta}-lactamase$ gene (bla). Sequence analysis showed that a new bla gene of pkpl 61 differed from $bla_{TEM-1}$ by three mutations leading to the following amino acid substitutions: $Val_{84}{\rightarrow}lie,{\;}Ala_{184}{\rightarrow}Val,{\;}and{\;}Gly_{238}{\rightarrow}Ser$. These mutations have not been reported previously in the TIM type ${\beta}-lactamases$ produced by clinical strains. The novel ${\beta}-lactamase$ was overexpressed in E. coli and purified by ion exchange chromatography on Q-Sepharose and CM-Sepharose, and then further purified by gel filtration on Sehadex G-200. The catalytic activity of th8 purified ${\beta}-lactamase$ was confirmed by the nitrocefin disk.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제51권10호
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• pp.492-499
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• 2002

This paper presents the method for an estimation of discharge current waveform in short gap discharge by radiated electromagnetic fields. The method of current waveform estimation is to use the one antenna method (single field method) with a measured electric or magnetic field at given field point by a time domain antenna. In order to verify the availability of the estimation theory, the discharge current waveform estimation was performed by one antenna methods using the measured electric fields of Wilson & Ma and compared with experiments. In addition diagnosis technique for power equipments is able to prevent from large accidents by finding signs of tile accidents before they happen. From the results of the estimation of discharge current, we have a possibility for the application of insulation diagnosis technique for power equipments using S$F_6$ gas. From this point of view, this paper simulated discharge progress and partial discharge by using needle-plan electrodes system in S$F_6$, studied the distribution of frequency spectrum of the radiated electromagnetic waves using a biconical antenna and a spectrum analyzer. From the experimental results of this study, according to the consideration of the mutual relation between frequency spectrum of the radiated electromagnetic waves and discharge progress, it was confirmed that detecting Partial discharge and estimating discharge progress in S$F_6$ could be Possible.

• 한국ITS학회 논문지
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• 제14권5호
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• pp.44-51
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• 2015

모바일 데이터의 급속한 성장으로 인해 대용량의 백홀 구축 요구가 대두되었으며, 비용 효율 관점에서 쉽게 적은 비용을 가지고 백홀을 신속하게 구축할 수 있는 기술은 점대점 마이크로웨이브이다. 점대점 마이크로웨이브 링크에서의 공간 다이버시티 방법은, 두 개의 수신 안테나에서 오는 신호를 결합시킴으로 페이딩효과를 상쇄시켜 성능을 향상시키는 것이다. 기존의 신호 결합방법으로는 최대 전력 방법과 최소 왜곡 방법이 제안되었다. 하지만, 선택적 페이딩 채널에서 두 기법 모두가 알고리즘의 강건성 관점에서 성능저하가 보고되었다. 그래서, 본 논문에서 현실적 관점에서 효율적이며 더 성능이 향상된 신호결합 기법을 제안하고, 시뮬레이션을 통해 제안된 방법이 신호의 스펙트럼 관점에서 상당한 성능의 향상이 있음을 보인다.

• Earthquakes and Structures
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• 제3권2호
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• pp.141-168
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• 2012

The Retrofit Yield Spectrum (RYS) is a new spectrum-based device that relates seismic demand of a retrofitted structure with the fundamental design parameters of the retrofit. This is obtained from superposition of Yield Point Spectra with design charts that summarize in pertinent spectrum-compatible coordinates the attributes of a number of alternative retrofit scenarios. Therefore, once the requirements for upgrading a given structure have been determined, the RYS enable direct insight of the sensitivity of the seismic response of the upgraded structure to the preliminary design decisions made while establishing the retrofit plan. By virtue of their spectrum-based origin, RYS are derived with reference to a single mode of structural vibration; a primary objective is to control the contribution of this mode in the retrofit design so as to produce a desirable distribution of damage at the ultimate limit state by removing soft storey formations and engaging the maximum number of structural members in deformation, in response to the input motion. Calculations are performed with reference to the yield-point, where secant stiffness is proportional to the flexural strength of reinforced concrete members. Derivation and use of the Retrofit Yield Spectra (RYS) refers to the seismic demand expressed either in terms of spectral acceleration, spectral displacement or interstory drift, at yield of the first storey. A reinforced concrete building that has been tested in full scale to a sequence of simulated earthquake excitations is used in the paper as a demonstration case study to examine the effectiveness of the proposed methodology.

• 한국해양환경ㆍ에너지학회지
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• 제18권4호
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• pp.254-262
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• 2015

가동 물체형 점흡수식 반구형 파력발전장치의 수면하 형상에 대한 매개변수 연구를 수행하였다. 매개변수로는 반구의 반지름과 흘수를 사용하였고, 각 조건에 따른 반구의 상하운동응답을 분석하여 최적의 반지름과 흘수사이의 관계를 추정하였다. 또한 최대 파력 에너지를 추출하기 위해 PTO 시스템으로 인한 추가 감쇠 계수를 부유체의 방사 감쇠 계수와 동일하게 지정하였다. 부유체의 운동응답 스펙트럼과 추출 파워 스펙트럼을 입사파 스펙트럼 첨두 주파수의 변화에 따라 구하였다. 이를 통해, 가용 파 에너지 추출량의 첨두 주파수가 입사파 스펙트럼의 첨두 주파수보다 약 20% 클 때, 최대 파워 실효치를 갖는 것을 알 수 있었다.

• 한국방사선학회논문지
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• 제17권6호
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• pp.889-896
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• 2023

핵의학과에서 가장 많이 사용되는 ^99mTc를 점선원과 산란팬텀을 이용하여 에너지스펙트럼 변화를 분석하고 변화된 감마선 에너지에 따른 납 앞치마의 차폐효과를 평가하였다. 산란팬텀의 감마선 에너지 스펙트럼은 점선원보다 광전피크 영역은 감소하고 컴프턴 산란영역은 증가하였다. 감마선원 형태 변화에 따른 에너지 영역별 계수치는 점선원의 계수치보다 20 cm 거리에서 최대 66.1 %의 감소율을 보였으며 컴프턴 산란 영역에서는 산란팬텀의의 계수치가 점선원의 계수치보다 최대 40 cm 거리에서 122.2 % 증가하는 결과를 보였다. 감마카메라를 이용한 선원과 산란팬텀의 거리에 따른 차폐율 차이에서 광전피크 영역은 유사한 결과를 보였으나 컴프턴 산란영역에서는 20 cm거리에서 산란팬텀의 차폐율이 점선원의 차폐율보다 29.2% 증가하였으며 거리가 증가함에 따라 차폐율 차이는 감소하였다. 방사선 선량계를 이용한 납 앞치마 차폐율 측정에서 산란팬텀의 차폐율은 최대 15.3 %의 차이를 보였으며 거리가 증가할수록 두 선원의 차폐율 차이는 감소하였다. 산란팬텀의 납 앞치마 차폐율이 점선원보다 높고 선원과 가까운 거리일수록 납 앞치마의 효과는 증가하는 결과로 방사성의약품을 주입한 환자를 직접 대면할 때 납 앞치마의 착용은 방사선피폭 저감화에 도움이 될 것으로 판단된다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2012년도 춘계학술대회 논문집
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• pp.45-54
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• 2012

In order to predict trailing edge noise from a flat plate more effectively and accurately, the prediction algorithm based on semi-analytic model for point pressure spectrum is proposed. The semi-analytic model consists of empirical models for point pressure spectra and theoretical model to determine the boundary layer characteristics needed for the empirical models. The proposed methods are applied to predict the trailing edge noise of the flat plate located in the mean flow of speed 38 m/s, for which the measured data are available. In present study, six empirical models for point pressure spectra are utilized for the predictions of trailing edge noise and their prediction results are compared to the measured data. Through the analysis of these comparisons, it is revealed that the present method based on non-frozen formula using Efimtsov model and Smol'yakov-Tkachenko model can provide more accurate and efficient predictions of trailing edge noise.

• 한국소음진동공학회논문집
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• 제22권6호
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• pp.524-534
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• 2012

In order to predict trailing edge noise from a flat plate more effectively and accurately, the prediction algorithm based on semi-analytic model for point pressure spectrum is proposed. The semi-analytic model consists of empirical models for point pressure spectra and theoretical model to determine the boundary layer characteristics needed for the empirical models. The proposed methods are applied to predict the trailing edge noise of the flat plate located in the mean flow of speed 38 m/s, for which the measured data are available. In present study, six empirical models for point pressure spectra are utilized for the predictions of trailing edge noise and their prediction results are compared to the measured data. Through the analysis of these comparisons, it is revealed that the present method based on non-frozen formula using Efimtsov model and Smol'yakov-Tkachenko model can provide more accurate and efficient predictions of trailing edge noise.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2003년도 추계학술대회 논문집
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• pp.232-236
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• 2003

The anchor is laid on seabed and the main engine is worked to against incident environmental loads in typoon. As the main engine is broken down in the storm, the anchor chain is cutted and the vessel is drifted. Although a ship is moored by two point mooring lines to keep the her position, a ship is crashed into a rock because of typoon and the accident of oil spilling may be occured. In this paper, we studied the position-keeping of a ship which is analyized based on the slow motion maneuvering equations considering wave, current and wind. The direct integration method is employed to estimate wave loads. The current forces are calculated by using mathematical of MMG. The two point mooring forces are quasisatatically evaluated by using the catenary equation. The coefficeints of wind forces are modeled from Isherwood’s emperical data and the variation of wind speed is estimated by wind spectrum. The nonlinear motions of a two point moored ship are simulated considering wave, current, wind load in time domain.

• 한국해양공학회지
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• 제18권3호
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• pp.8-12
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• 2004

The anchor is laid on the seabed, and the main engine is working against incident environmental loads in a typhoon. As the main engine is broken Mum in the storm, the anchor chain is cut and the vessel drifts. Although a ship is moored by two-point mooring lines to maintain her position, it has crashed into a rock because of a typhoon, resulting in a possible accidental oil spillage. In this paper, we studied maintenance of a ship's position, which is analyzed based on the slow motion maneuvering equations considering wave, current, and wind. To estimate wave loads, the direct integration method is employed. The current forces are calculated, using MMG (Mathematical Modeling Group). Th two-point mooring forces are quasi-statistically evaluated, using the catenary equation. Th coefficients of wind forces are modeled from Isherwood's empirical data, and the variation of wind speed is estimated by wind spectrum. The nonlinear motions of a two-point moored ship are simulated, considering wave, current, and wind load, in specific domain of time.