• Archives of Pharmacal Research
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• v.24 no.6
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• pp.590-596
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• 2001

A new extended-spectrum ${\beta}-lactamase$ with an isoelectric point (pl) of 6.2 was detected in Klebsiella pneumoniae Fl 61 that was isolated from a patient with infection. This strain was highly resistant to the third or fourth generation cephalosporins such as cceftazidime ceftriaxone, cefoperzaone, and cefpirome. Analysis of this strain by the double disk diffusion test showed synergies between amoxicillin-clavulanate (AMX-CA) and cefotaxime, and AMX-CA and aztreonam, which suggested that this strain produced a extended-spectrum ${\beta}-lactamase$ (ESBL). Cenetic analysis revealed that the resistance was due to the presence of a 9.4-kb plasmic, designated as pkpl 61, encoding for new ${\beta}-lactamase$ gene (bla). Sequence analysis showed that a new bla gene of pkpl 61 differed from $bla_{TEM-1}$ by three mutations leading to the following amino acid substitutions: $Val_{84}{\rightarrow}lie,{\;}Ala_{184}{\rightarrow}Val,{\;}and{\;}Gly_{238}{\rightarrow}Ser$. These mutations have not been reported previously in the TIM type ${\beta}-lactamases$ produced by clinical strains. The novel ${\beta}-lactamase$ was overexpressed in E. coli and purified by ion exchange chromatography on Q-Sepharose and CM-Sepharose, and then further purified by gel filtration on Sehadex G-200. The catalytic activity of th8 purified ${\beta}-lactamase$ was confirmed by the nitrocefin disk.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.51 no.10
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• pp.492-499
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• 2002

This paper presents the method for an estimation of discharge current waveform in short gap discharge by radiated electromagnetic fields. The method of current waveform estimation is to use the one antenna method (single field method) with a measured electric or magnetic field at given field point by a time domain antenna. In order to verify the availability of the estimation theory, the discharge current waveform estimation was performed by one antenna methods using the measured electric fields of Wilson & Ma and compared with experiments. In addition diagnosis technique for power equipments is able to prevent from large accidents by finding signs of tile accidents before they happen. From the results of the estimation of discharge current, we have a possibility for the application of insulation diagnosis technique for power equipments using S$F_6$ gas. From this point of view, this paper simulated discharge progress and partial discharge by using needle-plan electrodes system in S$F_6$, studied the distribution of frequency spectrum of the radiated electromagnetic waves using a biconical antenna and a spectrum analyzer. From the experimental results of this study, according to the consideration of the mutual relation between frequency spectrum of the radiated electromagnetic waves and discharge progress, it was confirmed that detecting Partial discharge and estimating discharge progress in S$F_6$ could be Possible.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.14 no.5
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• pp.44-51
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• 2015

The deployment of high capacity backhaul is required due to explosive growth in mobile data services. For rapid backhaul deployment, point to point microwave is a much easier and cheaper technology. The space diversity scheme is used in point to point microwave links. The purpose of space diversity is to overcome fading by combining signals from two separate receiver antennas. For signal combining algorithm, maximum power and minimum distortion methods were used and these algorithms were reported not to be good enough for robustness in selective fading. In this paper, a more practically efficient signal combining scheme from the main and diversity branch is proposed and evaluated in selective fading channel. The proposed algorithm has shown significant performance improvement in terms of signal spectrum.

• Earthquakes and Structures
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• v.3 no.2
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• pp.141-168
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• 2012

The Retrofit Yield Spectrum (RYS) is a new spectrum-based device that relates seismic demand of a retrofitted structure with the fundamental design parameters of the retrofit. This is obtained from superposition of Yield Point Spectra with design charts that summarize in pertinent spectrum-compatible coordinates the attributes of a number of alternative retrofit scenarios. Therefore, once the requirements for upgrading a given structure have been determined, the RYS enable direct insight of the sensitivity of the seismic response of the upgraded structure to the preliminary design decisions made while establishing the retrofit plan. By virtue of their spectrum-based origin, RYS are derived with reference to a single mode of structural vibration; a primary objective is to control the contribution of this mode in the retrofit design so as to produce a desirable distribution of damage at the ultimate limit state by removing soft storey formations and engaging the maximum number of structural members in deformation, in response to the input motion. Calculations are performed with reference to the yield-point, where secant stiffness is proportional to the flexural strength of reinforced concrete members. Derivation and use of the Retrofit Yield Spectra (RYS) refers to the seismic demand expressed either in terms of spectral acceleration, spectral displacement or interstory drift, at yield of the first storey. A reinforced concrete building that has been tested in full scale to a sequence of simulated earthquake excitations is used in the paper as a demonstration case study to examine the effectiveness of the proposed methodology.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.4
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• pp.254-262
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• 2015

Parametric study on submerged body shape of an oscillating hemisphere point absorber was conducted to predict the optimal relation between radius and draft of the body. As an additional damping due to power takeoff system, the optimal damping same as wave radiation damping was applied to the PTO system to produce the maximum wave power. Body response spectrum and power spectrum were obtained for various peak frequencies on wave spectra. It was found that the maximum power can be generated when the peak frequency of available wave power was 20% greater than that of wave spectrum.

• Journal of the Korean Society of Radiology
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• v.17 no.6
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• pp.889-896
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• 2023

Changes in the energy spectrum were analyzed using ^99mTc as a point source and a scattering phantom, and the shielding effect of the lead apron according to the changed gamma ray energy was evaluated. In the gamma ray energy spectrum of the scattering phantom, the photo peak area decreased and the compton scattering area increased compared to the point source. The coefficients for each energy range according to the change in the shape of the gamma ray source showed a reduction rate of up to 66.1 % at a distance of 20 cm compared to the coefficient of the point source, and in the compton scattering area, the coefficient of the scattering phantom was 122.2 % at a distance of up to 40 cm compared to the coefficient of the point source. In the difference in shielding rate according to the distance between the source and the scattering phantom using a gamma camera, the photo peak area showed similar results, but in the Compton scattering area, the shielding rate of the scattering phantom at a distance of 20 cm increased by 29.2 % compared to the shielding rate of the point source. As the distance increased, the difference in shielding rate decreased. In measuring the shielding rate of the lead apron using a radiation dosimeter, the difference in the shielding rate of the scattering phantom was up to 15.3 %, and as the distance increased, the difference in the shielding rate between the two sources decreased. The shielding rate of the lead apron of the scattering phantom is higher than that of the point source, and the effectiveness of the lead apron increases as the distance to the source increases. As a result, wearing a lead apron when directly confronting a patient who has injected radioactive pharmaceuticals is expected to be helpful in reducing radiation exposure.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2012.04a
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• pp.45-54
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• 2012

In order to predict trailing edge noise from a flat plate more effectively and accurately, the prediction algorithm based on semi-analytic model for point pressure spectrum is proposed. The semi-analytic model consists of empirical models for point pressure spectra and theoretical model to determine the boundary layer characteristics needed for the empirical models. The proposed methods are applied to predict the trailing edge noise of the flat plate located in the mean flow of speed 38 m/s, for which the measured data are available. In present study, six empirical models for point pressure spectra are utilized for the predictions of trailing edge noise and their prediction results are compared to the measured data. Through the analysis of these comparisons, it is revealed that the present method based on non-frozen formula using Efimtsov model and Smol'yakov-Tkachenko model can provide more accurate and efficient predictions of trailing edge noise.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.22 no.6
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• pp.524-534
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• 2012

In order to predict trailing edge noise from a flat plate more effectively and accurately, the prediction algorithm based on semi-analytic model for point pressure spectrum is proposed. The semi-analytic model consists of empirical models for point pressure spectra and theoretical model to determine the boundary layer characteristics needed for the empirical models. The proposed methods are applied to predict the trailing edge noise of the flat plate located in the mean flow of speed 38 m/s, for which the measured data are available. In present study, six empirical models for point pressure spectra are utilized for the predictions of trailing edge noise and their prediction results are compared to the measured data. Through the analysis of these comparisons, it is revealed that the present method based on non-frozen formula using Efimtsov model and Smol'yakov-Tkachenko model can provide more accurate and efficient predictions of trailing edge noise.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2003.10a
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• pp.232-236
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• 2003

The anchor is laid on seabed and the main engine is worked to against incident environmental loads in typoon. As the main engine is broken down in the storm, the anchor chain is cutted and the vessel is drifted. Although a ship is moored by two point mooring lines to keep the her position, a ship is crashed into a rock because of typoon and the accident of oil spilling may be occured. In this paper, we studied the position-keeping of a ship which is analyized based on the slow motion maneuvering equations considering wave, current and wind. The direct integration method is employed to estimate wave loads. The current forces are calculated by using mathematical of MMG. The two point mooring forces are quasisatatically evaluated by using the catenary equation. The coefficeints of wind forces are modeled from Isherwood’s emperical data and the variation of wind speed is estimated by wind spectrum. The nonlinear motions of a two point moored ship are simulated considering wave, current, wind load in time domain.

• Journal of Ocean Engineering and Technology
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• v.18 no.3
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• pp.8-12
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• 2004

The anchor is laid on the seabed, and the main engine is working against incident environmental loads in a typhoon. As the main engine is broken Mum in the storm, the anchor chain is cut and the vessel drifts. Although a ship is moored by two-point mooring lines to maintain her position, it has crashed into a rock because of a typhoon, resulting in a possible accidental oil spillage. In this paper, we studied maintenance of a ship's position, which is analyzed based on the slow motion maneuvering equations considering wave, current, and wind. To estimate wave loads, the direct integration method is employed. The current forces are calculated, using MMG (Mathematical Modeling Group). Th two-point mooring forces are quasi-statistically evaluated, using the catenary equation. Th coefficients of wind forces are modeled from Isherwood's empirical data, and the variation of wind speed is estimated by wind spectrum. The nonlinear motions of a two-point moored ship are simulated, considering wave, current, and wind load, in specific domain of time.