• Bulletin of the Korean Chemical Society
• /
• 제31권9호
• /
• pp.2692-2694
• /
• 2010

• Journal of Applied Biological Chemistry
• /
• 제50권4호
• /
• pp.301-303
• /
• 2007

• 한국동물학회:학술대회논문집
• /
• 한국동물학회 1995년도 한국생물과학협회 학술발표대회
• /
• pp.72-72
• /
• 1995

No Abstract, See Full Text

• Bulletin of the Korean Chemical Society
• /
• 제35권1호
• /
• pp.297-300
• /
• 2014

• KSBB Journal
• /
• 제11권2호
• /
• pp.193-200
• /
• 1996

DNA를 인식하여 절단하는 제한효소의 발견은 유전자를 연구, 조작할 수 있게 되어 분자생물학 연구에 큰 발전을 가져 왔다. 제한효소의 인식자리는 반 응용액의 산도, 유기용애의 소수성에 따라서 달라질 수 있다. 제한 효소 BamHI의 특이성 변화는 유기용 매의 소수성CLogP)과 산도에 직접적인 관계가 있다. 제한효소 BamHI의 인식자리의 특이성 변화는 산도 7.5에셔 LogP값이 -1.3~-1.35, 8.0에서 -1. 0 03~-2.5, 8.5에서 0.75~-2.5, 8.9에서 -0.32 ~­2 2.5 벙위에셔 각각 나타난다. 통일한 유기용매 혼합 물에서 산도가 알카리 일수록 낮은 유기용매 놓도에 서 특이성의 변화가 나타난다. DMSO용액에서 Bam H HI의 특이성 변화는 산도가 7.5일때 20% 농도에서 나타나지만 산도가 8.9일때는 4%에서 나타난다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권17호
• /
• pp.7241-7244
• /
• 2014

Background: To determine the accuracy of preoperative urinary symptoms, urinalysis, computed tomography (CT) and cystoscopic findings for the diagnosis of urinary bladder invasion in patients with colorectal cancer. Materials and Methods: Records of patients with colorectal cancer and a suspicion of bladder invasion, who underwent tumor resection with partial or total cystectomy between 2002 and 2013 at the Faculty of Medicine Siriraj Hospital, were reviewed. Correlations between preoperative urinary symptoms, urinalysis, cystoscopic finding, CT imaging and final pathological reports were analyzed. Results: This study included 90 eligible cases (71% male). The most common site of primary colorectal cancer was the sigmoid colon (44%), followed by the rectum (33%). Final pathological reports showed definite bladder invasion in 53 cases (59%). Significant features for predicting definite tumor invasion were gross hematuria (OR 13.6, sensitivity 39%, specificity 73%), and visible tumor during cystoscopy (OR 5.33, sensitivity 50%, specificity 84%). Predictive signs in CT imaging were gross tumor invasion (OR 7.07, sensitivity 89%, specificity 46%), abnormal enhancing mass at bladder wall (OR 4.09, sensitivity 68%, specificity 66%), irregular bladder mucosa (OR 3.53, sensitivity 70%, specificity 60% ), and loss of perivesical fat plane (OR 3.17, sensitivity 81%, specificity 43%). However, urinary analysis and other urinary tract symptoms were poor predictors of bladder involvement. Conclusions: The present study demonstrated that the most relevant preoperative predictors of definite bladder invasion in patients with colorectal cancer are gross hematuria, a visible tumor during cystoscopy, and abnormal CT findings.

• Journal of Korean Neurosurgical Society
• /
• 제52권5호
• /
• pp.472-475
• /
• 2012

Objective : The aim of this study is to establish the value of hand elevation test as a reproducible provocative test for the diagnosis of carpal tunnel syndrome (CTS). Methods : We had a prospective study of 45 hands of 38 patients diagnosed with CTS between April 2005 and February 2009. The diagnosis of CTS was based on the American Academy of Neurology clinical diagnostic criteria. Experimental and control group patients underwent Tinel's test, Phalen's test, carpal compression test and hand elevation test as provocative tests for CTS. Results : We used chi-square analysis to compare Tinel's test and Phalen's test, carpal compression test with hand elevation test. The sensitivity and specificity of the hand elevation test is 86.7% and 88.9% each. Tinel's test had 82.2% sensitivity and 88.9% specificity. Phalen's test had 84.4% sensitivity and 86.7% specificity. Carpal compression test had 84.4% sensitivity 82.2% specificity. Comparisons of sensitivity and specificity between hand elevation test and Tinel's test, Phalen's test, and carpal compression test had no statistically significant differences. To compare the diagnostic accuracies of four tests, the area under the non-parametric receiver operating character curve was applied. Conclusion : The hand elevation test has higher sensitivity and specificity than Tinel's test, Phalen's test, and carpal compression test. Chi-square statistical analysis confirms the hand elevation test is not ineffective campared with Tinel's test, Phalen's test, and carpal compression test.

• Journal of Preventive Medicine and Public Health
• /
• 제40권4호
• /
• pp.297-304
• /
• 2007

Objectives : We investigated the validity of the dipstick method (Mossman Associates Inc. USA) and the expired CO method to distinguish between smokers and non-smokers. We also elucidated the related factors of the two methods. Methods : This study included 244 smokers and 50 ex-smokers, recruited from smoking cessation clinics at 4 local public health centers, who had quit for over 4 weeks. We calculated the sensitivity, specificity and Kappa coefficient of each method for validity. We obtained ROC curve, predictive value and agreement to determine the cutoff of expired air CO method. Finally, we elucidated the related factors and compared their effect powers using the standardized regression coefficient. Results : The dipstick method showed a sensitivity of 92.6%, specificity of 96.0% and Kappa coefficient of 0.79. The best cutoff value to distinguish smokers was 5-6ppm. At 5 ppm, the expired CO method showed a sensitivity of 94.3%, specificity of 82.0% and Kappa coefficient of 0.73. And at 6 ppm, sensitivity, specificity and Kappa coefficient were 88.5%, 86.0% and 0.64, respectively. Therefore, the dipstick method had higher sensitivity and specificity than the expired CO method. The dipstick and expired CO methods were significantly increased with increasing smoking amount. With longer time since the last smoking, expired CO showed a rapid decrease after 4 hours, whereas the dipstick method showed relatively stable levels for more than 4 hours. Conclusions : The dipstick and expired CO methods were both good indicators for assessing smoking status. However, the former showed higher sensitivity and specificity and stable levels over longer hours after smoking, compared to the expired CO method.

• 통상정보연구
• /
• 제19권1호
• /
• pp.235-256
• /
• 2017

본 연구는 국제합작투자 파트너 기업 간 신뢰와 자산특이성이 합작투자기업의 성과에 미치는 영향을 비선형적 모형을 중심으로 분석하였다. 기존문헌에서는 신뢰 및 자산특이성과 합작투자성과의 관계를 선형적으로 가정했다면, 본 연구에서는 사회적 자본이론과 거래비용이론을 근거로 신뢰 및 자산특이성과 합작성과의 관계가 비선형적 관계를 이룰 것이라는 가설을 설정하고 실증적으로 분석하였다. 한국기업과 외국기업 간에 형성된 한국 내 합작투자 74개의 제조기업을 연구대상으로 설문조사를 실시하여 실증 분석한 결과, 신뢰와 합작투자성과의 관계는 역U자형의 관계를, 자산특이성과 합작투자성과의 관계는 U자형의 관계를 보이는 것으로 나타났다. 이는 국제합작투자 파트너 기업 간의 지나친 신뢰가 파트너간의 적절한 통제력을 상실하지 않도록 신뢰의 적정한 수준을 조절하고 유지해야 하며, 자산특이성으로 인해 발생되는 비용을 최소화하여 긍정적인 효과로 전환하기 위해서는 합작투자기업의 파트너사의 기회주의적 행위에 관한 통제와 모니터링 시스템의 운영과 더불어 새로운 역량을 지속적으로 개발할 수 있는 조직의 유연성과 혁신성을 잃지 않도록 해야 함을 시사한다.

• 유통과학연구
• /
• 제12권10호
• /
• pp.85-97
• /
• 2014

Purpose - This study aims to clarify through which process asset specificity and supplier development project (SDP) affect performance. Cooperation, partnership, the level of information exchange, and the importance of information sharing are considered significant variables as mediators related to the process. Finally, the performance formation model of the supply chain through asset specificity and supplier development project would be suggested as being a result of this study. Research design, data, and methodology - Data collection was as follows: questionnaires were distributed to 250 companies that have business ties with H Company. The empirical study to test our hypothesis was based on statistical analysis (using SPSS 19.0 and AMOS 19.0). The hypothesis of this paper is that the asset specificity and supplier development project variables have positive effects on the following variables: mediators such as cooperation and partnership (reliability and dependence); and the cooperation and partnership variables have a positive effect on the following variables: level of information sharing, the importance of information sharing, and level of information sharing; the importance of information sharing has a positive effect on supply chain performance. We tested our hypothesized model utilizing path analysis with latent variables. Results - First, it was found that asset specificity has significant positive effects on cooperation (H1), reliability (H2), and dependability (H3). Second, it was proved that the level of comprehension on the purpose of SDP has positive effects significantly on cooperation (H4), reliability (H5), and dependability (H6). Third, the hypotheses related to cooperation were all significantly accepted. The relationships of cooperation with the level (H7) and importance (H8) of information sharing were significant. Fourth, the hypotheses related to reliability were all significantly accepted. The relationships of reliability with the level (H9) and importance (H10) of information sharing were significant. In terms of dependability, however, the hypotheses were partially accepted. The effect of dependability was significant on the importance of information sharing (H12), but insignificant on the level of information sharing (H11). Finally, the causal relationships from the level of information sharing to SCM performance (H13) and from the importance of information sharing to SCM performance (H14) were both significantly accepted. Conclusion - First, with rapid changes in the business environment, enterprises should acquire the right information to properly implement SCM. For successful SCM, firms should understand the supplier development project. Second, asset specificity and the level of comprehension on SDP have significant effects both on cooperation and partnership (reliability and dependability). Third, mediators such as cooperation, reliability, and dependability significantly affect the level and importance of information sharing. Fourth, the level and importance of information sharing have significant impacts on SCM performance. This paper makes a meaningful contribution to further the understanding of how SDP affects SCM performance. Finally, successful SCM performance is achieved by information sharing through a collaborative environment and partnership (confidence & dependence) rather than by investing only in setting up an information system.