• Archives of Pharmacal Research
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• 제25권6호
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• pp.725-746
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• 2002

The demand for new alternative "low calorie" sweeteners for dietetic and diabetic purposes has increased worldwide. Although the currently developed and commercially used highly sweet sucrose substitutes are mostly synthetic compounds, the search for such compounds from natural sources is continuing. As of mid-2002, over 100 plant-derived sweet compounds of 20 major structural types had been reported, and were isolated from more than 25 different families of green plants. Several of these highly sweet natural products are marketed as sweeteners or flavoring agents in some countries as pure compounds, compound mixtures, or refined extracts. These highly sweet natural substances are reviewed herein.

• Corrosion Science and Technology
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• 제4권6호
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• pp.231-235
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• 2005

The inhibitive effect of extracts of tamarind seeds and jackfruit seeds, curry leaves and henna leaves on corrosion of mild steel in 1M HCl solution have been studied by weight loss, potentiodynamic polarization and impedance measurements. Results obtained from the electrochemical techniques were in good agreement with weight loss results. From the weight loss data, the values of surface coverage ($\Theta$) and corrosion rate were calculated. The inhibition efficiency (IE) increased with increasing inhibitor concentration in 1M HCl solution. In all the cases the adsorption of the natural product extracts on the mild steel surface from 1M HCl follows the Langmuir adsorption isotherm relationship. Potentiodynamic polarization studies reveal the fact that all the four natural product extracts act as mixed type inhibitors. The decrease in the inhibition efficiency follows the order: Extracts of jackfruit seed>henna leaves>curry leaves>tamarind seed.

• Journal of Dairy Science and Biotechnology
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• 제16권2호
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• pp.106-118
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• 1998

유청은 치즈제조시 부산물로 얻어지는 천연물이며, 새로운 기술발전에 따라 유청단백질의 농축물과 유청분획물들이 여러모로 이용 가능하게 되었고, 또한 여러 종류의 식품의 원료로 제공하게 되었다. 농축 유청단백질은 겔화, 유화성, 휩핑, 수분결합성, 지방대체성 등의 다양한 기능성을 함유하고 있다. 유청의 새로운 분획물인 알파락트알부민, 락토페린, 락토페록시다아제, 펩타이드 등은 이들의 생활성이나 건강향상성때문에 전세계적으로 관심이 높다. 이들 분획물에서 천연 항생물질, 천연 보존료 및 면역 향상 물질 등으로 새롭게 사용이 가능한 것으로 발견되었다. 기능성 식품산업의 성장에 힘입어 증가 추세에 있는 많은 제조업자들이 새로운 제품개발을 성공적으로 하는데 유청의 영양적, 기능적 조건들이 유리하다. 미국은 유청생산이 전세계에서 가장 큰 유일한 생산국이고 또한 수출국이다. 1997년에는 백만톤 이상의 유청제품들이 미국에서 제조되었다.

• 약학회지
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• 제40권5호
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• pp.574-581
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• 1996

The study was initiated to elucidate the protective mechanism by examining in vivo effect of some marine natural products, Styela plicata, Ecklonia stolonifera and Pachymeniopsis elliptica on acetaminophen-induced lipid peroxidation. The methanol extract of S. plicata prevented acetaminophen (800mg/kg, i.p.)-induced hepatotoxicity in rats as evidenced by the decreased formation of lipid peroxide. But the methanol extracts of E. stolonifera and P. elliptica were not affected on the formation of lipid peroxidation. The activities of cytochrome P-450, animopyrine N-demethylase and aniline hydroxylase were not changed by the treatment with S. plicata in comparison with acetaminophen-teated group. In acetaminophen-treated control rats, the glutathione S-transferase activity was decreased markably. However. in S. plicata pretreated group, the effect caused by acetaminophen was markably reduced. A-cetaminophen decreased the level of hepatic, glutathione, which was restored to same degree by S. plicata pretreatment. And activity of ${\gamma}$-glutamylcystein synthetase was not changed by S. plicata pretreatment, but the activity of glutathione reductase was increased significantly.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.427-436
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• 2012

Targeted therapy has been a very promising strategy of drug development research. Many molecular mechanims of diseases have been known to be regulated by abundance of proteins, such as receptors and hormones. Chemoprevention for treatment and prevention of diseases are continuously developed. Pre-clinical and clinical studies in chemoprevention field yielded many valuable data in preventing the onset of disease and suppressing the progress of their growth, making chemoprevention a challenging and a very rational strategy in future researches. Natural products being rich of flavonoids are those fruits belong to the genus citrus. Ethanolic extract of Citrus reticulata and Citrus aurantiifolia peels showed anticarcinogenic, antiproliferative, co-chemotherapeutic and estrogenic effects. Several examples of citrus flavonoids that are potential as chemotherapeutic agents are tangeretin, nobiletin, hesperetin, hesperidin, naringenin, and naringin. Those flavonoids have been shown to possess inhibition activity on certain cancer cells' growth through various mechanisms. Moreover, citrus flavonoids also perform promising effect in combination with several chemotherapeutic agents against the growth of cancer cells. Some mechanisms involved in those activities are through cell cycle modulation, antiangiogenic effect, and apoptosis induction.Previous studies showed that tangeretin suppressed the growth of T47D breast cancer cells by inhibiting ERK phosphorylation. While in combination with tamoxifen, doxorubicin, and 5-FU, respectively, it was proven to be synergist on several cancer cells. Hesperidin and naringenin increased cytotoxicitity of doxorubicin on MCF-7 cells and HeLa cells. Besides, citrus flavonoids also performed estrogenic effect in vivo. One example is hesperidin having the ability to decrease the concentration of serum and hepatic lipid and reduce osteoporosis of ovariectomized rats. Those studies showed the great potential of citrus fruits as natural product to be developed as not only the source of co-chemotherapeutic agents, but also phyto-estrogens. Therefore, further study needs to be conducted to explore the potential of citrus fruits in overcoming cancer.

• Design & Manufacturing
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• 제6권2호
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• pp.70-73
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• 2012

Drill process is usually used to manufacture a industry about processing, Therefore, the burr problem is very significant, The burrs took place when drill process. And then, sometimes, the burrs are often caused of some problems during automatic such as no good quality products and having good surface roughness products. And also, this paper had some experiments using magnesium. Specially, the magnesium is one of the non-ferromagnetic materials. Magnesium has attracted a lot of interest for using the industry. They offer a possible alternative to steel and aluminum in automotive and aero industries to satisfy the lightweight requirement. also, magnesium has good specific strength and absorbs vibration in occurring working process. So, it has good quality of product processing. And then, it is one of the lightest materials being used to electronic product's cases and automotive because of lightweight and miniaturization. But this material has not widely used all of the industry due to its natural property. If the magnesium is contacted water, it will cause the exploration. But, nowadays many of people study magnesium to safe their experiment and to widely use this industry.

• 한국금형공학회:학술대회논문집
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• 한국금형공학회 2008년도 하계 학술대회
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• pp.51-54
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• 2008

Drill process is usually used to manufacture a industry about processing, Therefore, the burr problem is very significant, The burrs took place when drill process. And then, sometimes, the burrs are often caused of some problems during automatic such as no good quality products and having good surface roughness products. And also, this paper had some experiments using magnesium. Specially, the magnesium is one of the non-ferromagnetic materials. Magnesium has attracted a lot of interest for using the industry. They offer a possible alternative to steel and aluminum in automotive and aero industries to satisfy the lightweight requirement. also, magnesium has good specific strength and absorbs vibration in occurring working process. So, it has good quality of product processing. And then, it is one of the lightest materials being used to electronic product's cases and automotive because of lightweight and miniaturization. But this material has not widely used all of the industry due to its natural property. If the magnesium is contacted water, it will cause the exploration. But, nowadays many of people study magnesium to safe their experiment and to widely use this industry.

• 한국의상디자인학회지
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• 제23권2호
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• pp.165-176
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• 2021

To solve environmental problems, research and efforts are required to reduce leather waste that is generated in large quantities during the leather manufacturing process. Leatherboard is a plate-like material that is made by crushing leather waste, such as trimming or shaving scraps and mixing fibers, pulp, rubber, and adhesives. The aim of this study is to provide basic data on the localization of leatherboard manufacturing technology for outsoles, which are increasingly in demand due to their excellent performance and price competitiveness. Interviews with experts and related organizations were conducted to investigate the related global technology trends. Also, the performance of three products that can be used as reference materials were evaluated and compared. As part of the research and efforts to reduce the amount of leather waste generated, high-performance materials using leather waste were developed and commercialized by major western companies. In Korea, various efforts have been made since 2000, and some companies have produced leatherboard for interior uses. However, the amount of waste recycled relative to that generated is not large due to the limited demand. Natural leather soles perform better than leatherboard soles in all evaluation aspects. In the case of leatherboard, performance varied by manufacturer. German products showed flexibility resistance and dimensional stability, thereby meeting performance requirements. However, abrasion resistance and cleavage resistance were slightly below the required performance standards, and research and development is needed to improve performance in those areas. Currently, it is impossible to evaluate the performance of domestic products due to underdevelopment. However, if the development of process technology continues based on the performance evaluation results of the best leatherboard in the shoe industry, materials for outsoles will be able to be produced domestically with prices competitiveness while realizing natural leather materials performance to some extent.

• 식물병연구
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• 제18권1호
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• pp.40-44
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• 2012

자두 검은점무늬병에 걸린 식물체로부터 순수분리된 X. arboricola pv. pruni 균을 NA배지에서 배양한 후 국내재배 핵과류에 분무접종한 결과 자두, 매실, 살구에 있어서는 과실에 뚜렷한 병원성을 나타내었으나 복숭아 과실은 저항성을 나타내었다. 특히 매실과 살구에서는 극심한 초기 과민성반응이 나타났는데 과실의 50% 정도가 생장 정지되어 낙과되는 현상을 보였으며 병반의 크기는 자두와는 달리 크게 진행되지 않고 많은 점무늬를 형성하는 병반형태를 나타내었고 복숭아에서는 과실병징이 나타나지 않았다. 접종된 여름철 신초가지에서 자두 포모사품종에서는 도관부까지 궤양조직이 형성되었으나 살구 그리고 매실에서는 체관부일부에서만 궤양조직이 형성되어 분리된 병원균은 자두 포모사품종에 특이적인 감염조직을 형성함을 알 수 있었다.

• 한국방재학회:학술대회논문집
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• 한국방재학회 2007년도 정기총회 및 학술발표대회
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• pp.223-230
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• 2007

Nowaday, for the promotion of producing forest trees, production of excellent timbers, and build-up of public forest area, it is on the increase of the thinning-forest for artificial forest, natural forest, eco-friendly forest, and the forest for development and improvement of forest resources nationwide. Even though the thinning-forest is applied around 180,000ha every year, the quantity of collected/used products is only 18,000ha $(240,000m^3)$ which is 10% of the whole thinning-forest area. Meanwhile, some reports represent that the left products after thinning-forest might increase the severity of forest fire and the waste of resources. Therefore, this study focused on the analysis of correlation between the accumulated products after thinning-forest and forest fire, and providing a preparation plan for the forest fire.