• Archives of Pharmacal Research
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• v.25 no.6
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• pp.725-746
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• 2002

The demand for new alternative "low calorie" sweeteners for dietetic and diabetic purposes has increased worldwide. Although the currently developed and commercially used highly sweet sucrose substitutes are mostly synthetic compounds, the search for such compounds from natural sources is continuing. As of mid-2002, over 100 plant-derived sweet compounds of 20 major structural types had been reported, and were isolated from more than 25 different families of green plants. Several of these highly sweet natural products are marketed as sweeteners or flavoring agents in some countries as pure compounds, compound mixtures, or refined extracts. These highly sweet natural substances are reviewed herein.

• Corrosion Science and Technology
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• v.4 no.6
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• pp.231-235
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• 2005

The inhibitive effect of extracts of tamarind seeds and jackfruit seeds, curry leaves and henna leaves on corrosion of mild steel in 1M HCl solution have been studied by weight loss, potentiodynamic polarization and impedance measurements. Results obtained from the electrochemical techniques were in good agreement with weight loss results. From the weight loss data, the values of surface coverage ($\Theta$) and corrosion rate were calculated. The inhibition efficiency (IE) increased with increasing inhibitor concentration in 1M HCl solution. In all the cases the adsorption of the natural product extracts on the mild steel surface from 1M HCl follows the Langmuir adsorption isotherm relationship. Potentiodynamic polarization studies reveal the fact that all the four natural product extracts act as mixed type inhibitors. The decrease in the inhibition efficiency follows the order: Extracts of jackfruit seed>henna leaves>curry leaves>tamarind seed.

• Journal of Dairy Science and Biotechnology
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• v.16 no.2
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• pp.106-118
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• 1998

Whey is a natural product obtained during cheese production. With the advent of new technology, whey protein concentrates and whey fractions have become readily available and versatile food ingredients. Whey protein concentrates are highly functional ingredients that have gelling, emulsifying, whipping, water-binding and fat-replacement properties. New fractions derived from whey (such as alpha-lactalbumin, lactoferrin, lactoperoxidase and peptides) attract considerable interest worldwide because of their bioactive or health-enhancing properties. Some of these fractions also find new uses as natural antibiotic, natural preservative and immunity-enhancing agents. With the growth of the functional foods industry sector, an increasing number of manufacturers take advantage of whey's nutritional and functional benefits to develop successful new products. The United States is the world's largest single producer and exporter of whey products. In 1997, more than 1 million metric tons of whey products were manufacturers in the U.S.

• YAKHAK HOEJI
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• v.40 no.5
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• pp.574-581
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• 1996

The study was initiated to elucidate the protective mechanism by examining in vivo effect of some marine natural products, Styela plicata, Ecklonia stolonifera and Pachymeniopsis elliptica on acetaminophen-induced lipid peroxidation. The methanol extract of S. plicata prevented acetaminophen (800mg/kg, i.p.)-induced hepatotoxicity in rats as evidenced by the decreased formation of lipid peroxide. But the methanol extracts of E. stolonifera and P. elliptica were not affected on the formation of lipid peroxidation. The activities of cytochrome P-450, animopyrine N-demethylase and aniline hydroxylase were not changed by the treatment with S. plicata in comparison with acetaminophen-teated group. In acetaminophen-treated control rats, the glutathione S-transferase activity was decreased markably. However. in S. plicata pretreated group, the effect caused by acetaminophen was markably reduced. A-cetaminophen decreased the level of hepatic, glutathione, which was restored to same degree by S. plicata pretreatment. And activity of ${\gamma}$-glutamylcystein synthetase was not changed by S. plicata pretreatment, but the activity of glutathione reductase was increased significantly.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.427-436
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• 2012

Targeted therapy has been a very promising strategy of drug development research. Many molecular mechanims of diseases have been known to be regulated by abundance of proteins, such as receptors and hormones. Chemoprevention for treatment and prevention of diseases are continuously developed. Pre-clinical and clinical studies in chemoprevention field yielded many valuable data in preventing the onset of disease and suppressing the progress of their growth, making chemoprevention a challenging and a very rational strategy in future researches. Natural products being rich of flavonoids are those fruits belong to the genus citrus. Ethanolic extract of Citrus reticulata and Citrus aurantiifolia peels showed anticarcinogenic, antiproliferative, co-chemotherapeutic and estrogenic effects. Several examples of citrus flavonoids that are potential as chemotherapeutic agents are tangeretin, nobiletin, hesperetin, hesperidin, naringenin, and naringin. Those flavonoids have been shown to possess inhibition activity on certain cancer cells' growth through various mechanisms. Moreover, citrus flavonoids also perform promising effect in combination with several chemotherapeutic agents against the growth of cancer cells. Some mechanisms involved in those activities are through cell cycle modulation, antiangiogenic effect, and apoptosis induction.Previous studies showed that tangeretin suppressed the growth of T47D breast cancer cells by inhibiting ERK phosphorylation. While in combination with tamoxifen, doxorubicin, and 5-FU, respectively, it was proven to be synergist on several cancer cells. Hesperidin and naringenin increased cytotoxicitity of doxorubicin on MCF-7 cells and HeLa cells. Besides, citrus flavonoids also performed estrogenic effect in vivo. One example is hesperidin having the ability to decrease the concentration of serum and hepatic lipid and reduce osteoporosis of ovariectomized rats. Those studies showed the great potential of citrus fruits as natural product to be developed as not only the source of co-chemotherapeutic agents, but also phyto-estrogens. Therefore, further study needs to be conducted to explore the potential of citrus fruits in overcoming cancer.

• Design & Manufacturing
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• v.6 no.2
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• pp.70-73
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• 2012

Drill process is usually used to manufacture a industry about processing, Therefore, the burr problem is very significant, The burrs took place when drill process. And then, sometimes, the burrs are often caused of some problems during automatic such as no good quality products and having good surface roughness products. And also, this paper had some experiments using magnesium. Specially, the magnesium is one of the non-ferromagnetic materials. Magnesium has attracted a lot of interest for using the industry. They offer a possible alternative to steel and aluminum in automotive and aero industries to satisfy the lightweight requirement. also, magnesium has good specific strength and absorbs vibration in occurring working process. So, it has good quality of product processing. And then, it is one of the lightest materials being used to electronic product's cases and automotive because of lightweight and miniaturization. But this material has not widely used all of the industry due to its natural property. If the magnesium is contacted water, it will cause the exploration. But, nowadays many of people study magnesium to safe their experiment and to widely use this industry.

• 한국금형공학회:학술대회논문집
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• 2008.06a
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• pp.51-54
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• 2008

Drill process is usually used to manufacture a industry about processing, Therefore, the burr problem is very significant, The burrs took place when drill process. And then, sometimes, the burrs are often caused of some problems during automatic such as no good quality products and having good surface roughness products. And also, this paper had some experiments using magnesium. Specially, the magnesium is one of the non-ferromagnetic materials. Magnesium has attracted a lot of interest for using the industry. They offer a possible alternative to steel and aluminum in automotive and aero industries to satisfy the lightweight requirement. also, magnesium has good specific strength and absorbs vibration in occurring working process. So, it has good quality of product processing. And then, it is one of the lightest materials being used to electronic product's cases and automotive because of lightweight and miniaturization. But this material has not widely used all of the industry due to its natural property. If the magnesium is contacted water, it will cause the exploration. But, nowadays many of people study magnesium to safe their experiment and to widely use this industry.

• Journal of the Korea Fashion and Costume Design Association
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• v.23 no.2
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• pp.165-176
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• 2021

To solve environmental problems, research and efforts are required to reduce leather waste that is generated in large quantities during the leather manufacturing process. Leatherboard is a plate-like material that is made by crushing leather waste, such as trimming or shaving scraps and mixing fibers, pulp, rubber, and adhesives. The aim of this study is to provide basic data on the localization of leatherboard manufacturing technology for outsoles, which are increasingly in demand due to their excellent performance and price competitiveness. Interviews with experts and related organizations were conducted to investigate the related global technology trends. Also, the performance of three products that can be used as reference materials were evaluated and compared. As part of the research and efforts to reduce the amount of leather waste generated, high-performance materials using leather waste were developed and commercialized by major western companies. In Korea, various efforts have been made since 2000, and some companies have produced leatherboard for interior uses. However, the amount of waste recycled relative to that generated is not large due to the limited demand. Natural leather soles perform better than leatherboard soles in all evaluation aspects. In the case of leatherboard, performance varied by manufacturer. German products showed flexibility resistance and dimensional stability, thereby meeting performance requirements. However, abrasion resistance and cleavage resistance were slightly below the required performance standards, and research and development is needed to improve performance in those areas. Currently, it is impossible to evaluate the performance of domestic products due to underdevelopment. However, if the development of process technology continues based on the performance evaluation results of the best leatherboard in the shoe industry, materials for outsoles will be able to be produced domestically with prices competitiveness while realizing natural leather materials performance to some extent.

• Research in Plant Disease
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• v.18 no.1
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• pp.40-44
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• 2012

Xanthomonas arboricola pv. pruni is the causal agent of bacterial black spot disease on some stone fruits, e.g. peach, plum and apricot. To evaluate pathogenicity of Xanthomonas arboricola pv. pruni strain from plum, inoculum of the isolated strain was spray inoculated to fruits and leaves of apricot, Japanese apricot and plum. Apricot and Japanese apricot showed severe black spot symptoms on fruits and shot hole symptoms on leaves. In case of apricot, about fifty percent of fruits did not grow and dropped by hypersensitive reaction to spray infection. Plum, cv. Formosa was very susceptible, showing severe black injury lesions on fruits and cankers on leaves and new twigs. On the other hand, plum cv. Daesukjosaeng, was highly resistant. Fruits of several plum cultivars such as Formosa and Chuhee were severely infected at natural infected orchards by X. arboricola pv. pruni. Where as those of Daesukjosaeng, Taeyang, Soldam and Hongrogen were moderately infected.

• 한국방재학회:학술대회논문집
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• 2007.02a
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• pp.223-230
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• 2007

Nowaday, for the promotion of producing forest trees, production of excellent timbers, and build-up of public forest area, it is on the increase of the thinning-forest for artificial forest, natural forest, eco-friendly forest, and the forest for development and improvement of forest resources nationwide. Even though the thinning-forest is applied around 180,000ha every year, the quantity of collected/used products is only 18,000ha $(240,000m^3)$ which is 10% of the whole thinning-forest area. Meanwhile, some reports represent that the left products after thinning-forest might increase the severity of forest fire and the waste of resources. Therefore, this study focused on the analysis of correlation between the accumulated products after thinning-forest and forest fire, and providing a preparation plan for the forest fire.