• Title/Summary/Keyword: some natural products

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Phytochemical constituents from Cacalia karaiensis Nakai

  • Lee, Sung-Ok;Choi, Sang-Zin;Kim, Su-Hak;Yang, Min-Cheol;Chung, Ae-Kyung;Nam, Jung-Hwan;Lee, Kyu-Ha;Lee, Kang-Ro
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.375.1-375.1
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    • 2002
  • As part of a research program on the bioactive terpene constituents of Korean compositae plants. we have investigated Cacalia koraiensis (compositae). collected from Gangwon Province on August 2001. On reviewing the literatures of this species. triterpenes and pyrrolizidine alkaloids were isolated and some pharmacological activities were investigated. This species have been used for tinea and spasmolysis However. chemical constituents of this plant have not been reported. (omitted)

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Phytochemical Constitutents of Siegesbeckia pubesence Makino.

  • Nam, Jung-Hwan;Choi, Sang-Zin;Lee, Sung-Ok;Yang, Min-Cheol;Chung, Ae-Kyung;Lee, Kyu-Ha;Shin, Dae-Hee;Lee, Kang-Ro
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.374.2-374.2
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    • 2002
  • Siegesbeckia pubesence (Cempesitae). a perenial herb, is widely distributed in our country and has been used for rheumaic arthritis, hypertension, malaria. neurasthnia and snake-bite in traditional Chinese medicine. On reviewing the literatures of this plant. diterpenoids and alkaloids were isolated and some pharmacological activities were investigated. As part of our systematic study fer Korean Compositae plants, we have investigated Siegesbeckia pubesence (7kg), cellected from Mt. Odae on Aug. 2001. (omitted)

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Terpene Constituents from Aster spathulifolius

  • Lee, Sung-Ok;Choi, Sang-Zin;Yang, Min-Cheol;Nam, Jung-Hwan;Lee, Kyu-Ha;Lee, Jong-Hwa;Jang, Ki-Uk;Lee, Kang-Ro
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.192.3-193
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    • 2003
  • Aster species has been used in traditional chinese medicine for treatment of a bruies and asthma. On reviewing the literatures of this species, monoterpene glycosides, diterpenoids, triterpene glycosides, cyclic pentapeptides, oligopeptides and flavonoids 1) were isolated and some pharmacological activites were investigated 2). In continuation of our search for bioative components from Korean medicinal plants, we have examined Aster spathulifolius, collected from Jeju island on August 2001. (omitted)

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Antidiabetic Effect Screening of Some Natural Products (천연물의 항 당뇨 효능검색)

  • Kim, Jong-Ho;Kim, Kyoung-Soon;Park, Jeong-Hill;Lee, Bong-Jin;Huh, Hoon;Jeong, Gi-Hwa;Cheong, Chun-Sik;Kim, Bak-Kwang
    • Biomolecules & Therapeutics
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    • v.4 no.3
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    • pp.291-295
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    • 1996
  • For the screening of antidiabetic effect, this study was carried out to some natural products by measurements of glucose level. MeOH and $CH_2Cl_2$ extracts of natural products were investigated for the effect on glucose level of $N_2$-STZ diabeted Rat. Among the natural products, Dioscorea Rhizoma, Trichosanthes Radix, Nelumbis Semem and Lycii Fructus were shown a remarkable antidiabetic effect.

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Biological evaluation of Korean medicinal plants

  • Woo, Won-Sick;Shin, Kuk-Hyun;Kwon, Young-Myung
    • YAKHAK HOEJI
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    • v.16 no.3
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    • pp.121-128
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    • 1972
  • Alcohol extracts of 70 Korean medicinal plants have been tested for their biological activity. Most of the extracts had slight activity only. Some extracts had more pronounced activity. The results are tabulated.

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Identification study of rare and high-priced natural products used for oriental medicine by RAPD analysis (RAPD 분석법을 이용한 산삼, 웅담, 녹용 등의 한약재 판별연구)

  • Cho, Dong-Wuk
    • Korean Journal of Oriental Medicine
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    • v.1 no.1
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    • pp.471-476
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    • 1995
  • Natural products used for oriental medicine often come from various geographical sources, after several different distribution channels. Therefore some form of quality control procedure is required to safeguard naturl products for prescriptions purposes. To achieve this, systematic apprroaches such as morphological examination, microscopic analysis of powdered herbs and chemical analysis can be carried out. However, to ensure absolute criteria for quality assurance of natural products, DNA fingerprinting method such as RAPD(Random amplified polymorphism DNA) analysis can be used for authentication of natural products for authenticatin of natural products. In this study, warious oligonucleotide primers will be synthesized for the detection of RAPD markers and also parameters of affecting PCR(Polymerase Chain Reaction) in the detection of RAPD markers of rare and high-priced natural products will be studied with genomic DNA of chosen samples.

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A survey of the response of Korean medicinal plants on drug metabolism

  • Woo, Won-Sick;Shin, Kuk-Hyun;Kim, In-Chull;Lee, Chung-Kyu
    • Archives of Pharmacal Research
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    • v.1 no.1
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    • pp.13-20
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    • 1978
  • Alcohol extracts of plants widely used in the traditional medicine have been tested to establish if they affect the metabolism of drug in mice. Forteen of the plants tested exhibited prolonging and/or inhibitory effect on hexobarbital sleeping time. Some of them also showed increasing effect on strychnine mortality, whereas piperis retrofracti Fructus reduced the toxicity of strychnine.

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Dopamine $\beta$-Hydroxylase Inhibitory Activity of Chinese Herbal Drugs

  • Sun, Ji-Yeon;Lee, Jee-Hwan;Ki, Chan-Young;Han, Yong-Nam
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.272.2-272.2
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    • 2003
  • Dopamine ${\beta}$-hydroxylase (DBH) synthesizes norepinephrine from dopamine under the presence of ascorbate as a coenzyme. Dopamine is transported into the vesicles of the varicosity, where the synthesis and the storage of norepinephrine take place. Some drugs such as DBH inhibitors, dopaminergic agonists,etc. are known to assist in treating Parkinson's disease. (omitted)

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Deodorizing Responses of the Steam Distillate from Some Medicinal Plants (수종 생약 수증기 증류물의 탈취작용)

  • Shin, Kuk-Hyun;Lee, Eun-Bang;Song, Young-Jin;Kim, Oon-Ja
    • Korean Journal of Pharmacognosy
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    • v.23 no.3
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    • pp.153-157
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    • 1992
  • The deodorizing responses of the steam distillate from some medicinal plants(G-3) on three representative malodors were evaluated by estimating the best estimate threshold(BET) of odor responses. With a single spray of G-3, the BETs of malodors such as ammonia, acetic acid, and ethyl acetate were found to increase 4.11, 32.6 and 13.1 fold, respectively, which indicated G-3 possessed a potent deodorizing activity. The deodorizing potency of G-3 was also demonstrated to be as high as and even higher than those of the commercial deodorizing agents.

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ANTIFUNGAL AND ANTIBACTERIAL ACTIVITIES OF SOME COMPOUNDS FROM MARINE NATURAL PRODUCTS

  • Chinh, Luu-Van;Dien, Pham-Huu;Minh, Chau-Van
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1998.11a
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    • pp.174-174
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    • 1998
  • Twelve different derivatives were synthesised from chitin/chitosan[1, 2, 3]. Their structures have been determined by different physical methods. The bioassay screening on antifungal and antibacterial activities of all these compounds showed that most of them had significant activity and they can inhibite the growth of some fungi and bacterias : E. coli, S. pyogenes, F. oxysporum, P. oryzae, that caused the spoilage of fresh fruits and foods. Furthermore, all of these compounds are non-toxic (LD$\_$50/>50g/kg) and can be applied for food preservation.

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