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뇌졸중 환자의 하지 강직에 대한 음양경락별 전침의 효과 (The Effect of Electroacupuncture by Yin and Yang meridians on Leg Spasticity of Stroke Patients)

  • 박세욱;이민구;이선우;강백규;손지우;박상무;이인;문병순
    • 대한한방내과학회지
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    • 제27권2호
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    • pp.371-378
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    • 2006
  • Objectives : The aim of this study is to review the effects of acupuncture on lower limb spasticity control in stroke patients. Methods: H-reflex/M-response ratio and Modified Ashworth Scale was used for evaluation of spasticity control before acupuncture, within one hours after acupuncture , at twenty-four hours, and four weeks. We divided two groups. One is the yin meridian acupunctured goup and the other is the yang meridian acupunctured group. Results: H/M ratio is declined within 1 or 24 hours after acupuncture for poststroke spasticity patients. The yin meridian acupunctured group is a bit more efficient than the yang meridian acupunctured goup. But there is no meaning in the statistics because of small patient pool. Conclusions: We need more patients group to decide the effect of electro- acupuncture on leg spasticity of stroke patients.

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태양열 이용을 위한 직접접촉식 액-액 열교환기 특성 (Characteristics of Liquid-Liquid Direct Contact Heat Exchanger for a Solar System)

  • 강인석;김종보;강용혁;곽희열
    • 대한기계학회논문집
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    • 제18권12호
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    • pp.3276-3286
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    • 1994
  • In most direct contact liquid-liquid heat exchangers, oil or hydrocarbon with a density less than water is normally used as dispersed working fluid. The main difficulty that arises with this arrangement lies in the control of the interface at the top of the column. When it is connected with a solar collector which uses water as its working fluid, the main difficulties arise from the fact that the water can be frozen during winter time. In order to solve these problems and to demonstrate the technical feasibility of a direct contact liquid-liquid heat exchanger, liquids heavier than water with low freezing temperature has been utilized as dispersed phase liquids in a small laboratory scale model made of pyrex glass. In the present investigation, dimethyl phthalate(C/sub 6/H/sub 4/)COOCH/sub 3/)/sub 2/) and diethyl phthalate (C/sub 6/H/sub 4/(CO/sub 2/C/sub 2/H/sub 5/)/sub 2/) are utilized as heavy dispersed phase working fluids. The results of the present investigation the technical in the utilization of heavier dispersed working liquid in the spray-column liquid-liquid heat exchanger for a solar system. The overall average temperature difference along the column is found to be almost half of the initial temperature difference between the dispersed and the continuous phase. Despite the fact that the two phthalates tested in the experiment differ significantly in some of their physical properties, the volumetric heat transfer coefficients in terms of dispersed fluid superficial velocities were found to be similar for both phthalates tested.

Production of the Rare Ginsenoside Rh2-MIX (20(S)-Rh2, 20(R)-Rh2, Rk2, and Rh3) by Enzymatic Conversion Combined with Acid Treatment and Evaluation of Its Anti-Cancer Activity

  • Song, Bong-Kyu;Kim, Kyeng Min;Choi, Kang-Duk;Im, Wan-Taek
    • Journal of Microbiology and Biotechnology
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    • 제27권7호
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    • pp.1233-1241
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    • 2017
  • The ginsenoside Rh2 has strong anti-cancer, anti-inflammatory, and anti-diabetic effects. However, the application of ginsenoside Rh2 is restricted because of the small amounts found in Korean white and red ginsengs. To enhance the production of ginsenoside Rh2-MIX (comprising 20(S)-Rh2, 20(R)-Rh2, Rk2, and Rh3 as a 10-g unit) with high specificity, yield, and purity, a new combination of enzymatic conversion using the commercial enzyme Viscozyme L followed by acid treatment was developed. Viscozyme L treatment at pH 5.0 and $50^{\circ}C$ was used initially to transform the major ginsenosides Rb1, Rb2, Rc, and Rd into ginsenoside F2, followed by acid-heat treatment using citric acid 2% (w/v) at pH 2.0 and $121^{\circ}C$ for 15 min. Scale-up production in a 10-L jar fermenter, using 60 g of the protopanaxadiol-type ginsenoside mixture from ginseng roots, produced 24 g of ginsenoside Rh2-MIX. Using 2 g of Rh2-MIX, 131 mg of 20(S)-Rh2, 58 mg of 20(R)-Rh2, 47 mg of Rk2, and 26 mg of Rh3 were obtained at over 98% chromatographic purity. Then, the anti-cancer effect of the four purified ginsenosides was investigated on B16F10, MDA-MB-231, and HuH-7 cell lines. As a result, these four rare ginsenosides markedly inhibited the growth of the cancer cell lines. These results suggested that rare ginsenoside Rh2-MIX could be exploited to prepare an anti-cancer supplement in the functional food and pharmaceutical industries.

연소 후 CO2 포집을 위한 흡수제의 재생반응에 의한 성능 해석 (Performance Analysis of Absorbent for Post-combustion CO2 Capture by Regeneration)

  • 길태형;이동호;조성호;이창근;박영성;류호정
    • 한국수소및신에너지학회논문집
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    • 제27권1호
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    • pp.83-94
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    • 2016
  • Performance of absorbent for post-combustion $CO_2$ capture was measured and discussed. Fully saturated fresh absorbent (P2-15F) and absorbents sampled from absorption and regeneration reactor of continuous $CO_2$ capture process, P2-15A, P2-15R, respectively, were used as representative absorbents. Small scale fluidized bed reactor (0.05 m I.D., 0.8 m high) which can measure exhaust gas concentration and weight change simultaneously was used to analyze regeneration characteristics for those absorbents. Exhausted moles of $CO_2$ and $H_2O$ were measured with increasing temperature. $H_2O/CO$ ratio and working capacity were determined and discussed to confirm reason of reactivity decay after continuous operation. Moreover, possibility of side reaction was checked based on the $H_2O/CO_2$ mole ratio. Finally, suitable regeneration temperature range was confirmed based on the trend of working capacity with temperature.

Genetic diversity analysis of Thai indigenous pig population using microsatellite markers

  • Charoensook, Rangsun;Gatphayak, Kesinee;Brenig, Bertram;Knorr, Christoph
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권10호
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    • pp.1491-1500
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    • 2019
  • Objective: European pigs have been imported to improve the economically important traits of Thai pigs by crossbreeding and was finally completely replaced. Currently Thai indigenous pigs are particularly kept in a small population. Therefore, indigenous pigs risk losing their genetic diversity and identity. Thus, this study was conducted to perform large-scale genetic diversity and phylogenetic analyses on the many pig breeds available in Thailand. Methods: Genetic diversity and phylogenetics analyses of 222 pigs belonging to Thai native pigs (TNP), Thai wild boars (TWB), European commercial pigs, commercial crossbred pigs, and Chinese indigenous pigs were investigated by genotyping using 26 microsatellite markers. Results: The results showed that Thai pig populations had a high genetic diversity with mean total and effective ($N_e$) number of alleles of 14.59 and 3.71, respectively, and expected heterozygosity ($H_e$) across loci (0.710). The polymorphic information content per locus ranged between 0.651 and 0.914 leading to an average value above all loci of 0.789, and private alleles were found in six populations. The higher $H_e$ compared to observed heterozygosity ($H_o$) in TNP, TWB, and the commercial pigs indicated some inbreeding within a population. The Nei's genetic distance, mean $F_{ST}$ estimates, neighbour-joining tree of populations and individual, as well as multidimensional analysis indicated close genetic relationship between Thai indigenous pigs and some Chinese pigs, and they are distinctly different from European pigs. Conclusion: Our study reveals a close genetic relationship between TNP and Chinese pigs. The genetic introgression from European breeds is found in some TNP populations, and signs of genetic erosion are shown. Private alleles found in this study should be taken into consideration for the breeding program. The genetic information from this study will be a benefit for both conservation and utilization of Thai pig genetic resources.

소규모 매립지에 대한 메탄발생속도상수(k) 산출 및 온실가스 발생량 평가 (Evaluation of Methane Generation Rate Constant(k) by Estimating Greenhouse Gas Emission in Small Scale Landfill)

  • 이원재;강병욱;조병렬;이상우;연익준
    • 한국지반환경공학회 논문집
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    • 제15권5호
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    • pp.5-11
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    • 2014
  • 본 연구에서는 현재 사용 중인 2곳(H, Y 매립지)의 소규모 매립장에 대한 매립지 특성 자료수집과 현장측정을 통한 LFG 배출량 산정을 수행하였으며, 이를 이용하여 이들 매립지에 적합한 2006 IPCC FOD 방법 적용 시 입력변수로 사용되는 메탄발생속도상수(k)를 산출하여 보았다. 또한 이 결과를 default 값을 적용한 2006 IPCC GL의 FOD 방법에 의한 메탄 배출량 산정결과와 비교함으로써 특정매립지에 대한 동일한 k값 적용의 타당성을 평가해 보았다. 매립지의 폐기물 조성 data를 이용한 DOC 산정 결과, 매립되어지는 폐기물의 물리적 조성 차이로 인하여 H 매립지(1997~2011)는 13.16 %~23.79 % ($16.52{\pm}3.84%$)로 나타났으며, Y 매립지(1994~2011)는 7.24 %~34.67 % ($14.56{\pm}7.30%$)의 값을 보여 IPCC 가이드라인에서 제시한 Bulk waste 타입의 기본값인 18.0 %와 비교할 때 H 매립지보다 Y 매립지가 큰 차이를 보였다. 2006 IPCC GL에 제시된 FOD방법의 메탄 배출량 산정식을 이용한 k값 산정 결과, H 매립지의 산정된 평균 k값은 $0.0413yr^{-1}$, Y 매립지의 산정된 평균 k값은 $0.0117yr^{-1}$로 나타나 IPCC 가이드라인에 제시된 기본값인 $0.09yr^{-1}$에 비하여 상대적으로 낮은 값을 보였다. 따라서 2006 IPCC 가이드라인의 defaults value(k=0.09) 값에 의한 온실가스 배출량 산정결과는 현장측정을 통해 산정된 k값에 의한 추정값에 비하여 과대평가될 수 있어 매립지에서 발생하는 정확한 온실가스 배출량 예측을 위해서는 각각의 매립지별 현장측정을 통한 고유의 k값 결정을 통한 산정이 진행되어야 할 것으로 판단된다.

A one-dimensional model for impact forces resulting from high mass, low velocity debris

  • Paczkowski, K.;Riggs, H.R.;Naito, C.J.;Lehmann, A.
    • Structural Engineering and Mechanics
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    • 제42권6호
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    • pp.831-847
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    • 2012
  • Impact from water-borne debris during tsunami and flood events pose a potential threat to structures. Debris impact forces specified by current codes and standards are based on rigid body dynamics, leading to forces that are dependent on total debris mass. However, shipping containers and other debris are unlikely to be rigid compared to the walls, columns and other structures that they impact. The application of a simple one-dimensional model to obtain impact force magnitude and duration, based on acoustic wave propagation in a flexible projectile, is explored. The focus herein is on in-air impact. Based on small-scale experiments, the applicability of the model to predict actual impact forces is investigated. The tests show that the force and duration are reasonably well represented by the simple model, but they also show how actual impact differs from the ideal model. A more detailed three-dimensional finite element model is also developed to understand more clearly the physical phenomena involved in the experimental tests. The tests and the FE results reveal important characteristics of actual impact, knowledge of which can be used to guide larger scale experiments and detailed modeling. The one-dimensional model is extended to consider water-driven debris as well. When fluid is used to propel the 1-D model, an estimate of the 'added mass' effect is possible. In this extended model the debris impact force depends on the wave propagation in the two media, and the conditions under which the fluid increases the impact force are discussed.

User Bandwidth Demand Centric Soft-Association Control in Wi-Fi Networks

  • Sun, Guolin;Adolphe, Sebakara Samuel Rene;Zhang, Hangming;Liu, Guisong;Jiang, Wei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제11권2호
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    • pp.709-730
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    • 2017
  • To address the challenge of unprecedented growth in mobile data traffic, ultra-dense network deployment is a cost efficient solution to offload the traffic over some small cells. The overlapped coverage areas of small cells create more than one candidate access points for one mobile user. Signal strength based user association in IEEE 802.11 results in a significantly unbalanced load distribution among access points. However, the effective bandwidth demand of each user actually differs vastly due to their different preferences for mobile applications. In this paper, we formulate a set of non-linear integer programming models for joint user association control and user demand guarantee problem. In this model, we are trying to maximize the system capacity and guarantee the effective bandwidth demand for each user by soft-association control with a software defined network controller. With the fact of NP-hard complexity of non-linear integer programming solver, we propose a Kernighan Lin Algorithm based graph-partitioning method for a large-scale network. Finally, we evaluated the performance of the proposed algorithm for the edge users with heterogeneous bandwidth demands and mobility scenarios. Simulation results show that the proposed adaptive soft-association control can achieve a better performance than the other two and improves the individual quality of user experience with a little price on system throughput.

성능, 사용성, 환경성 평가를 통한 소형온풍기 설계안 개발 사례 (A Case Study of Eco-Design for a Small-Size Electric Heater by Performance, Usability, and Life-Cycle Assessments)

  • 이백희;유희천
    • 대한산업공학회지
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    • 제40권2호
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    • pp.223-232
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    • 2014
  • Life-cycle assessment (LCA) is often employed to quantify the environmental impact of a product in a comprehensive manner. The aspects of performance and usability as well as that of eco-friendliness should be considered in an integrated manner for the market competitiveness of an eco-friendly product. The present study developed a product improvement plan for an eco-friendly electric heater by benchmarking two small-size electric heaters (companies 'H' and 'T') in terms of performance, usability, and eco-friendliness. The performance measurements such as temperature, humidity, wind speed, noise, and power consumption were collected while the two heaters were operated in a laboratory setting. Then, the usability evaluations such as aesthetics, operation satisfaction, performance satisfaction, and overall satisfaction were surveyed for the two heaters using a 5-point scale (1 for very unsatisfied and 5 for very satisfied). Lastly, the LCA analysis was conducted by following the six-step process of eco-friendly product design provided by KEITI. The analysis results of the two products being integrated with the aspects of product, service, and user, four design improvement directions such as eco-efficient, smart, modularized, and user-support were recommended for an eco-friendly electric heater. These proposed concepts would be useful to develop an eco-friendly electric heater design with a high level of market competitiveness.

Seismic behavior of reinforced concrete interior beam-column joints with beams of different depths

  • Xing, G.H.;Wu, T.;Niu, D.T.;Liu, X.
    • Earthquakes and Structures
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    • 제4권4호
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    • pp.429-449
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    • 2013
  • Current Design Codes for Reinforced Concrete (RC) interior beam-column joints are based on limited experimental studies on the seismic behavior of eccentric joints. To supplement existing information, an experimental study was conducted that focused on the effect of eccentricity of the deeper beams with respect to the shallow beams. A total of eight one-third scale interior joints with beams of different depths were subjected to reverse cyclic loading. The primary variables in the test specimens were the amount of joint transverse reinforcement and the cross section of the shallow beams. The overall performance of each test assembly was found to be unsatisfactory in terms of joint shear strength, stiffness, energy dissipation and shear deformation. The results indicated that the vertical eccentricity of spandrel beams in this type of joint led to lower capacity in joint shear strength and severe damage of concrete in the joint core. Increasing the joint shear reinforcement was not effective to alter the failure mode from joint shear failure to beam yielding which is favorable for earthquake resistance design, whereas it was effective to reduce the crack width at the small loading stages. Based on the observed behavior, the shear stress of the joint core was suggested to be kept as low as possible for a safe and practical design of this type of joint.