• 제목/요약/키워드: small-scale H

검색결과 422건 처리시간 0.028초

Small dose of naloxone as an adjuvant to bupivacaine in intrapleural infiltration after thoracotomy surgery: a prospective, controlled study

  • Amer, Asmaa Fawzy;Omara, Amany Faheem
    • The Korean Journal of Pain
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    • 제32권2호
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    • pp.105-112
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    • 2019
  • Background: Severe pain always develops after thoracotomy; intrapleural regional analgesia is used as a simple, safe technique to control it. This study was performed to evaluate whether a small dose of naloxone with local anesthetics prolongs sensory blockade. Methods: A prospective, randomized double-blinded controlled study was conducted on 60 patients of American Society of Anesthesiologists statuses I and II, aged 18 to 60 years, scheduled for unilateral thoracotomy surgery. After surgery, patients were randomly divided into two groups: through the intrapleural catheter, group B received 30 ml of 0.5% bupivacaine, while group N received 30 ml of 0.5% bupivacaine with 100 ng of naloxone. Postoperative pain was assessed using the visual analog pain scale (VAS). Time for the first request for rescue analgesia, total amount consumed, and incidence of postoperative complications were also recorded. Results: The VAS score significantly decreased in group N, at 6 h and 8 h after operation (P < 0.001 for both). At 12 h after injection, the VAS score increased significantly in group N (P < 0.001). The time for the first request of rescue analgesia was significantly longer in group N compared to group B (P < 0.001). The total amount of morphine consumed was significantly lower in group N than in the bupivacaine group (P < 0.001). Conclusions: Addition of a small dose of naloxone to bupivacaine in intrapleural regional analgesia significantly prolonged pain relief after thoracotomy and delayed the first request for rescue analgesia, without significant adverse effects.

전국 중소업체 생산 고추장의 품질 특성 평가 (Evaluation of Quality Characteristics for Gochujang Produced by Small- and Medium-scale Manufacturers)

  • 이슬;조전호;유선미;박보람;한혜민;김하윤
    • 한국식품과학회지
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    • 제46권3호
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    • pp.309-314
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    • 2014
  • 대기업 생산 고추장의 소비 증가로 인한 고추장 특성의 획일화를 개선하기 위해 전국의 중소업체 생산 고추장 29종을 강원도, 경기도, 경상도, 전라도, 충청도에서 수집하여 품질 특성을 분석하였다. 수집된 고추장의 지역별 평균값은 수분함량 34.32-45.53%, 조단백질 함량 5.07-5.68%, pH 4.61-4.92, 산도 3.30-3.72%, 염도 9.93-16.14%의 범위를 보이는 것으로 측정되었다. 또한 환원당 함량이 16.81-29.81%, 아미노태질소 함량이 191.72-660.55 mg%, 캡사이시노이드 함량이 32.49-79.58 mg/kg로 나타나 지역별로 유의적인 차이를 보였으며, ${\alpha}$-amylase 활성과 ${\beta}$-amylase 활성은 각각 2.52-4.15 U/g과 26.36-36.47 U/g의 범위로 측정되었다. 또한 전체 중소업체 생산 고추장의 경우 수분함량 23.93-55.64%, 조단백질 함량 4.01-7.30%, 아미노태질소 함량 105.47-1092.00mg%, 캡사이시노이드 함량 8.74-181.50mg/kg으로 다양한 분포를 보이는 것으로 나타났고 대부분 한국산업표준(KS)에 적합하였다.

Dynamic Respiratory Measurements of Corynebacterium glutamicum using Membrane Mass Spectormetry

  • Wittmann.Christoph;Yang, Tae-Hoon;Irene Kochems;Elmar Heinzle
    • Journal of Microbiology and Biotechnology
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    • 제11권1호
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    • pp.40-49
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    • 2001
  • The present work presents a novel approach for the dynamic quantification of respiration rates on a small scale by using lysine-producing Corynebacterium glutamicum ATCC 21253. Cells sampeld from batch cultures at different times were incubated ina 12-ml scale bioreactor equipped with a membrane mass spectrometer. Under dynamic conditions, gas exchange across the gas-liquid phase, specific respiration rates, and RQ values were precisely measured. For this purpose, suitable mass balances were formulated. The transport coefficients for $O_2$ and $CO_2$, crucial for calculating the respiration activity, were determined as $k_La_{O2}=9.18h^{-1}$ and $k_La_{CO2}=5.10h^{-1}$ at 400 rpm. The application of the proposed method to batch cultures of C. glutamicum ATCC 21253 revealed the maximum specific respiration rates of $q_{O2}=8.4\;mmol\;g^{-1}h^{-1}\;and\;q_{CO2}=8.7\;mmol\;g^{-1}h^{-1}$ in the middle of the exponential growth phase after 5 h of cultivation. When the cells changed from growth to lysine production due to the depletion of the essential amino acids theonine, methionine, and leucine, $q_{O2}\;and\;q_{CO2}$ decreased significantly and RQ increased. The respiration data exhibited an excellent agreement with previous cultivations of the strain [13]. This confirms the potential of the developed approach to realistically reflect the metabolic activities of cells at their point of sampling. The short-term influence of added threonine, methionine, and leucine was highest during the shift from growth to lysine production, where $q_{O2}\;and\;q_{CO2}$ increased 50% within one minute after the pulse addition of these compounds. Non-growing, yet lysine-producing cells taken from the end of the batch cultivation revealed no metabolic stimulation with the addition of threonine, methionine, and leucine.

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H형강 매입형 합성기둥의 부착강도 및 전단연결재의 전단거동 (Bond Strength between Concrete and Steel and Shear Behavior of Shear Connectors of H-shaped Steel Encased Composite Columns)

  • 왕녕;이혜림;이명재
    • 한국강구조학회 논문집
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    • 제29권5호
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    • pp.377-387
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    • 2017
  • 이 연구에서는 강판 매입형 합성기둥의 Push-out Test를 통해 강재와 콘크리트의 부착면적에 따른 영향을 알아보았다. 이로써 부착면적이 넓을수록 부착응력은 작아진다는 경향이 조사되었다. 또한 소규모 매입형 합성기둥의 경우에는 설계기준에서 제시하는 공칭부착 응력값이 과소하게 적용되는 것을 확인하였다. 다음으로 H형강 매입형 합성기둥의 Push-out Test를 통해 전단연결재의 수와 간격에 따른 영향을 알아보았다. 이로써 전단연결재의 전단거동을 파악할 수 있었다.

초고속열차용 LSM 설계 검증을 위한 회전형 구조의 LSM 및 시험기 설계 연구 (Study on the Design of a Rotary-type LSM and Test Equipment for Design Verification of LSM for Ultra-high-speed Train)

  • 박찬배
    • 한국철도학회논문집
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    • 제20권2호
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    • pp.196-202
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    • 2017
  • 초고속열차 추진용 실모델 선형동기전동기(Linear Synchronous Motor, LSM)의 고속운전시험을 위해서는 매우 긴 노선이 필요하고, 이로 인해 막대한 비용이 요구되며, 개발 도중 시행오차가 발생할 경우 경제적 손실이 크게 발생할 우려가 있다. 따라서 저 비용의 축소모델을 이용한 LSM 설계 기술의 타당성 검증 연구가 개발 초기 단계에 이루어져야 한다. 회전형 구조를 갖는 LSM 축소모델을 적용한 성능시험기를 통하여 LSM의 지상전기자 권선의 최적방식 도출 및 기기적 특성 파악이 가능하며, 제어시스템의 선행연구 수행에 활용이 가능하다. 따라서 본 논문에서는 600km/h급 초고속열차 추진용 LSM의 요구사양에 부합하는 회전형 시험기의 설계 모델을 도출하고, 전자계 해석 및 기구적 강성 해석을 통하여 1500rpm 이상의 고속 회전 조건에서의 최적 모델을 도출하였다.

한식 간장의 이화학 및 관능적 특성 - 대기업 시판 제품과 경기지역 소규모 농가 생산 제품의 비교 - (Physico-Chemical and Sensory Properties of Commercial Korean Traditional Soy Sauce of Mass-Produced vs. Small Scale Farm Produced in the Gyeonggi Area)

  • 최남순;정서진;최지연;김혜원;조정주
    • 한국식품영양학회지
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    • 제26권3호
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    • pp.553-564
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    • 2013
  • The core ingredient of traditional Korean style soy sauce is soy bean without any wheat or rice incorporated. National brands as well as regional micro-brewed companies constitute the soy sauce market in Korea. The present study investigated the physico-chemical and sensory properties of soy sauces produced by small-scale or mass-production. Additionally, the key physico-chemical parameters sufficiently representing the critical sensory characteristics have been identified. Ten types of soy sauce brewed by the Korean traditional method were selected for the study. Among these samples, seven types were brewed in small-scales in the Gyeonggi-do region whereas the other 3 types were mass-production products of major national brands. The total solid, reducing sugar, salinity, sugar content, amino nitrogen, CIELAB, acidity, and pH of soy sauce samples were measured for the physico-chemical analysis. A generic descriptive analysis was conducted to analyze the sensory characteristics of the samples using six trained panelists. The descriptive panel developed 21 sensory attributes. The data were statistically analyzed using ANOVA, PCA and PLSR. Overall, the micro-brewed products showed significantly higher value of salinity and acidity but lower content of reducing sugar than the mass-production products. The micro-brewed soy sauces elicited stronger fermented flavor, sourness, and bitterness whereas the national brand products elicited stronger alcoholic odor, sweetness and umami taste. Sugar content, acidity, and amino nitrogen showed strong relationships with fish sauce flavor, umami taste, and rich flavor. Salinity was closely related to the overall flavor intensity.

A comparative investigation of the TTU pressure envelope -Numerical versus laboratory and full scale results

  • Bekele, S.A.;Hangan, H.
    • Wind and Structures
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    • 제5권2_3_4호
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    • pp.337-346
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    • 2002
  • Wind tunnel pressure measurements and numerical simulations based on the Reynolds Stress Model (RSM) are compared with full and model scale data in the flow area of impingement, separation and wake for $60^{\circ}$ and $90^{\circ}$ wind azimuth angles. The phase averaged fluctuating pressures simulated by the RSM model are combined with modelling of the small scale, random pressure field to produce the total, instantaneous pressures. Time averaged, rsm and peak pressure coefficients are consequently calculated. This numerical approach predicts slightly better the pressure field on the roof of the TTU (Texas Tech University) building when compared to the wind tunnel experimental results. However, it shows a deviation from both experimental data sets in the impingement and wake regions. The limitations of the RSM model in resolving the intermittent flow field associated with the corner vortex formation are discussed. Also, correlations between the largest roof suctions and the corner vortex "switching phenomena" are observed. It is inferred that the intermittency and short duration of this vortex switching might be related to both the wind tunnel and numerical simulation under-prediction of the peak roof suctions for oblique wind directions.

카본나노튜브가 액정의 물성과 Twisted Nematic 액정 셀의 전기광학 특성에 미치는 영향 (Carbon Nanotube Effects on Physical Properties of Liquid Crystal and Electro-Optic Characteristics of Twisted Nematic Liquid Crystal Cell)

  • 전상연;정석진;정석호;신승환;안계혁;이승은;이승희;이영희
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 학술대회 및 기술세미나 논문집 디스플레이 광소자
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    • pp.41-42
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    • 2006
  • Carbon nanotubes (CNTs) effects on physical properties of the liquid crystal and twisted nematic (TN) liquid crystal (LC) cells have been investigated. The minute doping of CNTs reduces rotational viscosity of the LC, and thus switching time of the TN cells is improved, especially in grey scale response time. In addition, the dielectric anisotropy and birefringence are not affected by such a small amount of CNT-doping and thus voltage-dependent transmittance remains the same.

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백운산 지역내 중소형 양어장에 의한 계류수의 이화학적 요인의 변화 (Changes on the Physicochemical Factor of Stream Water by Medium and Small type Fish Farm in Mt. Baegun Area)

  • 박재현
    • 한국환경복원기술학회지
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    • 제8권3호
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    • pp.43-52
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    • 2005
  • Evaluations of the fish farm influences on stream water quality may provide basic informations on watershed management to reduce environmental impact due to fish farm development and to conserve stream water quality in forested watershed area. In this research influent, effluent water in the fish farm and stream water qualities around Mt. Baegun area were monitored seasonally for six years and the following results were obtained. Due to the increase of pH in effluent water from the fish farm it was believed that alkalization of stream water can be accelerated by large scale development of fish farms in the forested watershed area. Also, effluent water from the fish farm increase of EC higher than influent and stream water. As a result of regression analyses, pH, EC, DO, water temperature, total amount of cation and anion in influent and effluent water of fish farm show high significance.

First Record of the Genus Halectinosoma (Copepoda: Harpacticoida: Ectinosomatidae) with Redescription of H. perforatum from Korea

  • Kim, Jong Guk;Jung, Tae Won;Yoon, Seong Myeong
    • 환경생물
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    • 제33권2호
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    • pp.132-139
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    • 2015
  • The genus Halectinosoma Vervoort, 1962 is first reported from Korean waters by the discovery of H. perforatum $It{\hat{o}}$, 1981. This species, previously recorded only from Japan, is collected from the sandy beach on the south coast of Korea, and is well distinguished from other congeners by the combination of following morphological characteristics: the elongate caudal ramus; the remarkably bilobated exopod of female P5; the small innermost seta on the distal margin of female P5 exopod; the presence of three setae on the distal exopodal segment in P4; and the presence of scale-like spinules on the ventral surfaces of urosomite. We herein provide detailed description and illustrations of this species.