• Title/Summary/Keyword: small samples

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Integrating Spatial Proximity with Manifold Learning for Hyperspectral Data

  • Kim, Won-Kook;Crawford, Melba M.;Lee, Sang-Hoon
    • Korean Journal of Remote Sensing
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    • v.26 no.6
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    • pp.693-703
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    • 2010
  • High spectral resolution of hyperspectral data enables analysis of complex natural phenomena that is reflected on the data nonlinearly. Although many manifold learning methods have been developed for such problems, most methods do not consider the spatial correlation between samples that is inherent and useful in remote sensing data. We propose a manifold learning method which directly combines the spatial proximity and the spectral similarity through kernel PCA framework. A gain factor caused by spatial proximity is first modelled with a heat kernel, and is added to the original similarity computed from the spectral values of a pair of samples. Parameters are tuned with intelligent grid search (IGS) method for the derived manifold coordinates to achieve optimal classification accuracies. Of particular interest is its performance with small training size, because labelled samples are usually scarce due to its high acquisition cost. The proposed spatial kernel PCA (KPCA) is compared with PCA in terms of classification accuracy with the nearest-neighbourhood classification method.

Determination of MDMA and MDA in 44 hair samples during 2002 to 2003

  • Han, Eun-Young;Yang, Won-Kyung;Lee, Jae-Sin;Park, Yong-Hoon;Kim, Eun-Mi;Lim, Mi-Ae;Chung, Hee-Sun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.112.1-112.1
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    • 2003
  • The qualitative and quantitative analysis of MDMA and MDA in hair samples by GC/MS were reported. Hairs were collected from subjects aged 22-37 years, who were suspected of abusing MDMA. After washing with methanol, hair samples were cut into small pieces, extracted with methanol containing 1 percent hydrochloric acid for 20th, and the solution was evaporated. MDMA or MDA in the extract were determined by GC/MS using selected ion monitoring after derivatization with trifluoroacetic anhydride. (omitted)

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Study on the Closure Time in Healthy Small-Breed Dogs by Platelet Function Analyzer-200

  • Kyoungyoun Lee;Yoonhee Kim;Ulsoo Choi
    • Journal of Veterinary Clinics
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    • v.40 no.5
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    • pp.330-335
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    • 2023
  • Platelet function evaluation by PFA-100 or -200 has been known to be objective and sensitive for assessing platelet function and dysfunction of Von Willebrand Factor in humans and dogs. However, using the C/EPI cartridge in dogs is controversial. This study aimed to establish a reference range for PFA closure time in healthy small breed dogs (body weight < 10 kg) and to evaluate the effectiveness of both C/ADP and C/EPI cartridges for these dogs. Citrated blood samples were collected from 50 clinically healthy small breed dogs that were admitted for presurgical procedures or health checkups, and closure times were measured using the PFA-200. Reference ranges were determined as 42-144 s (median 67 s, mean 71.2 s, SD ± 21.2 s, 95% RI 43-140 s) , for CT-C/ADP and 41-200 s (median 87, mean 91.2 s, SD ± 31.8 s, 95% RI 44-195 s) for CT-C/EPI. The present study demonstrated that the reference ranges for PFA closure times in small breed dogs are in line with existing reference ranges. The utilization of C/ADP cartridges is the preferred choice for evaluating platelet function in small breed dogs. However, due to variable responses of epinephrine to platelet aggregation in dogs, caution should be exercised when using C/EPI cartridges.

Mechanical Property and Crystallization of Glass by Femtosecond Laser Pulses (Femto Second Laser Pulse에 의한 유리의 결정화 및 기계적 특성)

  • Cha, Jae-Min;Moon, Pil-Yong;Kim, Dong-Hyun;Park, Sung-Je;Cho, Sung-Rak;Ryu, Bong-Ki
    • Journal of the Korean Ceramic Society
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    • v.42 no.6 s.277
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    • pp.377-383
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    • 2005
  • Generally, the strength achieved of glass-ceramics is higher as is the fracture toughness, as compared with the original glass. This improvement is due to the microstructure consisting of very small crystals. In this study, Ag-doped $45SiO_2-24CaO-24Na_2O-4P_2O_5$ glasses were irradiated to strengthen by the crystallization using Femto second laser Pulses. Through the UV/VIS spectroscope, XRD, Nano-indenter and SEM etc., heat-treated and irradiation of laser pulses without heat-treated samples were analyzed. Two kinds of samples, heat-treated and laser irradiated without heat-treated samples, showed the peaks in the same wavelength near 360 nm. Especially, samples irradiated by 140 mW laser with XYZ stage having at the rate of 100$\~$l000 $\mu$m/s had the largest absorption peak among them, and heat-treated samples was shown lower absorption range than over 90 mW laser irradiated samples. Moreover, samples irradiated by laser had higher values ($4.4\~4.56{\times}10^{-3}(Pa)$) of elastic modulus which related with strength of glass than values of heat-treated samples and these are 1.2$\~$1 .5 times higher values than them of mother glass.

High Feasibility of Liquid-Based Cytological Samples for Detection of EGFR Mutations in Chinese Patients with NSCLC

  • Wu, Chun-Yan;Hou, Li-Kun;Ren, Sheng-Xiang;Su, Bo;Chen, Gang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7885-7889
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    • 2014
  • Background: Activating mutations of epidermal growth factor receptor (EGFR) could predict response to tyrosine kinase inhibitor (TKI) treatment in patients with non-small cell lung cancer (NSCLC). However, the detection of EGFR mutation is frequently challenging in clinical practice for the lack of tumor tissue. The aim of this study was to investigate the feasibility of performing EGFR mutation testing on various types of liquid-based cytology (LBC) samples. Materials and Methods: A total of 434 liquid-based cytology samples were collected from March 2010 and November 2013. Among them, 101 with diagnosis of lung adenocarcinoma had paired surgically resected specimens. The ADx Amplification Refractory Mutation System (ADx-ARMS) was used to determine EGFR mutation status both in LBC and resected samples. Results: All liquid-based cytology samples were adequate for EGFR mutation analysis. The mutation rate was 50.5% in the 434 NSCLC patients with LBC samples and the incidence rates of EGFR mutation were consistent among different specimens. We also detected EGFR positives in 52.5% (53/101) patients with paired histologic specimens. The concordance rate of EGFR mutation between LBC samples and paired histologic specimens was 92.1%. Conclusions: Our results suggest that liquid-based cytology samples are highly reliable for EGFR mutation testing in patients with NSCLC.

A Study on the Least Squared Estimator of Autoregressive Models when Consecutive Missing Observations Exist

  • Ryu, Gui-Yeol
    • Communications for Statistical Applications and Methods
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    • v.3 no.3
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    • pp.59-74
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    • 1996
  • The properties of the residuals are investigated when K-consecutive observations are interpolated. The central limit theorem is also proved for the LSE for autoregressive parameters when $\kappa4--consecutive observations are contaminated. The performance of the interpolated LSE in small samples is investigated by simulation. And the interpolated with the Yule-Walker type estimator.

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Small and Large Deformation Rheological Behaviors of Commercial Hot Pepper-Soybean Pastes

  • Choi, Su-Jin;Kang, Kyoung-Mo;Yoo, Byoung-Seung
    • Food Science and Biotechnology
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    • v.15 no.6
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    • pp.871-876
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    • 2006
  • Rheological behavior of commercial hot pepper-soybean paste (HPSP) was evaluated in small amplitude oscillatory and steady shear tests. Storage modulus (G'), loss modulus (G"), and complex viscosity (${\eta}^*$) as a function of angular frequency (${\omega}$), and shear stress (${\sigma}$) as a function of shear rate (${\gamma}$) data were obtained for 5 commercial HPSP samples. HPSP samples at $25^{\circ}C$ exhibited a non-Newtonian, shear-thinning flow behavior with high yield stresses and their flow behaviors were described by power law, Casson, and Herschel-Bulkley models. Time-dependent flow properties were also described by the Weltman, Hahn, and Figoni & Shoemaker models. Apparent viscosity over the temperature range of $5-35^{\circ}C$ obeyed the Arrhenius temperature relationship with activation energies (Ea) ranging 18.3-20.1 kJ/mol. Magnitudes of G' and G" increased with an increase in ${\omega}$, while ${\eta}^*$ decreased. G' values were higher than G" over the most of the frequency range (0.63-63 rad/sec), showing that they were frequency dependent. Steady shear viscosity and complex viscosity of the commercial HPSP did not fit the Cox-Merz rule.

Application of Three-Dimensional Light Microscopy for Thick Specimen Studies

  • Rhyu, Yeon Seung;Lee, Se Jeong;Kim, Dong Heui;Uhm, Chang-Sub
    • Applied Microscopy
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    • v.46 no.2
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    • pp.93-99
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    • 2016
  • The thickness of specimen is an important factor in microscopic researches. Thicker specimen contains more information, but it is difficult to obtain well focused image with precise details due to optical limit of conventional microscope. Recently, a microscope unit that combines improved illumination system, which allows real time three-dimensional (3D) image and automatic z-stack merging software. In this research, we evaluated the usefulness of this unit in observing thick samples; Golgi stained nervous tissue and ground prepared bone, tooth, and non-transparent small sample; zebra fish teeth. Well focused image in thick samples was obtained by processing z-stack images with Panfocal software. A clear feature of neuronal dendrite branching pattern could be taken. 3D features were clearly observed by oblique illumination. Furthermore, 3D array and shape of zebra fish teeth was clearly distinguished. A novel combination of two channel oblique illumination and z-stack imaging process increased depth of field and optimized contrast, which has a potential to be further applied in the field of neuroscience, hard tissue biology, and analysis of small organic structures such as ear ossicles and zebra fish teeth.

Analysis of Productivity and Distribution of Female Workers in FB's Industries

  • Arfah, Aryati;Putra, Aditya Halim Perdana Kusuma
    • Journal of Distribution Science
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    • v.17 no.3
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    • pp.31-39
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    • 2019
  • Purpose - This study aims to investigate and analyze the factors that affect women's work productivity based on ethnic in the food and beverage industry. Also, it is also to determine whether there are differences in the productivity of female workers based on these ethnic groups. Research design, data, and Methodology - The approach of this research is quantitative by using multiple linear regression analysis and analysis of different tests using SPSS and tested on 114 samples of female workers in various small-scale, medium-sized food and beverage industry categories and large in Makassar City, Indonesia. Determination of samples based on proportional stratified sampling. Industry sampling criteria based on some workers, assets and wealth. Results and Conclusions - The results of this study state that health, years of service, work ethic, age, wages, and work environment have a significant effect on work productivity. While the level of education, the number of dependents does not have a considerable impact, the fact that there is a difference in the productivity index of female workers in a significant sector is compared to small and medium scale enterprises, including the variables of government policies related to pension insurance, work accident insurance and health insurance.

SALS Study on Transcrystallization and Fiber Orientation in Glass Fiber/Polypropylene Composites

  • Na, Kun;Park, Han-Soo;Won, Hong-Youn;Lee, Jong-Kwan;Lee, Kwang-Hee;Nam, Joo-Young;Jin, Byung-Suk
    • Macromolecular Research
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    • v.14 no.5
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    • pp.499-503
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    • 2006
  • This report presents a new technical approach for evaluating the fiber orientation of composites using small-angle light scattering (SALS). Glass fiber (GF)/polypropylene (PP) composites with different fiber orientations were prepared by drawing compression-molded specimens. The drawn samples were remelted and then annealed at $150^{\circ}C$ in order to induce a crystalline structure on the fiber surface, and then underwent SALS analysis. The samples showed a combination of circular and streak patterns. The model calculations demonstrated that the number of nuclei on the fiber surface and the thickness of the transcrystalline layer affected the sharpness and intensity of the streak pattern. In addition, the azimuthal angle of the streak pattern was found to be dependent on the direction of the transcrystalline layer, which correlated with the fiber direction. This correlation suggests that the fiber orientation in the composites can be easily evaluated using SALS.