• 제목/요약/키워드: small intestine

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가축(家畜) 및 실험동물(實驗動物) 소화관선(消化管腺)의 구조(構造)에 관한 연구 II. 포유(哺乳) mouse 장점막(腸粘膜)의 세포재생주기(細胞再生週期)에 대하여 (Studies on the digestive gland structures of domestic and experimental animals II. The renewal cycle of the cells in the intestinal mocosa of sucking mouse)

  • 곽수동
    • 대한수의학회지
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    • 제32권1호
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    • pp.1-6
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    • 1992
  • The turnover time of the mucosal epithelium in the small intestine(jejunum and ilium) and large interstine(cecum), and the cells in the lamina propria of the small intestine was investigated with the radioautography in mice at various times after single injection of $^3H$-thymidine. Twenty suckling mice were sacrified at each of the following time intervals after injection ; 2 hrs, 1, 3, 5. 7, 14 and 17 days. 1. The labeled index of the epithelial cells in the crypt and the villus of the small intestine averaged 98.7% and 1.3% at 2 hrs, 982% and 1.8% at 1 day, 18.7% and 81.3% at 3 days, 6.3% and 93.7% at 5 days, respectively. The labeled index of the epithelial cells of the crypt-base, the upper-crypt and the mucosal surface in the large intestine averaged 71.8%, 28.2% and 0% at 2 hrs, 45%. 54.2% and 0% at 1 day, 17.2%, 54.5% and 28.2% at 3 days, 10.2%, 32.4% and 57.4% at 5 days, respectively. This result suggested that the turnover time of all the epithelial cells migrating from crypts to villi in the direction of the villus tips was calculated to be less than 5 days, and also the longest turnover time was calculated to be no longer than 7 day. 2. The labeled index of the total cells in the lamina propria of the small intestine averaged 6.2-7% at 2 hrs to 5 days, 4.7% at 7 days 2.6% at 17 days and this index is tend to be decreased moderately at 7 days and severely at 17 days. So this result suggested that the turnover time of the cells with the shorter cycle duration in the lamina propria of the small intestine were less than 5 days and that of the cells with the longer cycle duration more than 17 days.

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접촉반사분석법을 이용한 수태양경근의 근육 활성도에 대한 연구 (Study of the Muscle Activity of Small Intestine Channel of Hand Taiyang Muscle Using Contact Reflex Analysis)

  • 이광규;오종현;이상룡
    • 동의생리병리학회지
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    • 제26권6호
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    • pp.947-952
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    • 2012
  • This Study was conducted to investigate Muscle Test of Point Selection through CRA(Contact Reflex Analysis) Muscel Diagnosis. So this study used to compare and analyze the effects of Muscel(Deltoid Muscel of Posterior) RMS(Root Mean Squared) and MEF(Median Edge Frequency) Among Groups that do not respond to questionnaire, Tonguibogam Naegyeongpyeon Small Intestine Group, Small Intestine MeridianPathway Primary Symptom and Secondary Symptom Group and Kwanwon(CV4) meridian Principal action Group. The questionnaire is composed of 23 items. The questionnaire was intended to elicit information on assorting into 4 groups. After Survey, Subject had to Muscle test subjects. Muscle experimental methods are as follows: Holding the shoulder without contacting Kwanwon. Holding the shoulder contacting Kwanwon. The first iteration. Group 1,2,3 were increased sEMG RMS compared with First experiment and Second experiment. Group 4(Including Uterus and Intestinal Flora Problem) were decreased sEMG RMS compared with First experiment and Second experiment. This test means that it is similar to diagnosis CRA and Small intestine channel of hand taiyang muscle, not Small Intestine MeridianPathway. It is suggested that subjects with a Small Intestine problem(Uterus and Intestinal Flora Problem) shows the results of decreasing posterior Deltoid Muscular strength. It means that CRA muscle diagnosis is associated with Alarm points diagnosis. But it doesn't consider influence of fat on the surface EMG.

수태양소장경근(手太陽小腸經筋)에 대한 근육학적(筋肉學的) 고찰(考察) (The study of muscular system about small intestine channel of hand taiyang muscle)

  • 김지남;김영일;홍권의;임윤경;이현
    • 혜화의학회지
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    • 제14권1호
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    • pp.67-81
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    • 2005
  • We have conclusions after the study of muscular system about small intestine channel of hand taiyang muscle. Judging from many studies of interrelation between Meridian muscle and muscle, it is considered that Meridian muscle theory has some similarities with modern anatomical muscular system. It is considered that Small intestine channel of hand taiyang muscle contains Flexor digitorum profundus muscle, Extensor digiti minimi muscle, Abductor digiti minimi muscle, Extensor carpi ulnaris muscle, Flexor carpi ulnaris muscle, Triceps brachii muscle, Infraspinatus muscle, Levator scapulae muscle, Sternocleidomastoid muscle, Masseter muscle, Temporalis muscle. The symptoms of small intestine channel of hand taiyang muscle is similar to referred pain of modern Myofascial Pain Syndrome, and the medical treatment of "I Tong Wi Su(以痛爲輸)" is also similar to that of Myofascial Pain Syndrome. Small intestine channel of hand taiyang muscle is one of the three yang channels of hand muscle, and it has unity in extension of upper limb and trunk in the movement. And it is thought that weakness of small intestine channel of hand taiyang muscle is related with muscular system causing Round Shoulder and Head Forward Position.

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Recent insights into the role of ChREBP in intestinal fructose absorption and metabolism

  • Lee, Ho-Jae;Cha, Ji-Young
    • BMB Reports
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    • 제51권9호
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    • pp.429-436
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    • 2018
  • Fructose in the form of sucrose and high fructose corn syrup is absorbed by the intestinal transporter and mainly metabolized in the small intestine. However, excess intake of fructose overwhelms the absorptive capacity of the small intestine, leading to fructose malabsorption. Carbohydrate response element-binding protein (ChREBP) is a basic helix-loop-helix leucine zipper transcription factor that plays a key role in glycolytic and lipogenic gene expression in response to carbohydrate consumption. While ChREBP was initially identified as a glucose-responsive factor in the liver, recent evidence suggests that ChREBP is essential for fructose-induced lipogenesis and gluconeogenesis in the small intestine as well as in the liver. We recently identified that the loss of ChREBP leads to fructose intolerance via insufficient induction of genes involved in fructose transport and metabolism in the intestine. As fructose consumption is increasing and closely associated with metabolic and gastrointestinal diseases, a comprehensive understanding of cellular fructose sensing and metabolism via ChREBP may uncover new therapeutic opportunities. In this mini review, we briefly summarize recent progress in intestinal fructose metabolism, regulation and function of ChREBP by fructose, and delineate the potential mechanisms by which excessive fructose consumption may lead to irritable bowel syndrome.

닭의 대장을 돼지의 대장이나 소의 제 1위 (Rumen)와 비교 연구 (Comparison of the Chicken Large Intestine to the Large Intestine of Pigs and the Rumen of Cows)

  • 남기홍
    • 한국가금학회지
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    • 제33권1호
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    • pp.81-95
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    • 2006
  • 닭의 대장은 해부학적, 생리학적으로 돼지의 대장이나 소의 men과 다르다. 닭의 대장은 소의 men이나 돼지의 대장에 비교하여 잘 발달되어 있지 않다. 그러나 닭의 대장속에 있는 미생물군은 rumen 속의 것과 비슷하다. 특히 닭의 맹장속에는 많은 미생물이 있으며 이 미생물군은 나이, 사료, 성성숙의 정도, 항생제 사용 유무 등에 따라서 다양하게 나타난다. 단백질은 장내의 미생물 형성에 중요한 영양소이다. 닭에서 소장의 길이는 전장 길이의 65%를 차지하며 닭의 맹장은 8.1 %그리고 직장과 공장은 4.6 %를 차지한다. 소장 내에 분포하는 미생물 군은 현재까지 약 10%가 구명된 상태로서 나머지 90%에 대한 정보는 전무하다. 최근의 연구에 따르면 에너지, 저급지방산 (VFA)과 그리고 전해물질이 대장에서 약간씩 흡수되는 것으로 알려져 있다. 닭의 소장은 각종 효소등이 분비되어 소화가 일어나는 중추적인 역할을 하는 것으로 알려져 있다. 앞으로도 많은 연구가 과당류 즉 sucrose thermal oligosaccharide caramel (STOP), fructooligosaccharides (FOS), mannanoligosaccharide (MOS), galactooligosaccharide (GOS) 그리고 isomaltooligosaccharides (IMO)등이 맹장과 대장내에서 어떻게 소화가 일어나는지에 관해서 집중되어야 한다. 과량의 섬유질 함량은 닭의 소화에 치명적일 수 있지만 적당량을 사료에 혼합하여 급여하면 소장의 길이와 함량을 증가시킬 수 있는 효과가 있다.

발생기 흰쥐 위와 소장점막의 gastrin, somatostatin 및 serotonin세포에 대한 면역조직화학적연구 (Immunohistochemical Studv on the Gastrin, Somatostatin and Serotonin Cells in the Gastric and Small Intestinal Mucosa of Rat during Development)

  • 최병태;조운복
    • 한국동물학회지
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    • 제37권4호
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    • pp.478-487
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    • 1994
  • The developmental changes of three enteroendocrine cells, i.e. gastrln, somatostatin and serotonin, of gastric and small intestinal mucosa in pre- and postnatal rat were examined by peroxidase-antiperoxidase (PAP) method. In the course of development, gastrin cells were obsenred in the pyloric gland region and the whole part of small intestine, while somstostatin and serotonin cells in the whole gastric gland region and small intestine. More entroendocrine cells were detected in the pyloric gland region and duodenum than in the other portion. In the stomach, gastrin, somatostatin and serotonin ceils were first obsenred in the pyloric Bland region on 17, 19 and 19 days of gestation respectively. The small intestinal gastrin and serotonin cells were first appeared in the duodenum and iriunum on 17 and 15 days of gestation respectively, and somatostBtin cells in duodenum on 17 days of gestation. The number of cells examined from the stomach were increased from fetal to weanling period and showed a decrease during adult period: the notable increase was shown at the end of suckling period or at early weanling period. The cells of the small intestine increased from fetal to suckling period, especially, these cells markedly increased at the end of fetal period or at early suckling period, and decreased from weanling period. The shape of these cells was oval or fusiform during fetal period. In the stomach, most of gastrin cells turned out to be oval and open-type from suckling period, while the remaining two tripes of cells were oval and open- or closed-type. In the small intestine, 311%Ves of cells examined were changed to fusiform and open-type from the end of fetal period. Three types of cell were distributed over the stratified epithelium on 15 and 17 days of gestation. In the stomach, these cells were distributed lower gastric pit and gland from the following fetal period, and were detected mainly on the upper part of gland from suckling period, and then obsenred on the whole part of gland. In the small intestine, most of cells distributed over only between epithelium of villi on 19 days of gestation, increased in number on the crypt from following fetal period, and also observed abundantly in the crypt at adult period.

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재래산양(在來山羊)의 소장형성(小腸形成)에 관한 조직학적관찰(組織學的觀察) (Histological Observation on Development of the Small Intestine of the Korean Native Goat)

  • 곽수동;김종섭
    • 대한수의학회지
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    • 제25권1호
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    • pp.1-5
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    • 1985
  • The morphological development of the small intestinal tissues of the Korean native goat were observed by light microscopy. Samples were taken from a 60-, 90-, 120-day-old fetus, a newborn goat and a 30-day-old goat. The results were summarized as follows; 1. In the small intestine of 60-day-old fetus, the apexes and sides of villi were covered with a simple columnar epithelium, and intervilous areas and mucosal ridges were still covered with stratified epithelium of two to six cell layers. Mesenchymal tissues formed lamina propria, circular muscle layer and serosa. The numbers of villi per cross section of the small intestine (NVPCS) were 10 to 18. 2. In 90-day-old fetus, intervillous areas and mucosal ridges of the organ were covered with simple columnar epithelium. Goblet cells in epithelium and outer longitudinal muscle layer often appeared. NVPCS were 35 to 60 and Brunner's glands were appeared. 3. In 120-day-old fetus, Brunner's glands of the duodenum and circular connection of outer longitudinal muscle layer were formed, NVPCS were 50 to 87. 4. In newborn goat, Peyer's patches were fully formed and NVPCS were 50 to 87. 5. In 30-day goat, the small intestine was fully matured and NVPCS were 81 to 102.

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