• Journal of Periodontal and Implant Science
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• 제43권6호
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• pp.315-322
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• 2013

Purpose: In this study, we investigated the effect of silk scaffolds on one-wall periodontal intrabony defects. We conjugated nano-hydroxyapatite (nHA) onto a silk scaffold and then seeded periodontal ligament cells (PDLCs) or dental pulp cells (DPCs) onto the scaffold. Methods: Five dogs were used in this study. Bilateral 4 mm${\times}$2 mm (depth${\times}$mesiodistal width), one-wall intrabony periodontal defects were surgically created on the distal side of the mandibular second premolar and the mesial side of the mandibular fourth premolar. In each dog, four of the defects were separately and randomly assigned to the following groups: the PDLCcultured scaffold transplantation group (PDLC group), the DPC-cultured scaffold transplantation group (DPC group), the normal saline-soaked scaffold transplantation group, and the control group. The animals were euthanized following an 8-week healing interval for clinical, scanning electron microscopy (SEM), and histologic evaluations. Results: There was no sign of inflammation or other clinical signs of postoperative complications. The examination of cellseeded constructs by SEM provided visual confirmation of the favorable characteristics of nHA-coated silk scaffolds for tissue engineering. The scaffolds exhibited a firm connective porous structure in cross section, and after PDLCs and DPCs were seeded onto the scaffolds and cultured for 3 weeks, the attachment of well-spread cells and the formation of extracellular matrix (ECM) were observed. The histologic analysis revealed that a well-maintained grafted volume was present at all experimental sites for 8 weeks. Small amounts of inflammatory cells were seen within the scaffolds. The PDLC and DPC groups did not have remarkably different histologic appearances. Conclusions: These observations indicate that nHA-coated silk scaffolds can be considered to be potentially useful biomaterials for periodontal regeneration.

• Parasites, Hosts and Diseases
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• 제46권1호
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• pp.23-27
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• 2008

This study was designed to investigate the incidence of ectoparasite infestation among stray dogs in Gwang-ju City, Republic of Korea. A total of 103 stray dogs collected in the Animal Shelter of Gwang-ju City from November 2003 to August 2005 were investigated in this study. Ectoparasites of one or more genera were detected in 45.6% (47 /103) of the dogs examined for dermatologic lesions and/or skin scrapings (from 3-5 affected areas). Otodectes cynotis was found to be the most frequent parasite (22.3%, 23 / 103), followed by Sarcoptes scabiei var canis (19.4%, 20 / 103), Ctenocephalides canis (6.8%, 7 / 103), Demodex canis (4.9%, 5 / 103), and Trichodectes canis (1.0%, 1 / 103). Monospecific infestation was found in 83.0% (39 / 47) of the affected dogs, whereas concurrent infestations with 2 or more ectoparasites per animal were found in 17.0% (8 / 47) of the affected dogs. Trichodectes canis is reported for the first time in the Republic of Korea. Dogs less than 1 yr old were more heavily infected than other age groups (66.7%), and small-sized dogs of less than 3 kg body weight were more heavily infected than larger dogs (41.7%).

• 한국임상수의학회지
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• 제30권5호
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• pp.390-393
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• 2013

폐염전으로 진단한 소형견 4 마리의 흉부 방사선 사진 및 컴퓨터단층촬영 (CT) 영상을 평가하였다. 흉수 및 폐염전이 발생한 폐엽의 밀도 증가는 4 마리 환자의 흉부 방사선 사진 및 CT 영상에서 모두 확인되었다. 폐염전이 발생한 기시부에서의 기관지의 협착/허탈은 CT 영상을 통해 4 마리의 개에서 모두 확인된 반면, 흉부 방사선 사진에서는 오직 1 마리의 환자에서만 확인되었다. 폐포성 폐기종 패턴 (vesicular emphysema pattern) 역시, CT 영상을 통해 4 마리의 환자에서 모두 확인된 반면, 흉부 방사선 사진에서는 3 마리에서 관찰되었다. 폐염전의 특이소견은 폐포성 폐기종 패턴과 폐염전이 발생한 폐엽 기시부의 기관지의 협착/허탈이며, 이 소견은 흉부 방사선 사진보다 CT 영상을 통해 좀 더 용이하고 빈번하게 확인되었다.

• 대한전자공학회논문지
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• 제20권1호
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• pp.63-71
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• 1983

본 논문에서는 디지탈 감산 기법을 이용한 양면 혈관 조영술 영상에서의 대응점 결정을 위하여 조영제 말단 추적 알고리즘을 사용하였고, 이 대응점 정보로부터 혈관의 3차원 영상을 재구성하는 과정을 확립하였으며, 개를 이용한 실험 결과도 포함되어 있다. 저자들에 의해 개발된 본 방법의 정확성을 입증하기 위해 사각에서 잡은 혈관 조영상과 계산을 통해 재구성된 영상을 비교하여 좋은 결과를 얻었다. 본 논문에서는 3가지의 새로운 알고리즘을 개발, 또는 응용하였는바, 첫째는, 순차적인 영상에서 조영제의 말단은 어느 투영면에서도 동일한 형태를 갖게 되므로, 상호 상관 계수의 접합법을 이용하여 조영제 말단을 추적해 가는 알고리즘이고, 둘째는, 기준좌표계에서 시선좌표계로의 전환을 4×4행렬 하나로 표시한 단순화 투시 변환 행렬의 구성이며, 셋째는, 조영제 말단 추적법이 적용될 수 없는 작은 혈관 영상에서의 대응점 확립을 위한 보조알고리즘의 적용이 그것이다. 또한 본 방법은 3차원 공간상에서의 조영제 말단 이동거리에 대한 정보로부터 혈류속도의 측정에도 이용될 수 있다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.289-292
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• 2012

현재 대한민국에는 동록 되지 않은 시각장애인을 포함하여 20~30만 명의 시각장애인이 있다. 시각 장애인들은 보행을 할 때 주로 흰 지팡이(White Stick)를 사용하고 있다. 안내견의 도움을 받는 시각 장애인도 있지만 비용문제 등 여러 복합적인 문제로 인해 소수의 시각장애인만이 이용하고 있다. 현재 상용되어지고 있는 시각장애인을 위한 길 안내 서비스 보조기구는 시각장애인들이 사용하고 있는 흰 지팡이에 RFID태그를 부착하고, 이를 이용하여 표지블록과 RF통신을 하는 정도의 수준에 머무르고 있다. 이는 인식거리가 짧고, 명확한 장애물의 위치, 크기 및 형태를 판단하기 힘들기 때문에 실제 시각장애인들의 보행에 큰 도움이 되지 못하고 있는 실정이다. 이에 본 논문에서는 시각장애인들이 좀 더 수월하게 보행 할 수 있도록 Cortex-A8 Platform기반의 'Smart Portable Navigation System'개발에 대한 연구를 다루고자 한다.

• Archives of Plastic Surgery
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• 제33권1호
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• pp.101-106
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• 2006

Nipple reconstruction is an important step in breast reconstruction after mastectomy. The authors' preferred reconstructive technique is the local C-V flap in case that a small opposite nipple is not adequate for composite graft. This flap produces an excellent reconstruction, but it is not easy to produce an adequate projection and firmness of the nipple. This article describes the technique and experience in nine patients treated over two years with dermis(scar tissue) graft for nipple reconstruction. This is the first report of application of autologous dermis(scar tissue) grafting to reconstruct a nipple primarily after breast mound reconstruction, decreasing the absorption of the reconstructed nipple and increasing the hardness. The dermis(scar tissue) is taken from scar revision and/or dog-ear correction in the second stage operation after free TRAM flap breast reconstruction. And the dermis(scar tissue) graft is inserted vertically between the local flaps and horizontally under the reconstructed nipple base. Between September 2002 and February 2005, nine patients underwent C-V flap with dermis(scar tissue) graft as a part of their nipple reconstruction. The patient's ages ranged from 28 to 55 years old (mean, 41.1 years old). The follow-up period ranged from 5 to 35 months, with an average of 14.5 months. None of the nipples showed skin flap necrosis or local infection, and uneventful wound healing. Our result showed good nipple projection with less absorption and enough firmness. Our experiences shows that dermis(scar tissue) grafts in C-V flap is a very useful method for nipple reconstruction.

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어의학회 2003년도 제19회 학술대회
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• pp.181-181
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• 2003

Objectives : Vocal fold augmentation using injectable material is an easy and simple operation. This study is to evaluate the histology of minced and injected autologous auricular cartilage and fat graft in the augmentation of unilateral vocal fold paralysis using a canine model for two years. Study Design : A prospective study with the contralateral side of the larynx used as the control Methods : Twelve dogs were operated. At first, a piece of auricular cartilage was harvested from ear and minced into tiny chips with a scalpel and scissors. And also, a piece of fat tissue was harvested from inguinal area and minced into tiny chips with a scalpel and scissors. The minced cartilage and fat-paste (0.2ml) was injected using a pressure syringe into the paralyzed thyroarytenoid muscle under direct laryngoscopy. Two animals were sacrificed at 3 days, three at 3 weeks. two at 3 months. one at 6 months, one at 12 months, three at 24 months. Each dog underwent laryngectomy and serial coronal sections of paraffin blocks from the posterior part of the vocal fold were made. Result : There was no significant complication perioperatively and during follow-up. There was acute inflammatory findings in the graft at 3 days and 3 weeks. Only a very small proportion of the injected cartilage was absorbed due to the degenerative change and the overall volume was preserved even when the cells died out. The injected cartilage remained in the larynx until 24 months. Conclusion : The autologous cartilage implant using auricular cartilage was the ideal vocal cord augmentative material for the treatment of glottic incompetence.

• 한국수정란이식학회지
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• 제28권1호
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• pp.73-78
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• 2013

The present study examined the histological characteristics of adult testis in the long-beaked common dolphin (Delphinus capensis) from Korean waters and the localization of DEAD-box polypeptide 4 (DDX4; a germ cell marker) and vimentin (a Sertoli cell marker) expression in the dolphin testis compared with that in terrestrial mammals, including dogs and rats. The seminiferous tubules of dolphin testis have very small or completely closed lumens, and spermatogenic cells and Sertoli cells within the tubules cannot be differentiated. Immunohistochemical analysis showed that, in the dolphin testis, DDX4- and vimentin-positive cells were scattered extensively within the tubule, whereas in the dog and rat testis, DDX4 immunoreactivity was localized in spermatogenic cells of the adluminal compartment, and vimentin immunoreactivity was localized in Sertoli cells of the basal compartment in the seminiferous epithelium. These results suggest that the histological characteristics of the seminiferous tubules in the dolphin testis differ from those of terrestrial species.

• 한국임상수의학회지
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• 제37권2호
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• pp.82-87
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• 2020

The purpose of this study is to evaluate the azygos vein to aorta diameter ratio (AV/AO ratio) in healthy dogs and dogs with diseases that may cause azygos vein dilation. The normal groups included eleven healthy beagle dogs and eleven small breed dogs. The abnormal group included 43 dogs that had diseases with high right atrial pressure (RA group), obstruction of cranial or caudal vena cava (CVC group) and porto-azygos shunt group (PSS group). The diameter of AV and AO were measured at three sites on thoracic CT images; the level of the cranial endplate of 12^th thoracic vertebra (TV level), the tracheal bifurcation (TB level) and the insertion to the cranial vena cava (CrVC level). The AV/AO ratio at the CrVC level had significantly higher values than those at the TV and TB levels in the normal groups. The AV/AO ratios of TV and TB levels in the CVC group and the values at all measurement sites of the PSS group were significantly higher than the normal groups. AV/AO ratio will be a useful factor for the evaluation of various clinical conditions that change the AV diameter with respect independent to the body weight in dogs.

• 한국임상수의학회지
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• 제18권3호
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• pp.206-210
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• 2001

피부질환에는 보조 치료로 다양한 치료용 샴푸가 빈번하게 적용되고 있으나 이들 샴푸의 피부수분에 미치는 영향은 일반적으로 평가되지 않고 있는 실정이다. 따라서 치료용 샴푸의 정확한 처방을 위해서는 피부의 수분을 측정하기 위한 측정법이 필요하다. 본 연구는 여러 종류의 치료용 샴푸의 피부 수분에 대한 영향을 알아보기 위해 Corneometer를 이용하여 피부에 샴푸를 적용후 수분을 측정하였다. 5두의 건강한 개를 대상으로 7가지 샴푸로 Humilac, Sebocalm, Sebolytics, Etiderm, Benzoyl peroxide, HyLyt, Zn-7 Derm를 선정하여 적용하였다. Humilac의 경우 통계학적으로 유의한 피부수분의 증가는 적용 후 17분(p<0.05), 77분(p<0.01)에 나타났으며, Benzoyl peroxide의 경우 적용 후 77분(p<0.05)에 피부의 수분이 유의하게 감소되었다. 다른 샴푸의 경우 통계학적으로 유의하지 않았으나 전반적으로 감소하는 경향을 보였으며 적용 후 77분에 최초 적용 수치에 근접하게 감소하였다. 어떤 샴푸도 피부에 부작용을 유발하지 않았다. Corneometer는 실제 임상에서 피부의 수분을 평가하는데 간단하고 유용한 측정방법을 사료된다.