• Journal of Pharmaceutical Investigation
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• v.16 no.1
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• pp.18-23
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• 1986

Anemarrhenae Rhizoma has been clinically used as a sedative drug in oriental medicine. We observed the sedative action and effect on the movement of isolated-ileum with each water extract of Anemarrhenae Rhizoma (F-I), saline solution treated preparation (F-II) and 25% ethanol treated preparation (F-III). The results obtained were summerized as follows; 1) Sedative actions were recognized with F-I, F-II and F-III. 2) Prolonged effect of sleeping time was recognized significantly with F-I, F-II and F-III. 3) Each fraction of Anemarrhenae Rhizoma showed the released action on the isolated-ileum of the mouse, rat, rabbit and guinea pig, and antagonic action against contraction induced by acetylcholine, barium chloride and histamine. Thus the mechanism in the released action of the smooth muscle was partly considered as the direct dependence of the smooth muscle.

• Journal of the Korean Society of School Health
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• v.32 no.1
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• pp.1-9
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• 2019

Purpose: The purpose of this study was to identify the prevalence, subtypes and risk factors of Irritable Bowel Syndrome (IBS) among male adolescents. Methods: The survey was conducted on male adolescents (n=441) attending a high school. Rome IV criteria was used to diagnose IBS. Data on health promoting behaviors, psychological distress, sleep hygiene practices were collected using self-administered structured questionnaires. Results: The prevalence of IBS was 11.1% and the subtypes were mixed (77.5%), unclassified (10.2%), diarrhea-predominant (8.2%), and constipation-predominant (4.1%). Risk factors influencing IBS were sleeping time (Odds Ratio [OR]=1.00, 95% Confidence Interval [CI]: 0.99~1.00), anxiety, a subfactor under psychological distress (OR=1.12, 95% CI: 1.02~1.22), and arousal-related behaviors, a subfactor under sleep hygiene practices (OR=1.10, 95% CI: 1.03~1.17). Conclusion: Our findings indicated that IBS is a common problem in male adolescents. It is necessary to develop school-based intervention strategies addressing sleeping time, anxiety and arousal-related behaviors in order to prevent and improve IBS in male adolescents.

• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.152-158
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• 2022

Objective: This study addresses a case of fibromyalgia with insomnia and dry mouth. Methods: A patient diagnosed with fibromyalgia was treated with Korean medicine including herbal therapy with Guibiondam-tang-gagam, acupuncture, pharmacopuncture, moxibustion, and chuna for 16 days. To evaluate the therapeutic effects, sleeping hours, time taken to fall asleep, and surprise on waking were assessed, and a numeric rating scale (NRS) was used to monitor dry mouth. Results: After treatment, the patient's sleeping hours increased, time taken to fall asleep decreased, and the patient woke up surprised less often. The NRS score for dry mouth also decreased. Conclusion: These results suggest that Korean medicine therapies with Guibiondam-tang-gagam have a beneficial effect on insomnia and dry mouth as additional symptoms of fibromyalgia.

• Journal of Digital Convergence
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• v.12 no.2
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• pp.353-361
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• 2014

This study was conducted in order to identify the present condition of caffeinated drinks intake including energy drink. Concretely, It was investigated about stress degree, study attitude, sleeping hours by intake degree of caffeinated drinks. Descriptive survey research was designed. A total of 371 students in M university was participated. Data were collected through a questionnaire (from October 22, 2012. to October 26, 2012). The data were analyzed by t-test, ANOVA, scheffe's test, using the SPSS version 17.0. There were no significant differences between caffeinated drinks intake's degree including energy drink. Most of students thought caffeinated drinks intake have an effect on their health. Intake time of caffeinated drinks was before or after studying or sleepy. Caffeinated drinks intaked mostly alone. Intake causes of canned coffee or energy drink was sleepy and coffee mix, black coffee, coffee flavored milk and green tea was good taste. Stress degree, study attitude, sleeping hours by intake degree of caffeinated drinks were no significant effects between canned coffee, coffee mix, black coffee, green tea and energy drink. But, stress degree by intake degree of coffee flavored milk was significant low when it intakes more than once a day, sleeping hours was significant long when it was nondrinking.

• YAKHAK HOEJI
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• v.27 no.2
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• pp.163-168
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• 1983

The effect of ginseng butanol fraction (total sponin) on the absorption rate of ethanol in rat intestine was examined. Ginseng butanol fraction showed inhibitory effect on the intestinal absorption of ethanol in situ as well as in vitro test. Ginseng butanol fraction markedly decreased the ethanol blood level, delayed onset time of ethanol effect and shortened sleeping time when it was adminstered orally together with ethanol. These results suggest that ginseng may alter the ethanol blood level by decreasing the intestinal absorption of ethanol.

• Journal of Information Processing Systems
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• v.6 no.3
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• pp.413-434
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• 2010

Wireless sensor networks are usually characterized by dense deployment of energy constrained nodes. Due to the usage of a large number of sensor nodes in uncontrolled hostile or harsh environments, node failure is a common event in these systems. Another common reason for node failure is the exhaustion of their energy resources and node inactivation. Such failures can have adverse effects on the quality of the real-time services in Wireless Sensor Networks (WSNs). To avoid such degradations, it is necessary that the failures be recovered in a proper manner to sustain network operation. In this paper we present a dynamic Energy efficient Real-Time Job Allocation (ERTJA) algorithm for handling node failures in a cluster of sensor nodes with the consideration of communication energy and time overheads besides the nodes' characteristics. ERTJA relies on the computation power of cluster members for handling a node failure. It also tries to minimize the energy consumption of the cluster by minimum activation of the sleeping nodes. The resulting system can then guarantee the Quality of Service (QoS) of the cluster application. Further, when the number of sleeping nodes is limited, the proposed algorithm uses the idle times of the active nodes to engage a graceful QoS degradation in the cluster. Simulation results show significant performance improvements of ERTJA in terms of the energy conservation and the probability of meeting deadlines compared with the other studied algorithms.

• Biomolecules & Therapeutics
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• v.7 no.3
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• pp.271-277
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• 1999

Safety evaluation of LB71350, a new HIV-1 protease inhibitor, was performed in mice, rats and dogs. For the general behavior of mice, LB71350 at an oral dose of 200 mg/kg did not show any significant effects on muscle tone and locomotor activity. In terms of central nervous system, at oral doses of 200 mg/kg and 1000 mg/kg, LB71350 inhibited acetic acid-induced pain response approximately 41% and 83% of control. respectively. At oral doses of 200 mg/kg and 500 mg/kg, it reduced the rectal body temperature in rats. Pentylenetetrazole-induced seizure in mice was slightly potentiated by oral administration of LB71350 at doses ranging from 200 mg/kg to 1000 mg/Ag. Single or five day treatment of LB71350 doubled the hexobarbital- induced sleeping time in mice at oral doses ranging from 50 mg/kg to 500 mg/kg. It did not cause any effects on gastric secretion and acidity in rat at oral doses of 200 mg/kg and 1000 mg/kg and also it did not change intestinal motility in mice up to 1000 mg/kg. Blood coagulation indices such as prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin time (TT) in rats were not affected by the treatment of LB71350 up to 500 mg/kg. LB71350 caused no significant effects on the cardiac output, stroke volume, heart rate, and mean blood pressure when infused intravenously to the anesthetized rats and dogs. Taken together, LB71350 at high oral doses caused significant pharmacological effects on the central nervous system and the hexobarbital-induced sleeping time.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.1 no.1
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• pp.77-97
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• 1994

The circadian system represents a temporal order which is mediated by the mutual coupling of oscillators and by the synchronizing effects of zeitgebers. It is known that well-being of man depends partly on the maintenance of this order, and that repeated or long lasting disturbances to it such as shift work will Cause harmful effects. This study was a quasi-experimental study to test the effect of shift directions for the clinical nurses on the circadian rhythm. Fourteen nurses working at the general units of Y hospital were selected according to the established criteria. Fourteen subjects were assigned to a weekly shift but the directions of shift work were phase delay first and then phase advance or vice versa. Oral temperature, total sleeping time, frequency of sleep-wake cycle, fatigue, mental performance, and physical symptom were measured during these days except holidays. The data collection period was from April 26, 1993 to July 3, 1993. MANOVA and Wilcoxon signed rank test were used for statistical analysis. The results are summarized as follows. 1. Having worked on evening and night shifts in either phase delay or phase advance schedules, temperature rhythms of shift workers were gradually adapted to the new sleep-wake cycles. A complete adaptation to work on the night shift was achieved the sixth day of the night shift in the phase delay schedule compared to the partial adaptation to the work on the night shift in the phase advance schedule. Accordingly, by putting evening shift between day and night shifts, it will be possible for circadian rhythm to adapt easily to the night shift. 2. There were differences in the total sleeping time, frequency of steep-wake cycle, fatigue, and physical symptom except for mental performance between night shift and day, evening shift. This indicates further that shift workers working on the night shift have a hard time adapting to the shift work compared to the other shifts. 3. Evaluating all the acrophases of temperature rhythm either in phase delay or phase ad-vance schedules, it was shown that night to evening shift in the phase ad-vance schedule revealed the smallest phase move. Also phase advance schedule showed poorer adaptation to shift work than phase delay schedule in connection with total sleeping time, frequency of sleep-wake cycle, fatigue, mental performance, and physical symptom. It is suggested, taken together, these findings reflect that phase delay schedule facilitated the degree of adjustment to the shift work compared to the phase advance schedule.

• Journal of Digital Convergence
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• v.14 no.7
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• pp.225-232
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• 2016

This paper aimed to study on the relevance of mental health and oral health. The subjects were recruited total 3,261 elderly of over 40 years old, using the Sixth Korea National Health and Nutrition Examination Survey(KNHANES). All the collected data were analyzed by chi-square test, t-test, and logistic regression using SPSS 23.0 version. Logistic regression was used to analyze the relationship of sleeping time or stress and the number of remaining teeth, and 95% confidence intervals were computed. Sleeping time odds ratio(OR) of the number of remaining teeth was 1.52 (95% confidence interval: 1.074-2.135) and Stress odds ratio(OR) was 2.39 (95% confidence interval: 1.855-3.090), but there is no statistically significant difference after adjusted age, gender and other variables.

• Journal of Korean Academy of Nursing
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• v.49 no.2
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• pp.137-148
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• 2019

Purpose: This study aimed to investigate the effects of a reinforcement program for behavioral skills in postpartum care for couples with their first baby. Methods: The study used a non-equivalent control group and pretest-posttest design. It was conducted from January 14 to April 10, 2016 at a postpartum care center in D city. It analyzed 43 couples (22 in the experimental group and 21 in the control group.) For data analysis, descriptive statistics, test of homogeneity in pretest, independent t-tests, and repeated measures ANOVA were used. Results: For maternal fulfillment of postpartum care and postpartum fatigue, there was no significant difference in the interaction between group and time. In terms of parent-newborns attachment, the interaction between group and time showed a significant difference for mothers (F=13.63, p=.001) and fathers (F=6.51, p=.001). In marital intimacy, the interaction between group and time showed a significant difference for mothers (F=14.40, p<.001) and fathers (F=9.46, p=.004). In parenting stress, the interaction between group and time showed a significant difference for mothers (F=31.8, p<.001) and fathers (F=11.69, p=.001). A significant difference was found for the mothers' postpartum sleeping hours (F=0.14 p=.004). Conclusion: This program for behavioral skills in postpartum care, which is based on the information-motivation-behavioral skills model, improves postpartum care, parent-newborn attachment, marital intimacy, parenting stress, and maternal postpartum sleeping, by reinforcing behavioral skills required for postpartum care.