• Applied Microscopy
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• v.40 no.4
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• pp.185-191
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• 2010

Short peptides are potentially effective materials as cosmeceuticals, but their delivery across the skin can be problematic due to the ionic nature of peptides and the structure of the skin. For short peptide to be utilized as cosmeceuticals, its ability to penetrate the skin must be altered. In this study, we conjugated the widely used procollagen type I signal peptide, KTTKS, with oleic acid to improve the lipophilic properties of the peptide, and used the oleic acid-conjugated peptides to construct cosmeceutical nanosomes. Then we examined the penetration of cosmeceutical nanosomes prepared from isotope-labeled peptide into the skin after transdermal application using autoradiography. Because of its hydrophilic property of penta-peptide, the penta-peptide itself was not able to be penetrated through the stratum corneum of the skin. In contrast, nanosomes made from olecic acid conjugated penta-peptide were able to be penetrated through the stratum corneum effectively. Autoradiography showed the precise penetration points to dermal layer, demonstrating the appropriateness of this method for clarifying the mechanism of penetration of transdermal delivery systems.

• Korean Journal of Human Ecology
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• v.17 no.1
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• pp.171-179
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• 2008

This study focuses on 130 estheticians currently working in and around Daegu and Gyeongbuk region, in order to find out the current state of affairs and side effects related to aromatherapy. This paper is based on a survey. SPSS win 11.0 program was used for the analysis of descriptive statistics and independent t-test. According to the result of analysis, about 33% of the estheticians have had allergy experience. And in terms of installation of an air ventilation fan, which is the most important facility in an treatment room, more than half (50.8%) replied they did not have one. There was a statistically significant difference between those estheticians suffering from allergy and those who did not, in symptoms of stuffy nose/rhinitis (P<0.01) and dry skin/itchiness (P<0.5). (Allergy symptoms from the 33% of estheticians were limited to those which occurred after he or she began career) On work related symptoms, those who had work history at hospitals/clinics or apothecaries were compared. A statistically relevant difference was confirmed between those estheticians with therapy experience and those who had none, in all symptoms except headaches and drowsiness/weariness. In other words, there was difference in symptoms such as dryness of skin/itchiness (P<0.01), stuffy nose/rhinitis, dry throat, tension/nervousness, dizziness, tired eyes(P<0.5), nausea, having trouble with focusing, and fatigue(P<0.1). Those estheticians who had a history of treatment especially suffered most from dryness of skin and itchiness. The rate of regular check-ups and the use of masks, employed for self protection, was lower than average (amounting to 5 points), with the use of masks especially having the lowest average (1.7) points.

• Journal of the East Asian Society of Dietary Life
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• v.16 no.1
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• pp.1-12
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• 2006

This study examine the relationship between the intake of food conformable to each Sasang constitution and the recognition of irregular symptoms of health condition. The study subjects were 362 university students nationwide, classified by heir Sasang constitution. In terms of the intakes of conformable food and the symptom recognition, the number of multiple subjective symptoms tended to rise as the Soeum type digested the conformable food. As for the kinds of food, the Soyang type showed a significant positive correlation between the intake of cucumber namul and the symptoms of eyes and skin, but a negative correlation between the intake of Chongak Kimchi and the symptoms of the digestive system The Soeum type showed a significant positive correlation between multiple subjective symptoms and the intake of Gatkimchi, fernbrake namul, naeng-i soup, naeng-i namul, Korean leek Kimchi, crown daisy namul, and curled mallow soup, a significant positive correlation between the symptom recognition of the respiratory system and the intake of fried flatfish, and chicken gomtang but a negative correlation between the symptom recognition of the eye and skin and the intake of boiled eel. The Taeum type presented the a sigmificant positive correlation between multiple subjective symptoms and the intake of spaghetti, a positive correlation between the symptoms of the respiratory system and the intake of tuna salad, a positive correlation between the symptoms of the eye and skin and the intake of mafa tofu, spaghetti, and tuna salad, a negative correlation between the symptoms of the mouth and anus and the intake of codfish jiri, and a negative correlation between the symptoms of the respiratory system and the intake of tuna salad.

• Biomedical Science Letters
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• v.9 no.2
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• pp.75-84
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• 2003

To evaluate the influence of hepatic oxygen free radical systems on liver injury by topical p-phenylenediamine (PPD) application on rat skin, PPD (25 mg/16.5 $\textrm{cm}^2$) was topically applied to the abdominal region 5 times every other day and sacrificed. By PPD treatment, increasing rate of liver weight/body weight (%), serum activities of alanine aminotransferase and aspartate aminotransferase and decreasing rate of microsomal glucose-6-phosphatase activity were higher in the rats fed tungstate supplemented diet than those fed a standard diet. These findings indicate that group fed tungstate supplemented diet have more severe liver injury compared with group fed standard diet on topical PPD application. However, the activities of oxygen free radical generating enzymes such as xanthine oxidase (XO) and cytochrome P450 dependent aniline hydroxylase and those of oxygen free radical scavenging enzymes were not found to be different between these two animal groups. In the present study, a novel monitoring method to detect the generating of oxygen free radicals in liver extract was devised. Throughout this method, the oxidized PPD produced by oxygen free radicals was determined colorimetrically. The increasing rate of PPD oxidation by liver homogenate was higher in tungstate fed animals than in standard diet fed ones. Among the fractionations of liver extract, the mitochondrial and postmitochondrial fractions in the liver extract of tungstate fed animals led to a higher availability of PPD oxidation by PPD treatment compared with standard diet fed ones. In conclusion, these results suggest that an enhanced liver injury in tungstate fed animals treated with PPD may be due to oxygen free radicals produced in other systems except oxygen free radicals generating from cytosolic XO system. Especially, oxidative availability by PPD can be used for oxygen free radical detection in some tissue.

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.1 s.160
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• pp.119-130
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• 2007

The objects of this study were to investigate responses and peculiarity during local cooling by parts of the human body and to show permissible safety limits without injurious to his health because of excessive cooling when he works hot environments. It were measured rectal temperature, skin temperature, heart rate, total body weight loss, local sweat in back and thigh, clothing microclimate and subjective sensation on 8 subjects and cooling parts were head, neck, chest, abdomen, back, waist, hip, upper arm, forearm, hand, thigh, calf and foot. According to above-mentioned the first experiment, we chose permissible safety limits by parts of the human body for one hour. In the second experiment, it was showed permissible safety limits by parts which examined their safety about health through 4 hours cooling test on 3 subjects. The results are as follows: 1. As a result of the first experiment, we chose permissible safety limits by parts, as follows, head $25^{\circ}C$, neck $20^{\circ}C$, chest $27^{\circ}C$, abdomen $25^{\circ}C$, back $20^{\circ}C$, waist $20^{\circ}C$, upper arm $20^{\circ}C$, forearm $20^{\circ}C$, hand $23^{\circ}C$, thigh $20^{\circ}C$, calf $20^{\circ}C$ and foot $23^{\circ}C$ in $37^{\circ}C$, 50%R.H. environment for 1 hour. 2. As a result of the second experiment, cooling on these safety limits temperatures except chest didn't have a bad effect on health. So it was proved that right permissible safety limits of chest was $28^{\circ}C$. From these results, it has been suggested that skin temperature didn't fall below permissible safety limits when human body was to be cool by parts.

• Safety and Health at Work
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• v.12 no.2
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• pp.244-248
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• 2021

Background: Sunburn is the main avoidable cause of skin cancer. Beach lifeguards spend many hours exposed to the effects of solar radiation during their work day, precisely at times of the year when levels of solar irradiation are highest. The aim of this study is to quantify the risk to beach lifeguards of sun exposure. Methods: A descriptive cross-sectional study was carried out in the Western Costa del Sol, southern Spain, during the summer of 2018. The research subjects were recruited during a skin cancer prevention course for beach lifeguards. All participants were invited to complete a questionnaire on their habits, attitudes, and knowledge related to sun exposure. In addition, ten were specially monitored using personal dosimeters for three consecutive days, and the results were recorded in a photoprotection diary. A descriptive analysis (mean and standard deviation for the quantitative variables) was performed, and inter-group differences were evaluated using the Mann-Whitney U test. Results: Two hundred fifteen lifeguards completed the questionnaire, and 109 met the criteria for inclusion in this analysis. The mean age was 23.8 years (SD: 5.1), 78.0% were male, 71.5% were phototype III or IV (Fitzpatrick's phototype), and 77.1% had experienced at least one painful sunburn during the previous summer. The mean daily personal ultraviolet exposure per day, the minimal erythema dose, and the standard erythema dose, in J/m², were 634.7 [standard deviation (SD): 356.2], 2.5 (SD: 1.4) and 6.35 (SD: 3.6), respectively. Conclusion: Beach lifeguards receive very high doses of solar radiation during the work day and experience correspondingly high rates of sunburn. Intervention strategies to modify their sun exposure behavior and working environment are necessary to reduce the risk of skin cancer for these workers and to promote early diagnosis of the disease.

• Journal of the Korean Home Economics Association
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• v.44 no.11
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• pp.43-50
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• 2006

The purpose of this study is to analyze the use and satisfaction on cosmetics of middle- and old-aged women with well-being pursuit disposition. A survey was conducted from January 20 to February 10 in 2006. The statistical analysis methods used to analyze the 393 middle- and old- aged female subjects were frequency analysis, reliability analysis, factor analysis, cluster analysis, crosstab, and multiple regression analysis. First, middle- and old-aged women were using functional cosmetics for wrinkle and whitening as well as skin lotion, moisture lotion and nutritive cream. They applied basic skin make-up only or partial make-up on the eyes and lips. Second, the well-being pursuit disposition factors were determined to be eco-friendly pursuit disposition, economical pursuit disposition, and health pursuit disposition. The well-being pursuit disposition factors had an effect on satisfaction of basic cosmetics. While the economical pursuit disposition factor had an effect on satisfaction of colored cosmetics. Third, the clusters from well-being pursuit disposition were determined to be wellbeing unconcerned group, eco-friendly concerned group, economical concerned group, and health concerned group. The proportion of subjects applying basic and colored cosmetics was high in health concerned group.

• Korean Journal of Occupational Health Nursing
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• v.29 no.3
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• pp.192-201
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• 2020

Purpose: This study aims to conduct an integrated literature review of infection control studies conducted by nursing care workers in long-term care facilities in Korea. Methods: Through the domestic search engines RISS and KISS, seven articles were selected by searching for theses and academic journals published in Korea from 2008 to January 2020. Results: In total, six research studies and one intervention study out of seven studies were analyzed. Measurement tools for examining the knowledge and performance of infection-related care workers consisted of skin infection, aspiration pneumonia, urinary tract infection, and hand hygiene. Factors affecting nursing care workers' infection management performance were infection management knowledge, education level, health status, and importance awareness. Conclusion: This study showed it is necessary to develop a tool that can accurately measure nursing care workers' infection management knowledge and performance. In addition, it is necessary to develop an intervention program for nursing care workers' infection control.

• Journal of environmental and Sanitary engineering
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• v.22 no.4
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• pp.45-54
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• 2007

With the rapid development of economy, scientific technology, and medical technology, as the current society is also changing competitively, we are compelled to have many psychological and problems such as pressure, mental stress and tension as well as physical problems. Therefore, the more current industries develops, the more attention is given to health in preventive level rather than treatment level. Contemporary people have paid more attention to management of health and have a desire for beautiful and healthy life. In other words, their interest in consistent management of their health and beauty are getting stronger. To satisfy the desire to live healthily and beautifully, many natural therapies that can be applied for actual living have been developed, which the public are willing to accept. Therefore, this study is to specifically demonstrate the followings through interviews with the customers who have armoatherapy: What effect customers' knowledge on aromatherapy, frequency of use, expenses, experiences of side-effects, and perception on its effect on skin care will have on customer satisfaction and intention to reuse the service. The results are presented as follows: Though customers' perception on aroma is high, they usually use it only on their faces. So is should be promoted in various ways. It is demonstrated that customers' satisfaction has a significant effect on their intention to reuse it.

• Journal of Haehwa Medicine
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• v.12 no.1
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• pp.147-168
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• 2003

This study is about the relationship between the effect of Radiating Qui Therapy on human body and the resulting subjective qui sensation. Patients were between 30 and 50 years of age. n=21 persons received DITI (n=14 patients were provided, n=9 control group) twice examination with Radiating Qui Therapy. First all patients were examined by DITI. After treatment with Radiating Qui Therapy (n=14) both the treated and the control groups were eaxmined again. Radiating Qui Therapy is provided upright position. After Radiating Qui Therapy 92% of the treated group felt a significant qui sensation and 43.5 % felt a warmth at the abdomen and over the whole body. A data of this study show Radiating Qui Therapy has s stimulating effect on human skin temperature. As disease region and Qui sensation are very closely related to each other results strongly suggest that Radiating Qui Therapy could be used as a treatment for a several disease.