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CMI Tolerant Readout IC for Two-Electrode ECG Recording (공통-모드 간섭 (CMI)에 강인한 2-전극 기반 심전도 계측 회로)

  • Sanggyun Kang;Kyeongsik Nam;Hyoungho Ko
    • Journal of Sensor Science and Technology
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    • v.32 no.6
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    • pp.432-440
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    • 2023
  • This study introduces an efficient readout circuit designed for two-electrode electrocardiogram (ECG) recording, characterized by its low-noise and low-power consumption attributes. Unlike its three-electrode counterpart, the two-electrode ECG is susceptible to common-mode interference (CMI), causing signal distortion. To counter this, the proposed circuit integrates a common-mode charge pump (CMCP) with a window comparator, allowing for a CMI tolerance of up to 20 VPP. The CMCP design prevents the activation of electrostatic discharge (ESD) diodes and becomes operational only when CMI surpasses the predetermined range set by the window comparator. This ensures power efficiency and minimizes intermodulation distortion (IMD) arising from switching noise. To maintain ECG signal accuracy, the circuit employs a chopper-stabilized instrumentation amplifier (IA) for low-noise attributes, and to achieve high input impedance, it incorporates a floating high-pass filter (HPF) and a current-feedback instrumentation amplifier (CFIA). This comprehensive design integrates various components, including a QRS peak detector and serial peripheral interface (SPI), into a single 0.18-㎛ CMOS chip occupying 0.54 mm2. Experimental evaluations showed a 0.59 µVRMS noise level within a 1-100 Hz bandwidth and a power draw of 23.83 µW at 1.8 V.

Endovascular embolization of persistent liver injuries not responding to conservative management: a narrative review

  • Simon Roh
    • Journal of Trauma and Injury
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    • v.36 no.3
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    • pp.165-171
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    • 2023
  • Trauma remains a significant healthcare burden, causing over five million yearly fatalities. Notably, the liver is a frequently injured solid organ in abdominal trauma, especially in patients under 40 years. It becomes even more critical given that uncontrolled hemorrhage linked to liver trauma can have mortality rates ranging from 10% to 50%. Liver injuries, mainly resulting from blunt trauma such as motor vehicle accidents, are traditionally classified using the American Association for the Surgery of Trauma grading scale. However, recent developments have introduced the World Society of Emergency Surgery classification, which considers the patient's physiological status. The diagnostic approach often involves multiphase computed tomography (CT). Still, newer methods like split-bolus single-pass CT and contrast-enhanced ultrasound (CEUS) aim to reduce radiation exposure. Concerning management, nonoperative strategies have emerged as the gold standard, especially for hemodynamically stable patients. Incorporating angiography with embolization has also been beneficial, with success rates reported between 80% and 97%. However, it is essential to identify the specific source of bleeding for effective embolization. Given the severity of liver trauma and its potential complications, innovations in diagnostic and therapeutic approaches have been pivotal. While CT remains a primary diagnostic tool, methods like CEUS offer safer alternatives. Moreover, nonoperative management, especially when combined with angiography and embolization, has demonstrated notable success. Still, the healthcare community must remain vigilant to complications and continuously seek improvements in trauma care.

Analysis of Global Trends in the Cross-border Transfer of Personal Data and Its Implications for Korea (개인정보 국외이전 관련 규범 국제 동향 분석 및 한국에의 시사점)

  • Bomin-Ko
    • Korea Trade Review
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    • v.46 no.6
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    • pp.239-255
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    • 2021
  • To review the theoretical background of regulatory approaches to cross-border transfer of personal data, this paper divides major digital trade participating countries into four types according to the OECD - non-regulatory, post-intervention, pre-supervision, and national control. It then analyzes the US, Japan, the EU, and China respectively that belong to each type. South Korea, which is currently about to pass the amendment by the National Assembly, has identified that it is in the middle of post-intervention and pre-supervision, and needs to evolve into pre-supervision norms like the EU while it has to participate more actively in the process of establishing international digital trade rules. Korea first needs to sign digital trade agreements and promote mutual certification projects more actively from the standpoint of a medium-sized open country with growing digital companies and digitally-open consumers. Second, the government should fully consider the interests of not only companies but also various trade stakeholders including domestic consumers, when drafting and implementing trade policies. To this end, 'a single window approach' is needed not only at the Ministry of Trade, Industry, and Energy, but also at the level of the entire government which require an integrated form of digital trade policy governance.

Electronically tunable compact inductance simulator with experimental verification

  • Kapil Bhardwaj;Mayank Srivastava;Anand Kumar;Ramendra Singh;Worapong Tangsrirat
    • ETRI Journal
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    • v.46 no.3
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    • pp.550-563
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    • 2024
  • A novel inductance simulation circuit employing only two dual-output voltage-differencing buffered amplifiers (DO-VDBAs) and a single capacitance (grounded) is proposed in this paper. The reported configuration is a purely resistor-less realization that provides electronically controllable realized inductance through biasing quantities of DO-VDBAs and does not rely on any constraints related to matched values of parameters. This structure exhibits excellent behavior under the influence of tracking errors in DO-VDBAs and does not exhibit instability at high frequencies. The simple and compact metal-oxide semiconductor (MOS) implementation of the DO-VDBAs (eight MOS per DO-VDBA) and adoption of grounded capacitance make the proposed circuit suitable for on-chip realization from the perspective of chip area consumption. The function of the pure grounded inductance is validated through high pass/bandpass filtering applications. To test the proposed design, simulations were performed in the PSPICE environment. Experimental validation was also conducted using the integrated circuit CA3080 and operational amplifier LF-356.

Ulnar artery access for intracranial mechanical thrombectomy procedure: A salvage option after failed trans-femoral and trans-radial access

  • Muhammad U Manzoor;Abdullah A Alrashed;Ibrahim A Almulhim;Sultan Alqahtani;Fahmi Al Senani
    • Journal of Cerebrovascular and Endovascular Neurosurgery
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    • v.25 no.4
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    • pp.429-433
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    • 2023
  • 84 years old gentle man with past medical history of hypertension and diabetes presented with sudden onset right sided weakness and aphasia for two hours. Initial neurological assessment revealed National Institute of Health Stroke Scale (NIHSS) 17. Computed tomography (CT) scan demonstrated minimal early ischemic changes along left insular cortex with occlusion of left middle cerebral artery (MCA). Based on clinical and imaging findings, decision was made to perform mechanical thrombectomy procedure. Initially, right common femoral artery approach was utilized. However, due to unfavorable type-III bovine arch, left internal carotid artery could not be engaged via this approach. Subsequently, access was switched to right radial artery. Angiogram revealed small caliber radial artery, with larger caliber ulnar artery. Attempt was made to advance the guide catheter through the radial artery, however significant vasospasm was encountered. Subsequently, ulnar artery was accessed and successful thrombolysis in cerebral infarction (TICI) III left MCA reperfusion was achieved with a single pass of mechanical thrombectomy via this approach. Post procedure neurological examination demonstrated significant clinical improvement. Doppler ultrasound 48 hours after the procedure demonstrated patent flow in radial and ulnar arteries with no evidence of dissection.

Effects of Systemic and Focal Hypoxia on the Activities of Rostral Ventrolateral Medullary Neurons in Cats

  • Yan, Hai-Dun;Kim, Charn;Kim, Ji-Mok;Lim, Won-Il;Kim, Sang-Jeong;Kim, Jun
    • The Korean Journal of Physiology
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    • v.30 no.1
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    • pp.105-116
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    • 1996
  • Rendering the brain ischemic would evoke the cerebral ischemic reflex which is characterized by an arterial pressor response, apnea and bradycardia. Since the rostral ventrolateral medulla (RVLM) is known to play a key role in the maintenance of normal cardiopulmonary activity, during the cerebral ischemic reflex some cardiac related cells should be excited and respiration related cells inhibited. In this context, the responses of RVLM neurons to systemie and focal hypoxia were analyzed in the present study. Twenty-five adult cats of either sex were anesthetized with ${\alpha}-chloralose$ and the single neuronal activities were identified from RVLM area. For the induction of focal hypoxia in the recording site, sodium cyanide was applied iontophoretically and for systemic hypoxia the animal was ventilated with nitrogen gas for a twenty-second period. Cellular activities were analyzed in terms of their discharge pattern and responses to the hypoxia by using post-stimulus time and single-pass time histograms. Of eighteen cardiac related cells recorded from the RVLM area, twelve cells were excited by iontophoresed sodium cyanide and of twenty-five respiration related cells, fourteen cells were excited by iontophoresed sodium cyanide. Remaining cells were either inhibited or unaffected. Eight of fifteen cells tested with iontophoresed sodium lactate were excited and remaining seven cells were inhibited. Systemic hypoxia induced by nitrogen gas inhalation elevated the arterial blood pressure, but excited, inhibited or unaffected the single neuronal activities. Some cells showed initial excitation followed by inhibition during the systemic hypoxia. Bilateral vagotomy resulted in a decrease of arterial pressor response to the systemic hypoxia, and a slight decrease in the rhythmicity related to cardiac and/or respiratory rhythms. The single neuronal responses to either systemic or focal hypoxia were not affected qualitatively by vagotomy. From the above results, it was concluded that the majority of the cardiac- and respiration- related neurons in the rostral ventrolateral medulla be excited by hypoxia, not through the mediation of peripheral chemoreceptors, and along with the remaining inhibited cells, all these cells be involved in the mediation of cerebral ischemic reflex.

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The Effects of Trunk Stabilization Training on a Stroke Patient's Postural Control and Activities of Daily Living: A Sing Subject Design (뇌졸중 환자의 체간안정화 훈련이 자세조절과 일상생활동작에 미치는 영향: 단일사례연구)

  • Nam, Ju-Hyeon;Shim, Gyeong-Bo;Gwak, Seong-Won
    • The Journal of Korean society of community based occupational therapy
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    • v.4 no.1
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    • pp.75-84
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    • 2014
  • Objective : This study intends to suggest an effective clinical intervention method for stroke patients by applying a trunk stabilization training program to a single stroke patient and investigating and analyzing the effects of the program on postural control and activities of daily living. Methods : The subject of this study was a 75 year-old female stroke patient hospitalized in C Hospital located in Gyeongju, Gyeongsangbuk-do. As for the research design, A-B-A reversal design was used with a single subject design; and the research period was a total of five weeks from April 21, 2014 to May 23, 2014. As for the research process, a total of 15 sessions were carried out including three sessions of baseline(A), nine sessions of an intervention period(B), and three sessions of maintenance(A'); and the trunk stabilization program was applied during the intervention period. To evaluate the participant's postural control and activities of living life, the Postural Assessment Scale for Stroke(PASS) and the modified Barthel Index(MBI) were used. Visual analysis was used in which collected data were plotted on a graph, using Microsoft Office Excel 2013. Results : In the postural control test, the mean scores improved from 11.7 in the baseline phase to 14.8 in the intervention phase and 15.3 in the maintenance phase. In the evaluation of activities of daily living, the score improved from 66(medium dependence) during the baseline period to 80(low dependence) after intervention and at the maintenance phase. Conclusion : It was found that the trunk stabilization training program showed effects on the stroke patient's postural control or alignment, and furthermore a beneficial improvement in the patient's performing the activities of daily living, as well.

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Measurement of 18GHz Radio Propagation Characteristics in Subway Tunnel for Train-Wayside Multimedia Transmission (지하철 터널에서의 18GHz 무선영상신호 전파특성 측정)

  • Choi, Kyu-Hyoung;Seo, Myung-Sik
    • Journal of the Korean Society for Railway
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    • v.15 no.4
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    • pp.364-369
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    • 2012
  • This paper presents an experimental study on the radio propagation characteristics in subway tunnel at 18GHz frequency band which has been assigned to video transmission between train and wayside. The radio propagation tests are carried out in the subway tunnel of Seoul Metro using the antenna and communication devices of the prototype video transmission system. The measurement results show that 18GHz radio propagation in subway tunnel has smaller path loss than that of general outdoor radio environment. It is also cleared that the arch-type tunnels have smaller radio propagation losses than rectangular tunnels, and single track tunnels have smaller pass loss than double track tunnels. From the measurements, the radio propagation coverage is worked out as 520 meters. The curved tunnels which cannot have LOS communication between transmitter and receiver have large pass losses and fluctuation profile along distance. The radio propagation coverage along curved tunnels is worked out as 300 meters. These investigation results can be used to design the 18GHz radio transmission system for subway tunnel by providing the optimized wayside transmitter locations and handover algorithm customized to the radio propagation characteristics in subway tunnels.

Measurement of picosecond laser pulsewidth and pulseshape by two-photon fluorescence and noncolloinear type I second harmonic generation method (이광자 형광법과 비공선 일종 이차고조파법에 의한 피코초 레이저 펄스폭과 펄스형 측정)

  • 한기호;박종락;이재용;김현수;엄기영;변재오;공흥진
    • Korean Journal of Optics and Photonics
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    • v.7 no.3
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    • pp.251-259
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    • 1996
  • Two-Photon Fluorescence (TPF) experiment measures temporal width of an amplified short laser pulse which has passed through a four-pass Nd: glass amplifier, after selecting a single pulse from pulse train Q-switched and mode-locked(QSML) in Nd:YLF master oscillator. Determination of pulsewidth and pulseshape was also made with detection of autocorrelation trace of CW mode-locked pulse train by using noncollinear type I Second Harmonic Generation (SHG) method. The observed TPF track showed various patterns, depending on pulse-selecting position in QSML pulse train. That is, autocorrelation of a pulse extracted at front of the train displayed smooth pulse shape, while one from the trailing part of the train created many sharp spikes and substructure in the pulse. By TPF method, pulsewidth was measured to be 44.4 ps with contrast ratio of 2.86 which enabled us to find out energy fraction of a pulse to total energy, (sum of pulse and background); we obtain the value of 0.62. Pulsewidth of 46.6ps was also acquired in another SHG experiment with the help of only mode-locked pulse train. On the other hand, we confirmed that shape of the pulse is close to $sech^2$ one as a result of fitting the SHG autocorrelation signal with various functions. With simulation using this $sech^2$ type of pulse, pulsewidth reduction of the beam, having passed through four-pass amplifier, was also verified.

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An Implementation of Low Power MAC using Improvement of Multiply/Subtract Operation Method and PTL Circuit Design Methodology (승/감산 연산방법의 개선 및 PTL회로설계 기법을 이용한 저전력 MAC의 구현)

  • Sim, Gi-Hak;O, Ik-Gyun;Hong, Sang-Min;Yu, Beom-Seon;Lee, Gi-Yeong;Jo, Tae-Won
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.4
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    • pp.60-70
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    • 2000
  • An 8$\times$8+20-bit MAC is designed with low power design methodologies at each of the system design levels. At algorithm level, a new method for multipl $y_tract operation is proposed, and it saves the transistor counts over conventional methods in hardware realization. A new Booth selector circuit using NMOS pass-transistor logic is also proposed at circuit level. It is superior to other circuits designed by CMOS in power-delay-product. And at architecture level, we adopted an ELM adder that is known to be the most efficient in power consumption, operating frequency, area and design regularity as the final adder. For registers, dynamic CMOS single-edge triggered flip-flops are used because they need less transistors per bit. To increase the operating frequency 2-stage pipeline architecture is adopted, and fast 4:2 compressors are applied in Wallace tree block. As a simulation result, the designed MAC in 0.6${\mu}{\textrm}{m}$ 1-poly 3-metal CMOS process is operated at 200MHz, 3.3V and consumed 35㎽ of power in multiply operation, and operated at 100MHz consuming 29㎽ in MAC operations, respectively.ly.

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