• Journal of Yeungnam Medical Science
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• 제36권1호
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• pp.50-53
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• 2019

Awareness during general anesthesia occurs in approximately 0.1-0.2% of cases; nevertheless, particular attention is required because it can lead to critical complications including insomnia, depression, anxiety, and post-traumatic stress disorder. To prevent these complications, bispectral index (BIS) and end-tidal anesthetic gas (ETAG) concentration monitoring are commonly used to examine patient consciousness during surgery. In the present case, an 80-year-old man was scheduled for total gastrectomy. Anesthesia was maintained using desflurane 4.0-5.0% vol, oxygen, and nitrous oxide. The authors simultaneously monitored BIS, which was maintained between 37 and 43, and ETAG, which was maintained between 0.9 and 1.2 minimum alveolar concentration (MAC). After the operation, however, the authors were surprised to learn that the patient complained of awareness during anesthesia. Although BIS and ETAG concentration monitoring are useful in preventing awareness during anesthesia, they cannot be completely trusted. Even though BIS was maintained at approximately 40 and ETAG at 0.7-1.3 MAC, awareness during anesthesia occurred.

• 천문학회지
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• 제47권6호
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• pp.293-302
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• 2014

Simultaneous time monitoring observations of $H_2O$ $6_{16}-5_{23}$, SiO J = 1-0, 2-1, 3-2, and $^{29}SiO$ ${\upsilon}=0$, J = 1-0 lines are carried out in the direction of the Mira variable star TX Cam with the Korean VLBI Network single dish radio telescopes. For the first time, the $H_2O$ maser emission from TX Cam is detected near the stellar velocity at five epochs from April 10, 2013 (${\phi}=3.13$) to June 4, 2014 (${\phi}=3.89$) including minimum optical phases. The intensities of $H_2O$ masers are very weak compared to SiO masers. The variation of peak antenna temperature ratios among SiO ${\upsilon}=1$, J = 1-0, J = 2-1, and J = 3-2 masers is investigated according to their phases. The shift of peak velocities of $H_2O$ and SiO masers with respect to the stellar velocity is also investigated according to observed optical phases. The $H_2O$ maser emission occurs around the stellar velocity during our monitoring interval. On the other hand, the peak velocities of SiO masers show a spread compared to the stellar velocity. The peak velocities of SiO J = 2-1, and J = 3-2 masers show a smaller spread with respect to the stellar velocity than those of SiO J = 1-0 masers. These simultaneous observations of multi-frequencies will provide a good constraint for maser pumping models and a good probe for investigating the stellar atmosphere and envelope according to their different excitation conditions.

• 분석과학
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• 제23권4호
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• pp.405-413
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• 2010

축산물(소의 근육 및 간)중에 잔류하는 합성 글루코코티코이드 6종 (betamethasone, dexamethasone, prednisone, prednisolone, methylprednisolone, flumethasone)에 대한 동시분석방법을 확립하였다. 효과적인 기기분석을 위해서 시료는 C18 고체상 카트리지를 사용하여 에틸아세테이트 용매를 사용하여 추출/정제하였다. C18 컬럼을 사용하여 분리한 후 음이온 전기분무 질량분석법의 multiple reaction monitoring 방법을 사용하여 정량 및 정성 분석을 수행하였다. 효과적이고 감도있는 HPLC-MS/MS 분석을 위해서 0.1% 포름산이 포함된 물과 아세토나이트릴이 이동상 용매로 사용되었다. 메트릭스와 약물의 종류에 따라서 검출한계(LOD)는 $0.2-0.1\;{\mu}g$/kg, 정량한계(LOQ)는 $0.8-3.4{\mu}g$/kg 이었으며, 회수율은 89.5-119.6%이었다. 확립된 기존의 방법들에 비해 6종의 글루코코티코이드의 동시분석 방법이 간소화되었고, 좋은 정확도, 정밀도 및 회수율을 나타내었으며, 축산 육류 중에 잔류하는 글루코코티코이드들 분석하는데 사용될 수 있을 것이다.

• 한국환경농학회지
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• 제40권2호
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• pp.142-147
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• 2021

BACKGROUND: Agricultural use and pest control purposes of pesticides may lead to livestock products contamination. Thiodicarb and its degraded product, methomyl, are carbamate insecticides that protect soya bean, maize, fruit, and vegetables and control flies in animal and poultry farms. For maximum residue limit enforcement and monitoring, the JMPR residue definition of thiodicarb in animal products is the sum of thiodicarb and methomyl, expressed as methomyl. This residue definition was set to consider the fact that thiodicarb was readily degraded to methomyl in animal commodities. And therefore the simultaneous analytical method of thiodicarb and methomyl is required for monitoring in livestock products. METHODS AND RESULTS: The study was conducted using a quick, easy, cheap, effective, rugged, and safe (QuEChERS) method and HPLC-MS/MS to determine the thiodicarb and methomyl in livestock products. The limit of quantitation (LOQ) was 0.01 mg/kg for livestock products, including beef, pork, chicken, milk, and egg. The coefficient of determinations (r²) for the calibration curve were > 0.99, which was acceptable values for linearity. Average recoveries at spiked levels (LOQ, 10LOQ, and 50LOQ, n=5) in triplicate ranged from 73.2% to 102.1% and relative standard deviations (RSDs) were less than 10% in all matrices. CONCLUSION: The analytical method was validated for the performance parameters (specificity, linearity, accuracy, and precision) in livestock products to be acceptable by the CODEX guidelines.

• Mass Spectrometry Letters
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• 제13권3호
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• pp.58-83
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• 2022

We developed analytical methods using high performance chromatography (HPLC) and liquid chromatography tandem mass spectrometry (LC-MS/MS) for the simultaneous determination of 80 unapproved compounds in dietary supplements. The target compounds for analysis were unapproved ingredients (e.g., pharmaceuticals) that have potential adverse effects on consumers owing to accidental misuse, overuse, and interaction with other medication in dietary supplement. Two analytical methods were tested to identify the optimal validation results according to AOAC guideline. As a result, limit of quantification (LOQ) was 0.14-0.5 ㎍ mL^-1; linearity (r²) was ≥ 0.99; accuracy (expressed as recovery) was 78.9-114%; precision (relative standard deviation) was ≤ 4.28% in the HPLC method. In the LC-MS/MS method, LOQ was 0.01-2 ng mL^-1, linearity (r²) was ≥0.98, accuracy was 71.7-119%; precision was ≤ 12.5%. The developed methods were applied to 51 dietary supplements collected from 2019 to 2021 through MFDS alert system. Based on our previous monitoring study, major compounds were icariin, sibutramine, yohimbine, sildenafil, tadalafil, sennosides (A, B), cascarosides (A, B, C, D), and phenolphthalein. In this study, we re-analyzed samples of detected compounds, and evaluated the statistical difference using Bland-Altman analysis to compare two analytical approaches between HPLC and LC-MS/MS. These results showed a good agreement between two methods that can be used to monitor the unapproved ingredients in dietary supplements. The developed two methods are complementarily suitable for monitoring the adulteration of 80 unapproved compounds in dietary supplements.

• 천문학회보
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• 제46권2호
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• pp.49.1-49.1
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• 2021

We carried out simultaneous monitoring observations of five maser lines, H₂O (22 GHz), SiO 𝝊 =1, 2, J =1-0 (43.1, 42.8 GHz), and SiO 𝝊 =1, J=2-1, J =3-2 (86.2, 129.3 GHz), toward the Mira variable star WX Serpentis with the 21-m antennas of the Korean VLBI Network (KVN) in 2009-2021 (~12 years). Most spectra of the H₂O maser are well separated into two parts of two blue- and one redshifted features within ± 10 km s-1 of the stellar velocity. All detected SiO masers are generally concentrated within ± 5 km s-1 of the stellar velocity, and sometimes appear split into two components. Overall, the profiles of SiO and H₂O masers detected in WX Serpentis illustrate typical characteristics of the Mira variable. In addition, flux variations of both SiO and H₂O masers are well correlated with the optical light curve of the central star, showing a phase lag of ~ 0.1 for SiO masers and ~ 0.2 for H₂O maser. This phenomenon is considered to be the direct effect of propagating shock waves generated by the stellar pulsation, because SiO and H₂O masers are sequentially distributed at different positions with respect to the central star. In addition, we analyzed long-term trends and characteristics of maser velocities, maser ratio, and the velocity extents (the full width at zero power; FWZP). We also investigated a spectral energy distribution (SED) ranging from 1.2 to 240 ㎛ obtained using several infrared data: 2MASS, WISE, IRAS, ISO, COBE DIBRE, RAFGL, and AKARI (IRC and FIS). From the IRAS LRS and ISO SWS spectra of this star, we identified 9.7 and 12 ㎛ silicate emission features consistent with the SE6 spectrum model, corresponding to the typical AGB phase.

• 한국산학기술학회논문지
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• 제11권9호
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• pp.3161-3167
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• 2010

제어를 위한 기구부의 위치 정보는 BLDC 모터의 홀센서를 이용하여 정확한 위치 및 속도제어가 가능하도록 알고리즘을 구현하였으며, 실제 기구부의 방위각과 고도각에 대한 제어 정밀도를 측정한 결과 최대 $2.02^{\circ}$, $1.01^{\circ}$. 오차범위 $1.86^{\circ}$이내로 비교적 정확하였다. 태양광 발전 모니터링 시스템은 LCU를 중심으로 한 통합 모니터링 제어 시스템으로 모든 장비들은 1:N 방식으로 다중 동시접속이 가능하고, 원격지에서 시스템의 제어 및 현재 상태에 대한 실시간 감시가 가능하도록 개발하였다.

• 천문학회지
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• 제48권5호
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• pp.267-275
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• 2015

Simultaneous time monitoring observations of H₂O and SiO maser lines were performed toward the D-type symbiotic binary system V407 Cyg with the Korean VLBI Network single dish radio telescope. These monitoring observations were carried out from March 2, 2010 (optical phase ϕ = 0.0), 8 days before the nova outburst on March 10, 2010 to June 5, 2014 (ϕ = 2.13). Eight days before the nova outburst, we detected the SiO v = 1, 2, J = 1–0 maser lines which exhibited values of 0.51 K (∼ 6.70 Jy) and 0.71 K (∼ 9.30 Jy), respectively, while after the outburst we could not detect them on April 2 (ϕ = 0.04), May 5 (ϕ = 0.09), May 8 (ϕ = 0.09), or on June 5, 2010 (ϕ = 0.13) within the upper limits of our KVN observations. After restarting our monitoring observations, we detected SiO v = 2, J = 1–0 masers starting on October 20, 2011 (ϕ = 0.83) and detected SiO v = 1, J = 1–0 masers starting on December 22, 2011 (ϕ = 0.92). These results provide clear evidence of the interaction between the shock from the nova outburst and the SiO maser regions of the Mira envelope. The peak emission of SiO v = 1, 2, J = 1–0 masers always occurred at blueshifted velocities with respect to the stellar velocity except for that of SiO v = 1 at one epoch. These phenomena may be related to the redistribution of SiO maser regions after the outburst. The peak velocity variations of SiO masers associated with stellar pulsation phases show an increasing blueshifted trend during our monitoring interval after the outburst.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2001년도 춘계학술발표대회 논문집
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• pp.244-249
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• 2001

In this paper, we present the simultaneous measurement of the fabricaition strain and temperature during and after cure of unsymmetric composite laminate uising fiber optic sensors. Fiber Bragg grating/extrinsic Fabry-Perot interferometric (FBG/EFPl) hybrid sensors are used to measure those measurands. The characteristic matrix of sensor is analytically derived and measurements can be done without sensor calibration. A wavelength-swept fiber laser is utilized as a light source. FBG/EFPI sensors are embedded in a graphite/epoxy unsymmetric cross-ply composite laminate at different direction and different location. We perform the real time measurement of fabrication strains and temperatures at two points of the composite laminate during cure process in an autoclave. Also, the thermal strains and temperatures of the fabricated laminate are measured in thermal chamber. Through these experiments, we can provide a basis for the efficient smart processing of composite and know the thermal behavior of unsymmetric cross-ply composite laminate.

• Structural Engineering and Mechanics
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• 제59권6호
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• pp.1037-1054
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• 2016

Structural parameter evaluation and external force estimation are two important parts of structural health monitoring. But the structural parameter identification with limited input information is still a challenging problem. A new simultaneous identification method in time domain is proposed in this study to identify the structural parameters and evaluate the external force. Each sampling point in the time history of external force is taken as the unknowns in force evaluation. To reduce the number of unknowns for force evaluation the time domain measurements are divided into several windows. In each time window the structural excitation is decomposed by orthogonal polynomials. The time-variant excitation can be represented approximately by the linear combination of these orthogonal bases. Structural parameters and the coefficients of decomposition are added to the state variable to be identified. The extended Kalman filter (EKF) is augmented and selected as the mathematical tool for the implementation of state variable evaluation. The proposed method is validated numerically with simulation studies of a time-invariant linear structure, a hysteretic nonlinear structure and a time-variant linear shear frame, respectively. Results from the simulation studies indicate that the proposed method is capable of identifying the dynamic load and structural parameters fairly accurately. This method could also identify the time-variant and nonlinear structural parameter even with contaminated incomplete measurement.