• 한국해양바이오학회지
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• 제2권4호
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• pp.230-233
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• 2007

Protein tyrosine phosphatase 1B (PTP1B) acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes. As part of our searching for PTP1B inhibitors from natural products, the extracts of marine microorganisms were screened for the inhibitory effects on the activity of protein tyrosine phosphatase 1B (PTP1B). Among the tested 304 extracts, 29 extracts exhibited inhibition rate ranging 40.1 - 83.6 % against PTP1B at the concentration level of $30{\mu}g/mL$.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 추계학술대회
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• pp.386-388
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• 2018

본 논문은 사회적 상호작용 결여로 감정 기복이 심하고 스트레스로 인해 정서불안 증세를 보이는 자폐 범주성 장애아동의 감정 상태를 인식하기 위한 목적으로 4가지 감정 자극에 대하여 생체신호를 분석하고 K-Means 알고리즘을 적용하여 획득한 정보로부터 감정 상태를 인식하는 방법을 제안한다. 실험구성은 참가자가 주어지는 감정자극 영상을 시청하는 동안 맥파 및 피부전도 센서를 이용하여 생체신호를 측정한 후 자율신경 비율을 나타내는 LF/HF의 심박 정보와 피부 반응 정보를 정량적으로 분석하였고, 추출된 정보로부터 K-Means 알고리즘을 적용하여 감정 상태를 분류하는 과정으로 진행된다. 총 3명의 일반인을 대상으로 실험을 진행하였으며, 4가지 감정 자극에 대한 실험을 수행한 결과, 생체신호 측정을 이용한 감정인식 방법이 제시되는 감정 자극을 충분히 분류할 수 있음을 확인할 수 있었다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2005년도 추계종합학술대회
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• pp.1132-1134
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• 2005

현재의 병원 전산 시스템은 각 병원의 자체 전산화 구축으로 인하여 각 개인의 진료기록 및 처방전 등 개인의 신상 자료가 한 병원에 국한되어 있고 타 병원 및 공공기관에서의 진료기록 필요시 진단서를 발급해야 하는 불편함이 초래하고 있다. 이에 본 논문에서는 개인의 신상 기록 및 진료기록 통합 시스템을 제안한다. 제안된 방법은 통합데이터베이스 서버를 구축하고 각 병원 및 약국에서는 전용선을 통하여 접속함으로서 개인의 진료기록 및 처방전을 각 병원과 약국에서 공유할수 있게 되어 병원관리의 투명성과 신뢰성이 제고된다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 추계학술대회
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• pp.93-95
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• 2016

본 논문에서는 초음파 영상에서 결절종을 추출하는 방법을 제안한다. 명암 대비가 낮은 초음파 영상에서도 정확히 추출하기 위해 퍼지 스트레칭 기법을 개선하여 명암 대비를 강조한 후에 ROI 영역을 추출한 후, 추출된 ROI 영역에 대해 FCM 알고리즘을 적용하여 양자화 한다. 양자화된 ROI 영역에서 8방향 윤곽선 추적 알고리즘을 적용하여 결절종의 후보 영역을 추출한다. 추출된 결절종의 후보 영역 중에서 면적이 가장 크거나 타원 형태를 가진 영역을 라벨링 기법을 적용하여 최종적으로 결절종 영역을 추출한다. 제안된 방법을 결절종 초음파 영상을 대상으로 실험한 결과, 기존의 결절종 추출 방법보다 제안된 방법이 결절종 영역이 비교적 정확히 추출되는 것을 실험을 통하여 확인하였다.

• 건축역사연구
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• 제30권1호
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• pp.7-17
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• 2021

Bang walls surround the four sides of Band in ancient capital cities of East Asia where the Bang system was in operation. There are ongoing research efforts for the structure of a capital city and Bang system around the capital of Silla, but there is a huge shortage of research on Bang walls. This study thus set out to examine Bang walls in the capital of Silla around the Hwangnyongsa Temple and its surroundings. The findings show that the Bang walls in the capital of Silla were built with a mix of earth and stone and with tiled roofs on top. The sizes of Bang walls were distinguished from the walls of individual structure groups inside Bang and closely related to the Bang size and the width of adjacent roads.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.255.1-255.1
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• 2002

We investigated the anti-proliferative effects of lxeris sonchifolia H. (godulbaegi) root extracts. luteolin(3'. 4', 5. 7-Q-glucoside and 3'. 4', 5, 7-tetrahydoxyflavone) and apigenin (3', 4'. 5. 7-O-gluconic acid) on HepG2 (p53 wild type) cells. Hep3B (p53 null) cells, and Chang liver cells. In MTT assay 3', 4'.5. 7-tetrahydoxyflavone showed the most efficient anti-proliferative effects on these three cell lines. However, there was no significant anti-proliferative effect on Chang liver cell line in MTT results. (omitted)

• 건축역사연구
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• 제33권3호
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• pp.7-17
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• 2024

Bunhwangsa Stone Brick Pagoda, constructed in 634, is Korea's oldest stone pagoda. As a prototype of the Silla Stone Pagoda, the pagoda was constructed using flagstones. Since it was constructed with flagstones, it has been known to be a pagoda that replicates the brick pagoda until now. The latest research suggests that it copies the India Stupa or the Stacked Stone Pagoda more than the Brick Pagoda. However, the Bunhwangsa stone brick pagoda has a significant difference in terms of construction technique and shape compared to Brick Pagodas, India Stupas, and Stacked Stone Pagodas. Therefore, it is worth paying attention to the stone building technique used in Silla. Through this study, I would like to clarify that the Bunhwangsa stone brick pagoda is a stone pagoda that creatively reflects the existing Silla stone building techniques such as stone fortresses and stone chamber tombs.

• 복식문화연구
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• 제6권2호
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• pp.22-35
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• 1998

The objective of this study was to investigate and to identify and to classify the fabric names concerning costume in the sumptuary laws of Silla in Sam Guk Sa Ki(三國史記). The important findings of this study can be summarized as follows: Various names of fabrics concerning costume in the sumptuary laws of Silla were found to be classified into ten categories of fabrics. They were as follows: (1) kye( ), (2) Su(繡), (3) Kum(錦), (4) Ra(羅), (5) Reung(綾), (6) Sa(紗), (7) Si( ), (8) Kyun(絹), (9) Myun Ju(綿紬), (10) Po(布). Ra(羅) in ten categories was the most various. The numbering orders shown above were the orders of degree of valuability and preciousness of the fabrics in Silla. Namely, (1) Kye( ) was the most precious fabric, (2) Su(繡) was the second precious one, (3) Kum(錦) was the third precious one, and so on. It was found that the orders of the degree of preciousness of fabrics were a system for differentiating social class and rank, or sex of the people. It revealed the ordering system of the degree of the preciousness of fabrics of Silla was derived from T'ang dynasty. The system of Silla and T'ang system were almost the same each other. Materials used to manufacture fabrics were of mainly three kinds; e.g., wool, silk, and hemp. In these three kinds of materials silk was the most common stuff, and it was seen under the various names of the silks.

• 한국주거학회논문집
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• 제26권6호
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• pp.139-146
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• 2015

In this study, the plane type of main building relics of unified Silla period house site which excavated in Gyeongju city after 1990s was classified and the architectural characteristic of them was investigated. The chronology of building relics in Silla capital city site was mostly known as 8-9th century, and by standard of column arrangement, the plane types of them could be classified as grid type, front veranda-grid type, outer column type. The outstanding characteristic of plane is wide span and open front veranda. In most relics the span were over 4 meters, and inner foundations for small post and strip foundation were found between columns. The front veranda added type buildings were composited of enclosed main room and open front veranda, and column arrangement of them dose not fall into line in most case. Thus it thought that the structures of enclosed main room and open front veranda were independent. The interior space of enclosed main room were divided two rooms by partition wall in some case. In this case, one room is enclosed by wall, and the other room has open front side. This plane is considered for the pleasant life in cold winter and hot summer.

• KSBB Journal
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• 제26권6호
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• pp.552-556
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• 2011

A novel agar-degrading bacterium mbrc-1 was isolated from seashore of Kyungpo at Gangwon province and cultured in marine broth 2216 medium. Isolated bacterium mbrc-1 was named as Flammeovirga sp. mbrc-1 based on the 16S rDNA sequence. Its agarase showed maximum activity of 923 units/L at pH 7.0 and $45^{\circ}C$ and sustained 90% remaining activity after exposed to $45^{\circ}C$ for 2 hours. The enzyme hydrolyzed agarose to yield neoagarohexaose (18.5%), neoagarotetraose (38%) and neoagarobiose (43.5%), indicating that the enzyme is ${\beta}$-agarase. Thus, isolated bacterium and its ${\beta}$-agarase would be useful for the industrial production of neoagarotetraose and neoagarobiose.