• Title/Summary/Keyword: silicon content

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Formulation of Sustained-Release Tablets of Flurbiprofen (서방출성 플루르비프로펜 정제의 제제설계)

  • 이상철;박은석;지상철
    • YAKHAK HOEJI
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    • v.39 no.2
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    • pp.185-192
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    • 1995
  • Flurbiprofen, one of potent nonsteroidal antiinflammatory drugs, has several systemic side effects due to dose dumping effect following oral administration of its conventional solid dosage forms. To reduce these side effects and to sustain therapeutic concentration of the drug, matrix tablets of flurbiprofen were prepared and evaluated for sustained release from the tablets. The matrix tablets of flurbiprofen were prepared with Eudragit, Pluronic, (anhydrous) lactose and colloidal silicon dioxide employing two different preparation methods, wet granulation and direct compression. The dissolution rates of the tablets were evaluated using KP 2 method. Formulation factors that affected dissolution rates of flurbiprofen were the type and content of Eudragit, the type and content of Pluronic, and the tablet preparation method. Several formulations of the matrix tablets showed dissolution patterns close to the simulated profile using pharmacokinetic parameters of flurbiprofen.

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The effects of Si-content on the corrosion rate of Cu-al alloys (동일 알루미늄 합금의 탄식속도에 미치는 규소의 영향)

  • Ham, Dong-Ha;Kang, Tak;Kang, Choon-Sik
    • Journal of the Korean institute of surface engineering
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    • v.14 no.1
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    • pp.5-9
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    • 1981
  • The effects of silicon content on the corrosion rates of Cu-7wt% Al alloys have been investigated by the use of electrochemical methods. The corrosion current densities of the alloys are decreased with the addition of Si up to 2wt%, and the slightly increased at 2.5%Si. This increased corrosion rates are attributed to the precipitation of more anodic gamma-2 phase. The X-ray diffraction tests reveal the dealuminumification of these alloys and mixtures of CuCl and Al2O3 formed on the surface of the specimens, which are considered to passivate the alloys at noble potentials.

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The Effects of Si Content on the Cutting Characteristics in the Turing Process of A1-Si Alloy, Using a Polycrystalline Diamond Tool (다결정 다이아몬드공구를 사용한 Al-Si합금의 선삭과정에서 절삭특성에 미치는 Si함량의 영향)

  • Lee, Kyung-Ho;Yun, Young-Sik;Lee, Sang-Jo
    • Journal of the Korean Society for Precision Engineering
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    • v.12 no.6
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    • pp.20-26
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    • 1995
  • With the recent development of light and high efficient automobiles and aircraft, demand of the A1-Si alloy is rapidly increasing. However, there is an inclination that as the content of silicon increases it becomes more difficult to machine. Accordingly, the present study intends to analyse and study the cutting resistance and surface roughness of A1-Si alloy with Si contents of 8%, 12%, 17%, and 20%. The A1-Si alloy specimens were turned by a poly- crystalline diamond tool under selected cutting conditions, and results are here described and discussed.

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Stress-Free Pyrex-Based Optical Waveguide for Planar Lightwave Circuits on Silicon Substrate (실리콘 기판의 광집적회로를 위한 Pyrex 무응력 도파박막)

  • 문형명;정형곤;이용태;김한수;전영윤;정석종;윤선현;이형종
    • Korean Journal of Optics and Photonics
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    • v.9 no.3
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    • pp.156-161
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    • 1998
  • We developed aerosol flame deposition method and made stress-free Pyrex-based optical waveguide on silicon substrate using this method. Zr is doped to control the refractive index of Pyrex waveguide layers. The refractive index of the film changes from 1.460 to 1.475 as the content of Zr changes from 0 to 3 wt%. Er is doped to see the possibility of applying this Pyrex waveguide as PLC-type (Planar Lightwave Circuit) optical amplifier. The refractive index of the film changes from 1.460 to 1.465 as the content of Zr changes from 0 to 1 wt%. Light launching using a prism coupler to the fabricated waveguide showed good quality for application to PLC. The polarization dependence of refractive-index of the Pyrex film is measured to be less than $2{\times}10^{-4}$.

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Influences of boron and silicon in insert alloys on microstructure and isothermal solidification during TLP bonding of a duplex stainless steel using MBF-35 and MBF-30

  • Yuan, Xinjian;Kim, Myung-Bok;Kang, Chung-Yun
    • Proceedings of the KWS Conference
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    • 2009.11a
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    • pp.59-59
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    • 2009
  • The influences of B and Si in the filler metals on microstructure and isothermal solidification during transient liquid-phase (TLP) bonding of a nitrogen-containing duplex stainless steel with MBF-30 (Ni-4.5wt.%Si-3.2wt.%B) and MBF-35 (Ni-7.3wt.%Si-2.2wt.%B), were studied at the temperature range of $1030-1090^{\circ}C$ with various times from 60 s to 3600 s under a vacuum of approximately $10^{-5}$ Torr. In case of the former, BN, $Ni_3B$ and $Ni_3Si$ precipitates were formed in the bonding region. BN and $Ni_3Si$ secondary phases were present in the joint for the latter case. The formation of $Ni_3B$ within the joint centerline is dependent on B content. The morphology of $Ni_3Si$ is dominated by Si concentration. A difference between the times for complete isothermal solidification obtained by the experiments and the conventional TLP bonding diffusion model was observed when using MBF-35. According to the simulated results, the isothermal solidification completion time for MBF-35 case was smaller than that in MBF-30. However, this experimental value obtained using MBF-35 was notably larger than that obtained using MBF-30. Isothermal solidification of liquid MBF-30 is controlled by the first isothermal solidification regime dependent on B diffusion model, whereas that of liquid MBF-35 experiences two isothermal solidification regimes and is mainly controlled by the second isothermal solidification dependent on Si diffusion model. In addition, only if Si content exceeds a critical value, the slower 2nd solidification regime will commence.

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A Study on Microstructure and Tribological Behavior of Superhard Ti-Al-Si-N Nanocomposite Coatings (초고경도 Ti-Al-Si-N 나노복합체 코팅막의 미세구조 및 트라이볼로지 거동에 관한 연구)

  • Heo, Sung-Bo;Kim, Wang Ryeol
    • Journal of the Korean institute of surface engineering
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    • v.54 no.5
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    • pp.230-237
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    • 2021
  • In this study, the influence of silicon contents on the microstructure, mechanical and tribological properties of Ti-Al-Si-N coatings were systematically investigated for application of cutting tools. The composition of the Ti-Al-Si-N coatings were controlled by different combinations of TiAl2 and Ti4Si composite target powers using an arc ion plating technique in a reactive gas mixture of high purity Ar and N2 during depositions. Ti-Al-Si-N films were nanocomposite consisting of nanosized (Ti,Al,Si)N crystallites embedded in an amorphous Si3N4/SiO2 matrix. The instrumental analyses revealed that the synthesized Ti-Al-Si-N film with Si content of 5.63 at.% was a nanocomposites consisting of nano-sized crystallites (5-7 nm in dia.) and a three dimensional thin layer of amorphous Si3N4 phase. The hardness of the Ti-Al-Si-N coatings also exhibited the maximum hardness value of about 47 GPa at a silicon content of ~5.63 at.% due to the microstructural change to a nanocomposite as well as the solid-solution hardening. The coating has a low friction coefficient of 0.55 at room temperature against an Inconel alloy ball. These excellent mechanical and tribological properties of the Ti-Al-Si-N coatings could help to improve the performance of machining and cutting tool applications.

Preparation and Properties of Silicon Nitride Ceramics by Nitrided Pressureless Sintering (NPS) Process (Nitrided Pressureless Sintering 공정을 이용한 질화규소 세라믹스의 제조 및 특성)

  • Cheon, Sung-Ho;Han, In-Sub;Chung, Yong-Hee;Seo, Doo-Won;Lee, Shi-Woo;Hong, Kee-Soeg;Woo, Sang-Kuk
    • Journal of the Korean Ceramic Society
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    • v.41 no.12 s.271
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    • pp.893-899
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    • 2004
  • The mechanical properties and microstructure and thermal properties of Nitrided Pressureless Sintering(NPS) silicon nitride ceramics, containing three type of $Al_{2}O_3,\;Y_{2}O_3$ sintering additives, were investigated. Also, we have investigated the effect of silicon metal content changing with 0, 5, 10, 15, and $20wt\%$ Si in each composition. In $5wt\%\;Al_{2}O_3,\;5wt\%\;Y_{2}O_3,\;and\;5wt\%$ Si composition, silicon nitride sintered body was successfully densified to a high density. The average 4-point flexural strength and relative density of these specimens were 500 MPa and 98% respectively. Also, Thermal expansion coefficient and thermal conductivity of specimens at room temperature were $2.89{\times}10^{-6}/^{\circ}C\;and\;28W/m^{\circ}C$, respectively. The flexural strength of sintered specimens after thermal shock test of 20,000 cycles was maintained as-received value of 500 MPa.

Studies of Physicochemical Properties of Baby Powder Developed from Rice-flour (쌀 분말을 이용한 유아용 파우더의 이화학적 특성 연구)

  • Han, Sang-Ik;Jang, Ki Chang;Seo, Woo Duck;Oh, Seong-Hwan;Ra, Ji-Eun;Song, Yu-Cheon;Lee, Jong-Hee;Kim, Byung-Joo;Nam, Min-Hee;Lee, Jin-Tae
    • Journal of Life Science
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    • v.23 no.7
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    • pp.879-885
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    • 2013
  • Baby powder is an astringent powder used to prevent diaper rash. It also has other cosmetic uses. In general, it is composed of talc powder (talcum powder). Talc powder is harmful if inhaled because it can cause significant lung damage. With the aim of developing a new rice-based baby powder, three kinds of rice varieties were selected and pulverized. To determine the cost-effectiveness of the different states of rice powder, several milling processes were tried, and the powder characteristics of the resulting rice powder, such as particle size, biological activities, digitalized color value, and moisture content before and after coating treatment with essential oil and silicon oil, were examined. "Goami" showed good flour characteristics with respect to lightness (92.0, $L^*$[D65] value) and particle size ($8.9{\mu}m$). SEM analysis showed that the rice powder particles coated in the essential oil and silicon oil showed a smoother and rounder appearance than those of the talc powder. In addition, the average particle size was decreased by the essential oil and silicon oil coating. The silicon oil coating solved the problem of moisture absorption in rice flour. Rice flour properly coated with essential oil and silicon oil shows great potential as a new material source of powder.

Synthesis of Silicon-Carbon by Polymer Coating and Electrochemical Properties of Si-C|Li Cell (고분자 도포를 이용한 실리콘-탄소의 합성 및 Si-C|Li Cell의 전기화학적 특성)

  • Doh, Chil-Hoon;Jeong, Ki-Young;Jin, Bong-Soo;An, Kay-Hyeok;Min, Byung-Chul;Choi, Im-Goo;Park, Chul-Wan;Lee, Kyeong-Jik;Moon, Seong-In;Yun, Mun-Soo
    • Journal of the Korean Electrochemical Society
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    • v.9 no.3
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    • pp.107-112
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    • 2006
  • Si-C composites were prepared by the carbonization of silicon powder covered by polyaniline(PAn). Physical and electrochemical properties of the Si-C composites were characterized by the particle size analysis, X-ray diffraction technique, scanning electron microscope, and electrochemical test of battery. The average particle size of the Si was increased by the coating of PAn and somewhat reduced by the carbonization to give silicone-carbon composites. XRD analysis' results were confirmed co-existence of crystalline silicon and amorphous-like carbon. SEM photos showed that the silicon particle were well covered with carbonacious materials depend on the PAn content. Si-C|Li cells were fabricated using the Si-C composites and were tested using the galvanostatic charge-discharge test. Si-C|Li cells gave better electrochemical properties than that of Si|Li cell. Si-C|Li cell using the Si-C from HCl undoped PAn Precursor showed better electrochemical properties than that from HCl doped PAn Precursor. Using the electrolyte containing FEC as an additive, the initial discharge capacity was increased. After that the galvanostatic charge-discharge test with the GISOC(gradual increasing of the state of charge) condition was carried out. Si-C(Si:PAn:50:50 wt. ratio)|Li cell showed 414 mAh/g of the reversible specific capacity, 75.7% of IIE(initial intercalation efficiency), 35.4 mAh/g of IICs(surface irreversible specific capacity).

Microstructure and Strength Property of Reaction Sintered SiC Materials (반응소결 SiC 재료의 미세조직 및 강도 특성)

  • LEE SANG-PILL;SHIN YUN-SEOK;LEE JIN-KYUNG
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2004.05a
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    • pp.380-385
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    • 2004
  • The efficiency of complex slurry preparation route for developing the high performance SiC matrix of RS-SiCf/SiC composites has been investigated. The green bodies for RS-SiC materials prior to the infiltration of nw/ten silicon were prepared with various C/SiC complex matrix slurries, which associated with both different sizes of starting SiC particles and blending ratios of starting SiC and carbon particles. The characterization of RS-SiC materials was examined by means of SEM, TEM, EDS and three point bending test. Based on the mechanical property-microstructure correlation, process optimization methodology is also discussed. The flexural strength of RS-SiC materials greatly depended on the content of residual Si. The decrease of starting SiC particle size in the C/SiC complex slurry was effective for improving the flexural strength of RS-SiC materials.

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