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Regional Differences of Entry Rate of Freely Diffusible Substances from Peritoneal Cavity (복강내 확산성 물질의 부위별 흡수속도)

  • Cho, Byeong-Deuck;Shin, Dong-Hoon
    • The Korean Journal of Physiology
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    • v.1 no.2
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    • pp.157-168
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    • 1967
  • The entry of antipyrine and urea from the peritoneal cavity of rabbit into organ tissue and blood plasma was studied. Two hundred mg of antipyrine plus 300 mg of urea in 10 ml Ringer's solution was injected into the peritoneal cavity of anesthetized rabbit. The injection was made from above of a rabbit kept tying right side down and it enabled part of the abdominal organs (liver, intestine, kidney) was immersed in the injected solution and kept high concentration gradient throughout the experimental period. The remaining part of the organs was revered only by a thin film of the test solution. Subsequently, in this part of the organs the concentration gradient of the diffusible substances during entry was presumed to decrease as time elapsed. Four pieces of the liver tissue were taken namely, the right superficial, right deep, left superficial and left deep portions. Two were taken from the small intestine, one from the portion which was immersed in. the fluid and the other from that above the fluid mass. Both kidneys were separately analyzed. As a remote organ the gastrocnemius muscle was taken from the right leg of the animal. The intervals which were the time periods elapsed after injections were 5,7,10,15 or 30 minutes. At each point 5 animals were sacrificed and the concentrations of the test substances in the tissue water were measured. The results obtained were as follows. 1. In the liver the right portion which was immersed in the fluid showed higher concentration if the test substances than the left portion and the superficial region exceeded the deep region. The concentrations diminished as the time elapsed after infusion, particulary in the case of antipyrine, suggesting circulatory removal of the substances. In urea such decreasing tendency of the concentration was not obvious, and suggested slower removal rate of it as compared with that of antipyrine. 2. In the small intestine there was no regional difference in the concentration of the test substances. Because of the intestinal motility different portions of the intestine were seemed to have bathed in the fluid of the same concentration. In general the concentrations in the intestinal wall exceeded those of the liver, suggesting a slower removal rate than in the latter. 3. In the kidney the accumulation of the endogenous urea was predominant, and the accumulating mechanism in the renal tissue went on during the period of the experiment. Therefore it revealed increasing tendencies as the time elapsed. The penetration of the test substances in this organ from the peritoneal cavity seemed to be slower than in other abdominal organs, namely liver or small intestine. Part of the test substances in the kidney were obviously brought by the blood stream. 4. Rapid exponential decay of the concentration of antipyrine and of the osmolality of the peritoneal fluid was attributed to the extensive removal through the whole dimension of the peritoneal surface, and the remote organ such as the gastrocnemius muscle attained a fairly close value to that of the abdominal organs in less than 30 minutes. The factors which related to the absorption rate were discussed. They were the concentration gradient, permeability and the regional perfusion rate.

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Origin and Preservation Status of the 'Gongju Junghakdong Old Missionary House', the Registered Cultural Property No. 233 (등록문화재 제233호 '공주 중학동 구 선교사가옥'의 유래와 보존현황)

  • Suh, Mancheol;Kim, Sung Bae
    • Journal of Conservation Science
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    • v.34 no.1
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    • pp.11-21
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    • 2018
  • The result of the study on the origin and preservation status of the 'Gongju Junghakdong old missionary house', the Registered Cultural Property No. 233, reveals that the building was approved on October 23, 1921, and missionary Alice H. Sharp was living in the building until her retirement from her missionary life of 39 years in Korea in 1939. In order to review internal and external preservation status of the building, condition of wood material, the composition of the window, the damage of the wall, and the leaning of the building were examined. In particular, in the case of window facilities, it is necessary to restore it to the original upper and lower sliding window. As a result of investigation of the preservation status of the external facilities, it is necessary to restore the original shape of the staircase and a deck of the building on south western side and the well. In addition, the results of the non-destructive diagnosis of the ground revealed that the building was built on uneven surface layer of 2-5 m thickness and the boundary between the surface layer and the upper part of the weathered rock is inclined following geomorphology. This phenomenon shows that when the water content of the ground increases in the rainy season, the bearing capacity of the ground is lowered, and there is a possibility of uneven subsidence. Especially, landslides may occur in case of heavy rain. Therefore, it is desirable to install a masonry facility at the southwest boundary of the site, and it is recommended to install a drainage facility to ensure rapid drainage.

Analysis on the Damage and Intensity of the 13 December 1996 Yeongweol Earthquake (1996년 12월 13일 영월지진의 피해 및 진도 분석)

  • 경재복;이기화
    • The Journal of Engineering Geology
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    • v.6 no.3
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    • pp.165-184
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    • 1996
  • The earthquake(M=4.5 by KMA), which occurred in the northeastern part of Yeongweol($37^{\circ}$ 15.75' N, $128^{\circ}$ 42.13' E) on December 13, 1996, shows shallow focal depth(about 8.0km) and relatively large felt area covering most of the southern peninsula. This is the first medium-size earthquake in inland region of the southern peninsula since 1978. It did not trigger foreshock but 13 aftershocks($M{\;}{\geq}{\;}2.5$) for a month. The intensity based on the felt area estimation of about 400 places shows MIMI III-VII in inland region, II on Cheju Island and I on ulreung Island. The isoseismal of MIMI VII shows an elongated circle in the direction of NE-SW and covers some parts of Jungdong-myon, Yeongweol-kun, Sindong-eup and Nam-myun, Jeongseon-kun. There occurred quite strong shaking, numerous cracks on the walls of buildings, falling and movement of slate and tiles on the roofs, falling of tiles from the wall and falling of materials from desks, rock falling from mountain and collapse of gravel layers on the river side. Mainshock and aftershocks occurred condensely between Yemi and Hwaam areas. The felt area due to the Yeongweol earthquake is Quite larger than those of similar size earthquakes in the Korean Peninsula.

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Vaginal Reconstruction with Modified Singapore Flap in MRK Syndrome Patients (MRK증후군 환자에서 변형 Singapore피판술을 이용한 질 재건)

  • Kim, Do-Hoon;Pyon, Jai-Kyong;Mun, Goo-Hyun;Bang, Sa-Ik;Oh, Kap-Sung;Lim, So-Young
    • Archives of Plastic Surgery
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    • v.38 no.5
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    • pp.616-620
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    • 2011
  • Purpose: Mayer-Rokitansky-Kuster syndrome (MRK) is second common cause of primary amenorrhea. It is a syndrome of vaginal aplasia and Mullerian duct anomaly. Vaginal aplasia varies from agenesis of whole vagina to aplasia of upper 2/3. For reconstructing vagina, various methods are introduced. Gracilis myocutaneous flap was the first attempt in that the flap is used in vaginal reconstruction. Various flap-based vaginal reconstruction methods have been introduced. Modified Singapore flap (pedicled neurovascular pudendal thigh fasciocutaneous flap) is one of those methods that used posterior labial artery as pedicle, and pudendal nerve branch as sensory root. As its donor lies on inguinal crease that is easily hidden and there are benefits on sexual intercourse by early sensory recovery, authors think that modified Singapore flap is effective for young MRK syndrome patients. Methods: Eight patients underwent surgery between 2008 and 2010. The flap was designed on both groin area with external pudendal artery branch as a pedicle. All flaps were fixated in pelvic cavity with absorbable suture, and additional compression on neovaginal wall was supplied by polyvinyl alcohol sponge ($Merocel^{(R)}$). Results: All patients were successfully reconstructed without flap related complications such as congestion or partial flap loss. The average size of the flap (each side) was 69.34 $cm^2$. Polyvinyl alcohol sponge ($Merocel^{(R)}$) was inserted into neovagina for 5 days on every patient. One case of rectal laceration was occurred while making pelvic pocket by OBGY team. Other complications such as lumen narrowing, wound contracture or vaginal prolapsed were not reported during 8 months of follow up. Conclusion: Modified Singapore flap is a sensate fasciocutaneous flap that is thinner than other myocutaneous flap such as VRAM, and more durable over skin graft. Therefore this is a good choice for vaginal reconstruction in MRK syndrome. And known complications of Modified Singapore flap could be reduced with careful procedure and mild compression techniques.

A study on the structural behaviour of shotcrete and concrete lining by experimental and numerical analyses (숏크리트 및 콘크리트 라이닝의 역학적 거동에 관한 실험 및 수치해석적 연구)

  • 김재순;김영근
    • Tunnel and Underground Space
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    • v.8 no.4
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    • pp.307-320
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    • 1998
  • Tunnel lining is the final support of a tunnel and reflects the results of the interaction between ground and support system. Recently it is very difficult to support and manage the tunnel because the cracks on tunnel lining cause many problems in supporting and managing tunnels. Therefore the analysis of the cracks is quite strongly required. In this study, mechanical behaviour of a tunnel lining was examined by model tests and by numerical analyses. Especially the model test was examined for double linings including shotcrete and concrete lining. The model tests were carried out under various conditions taking different loading shapes, horizontal stresses, thicknesses of linings and double lining, vault opening behind the concrete lining and rock-like medium surrounding the lining. Due to horizontal stress, compressive stress prevailed on the lining. Thus the bearing capacity of the lining increased. The existence of a vault opening behind the concrete lining reduced the bearing capacity by the similar amount of reduction of concrete lining thickness. Rock-like medium cast around the side wall of the lining restrained the deflection of the lining, and the bearing capacity for cracking and failure increased vary much. In numerical analyses a algorithm which can analysis the double lining by introduction of interface element was developed. And the results of the numerical analyses were compared with the results of the model tests.

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Geomechanical Stability of Underground Lined Rock Caverns (LRC) for Compressed Air Energy Storage (CAES) using Coupled Thermal-Hydraulic-Mechanical Analysis (열-수리-역학적 연계해석을 이용한 복공식 지하 압축공기에너지 저장공동의 역학적 안정성 평가)

  • Kim, Hyung-Mok;Rutqvist, Jonny;Ryu, Dong-Woo;Synn, Joong-Ho;Song, Won-Kyong
    • Tunnel and Underground Space
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    • v.21 no.5
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    • pp.394-405
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    • 2011
  • In this paper, we applied coupled non-isothermal, multiphase fluid flow and geomechanical numerical modeling using TOUGH-FLAC coupled analysis to study the complex thermodynamic and geomechanical performance of underground lined rock caverns (LRC) for compressed air energy storage (CAES). Mechanical stress in concrete linings as well as pressure and temperature within a storage cavern were examined during initial and long-term operation of the storage cavern for CAES. Our geomechanical analysis showed that effective stresses could decrease due to air penetration pressure, and tangential tensile stress could develop in the linings as a result of the air pressure exerted on the inner surface of the lining, which would result in tensile fracturing. According to the simulation in which the tensile tangential stresses resulted in radial cracks, increment of linings' permeability and air leakage though the linings, tensile fracturing occurred at the top and at the side wall of the cavern, and the permeability could increase to $5.0{\times}10^{-13}m^2$ from initially prescribed $10{\times}10^{-20}m^2$. However, this air leakage was minor (about 0.02% of the daily air injection rate) and did not significantly impact the overall storage pressure that was kept constant thanks to sufficiently air tight surrounding rocks, which supports the validity of the concrete-lined underground caverns for CAES.

Echinostoma macrorchis Metacercariae in Cipangopaludina chinensis malleata from Xiengkhuang Province, Lao PDR and Morphologies of Adults from Experimental Animals

  • Sohn, Woon-Mok;Na, Byoung-Kuk;Lee, Dongmin;Eom, Keeseon S.;Yong, Tai-Soon;Chai, Jong-Yil;Min, Duk-Young
    • Parasites, Hosts and Diseases
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    • v.57 no.6
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    • pp.657-664
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    • 2019
  • We identified the echinostome metacercariae in Chinese mystery snails, Cipangopaludina chinensis malleata, from Xiengkhuang Province, Lao PDR with morphologies of adult worms recovered. Total 20 snails were examined with artificial digestion method and then the collected metacercariae were orally infected to a mouse and a rat. Adult worms recovered from experimental animals were observed with a light microscope and a SEM. The metacercariae were round, 125×123 ㎛ in average size, with a moderately thick cyst wall, collar spines distributed in the head collar and excretory granules in 2 canals of excretory tube. Adult flukes (3-week-old in a rat) were elongated, ventrally curved and 5.310×1.023 mm in average size. Head collar distinct, bearing 43 collar spines with 5 end group ones on each side. Oral sucker subterminal, prepharynx very short, pharynx well developed, and esophagus relatively short. Cirrus sac well developed, with a saccular seminal vesicle, and ventral sucker very large. Ovary round and on the median line of the body. Testes tandom and elongated. Eggs operculated, elliptical and 90×57 ㎛ in average size. In the SEM observation, the head crown prominent, with 43 collar spines resembled with horns of younger stag. Scale-like tegumental spines were densely distributed on the surface between the head collar and ventral sucker, and their densities were decreased posteriorly. Conclusively, the metacercariae detected in C. chinensis malleata from Lao PDR were identified as those of Echinostoma macrorchis based on the morphological characteristics of adult worms.

Odor Removal Efficiency of Biofilter Ducting Systems in Indoor Pig House (바이오 필터를 이용한 비육돈사 배기덕트 시설의 악취저감 효과)

  • Song, J.I.;Choi, H.L.;Choi, H.C.;Kwon, D.J.;Yoo, Y.H.;Jeon, J.H.
    • Journal of Animal Environmental Science
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    • v.13 no.3
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    • pp.195-200
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    • 2007
  • Management of odors is essential to swine industry in the Republic of Korea. This study was conducted to evaluate the odor removal efficiency of biofilter ducting systems. Rice straw and auto clave concrete(ALC) were used as filter medium. The ventilation fans(5 units, diameter: 500 mm) at the side wall of a growing pig housing were connected to a biofilter using a duct. The size of a biofilter is $2.5{\times}2{\times}1.2(W{\times}L{\times}H)$. The air velocities at the 300 mm above rice straw and ALC were 0.77 and 0.56 m/s, respectively. Ammonia concentration at the outlet of rice straw and ALC media were 2 and 3 ppm, respectively. Dust concentrations were also measured. The dust concentrations of rice straw and ALC were 93, $32\;mg/m^3$, respectively. There was no significant difference between filter mediums in terms of carbon dioxide concentrations(rice straw: 320, ALC: 270 mg/l). The concentration of hydrogen sulfide was stable over the experimentation. The actual concentrations of hydrogen sulfide were 4, 3 and 3 ppm at the days of 7, 21 and 36, respectively. These results suggest that biofilter ducting systems may remove odors from pig house effectively.

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Experimental analysis of geomorphic changes in weir downstream by behavior of alternate bar upstream (보 상류 교호사주의 거동에 따른 하류 지형변화에 대한 실험적 분석)

  • Lee, KyungSu;Jang, Chang-Lae;Kim, GiJung
    • Journal of Korea Water Resources Association
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    • v.52 no.spc2
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    • pp.801-810
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    • 2019
  • This study analyzes the impact on geomorphic changes downstream due to alternate bars developed weir upstream through laboratory experiments. The disturbance, such as a spur in the side wall, of the flow at the inlet of the channel triggers the development of alternate bar upstream at the beginning of the experiment, and gradually moved downstream with keeping their shapes over time. The bed in the downstream of weir in the mid of channel scoured due to the scarcity of sediment inflow because weir upstream traps it. Moreover, bar migration speed decreases as the bars approaches to the weir with time. However, as time increases, the alternate bars upstream migrate over the weir, and sediment in the eroded bed of the weir downstream are deposited. The phase of the bar upstream changes oppositely after passing through the weir. The phase of the bar downstream changes rapidly as the shape of alternate bar is clear upstream, which is affected by the strong disturbance. The phase of bar changes, and the bar migration speed decreases gradually with time, and finally stopped due to forcing effects on the bar by the disturbance. The faster the reaction of alternate bar with a long spur, the larger the bar height formed downstream and the shorter the bar length. This means that the larger the forcing effect of bar, the more it affects the bar migration. In addition, although the size of the alternate bar increases over time, the bar doesn't migrate downstream and a forced bar is generated.

A Study on the Uniform Mixing of Ammonia-Air with the Change of Ammonia Supply Device Shape in a De-NOx System (탈질설비에서 암모니아 혼합기의 형상에 따른 암모니아-공기 균일 혼합에 관한 연구)

  • Ha, Ji Soo
    • Journal of the Korean Institute of Gas
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    • v.23 no.3
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    • pp.20-26
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    • 2019
  • Selective catalytic reduction(SCR) method is widely used among various methods for reducing nitrogen oxides in combustion devices of coal power plant. In the present study, the computational fluid dynamic analysis was accomplished to derive the optimal shape of ammonia-dilution air mixing device in a ammonia injection grid. The distribution characteristics of flow and $NH_3$ concentration had been elucidated for the reference shape of ammonia mixing device(Case 1). In the mixing device of Case 1, it could be seen that $NH_3$ distribution was shifted to the wall opposite to the inlet of the ammonia injection pipe. For the improvement of $NH_3$ distribution, the case(Case 2) with closing one upper injection hole and 4 side injection holes, the case(Case 3) with installing horizontal plate at the upper of ammonia injection pipe, the case(Case 4) with installing horizontal plate and horizontal arc plate at he upper of ammonia injection pipe were investigated by analyzing flow and $NH_3$ concentration distributions. From the present study, it was found that the % RMS of $NH_3$ for Case 4 was 4.92%, which was the smallest value among four cases, and the range of $R_{NH3}$ also has the optimally uniform distribution, -10.82~8.34%.