• Title/Summary/Keyword: side-effects

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Flow Characteristics of Gamcheon Harbour (감천항의 해수유동 특성)

  • 김기철;김재중;장필훈
    • Journal of Korean Port Research
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    • v.13 no.2
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    • pp.409-418
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    • 1999
  • Gamcheon Bay has complicated and unique flow pattern which is affected by topography characteristics of a semi-closed bay and warm water discharge from the power plant located at the bay. It is very important to consider warm water discharge with tidal period and wind effects, which are mainly acting on the surface flow patterns in Gamcheon Bay. The results of observation show as follows; i) Because Gamcheon bay has much elongated shape to the north-south direction and narrow entrance with two separated breakwaters, the flow is very weak inside the bay. ii) The main flow path is at the west side of the bay. The direction of flood current is northward along the west side of the bay and the direction of ebb current is southward along the west side of the bay. The southward direction of warm water discharge has curved to the west side of the bay. iii)At the period of flood current for neap tide, the flow direction is southward in the bay, which is thought by the effects of warm water discharge. But at the bottom layer, the effects of tidal current reached to the middle of the bay, and showed features like eddy. iv) The wind effect is very strong, especially, prominent in the west and east side of the bay.

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Adverse Event Report in Cattle Following Foot-and-Mouth Disease Vaccination in Daejeon Province (대전지역 소에서 구제역 백신 접종후의 부작용에 대한 조사)

  • Jeong, Sangil;cho, Daehee;Cho, Nayoung;Park, Seongjun
    • Journal of Veterinary Clinics
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    • v.37 no.6
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    • pp.324-330
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    • 2020
  • Few studies of the side effects of the FMD vaccine have been performed domestically and studies in accordance to region have been limited. This study was performed by inoculating cows raised in the Daejeon province with the FMD vaccine and observing the side effects following inoculation. From January to February of 2011, 3,378 cows vaccinated with the FMD vaccine, in 143 different farms in the Daejeon province were analysed for adverse effects after inoculation. A total of 66 cows showed adverse effects after the first FMD vaccination and adverse effects observed were abortion/stillbirth (24, 36.4%), death (19, 28.8%), premature birth (14, 21.2%), skin lesions (8, 12.1%), vaginal swelling (1, 1.5%). A total of 29 cows showed adverse effects after the second FMD vaccination and adverse effects observed were abortion/stillbirth (17, 58.6%), premature birth (5, 17.2%), facial swelling (4, 13.8%), death (3, 10.3%). Through these results, continuous national research of the side effects of the FMD vaccine should be carried out continuously henceforth.

The protective effects of trace elements against side effects induced by ionizing radiation

  • Hosseinimehr, Seyed Jalal
    • Radiation Oncology Journal
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    • v.33 no.2
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    • pp.66-74
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    • 2015
  • Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

A Case of Central Nervous System Toxicity Associated with Cyclosporine (Cyclosporine에 의한 중추신경계 독성 1례)

  • Lee Do-Yoon;NamGoong Mee-Kyung;Kim Hwang-Min;Lim Baek-Keun
    • Childhood Kidney Diseases
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    • v.1 no.2
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    • pp.179-182
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    • 1997
  • Cyclosporine is an immunosuppressant usually used to prevent renal transplantation rejection. Nephrotoxicity and hypertension are considered as the most frequent side effects of cyclosporine treatment. The neurotoxic effects of cyclosporine such as agitation, anxiety, delirium, depression and psychosis have recently been found. Methylprednisolone may increase as well plasma concentration of cyclosporine, which leads to side effects. Here we report a $Henoch-Sch\"{o}nlein$ nephritis patient treated with cyclosporine and methylprednisolone who has experienced psychosis including visual and auditory hallucination and convulsion.

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Change in Curl of Newsprint by Physical Treatments - Effects of roll diameter, storage time, winding methods, calendering and humidity on curl - (물리적 처리에 의한 신문용지의 컬 변화 -권취롤의 직경, 저장 기간, 권취 방법, 캘린더링 및 습도의 영향-)

  • Lim, Yeon-Ju;Paik, Ki-Hyon
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.36 no.3
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    • pp.60-66
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    • 2004
  • The effects of roll diameter, winding time, winding methods and relative humidity on curl In newsprints(46$g/m^2$, 54 $g/m^2$, and 54 $g/m^2$ SNC) are examined. The larger MD curl appears at smaller roll diameter, with the extension of winding time, and at the treat ment of soft nip calendering. The MD curl shows the back side curl at winding methods with top side as outer side(TSO), and the top side curl with top side as inner side(TSI). While the CD curl in newsprints( 46 $g/m^2$, and 54 $g/m^2$ SNC) treated with calender is hardly influenced by the storage times, roll diameter, and winding methods. However the CD curl in newsprint(54 $g/m^2$) gradually increases to a two weeks, and then hold constant regardless of roll diameter and winding methods.. The CD curl shows always the top side curl regardless of winding methods. At high relative humidity, the CD curl largely reduces, but the MD curl is not nearly changed. Especially, the CD curl in news-prints(54 $g/m^2$ SNC) is little affected by the changes of relative humidity.

Contrast Media Side Effects Prediction Study using Artificial Intelligence Technique (인공지능 기법을 이용한 조영제 부작용 예측 연구)

  • Sang-Hyun Kim
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.423-431
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    • 2023
  • The purpose of this study is to analyze the factors affecting the classification of the severity of contrast media side effects based on the patient's body information using artificial intelligence techniques to be used as basic data to reduce the degree of contrast medium side effects. The data used in this study were 606 examiners who had no contrast medium side effects in the past history survey among 1,235 cases of contrast medium side effects among 58,000 CT scans performed at a general hospital in Seoul. The total data is 606, of which 70% was used as a training set and the remaining 30% was used as a test set for validation. Age, BMI(Body Mass Index), GFR(Glomerular Filtration Rate), BUN(Blood Urea Nitrogen), GGT(Gamma Glutamyl Transgerase), AST(Aspartate Amino Transferase,), and ALT(Alanine Amiono Transferase) features were used as independent variables, and contrast media severity was used as a target variable. AUC(Area under curve), CA(Classification Accuracy), F1, Precision, and Recall were identified through AdaBoost, Tree, Neural network, SVM, and Random foest algorithm. AdaBoost and Random Forest show the highest evaluation index in the classification prediction algorithm. The largest factors in the predictions of all models were GFR, BMI, and GGT. It was found that the difference in the amount of contrast media injected according to renal filtration function and obesity, and the presence or absence of metabolic syndrome affected the severity of contrast medium side effects.

Effects of Acupuncture at Palsa(BaXie) Evaluated by the Second Derivative of Photoplethysmogram Waveform in Hemiparetic Patients after Stroke (편마비 환자에서 팔사혈(八邪穴) 자침(刺鍼)이 가속도맥파에 미치는 영향)

  • Yeo, Kyeong-Chan;Yoon, In-Ae;Kim, Ji-Na;Bang, Sung-Pil;Moon, Sung-Il
    • Journal of Acupuncture Research
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    • v.27 no.2
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    • pp.23-30
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    • 2010
  • Objectives : The second derivative of photoplethysmogram waveform(SDPTG) is a simple, convenient and non-invasive technique for pulse wave analysis. This study was designed to investigate the differences in the SDPTG between the affected side and the unaffected side in hemiparetic patients after stroke, and the effects of acupuncture at Palsa(BaXie) in hemiparetic patients after stroke. Methods : To evaluate the differences between the affected side and the unaffected side in hemiparetic patients after stroke, their SDPTG were recorded by using a Cardio Peri SA6000. To evaluate the effects of acupuncture at Palsa(BaXie) in 20 hemiparetic patients after stroke and 20 healthy subjects, their SDPTG were recorded 2 times(pre-acupuncture and post-acupuncture). The SDPTG consists of an a, b, c and d wave in systole and an e wave in diastole. Sano aging index was defined as (b-c-d)/a. Results : 1. The affected side in hemiparetic patients after stroke had higher average b/a ratio(p<0.05)and Sano aging index(p<0.05) than the unaffected side 2. In a comparison of pre-acupuncture and post-acupuncture at the Palsa(BaXie), b/a ratio(p<0.05) and Sano aging index(p<0.05) was decreased significantly in both hemiparetic patients and healthy subjects. Conclusions : These findings suggest that acupuncture at Palsa(BaXie) may be effective method of reverting some of the deleterious effects on vascular function produced by stroke.

The Comparative Study of Butorphanol Versus Ketoprofen: Effect and Safety in Postoperative Pain Control after Hysterectomy (자궁적출술 후 통증관리를 위하여 투여된 Butorphanol과 Ketoprofen의 효과 및 안전성에 관한 비교연구)

  • Lim, Young-Jin;Lee, Sang-Chul
    • The Korean Journal of Pain
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    • v.11 no.2
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    • pp.258-262
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    • 1998
  • Background: In view of the safety and effectiveness of butorphanol as a postoperative analgesic, we designed to compare its activity and side effects with those of ketoprofen, when administered intramuscularly. Methods: Ninety four patients, scheduled for elective total abdominal hysterectomy, received either ketoprofen 100 mg (ketoprofen group) or butorphanol 2 mg (butorphanol group) intramuscularly after surgery. For the first six hours after injection of butorphanol or ketoprofen, the patients were asked to reevaluate the intensity of pain, using numeric rating scale (NRS) and pain score. If the pain score was above 2, supplemental ketoprofen was administered IM. Incidence of side effects were also checked. Results: Butorphanol group showed lower NRS and pain score for the first four hours compared to ketoprofen group, but the incidence of drowsiness was higher in butorphanol group. There were no significant difference in the incidence of other side effects such as nausea and dizziness. In both group, there were neither respiratory depression nor pruritus. Conclusions: Butorphanol gave better relief of postoperative pain compared to ketoprofen. Butorphanol might be a useful drug for postoperative analgesia after hysterectomy with minor side effects.

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Clinical Report on One Case of Pulmonary Tuberculosis Using Oriental Medicine with Western Medicine (한(韓).양방(洋方) 겸치(兼治)로 치유된 폐결핵 환자 1례)

  • Jang, Soo-Young;Yoo, Hyo-Jeong;Yoon, Keong-Min;Im, Eun-Young;Shin, Hyeon-Cheol
    • The Journal of Internal Korean Medicine
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    • v.31 no.1
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    • pp.177-188
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    • 2010
  • Objective : This study was designed to evaluate the treatment effects and the prevention of side effects from antituberculosis drugs by using oriental medicine on a pulmonary tuberculosis patient. Methods : The clinical data was analyzed on a patient with pulmonary tuberculosis whose main symptoms were general weakness, anorexia, weight loss, tachycardia, night sweats, fever, coughing and chest pain. The patient was treated from June 17, 2008 to April 1, 2009, using herbal medicine (Cheongpyebyeolgab-tang) with antituberculosis drugs. Results : After treatment, the symptoms disappeared faster than with western medicine treatment only. Laboratory examinations and radiograph impressions also improved. No side effects of the antituberculosis drugs were noted. Conclusions : This suggests that oriental medicine therapy is effective for pulmonary tuberculosis and prevents the side effects of the antituberculosis drugs.

Comparison of the Level and Side Effects of Spinal Anesthesia with Hyperbaric Bupivacaine in the Supine, Lateral, and Prone Positions (고비중 Bupivacaine 척추마취 후 체위에 따른 마취수준과 부작용의 비교)

  • Moon, Ji Young;Kim, Bo Hwan
    • Journal of Korean Biological Nursing Science
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    • v.17 no.2
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    • pp.114-122
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    • 2015
  • Purpose: This study attempted to test whether there are differences in the level and hemodynamic side effects (blood pressure, heart rate, $O_2$ saturation), and nausea & vomiting of spinal anesthesia using hyperbaric bupivacaine according to position (supine, lateral, and prone positions) in orthopedic surgery patients who received podiatric surgery under spinal anesthesia. Methods: This study was conducted with 53 patients who had received orthopedic surgery under spinal anesthesia at I General Hospital. Data were analyzed using SPSS 20.0 through repeated-measures ANOVA, post-hoc test, Chi-test, and Fisher's exact test. Results: The change of position after spinal anesthesia with hyperbaric bupivacaine caused a change in the level of spinal anesthesia (F=12.768, p<.001). However, no difference of blood pressure, heart rate, $O_2$ saturation and nausea and vomiting caused by the change in anesthesia level was observed, and in prone position, drug was administered for the correction of side effects. Conclusion: As expected, recognizing that there can be a change in the level of spinal anesthesia after the change of position in surgical patients, nurse anesthetists should monitor their conditions carefully and continuously.