• 제목/요약/키워드: side-effects

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Factors Influencing COVID-19 AstraZeneca (ChAdOx1) Vaccination and Side Effects among Health Care Workers in an Acute General Hospital (중소병원 의료기관 종사자의 COVID-19 AstraZeneca (ChAdOx1) 백신 접종 영향요인과 접종 후 이상 반응 실태조사)

  • Lee, Sunhwa;Choi, Jeong Sil
    • Journal of Korean Biological Nursing Science
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    • 제23권4호
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    • pp.318-329
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    • 2021
  • Purpose: This study was conducted to identify factors affecting COVID-19 vaccination and associated side effects among health care workers in a small and medium-sized hospital. Methods: In May 2021, 301 workers out of a total of 670 working in a small and medium-sized hospital in Gyeonggi-do, were surveyed. The small and medium-sized hospital treats patients with COVID-19. Health care workers across different medical institutions responded with self-reported internet questionnaires. Factors influencing COVID-19 vaccination were analyzed via logistic regression. Results: Out of 301 subjects, 89.0% showed an intention to inoculate, and 85.7% were vaccinated against COVID-19. The most frequent reason for vaccination was responsibility as a medical worker. The fear of adverse reactions was the most frequent reason for non-vaccination. Adverse reactions after inoculation occurred in 70.9% of cases, and 30.6% were referred for treatment of adverse reactions. The factors ultimately influencing COVID-19 vaccination were vaccination intention, previous side effects from other vaccinations, occupation, and age. Conclusion: In order to improve the effectiveness of COVID-19 vaccination, a systematic approach is required to determine the risk factors associated with the young age of the administrative staff/personnel, subjects with a history of side effects associated with other vaccines, and health care workers who do not intend to be vaccinated. It is important to develop strategies to improve immunization. In addition, accurate and essential information regarding the side effects of vaccination is needed, along with appropriate education and publicity.

Current Guidelines for Non-Steroidal Anti-Inflammatory Drugs (비스테로이드 소염제의 최신 사용 지침)

  • Park, Min-Gyue;Yoo, Jae-Doo;Lee, Kyu-Ho
    • Journal of the Korean Orthopaedic Association
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    • 제55권1호
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    • pp.9-28
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    • 2020
  • Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs worldwide for chronic pain, such as arthritis, and there are many different types depending on their composition and mechanism. After long-term use, various side effects can occur, such as gastrointestinal and cardiovascular complications. With a similar analgesic effect to that of traditional non-selective NSAIDs, cyclooxygenase-2-selective NSAIDs have been highly anticipated, because they could complement gastrointestinal tolerance. On the other hand, because of concerns about cardiovascular safety in 2004 and 2005, and the license withdrawals of rofecoxib and valdecoxib, the interest in the side effects of NSAIDs is increasing. Therefore, it is important to use the necessary drugs at a minimum, considering the side effects and interactions of each drug. This study examined the side effects and characteristics of each NSAID that may occur and reviewed the recent research and guidelines related to the use of non-selective NSAIDs and cyclooxygenase-2-selective NSAIDs.

Thermographic Study on the Effects of Deep Acupuncture at Hapkok(LI4) in Cerebrovascular Hemiplegia (적외선 체열 촬영을 이용한 중풍(中風) 편마비(片痲痺) 환자(患者)의 합곡혈(合谷穴) 일반 자침시(刺針時)와 심자시(深刺時) 피부온도변화(皮膚溫度變化) 관찰(觀察))

  • Park, Young-chul;Chae, Jin-seok;Eom, Jae-yong;Son, Sung-se;Choe, Ick-seon
    • Journal of Acupuncture Research
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    • 제20권4호
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    • pp.134-144
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    • 2003
  • Objective : This study designed to find out the effects of deep acupuncture in cerebrovascular hemiplegia. Methods : This study was performed on 30 patients with cerebrovascular hemiplegia to observe difference in temperature of skin surface between general acupuncture and deep acupuncture at Hapkok using digital infrared thermographic imaging(D.I.T.I.) Results : 1. Temperature of paralytic side is sigficantly higer $0.39{\pm}0.78^{\circ}C$ than that of contralateral side. 2. Thermal difference(${\Delta}T$) of paralytic side-contralateral side decreased $0.08{\pm}0.53^{\circ}C$ after general acupuncture, but there is no significant. $0.20{\pm}0.50^{\circ}C$ after deep acupuncture decreased significantly. So deep acupuncture is more effective than general acupuncture. 3. Thermal difference of paralytic side-paralytic side and contralateral side-contralateral side decreased significantly after acupuncture, and thermal difference of deep acupuncture on paralytic side-paralytic side decreased $0.42{\pm}1.07^{\circ}C$ more than that of general acupuncture. So deep acupuncture is more effective than general acupuncture. Conclusions: This study showed that deep acupuncture is more effective than general acupuncture In cerebrovascular hemiplegia, and further study is needed on clinical trials.

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Effects of Pressure-Side Winglet at an Elevation of Tip Surface on the Tip-Leakage Flow and Aerodynamic Loss Downstream of a Turbine Blade Equipped with Pressure-Side Squealer Tip (압력면익단소익이 터빈 동익 압력면스퀼러팁 하류의 팁누설유동 및 압력손실에 미치는 영향)

  • Cheon, Joo Hong;Lee, Sang Woo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • 제40권10호
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    • pp.645-651
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    • 2016
  • Effects of pressure-side winglet width on the tip leakage flow and aerodynamic loss downstream of a turbine blade with a pressure-side squealer rim have been investigated for the tip gap-to-span ratio of h/s = 1.36%. The pressure-side squealer has a fixed height-to-span ratio of $h_p/s=3.75%$ and the pressure-side winglet, which is installed at an elevation of tip surface, has width-to-pitch ratios of w/p = 2.64%, 5.28%, 7.92% and 10.55%. The results show that with increasing w/p, aerodynamic loss in the passage vortex region decreases, whereas that in the leakage flow region increases. As a result, the mass-averaged loss coefficient all over the measurement plane tends to decrease minutely with the increment of w/p. It is concluded that the pressure-side winglet for the pressure-side squealer tip can hardly contribute to the tip-leakge loss reduction.

The Effects of Vibration and Side-lying Hip Abduction on Pain, Disability, Strength and Balance in Individuals with Low Back Pain (진동을 동반한 옆교각 운동이 요통 성인의 통증, 기능장애, 근력, 균형에 미치는 영향)

  • Gwon, Ae-Jeong;Kim, Suhn-Yeop
    • Journal of the Korean Society of Physical Medicine
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    • 제11권4호
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    • pp.127-137
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    • 2016
  • PURPOSE: This study aimed to compare the effects of side-lying hip abduction exercise with and without vibration on pain, disability, strength and balance in individuals with low back pain. METHODS: 30 participants enrolled in this study were randomly assigned to an experimental group (EG, n=15) for side-lying hip abduction with vibration and a control group (CG, n=15) for side-lying hip abduction without vibration. Both groups were treated 3 times per week for 4 weeks. Pain (Numeric Rating Scale), disability (Korean Oswestry Disability Index), hip abductor muscle strength, and static balance were measured in both groups before and after the program. Results were analyzed using paired t-test for comparing the difference within the group and independent t-test for comparing the difference between two groups. RESULTS: Compared to the CG, the EG showed significantly greater reductions in pain and disability (p<.05). There was a significant difference in all balance categories of both the painful and non-painful sides within the EG (p<.05). Balance showed a significant decrease except the envelope area (ENV) on the non-painful side within the CG (p<.05). There was a significant increase in all balance categories except ENV of non-painful side between the two groups (p<.05). Balance increased on both the painful and non-painful sides in the EG. Balance improved on the painful side in the CG, but significantly decreased on the non-painful side (p<.05). CONCLUSION: Side-lying hip abduction exercise with vibration is considered an effective treatment for pain, disability and balance in individuals with low back pain.

Inhibitory Effects of Banhasasim-tang Extracts on Cisplatin-induced Body Weight Decrease in Mouse Model (시스플라틴 유도 체중감소에 대한 반하사심탕 추출물의 방어효과)

  • Kim, Ha Rim;Kim, Mi Seong;Lee, Young Rae;Ryu, Do Gon;Lim, Chan Han;Kim, Byung Sook;Lee, Geum-San;Kwon, Kang Beom
    • Journal of Physiology & Pathology in Korean Medicine
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    • 제31권6호
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    • pp.362-366
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    • 2017
  • In this study, Banhasasim-tang extracts (BSTE) have an inhibitory effects on cisplatin-induced decrease of body weights in two mouse model. Cisplatin is the most widely used anticancer drug for treatment of various cancer. However, cisplatin treatment to cancer patients leads to many side effects such as nausea, vomiting and body weight decrease. BSTE has been used to decrease digestive disorders in South Korea. We hypothesize that BSTE improve the cisplatin-induced side effects in mouse models. We found that pre- and co-administration of BSTE inhibited decreases of body weights and food intake by cisplatin in mouse models. But BSTE had no synergistic effects for tumor shrinkage by cisplatin in xenograft model. Collectively, our data suggest that BSTE have great potential as a agent for having decrease effects on side effects by cisplatin in cancer patients.

Dilution and Thermal Effects of N2 Addition on Soot Formation in Co-flow Diffusion Flame (동축류 확산화염에서 질소첨가가 Soot발생에 미치는 영향)

  • Eom, Jae-Ho;Lee, Jong-Ho;Jeon, Chung-Hwan;Chang, Young-June
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2002년도 제24회 KOSCO SYMPOSIUM 논문집
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    • pp.185-191
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    • 2002
  • The influence of N2 addition on soot formation, flame temperature and NOx emissions is investigated experimentally with methane fuel co-flow diffusion flames. The motivation of the present investigation is the differences in NOx reduction reported between fuel-side and oxidizer-side introduction of N2. To determine the influence of dilution alone, fuel was diluted with nitrogen while keeping the adiabatic flame temperature fixed by changing the temperature of the reactants. And to see the thermal effect only, air was supplied at different temperature without N2 addition. N2 addition into fuel side suppressed the soot formation than the case of oxidizer-side, while flame temperature enhanced the soot formation almost linearly. These results reveals the relative influences of the thermal, concentration effects of N2 additives on soot formation In accordance with experimental study, numerical simulation using CHEMKIN code was carried out to compare the temperature results with those acquired by CARS measurement, and we could find that there is good agreement between those results. Emission test revealed that NOx emissions were affected by not only flame temperature but also N2 addition.

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Change in Pelvic Motion Caused by Visual Biofeedback Influences Trunk and Hip Muscle Activities During Side-Lying Hip Abduction in Asymptomatic Individuals

  • Yu, Ilyoung;Kang, Minhyeok
    • Journal of International Academy of Physical Therapy Research
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    • 제10권3호
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    • pp.1818-1822
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    • 2019
  • Background: Ipsilateral pelvic elevation has been reported as a common compensatory movement during side-lying hip abduction. It has been reported that pelvic elevation inhibits sufficient contraction of gluteus medius. However, few studies have identified the effects of controlled pelvic elevation on the trunk and hip muscles. Objective: To examine the effects of controlled pelvic elevation using visual biofeedback on the muscle activity of the trunk and hip muscles. Design: Crossover study. Methods: Twelve healthy males performed side-lying hip abduction exercises with and without visual biofeedback for pelvic elevation. Electromyography (EMG) activities of the gluteus medius, quadratus lumborum, and multifidus were analyzed using a wireless EMG system while the ipsilateral pelvic elevation angle was measured using a motion sensor during side-lying hip abduction exercises. Results: EMG activities of the gluteus medius (p = .002), quadratus lumborum (p = .022), and multifidus (p = .020) were significantly increased and ipsilateral pelvic elevation was significantly decreased (p = .001) during side-lying hip abduction with visual biofeedback compared to without visual biofeedback. Conclusions: The results of this study suggest that the application of biofeedback for pelvic motion could improve the trunk and hip muscle activation pattern and decrease compensatory pelvic motion during side-lying hip abduction exercise.

Effects of Functional Electrical Stimulation (FES) on the Temporal-spatial Gait Parameters and Activities of Daily Living in Hemiplegic Stroke Patients

  • Oh, Dong-Gun;Yoo, Kyung-Tae
    • Journal of the Korean Society of Physical Medicine
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    • 제16권3호
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    • pp.37-44
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    • 2021
  • PURPOSE: This study examined the effects of functional electrical stimulation (FES) on temporal-spatial gait and the activities of daily living in hemiplegic stroke patients. METHODS: The subjects were 29 hemiplegic stroke patients (57.7 ± 10.3). The patients walked at a self-controlled speed in four states: (1) walking without FES (non-FES), (2) walking with FES on the gluteus medius in the stance phase (GM), (3) walking with FES on the common peroneal nerve and tibialis anterior in the swing phase (PT), (4) walking with both GM and PT. A GAITRite system, Timed-Functional Movements battery, and Timed UP and Go test were used to measure the variables. RESULTS: Significant improvements were observed in all variables of the GM+PT, GM, and PT states compared to the non-FES state (p < .05). There were significant improvements in the GM+PT state compared to GM and PT states (p < .05). Moreover, significant improvements were noted in the single support time on the affected side, backward walking 10ft, and side stepping 10ft on the affected side of the GM state compared to the PT state (p < .05). There were significant improvements in the stride length on the affected side and side stepping 10ft on the unaffected side of the PT state compared to the GM state (p < .05). CONCLUSION: FES is effective in improving the temporal-spatial gait and activities of daily living in hemiplegic stroke patients.

Analysis of the Interaction Between Side Jet and Supersonic Free Stream Using K-factor (상호 작용 계수를 이용한 측추력 제트와 초음속 자유류 상호 작용에 관한 연구)

  • Kim, Min-Gyu;Lee, Kwang-Seop
    • Journal of the Korea Institute of Military Science and Technology
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    • 제15권1호
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    • pp.101-110
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    • 2012
  • The side jet effects between jet flow and free-stream on a missile body were investigated by experimentally and numerically for modeling aerodynamic coefficients in pitch plane. K-factors for normal force and pitching moment were introduced to estimate the side jet effects. The main parameters of the jet interaction phenomena were angle of attack, jet pressure ratio, Mach number and jet bank angle. The K-factors for normal force coefficient and pitching moment coefficients in pitch plane were analysed.