• Clinical and Experimental Reproductive Medicine
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• 제30권3호
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• pp.241-248
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• 2003

Objective: The purpose of this study was to evaluate the survival rate of vitrified blastocyst according to the freezing vessels, equilibration time in cryoprotectant and artificial dehydration method. Methods: Human blastocysts were vitrified after loading onto the plastic straw, open-pulled straw (OPS), electron microscopy grid (EM grid) for 1.5 min or 3 min. They also were directly plunged into LN2 within 30sec. For artificial shrinkage of blastocysts, 36 gauge fine needle was pushed at the cellular junction of the trophectoderm into the blstocoele cavity until it shrank without damage of inner cell mass. Results: The survival rate of vitrified blastocysts on plastic straw, OPS, EM grid as freezing vessels were 26.7, 13.0 and 60.5%, respectively. The survival rate of EM grid was significantly higher than that of plastic straw and OPS (p<0.05). For 1.5 min equilibrium, the survival rates of early blastocyst (EB), middle blastocyst (MB) and late blastocyst (LB) were 64.4, 81.0, and 20.0% respectively. For 3 min equilibrium, the survival rates of EB, MB, and LB were 69.9, 50.0 and 57.5% respectively. The survival rates of EB and MB were significantly higher than that of LB in 1.5 min equilibrium group (p<0.05), however, the significance was not observed in 3 min equilibrium groups. In cytoplasmic shrinkage before vitrification, the survival rates of EB, MB and LB were 92.9, 100 and 75.9% respectively. The survival rate of MB was significantly higher than that of LB (p<0.05). The survival rates of vitrified blastocysts by artificial dehydration and slow-frozen blastocysts were not significantly different as 88.9 and 66.7%, respectively. Conclusion: This study showed that the vitrification of human blastocysts using EM grid and artificial dehydration is an effective method. Therefore, these methods would be an useful techniques for blastocyst cryopreservation.

• 한국산림과학회지
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• 제37권1호
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• pp.17-30
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• 1978

이태리포푸라재(材)의 건조(乾燥)의 한 방안(方案)으로서 열판건조(熱板乾燥)를 실시(實施)하여 건조중(乾燥中) 판재(板材)의 내부온도(內部溫度), 판재(板材)의 내부온도별(內部溫度別)에 따른 판재(板材)두께, 초기함수율(初期含水率), 말기함수율(末期含水率)과 건조시간(乾燥時間)의 관계(關係), 건조중(乾燥中) 함수율(含水率)과 건조속도(乾燥速度), 수축율(收縮率)과 복원율(復元率), 그리고 열판건조재(熱板乾燥材)의 생재비중(生材比重), 평형함수율(平衡含水率), 경단방향(徑斷方向) 전수축율(全收縮率) 등(等)을 조사(調査)하고 그 결과(結果)를 요약(要約)하면 다음과 같다. 1. 판재(板材)의 내부온도(內部溫度)는 건조초기(乾燥初期)에 급격히 상승(上昇)해서 15분(分) 동안 거의 일정(一定)하게 유지된 다음 서서히 상승(上昇)하였다. plateau temperature는 $114{\sim}119^{\circ}C$이었다. 2. 판재(板材)의 내부온도별(內部溫度別)에 있어서 판재(板材)의 건조시간(乾燥時間)(y)와 판재(板材)두께($x_1$), 초기함수율(初期含水率)($x_2$), 말기함수율(末期含水率)($x_3$) 사이에 관계식(關係式)은 다음과 같다. 3. 열판건조(熱板乾燥)의 건조시간(乾燥時間)(t)에 대(對)한 건조중(乾燥中) 함수율(含水率)(u)의 관계(關係)는 log u=4.658-0.060t(R=-0.990)이고, 건조속도(乾燥速度)(r)의 관계(關係)는 log r= -2.797-0.049t(R= -0.992)의 곡선(曲線)으로 각각(各各) 나타났다. 그리고 천연건조중(天然乾燥中) 함수율(含水率)과 건조속도(乾燥速度)는 그림 2 와 같다. 4. 열판건조중(熱板乾燥中) 건조시간(乾燥時間)(t) 에 대(對)한 판재(板材)두께 (y) 수축율(收縮率)의 관계(關係)는 log y= l.933+038t(R=0.927)이고, 판재복(板材福) 팽창율(膨脹率)(y)의 관계(關係)는 $y=-0.692+0.043t-0.001t^2(R=0.984)$의 곡선(曲綠)으로 각각(各各) 나타났다. 5. 말기함수율(末期含水率) 2%까지 건조시(乾燥時)에 열판(熱板)의 압력별(壓力別) 따른 두께 수축율(收縮率)은 압력(壓力) 높아질 수록 커졌으나 폭수축율(幅收縮率)과 두께 복원율(復元率)은 35psi에서 가장 컸다. 6. 열판건조재(熱板乾燥材)의 생재비중(生材比重)은 천연건조재(天然乾燥材)의 것보다 25% 증가하였으며, 평형함수율(平衡含水率)은 24% 감소하였고, 열판건조재(熱板乾燥材)의 항수축율(抗收縮率)은 27.7%이었다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2008년도 하계종합학술대회
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• pp.495-496
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• 2008

The magnetic characteristics of Mg-Zn ferrite that was fired at $1150^{\circ}C$ for 1hour and sintered at $1250^{\circ}C$ for 3hours was examined. The composition ratio of the ferrite was changed after sintering. In that case the composition ratio of ${Fe_2}{O_3}$ was increased but that of CuO was decreased. When the addition quantity of CuO was 3.8 mole%, it's shrinkage rate had maximum value. Magnetic permeability was decreased as the addition rate of CuO was increased and MgO was decreased. When the composition rate of CuO was 2.3 mol% and MgO was 10.9 mol%, the firing density had maximum value. In case that CuO was 2.8mol% and MgO was 10.4mol%, PL had minimum value.

• 한국염색가공학회지
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• 제8권4호
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• pp.42-51
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• 1996

Alkaline hydrolysis to improve the hand of PET/acetate union fabric was studied in relation to skin saponification and retarding effect of salts on the alkaline hydrolysis of cellulose acetate fiber, accelerating effect of salts on the alkaline hydrolysis of PET fiber, and changes of total hand value(T.H.V) of PET/acetate union fabric treated with alkali/salt solution. It was found that the rate of saponification of acetate was delayed by the addition of salts such as LiCl, NaCl and CH$_{3}$COONa into NaOH solution below 10 minutes. The rate of shrinkage of acetate fabric treated with 5g/l NaOH solution at 9$0^{\circ}C$ and 60 minutes showed 20 % but it was decreased 8% by. the addition of 120g/l Concentration of inorganic salts. We could know that the rate of alkaline hydrolysis of filament yarn treated with alkali solution at 9$0^{\circ}C$ and 60 minutes was delayed about 3 % using 2,000T/M of hard twist yarn, especially acetate filament treated with alkali solution at 9$0^{\circ}C$ and 10 minutes was delayed about 10%. T.H.V. of PET/acetate union fabric was increased from 2.77 to 3.04~3.18 by the addition of salts into alkali solution.

• 한국재료학회지
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• 제3권3호
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• pp.276-281
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• 1993

3원계 U-Ce-O산화물의 소결거동을 연구하기 위하여 $UO_2$ 및 $CeO_2$분말을 ball-mill 방법으로 혼합한 (U, Ce)$O_2$의 영향이고, 나중에 나타나는 극대점은 $CeO_2$의 영향 때문이다. 또한 $Ceo_{2}$함량이 증가할수록 소결이 지연됨을 알수 있었다. 동일한 10wt. % $CeO_2$함량에서, 4시간동안 ball-milling을 하였을때가 소결속도는 가장 빨랐다.

• Journal of the Korean Wood Science and Technology
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• 제25권4호
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• pp.99-107
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• 1997

This study was executed to test the possibility of replacement for domestic Japanese larch(Larix leptolepis) for hardwoods and to acquire the information about the effects of drying temperature on internal temperature, moisture content and drying defects. In high-temperature drying, internal temperature increased rapidly to boiling point, immediately after that point the internal temperature rising rate was reduced. In the case of drying at temperature of $125^{\circ}C$, internal temperature could reach at boiling point in a very short time. Moisture content in high-temperature drying showed constant drying rate period and first period of falling rate drying together in 4 hours since experiment begun. There was no strong correlation between initial moisture content and final moisture content. Average drying rate at $115^{\circ}C$, $120^{\circ}C$ and $125^{\circ}C$ was 1.42%/hr, 1.88%/hr and 2.02%/hr, respectively; the case of drying temperature of $125^{\circ}C$ showed most rapid drying rate. Drying rate of $125^{\circ}C$ was so rapid that it showed more severe shrinkage, bow, collapse, end check, and internal check development than in other drying conditions. The result of this study showed the strong possibility of high-temperature drying for Japanese larch, and to dry Japanese larch optimally, dry bulb temperature should not exceed $120^{\circ}C$.

• 한국연소학회지
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• 제19권2호
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• pp.8-14
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• 2014

Experiments were conducted to clarify role of the outermost edge flame on low-strain-rate flame extinction in buoyancy-suppressed non-premixed methane flames diluted with He and $N_2$. The use of He curtain flow produced a microgravity level of $10^{-2}-10^{-3}g$ in $N_2$- and He-diluted non-premixed counterflow flame experiments. The critical He and $N_2$ mole fractions at extinction with a global strain rate were examined at various burner diameters (10, 20, and 25 mm). The results showed that the extinction curves differed appreciably with burner diameter. Before the turning point along the extinction curve, low-strain-rate flames were extinguished via shrinkage of the outermost edge flame with and without self-excitation. High-strain-rate flames were extinguished via a flame hole while the outermost edge flame was stationary. These characteristics could be identified by the behavior of the outermost edge flame. The results also showed that the outermost edge flame was not influenced by radiative heat loss but by convective heat addition and conductive heat losses to the ambient He curtain flow. The numerical results were discussed in detail. The self-excitation before the extinction of a low-strain-rate flame was well described by a dependency of the Strouhal number on global strain rate and normalized nozzle exit velocity.

• 한국건축시공학회지
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• 제17권2호
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• pp.141-147
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• 2017

본 연구는 기존의 에폭시 수지 충전 접착재의 단점을 보완한 마그네시아 실리케이트 인산염을 활용한 무기충전 접착재 개발 연구로서 사소마그네시아와 플라이애시를 기반으로 제1인산칼륨과 붕사를 사용하여 가사시간을 조절한 무기충전 접착재를 개발하고자 하였다. 이를 위하여 먼저 제1인산칼륨의 적정 첨가율을 도출하기 위한 기초실험을 실시하였다. 기초 실험을 바탕으로 적정강도를 취하면서 접착재 위로 인산염 잔존물이 떠오르지 않게 한 적정 첨가율을 도출하였으며, 이후 붕사 첨가율에 따라 본 실험을 실시하였고, 제조된 접착재를 대상으로 가사시간, 휨강도, 압축강도, 접착강도, 인장강도, 가열변화율, 경화수축률, 라돈가스 및 포름알데히드 방출량을 측정하였다. 그 결과 제1인산칼륨의 적정 첨가율은 35%이며, 가사시간 조절을 위해 붕사 첨가율에 따른 가사시간은 약 10분, 15분, 25분으로 나타났다. 휨강도 및 압축강도는 12시간 최소 휨강도 8.0MPa, 최소 압축강도 31.0MPa로 나타났다. 인장강도는 최소 4.1MPa로 나타났으며, 경화수축률은 최대 2.4%, 가열변화율은 최대 -0.3%로 'KS F 4923'(콘크리트 구조물 보수용 에폭시 수지)의 품질기준에 모두 만족하였다. 라돈가스 및 포름알데히드 방출량의 경우 모두 방출량이 검출되지 않았다. 따라서, 마그네시아 실리케이트 인산염을 활용한 무기충전 접착재의 가사시간에 따른 발열시간을 조절한다면 보다 시공성과 안전성을 확보한 무기 충전 접착재를 제조 할 수 있을 것으로 판단된다.

• 콘크리트학회논문집
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• 제15권2호
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• pp.280-287
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• 2003

산업폐기물 중 하나인 굴패각(Oyster Shell, OS)에 대한 건설재료로써의 활용성을 검토하기 위해 굴패각을 혼합한 콘크리트의 장기역학적 특성과 내구성을 실험적으로 평가하였다. 실험결과에 따르면 굴패각을 10% 대체한 콘크리트의 장기강도는 굴패각을 대체하지 않은 콘크리트와 유사한 결과를 보였으나, 굴패각을 20% 대체한 콘크리트의 장기강도는 감소하는 것을 보였다. 즉, 일정 한도 이상의 굴패각 대체는 콘크리트의 장기재령 강도에 열화요인으로 작용할 수 있는 것으로 나타났고, 굴패각의 대체에 따른 탄성계수 저하는 대체율에 거의 비례적으로 저하하였으며 굴패각의 대체율 20%에서 약 10∼15% 저하하였다. 굴패각의 대체율이 증가할수록 건조수축 발생량은 증가하였으며 기존의 건조수축과 크리프 모델식은 굴패각의 증가에 따른 영향을 잘 반영하지 못하였고 이에 대한 예측식의 보정이 필요하다. 잔골재의 일부를 굴패각으로 대체하여도 콘크리트의 동결융해 저항성, 탄산화 저항성, 및 화학침식 저항성에는 나쁜 영향을 미치지 않으며, 투수 저항성은 오히려 크게 개선되었다.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.315-320
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• 2015

Background: The efficacy of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy can be measured based on the rate of treatment response, based on the Response Evaluation Criteria in Solid Tumors (RECIST) criteria or progression-free survival (PFS). However, there are some patients harboring sensitive EGFR mutations who responded poorly to EGFR-TKI therapy. In addition, there is variability in the PFS after EGFR-TKI treatment. Methods: We performed a retrospective analysis of the medical records of 85 patients with non-small cell lung cancer, who had achieved a stable disease or better response at the first evaluation of treatment response, after receiving a 2-month course of gefitinib. We calculated the tumor shrinkage rate (TSR) by measuring the longest and perpendicular diameter of the main mass on computed tomography before, and 2 months after, gefitinib therapy. Results: There was a significant positive correlation between the TSR and PFS (R=0.373, p=0.010). In addition, a simple linear regression analysis showed that the TSR might be an indicator for the PFS ($B{\pm}standard$ error, $244.54{\pm}66.79$; p=0.001). On univariate analysis, the sex, histologic type, smoking history and the number of prior chemotherapy regimens, were significant prognostic factors. On multivariate regression analysis, both the TSR (${\beta}$=0.257, p=0.029) and adenocarcinoma (${\beta}$=0.323, p=0.005) were independent prognostic factors for PFS. Conclusion: Our results showed that the TSR might be an early prognostic indicator for PFS in patients receiving EGFRTKI therapy.