• Journal of Korean Neurosurgical Society
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• 제65권2호
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• pp.224-235
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• 2022

Objective : Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, neurointerventionists have been increasingly concerned regarding the prevention of infection and time delay in performing emergency thrombectomy procedures in patients with acute stroke. This study aimed to analyze the effects of changes in mechanical thrombectomy protocol before and after the COVID-19 pandemic on procedure time and patient outcomes and to identify factors that significantly impact procedure time. Methods : The last-normal-to-door, first-abnormal-to-door, door-to-imaging, door-to-puncture, and puncture-to-recanalization times of 88 patients (45 treated with conventional pre-COVID-19 protocol and 43 with COVID-19 protection protocol) were retrospectively analyzed. The recanalization time, success rate of mechanical thrombectomy, and modified Rankin score of patients at discharge were assessed. A multivariate analysis was conducted to identify variables that significantly influenced the time delay in the door-to-puncture time and total procedure time. Results : The door-to-imaging time significantly increased under the COVID-19 protection protocol (p=0.0257) compared to that with the conventional pre-COVID-19 protocol. This increase was even more pronounced in patients who were suspected to be COVID-19-positive than in those who were negative. The door-to-puncture time showed no statistical difference between the conventional and COVID-19 protocol groups (p=0.5042). However, in the multivariate analysis, the last-normal-to-door time and door-to-imaging time were shown to affect the door-to-puncture time (p=0.0068 and 0.0097). The total procedure time was affected by the occlusion site, last-normal-to-door time, door-to-imaging time, and type of anesthesia (p=0.0001, 0.0231, 0.0103, and 0.0207, respectively). Conclusion : The COVID-19 protection protocol significantly impacted the door-to-imaging time. Shortening the door-to-imaging time and performing the procedure under local anesthesia, if possible, may be required to reduce the door-to-puncture and door-to-recanalization times. The effect of various aspects of the protection protocol on emergency thrombectomy should be further studied.

• 대한화상학회지
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• 제23권2호
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• pp.54-59
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• 2020

Purpose: A fourth degree burn is a full-thickness burn of the skin usually accompanied by damage to deep structures and commonly results in extensive damage to surrounding tissues which makes the treatment of the wound difficult. Coverage of these wound using free flap is known to effective but not commonly used. The purpose of our study is to review our experience and suggest early application of free flap surgery. Methods: A retrospective review was performed from 2010 to 2019, on a total of 34 fourth degree burn patients undergone free flap surgery as primary treatment in our hospital. We reviewed the location of the injury, etiology, TBSA (%), Presence of osteomyelitis, flap choice, complications, period of injury to surgery and healing. Results: Using free flap as a primary reconstrcuction, the outcome is satisfactory. The treatment period was shortened, and there was less loss of function due to complications. Also the incidence of osteomyelitis and amputation was significantly low. Conclusion: Applying free flap surgery as soon as possible in fourth degree burns is effective, such as reducing complications such as infection, reducing amputation, shortening treatment period, and preventing severe sequelae.

• 지질공학
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• 제32권4호
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• pp.467-482
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• 2022

The Yeonghae basin is located at the northeastern part of the Yangsan fault (YSF; a potentially active fault). The study of the architecture of the Yeonghae basin is important to understand the activity of the Yangsan fault system (YSFS) as well as the basin formation mechanism and the activity of the YSFS. For this study, Digital Elevation Model (DEM) was used to highlight the marginal faults, and structural fieldwork was performed to understand the geometry of the intra-basinal structures and the nature of the bounding faults. DEM analysis reveals that the eastern margin is bounded by the northern extension of the YSF whereas the western margin is bounded by two curvilinear sub-parallel faults; Baekseokri fault (BSF) and Gakri fault (GF). The field data indicate that the YSF is striking in the N-S direction, steeply dipping to the east, and experienced both sinistral and dextral strike-slip movements. Both the BSF and GF are characterized dominantly by an oblique right-lateral strike-slip movement. The stress indicators show that the maximum horizontal compressional stress was in NNE to NE and NNW-SSE, which is consistent with right-lateral and left-lateral movements of the YSFS, respectively. The plotted structural data show that the NE-SW is the predominant direction of the structural elements. This indicates that the basin and marginal faults are mainly controlled by the right-lateral strike-slip movements of the YSFS. Based on the structural architecture of the Yeonghae basin, the study area represents a contractional zone rather than an extensional zone in the present time. We proposed two models to explain the opening and developing mechanism of the Yeonghae basin. The first model is that the basin developed as an extensional pull-apart basin during the left-lateral movement of the YSF, which has been reactivated by tectonic inversion. In the second model, the basin was developed as an extensional zone at a dilational quadrant of an old tip zone of the northern segment of the YSF during the right-lateral movement stage. Later on, the basin has undergone a shortening stage due to the closing of the East Sea. The second model is supported by the major trend of the collected structural data, indicating predominant right-lateral movement. This study enables us to classify the Yeonghae basin as an inverted strike-slip basin. Moreover, two opposite strike-slip movement senses along the eastern marginal fault indicate multiple deformation stages along the Yangsan fault system developed along the eastern margin of the Korean peninsula.

• 한국버섯학회지
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• 제20권2호
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• pp.69-77
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• 2022

기존에 사용되는 1차 봉지배양 및 2차 매트생산 배양에 소요되는 기간을 단축시키기 위해 시루송편버섯 균사체에 Co-60 저준위 감마선 200 Gy 24시간 조사로 돌연변이 시킨 ToM 균사체를 활용하여 봉지배양이 생략된 박스 배양법을 시도하였다. 또한, 매트의 품질 및 물성을 강화시키기 위해 균액으로 ammonium nitrate가 3 g/L첨가된 mYMB6을 사용하였고, CaCO₃를 1.5% 함유한 톱밥배지에서 균일한 품질의 균사체 매트 생산이 가능하다는 점을 확인하였으며, 기간 또한 기존의 생산방법과 비교하여 10일 이상 단축할 수 있다. 본 결과는 균사체 기반 친환경 소재 연구에 활용할 수 있을 것으로 생각된다.

• 한국작물학회지
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• 제33권s01호
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• pp.86-97
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• 1988

Sesame(Sesamum indicum L.) is probably the most ancient oilseed crop known in the world. The seed of sesame is used in a variety of ways as food. The whole seed may be eaten raw, either roasted or parched, or fed to birds and stock. Sesame oil is used as a salad or cooking oil, in shortening, margarine and in the manufacture of soap. Minor uses are as a fixative in the perfume industry and formerly as a carrier for fatsoluble substances in pharmaceuticals such as penicillin. One of the minor constituents of sesame oil, sesamin, is used for its synergistic effect in pyrethrin insecticides, in addition of a small quantity of this substance markedly increases the effectiveness of fly sprays. The meal remaining after oil extraction can be used as and animal feed-stuff or as manure. In general sesame meal is considered to be equal to cottonseed or soybean meal as a protein supplement for livestock and poultry. It is especially high in certain amino-acids such as methionine, which is low in soybean meal, and thus can be combined with it or similar meal to form a more balanced ration. An attempt to summarize the literature review on quality improvement of sesame was made to discuss the accomplishments of the past and perspectives in the future. The reviews on quality improvement of sesame were mainly discussed in connection with the cultural practices and genetic informations in current status. The emphasis focussed on environmental variation of quality in cultural practices, such as harvest time, variety by location, climatic condition, fertilizer application, and growth regulator treatment. On the genetic variation of quality, it was discussed on variety background, mutation breeding, correlations, and inheritance of quality related characteristics. It also was discussed on relationship between quality and plant traits, storage condition or period, and seed coat color. Moreover, current research status were reviewed on some minor elements such as sesamin, oxalic acid, and trypsin inhibitor. As a results of the review, the lack of an effort to quality improvement in each utilization area was indicated as a problem area. More active efforts for the improvement of quality were also insufficient to incorporate the available genes for quality in breeding method or collection and analysis of breeding materials. Therefore, researches in the future would be recommended to emphasize on these problem areas.

• 생물환경조절학회지
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• 제32권1호
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• pp.15-22
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• 2023

장미는 전세계적으로 가장 많이 생산되는 화종 중 하나로, 절화 장미는 시설 내부에서 연중 생산된다. 최근 여름철 시설 내부 온도 상승으로 인해 절화장 단축 등 절화 장미의 품질 저하가 심각하게 발생하고 있다. 본 연구는 계절별 절화 품질 및 수량을 비교하여 여름철 생산된 절화 장미의 품질 특성을 파악하고, 고온기 야간 냉방을 통한 온도 하강 효과와 여름철 절화 품질 개선 효과를 검정하고자 수행하였다. 'Pink Beauty'은 여름철 절화장, 화수장, 경경, 화수경경, 화폭, 생체중 등이 통계적으로 유의하게 저하되었으며, 'Pink Shine'은 여름철 절화장, 경경, 화폭 및 화고, 생체중이 통계적으로 유의하게 저하되었다. 고온기 야간 냉방을 수행한 결과, 7-8월 온실 내부 평균 온도는 약 2.5℃ 저하되었으며, 배지 평균 온도는 약 3.0℃ 감소되었다. 고온기 야간 냉방 시 절화 품질 및 수량을 비교한 결과 세 품종 모두 야간 냉방 시 절화장, 생체중, 경경 등 절화 품질이 향상되었다. 이를 통해 고온기 야간 냉방이 여름철 절화 장미의 품질 저하 문제 해결에 도움이 될 것으로 기대된다.

• 한국작물학회지
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• 제30권4호
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• pp.359-367
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• 1985

본 시험은 산간부인 진안(해발 303 m)에서 생식생장기에 일반상수를 대비하여 냉수를 유수형성기와 감수분열기에 4, 8, 12 일간 관개하였을때 야기되는 물질생산 및 수용계의 냉해반응을 알고자 수행하였던 바 다음과 같은 결과를 얻었다. 1. 냉수관개기간이 길어질수록 간장, 수장, 추출도의 신장이 억제되었으며, 유수형성기 냉수관개는 하위절, 감수분열기 냉수관개는 상위절의 절간신장을 단축시켰다. 또한 지경 및 영화의 퇴화는 유수형성기 냉수 관개에 민감한 영향을 받아 2차지경과 영화의 분화착생수 감소 및 퇴화의 증가를 보였다. 2. 불임율과 등숙장해도 냉수관개기간이 길어질수록 심하였고 유수형성기보다 감수분열기 냉수관개에서 피해율이 현저히 높았는데 특히 피해반응이 예민한 시기는 영화원기분화기와 감수분열기경이었으며 불임율, 등숙비율과 수량과는 유의적인 상관관계를 보였다. 3. Source와 Sink 관련형질중 지경과 영화의 퇴화는 엽면적에 영향을 받고 불임율과 수량은 간장, 수장,추출도의 신장량과 상관이 있었다.

• 대한한의학방제학회지
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• 제31권3호
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• pp.157-169
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• 2023

Gracilaria Verrucosa (GV), a seaweed used in traditional Korean medicine, was studied for its effects on MI-induced heart failure in rats. MI is caused by a blocked coronary artery, leading to severe cardiac dysfunction. The study used a rat model to assess cardiac changes over time and evaluate the impact of GV on heart failure. Ischemia was induced through LAD ligation surgery, and the extent of ischemic area was measured as a prognostic factor. GV extract administration significantly improved cardiac morphology and reduced cardiac weight compared to the MI group. GV treatment also improved cardiac function, as evidenced by positive effects on chamber dilation during MI-induced heart failure. Parameters such as ejection fraction (EF) and fractional shortening (FS) were measured. The MI group showed decreased EF and FS compared to the sham group, while these parameters improved in the GV group. GV treatment also reduced levels of LDH, CPK, and CK-MB in the serum, indicating reduced myocardial damage. Histological analysis revealed that GV treatment attenuated cardiac hypertrophy and fibrosis, with reduced collagen deposition in the myocardium. Immunohistochemistry analysis showed suppressed expression of TGF-β1 and collagen 1, involved in fibrosis. In conclusion, GV showed potential in improving cardiac function in a rat model of MI-induced heart failure. It alleviated myocardial damage, attenuated cardiac hypertrophy and fibrosis, and suppressed fibrotic markers. Further studies are needed to explore its clinical efficacy and underlying mechanisms in cardiac diseases beyond animal models.

• 융합정보논문지
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• 제12권3호
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• pp.186-192
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• 2022

본 연구는 U대학교 LINC+ 사업을 통한 교육과정 개발 및 교육환경 개선이 직무교육훈련에 미치는 영향을 확인하고자 협약산업체 110곳을 대상으로 조사하였다. 연구결과, 핵심역량과 직무역량은 현장실습과 교육환경에서 각 5.73점으로 나타났고, 직무성과는 OJT 5.58점, 교육환경이 5.74점으로 유의하였다(p<0.05). 교육과정의 적합성 및 교육환경과 채용성과의 관련성은 OJT 5.73점, 교육훈련기간에서 현장실습 5.74점, 교육환경 5.79점, 직무재교육/교육훈련비에서는 OJT 5.73점, 교육환경 5.79점으로 유의하였다(p<0.05). 또, 산업체 응답자의 86.3%에서 LINC+사업 교육과정 이수학생에서 1~6개월 직무기간이 단축되었고, 신입사원 교육비가 절감되었다고 응답하였다. 따라서, U대학교 LINC+사업은 산업체의 요구를 반영한 교육과정 운영과 산업체 현장과 동일한 교육환경 개선으로 직무적응기간 단축과 신입사원 교육비 절감효과를 확인할 수 있었다.

• 한국건축시공학회지
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• 제23권4호
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• pp.465-476
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• 2023

공동주택 지하층 공사시 발생하는 생산성 저하 문제를 해결하기 위한 개선책으로 필요한 PC 더블월(Double Wall) 공법을 개발하였다. 개발 공법은 기존의 PC 더블월 공법과 차별화되어, 지하 주동부의 다양한 PC 형상에 대응할 수 있고, 수평 및 수직 재하 등 부담 하중의 축력비에 충분히 견딜 수 있는 구조적으로 안전한 PC 더블월 공법으로서, 현장 테스트베드를 통하여 설계 및 제작기술, 그리고 시공기술의 적용성 분석하고 개발 공법의 실물 사이즈에 대한 목업테스트를 통해 품질성능을 검토하였다. 목업 테스트 수행 결과, PC 더블월의 기립 설치 및 내부 채움 콘크리트 타설시 균열이나 변형은 관측되지 않아, 구조적으로 안전한 것으로 나타났으며, 내부 채움 콘크리트는 양호한 품질 상태를 유지하였다. 복합적인 요인으로 인해 개발 공법을 실제 APT 주동부 지하층에 적용하지 못해 개발공법의 시공성 분석은 개발 자료를 기반으로한 설치 전문가들의 인터뷰를 통해 분석하였다. 개발 디테일을 적용하여 PC 더블월을 두가지 폭(W=2.4m, W=3.2m)으로 제작하여 설치하는 경우에 대해 PC 부재 설치 전문가 3명과 인터뷰를 수행하였다. 재래식 현장 타설 공법이 통상 47일/층~68일/층 소요되는 데 반해, 제안공법을 적용하면 공기일수가 20일/층~29일/층 소요되는 것으로 나타나, 공기단축 측면에서 효과가 큰 것으로 나타났다. 추후 연구 수행 방향으로서, 실제 APT 주동부 지하층에 적용하여, 시공상 관리 이슈를 추가적으로 도출하고, 공기단축 및 품질 유지에 대한 결과를 검증할 예정이다.