• Plant Resources
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• v.6 no.1
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• pp.81-88
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• 2003

Higenamine [1-(4-hydroxy-6, 7-dihydroxy-l, 2, 3, 4-tetrahydroisoquinoline) is a cardiotonic constituent of Aconiti tuber, one of the most widely prescribed oriental medicines. S-(-)higenamine was reported to have a stronger cardiotonic activity than R-(+)-higenamine and known as a central intermediate in the biosynthesis of various benzyl isoquionoline alkaloids in plants. The separation of higenamine enantiomers has been accomplished with capillary electrophoresis using cyclodextrins (CDs) as chiral selectors. Good resolution of this enantiomers was obtained using a 50 mM sodium phosphate buffer containing hydroxypropyl $\beta$-CDs using 27 cm fused silica capillary (50${\mu}{\textrm}{m}$ i.d., 20 cm to detector) at 25 $^{\circ}C$. With the electric field of 340 V/cm, the separation time of higenamine enantiomers was less than 6 min. Under this optimum conditions, the relative standard deviations of migration time and peak area were less than 1.6% and 3.2%. A 512-channel diode array detector was confirmed for the higenamine. The detection limits (S/N = 3) of these enantiomers are $1.5mutextrm{m}$/mL. We confirmed the chiral form of higenamine in medicinal plants.

• Korean Journal of Remote Sensing
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• v.22 no.2
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• pp.131-139
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• 2006

IKONOS images have the perspective geometry in CCD sensor line like aerial images with central perspective geometry. So the occlusion by buildings, terrain or other objects exist in the image. It is difficult to detect the occlusion with RPCs(rational polynomial coefficients) for ortho-rectification of image. Therefore, in this study, we detected the occlusion areas in IKONOS images using the nominal collection elevation/azimuth angle and restored the hidden areas using another stereo images, from which the rue ortho image could be produced. The algorithm's validity was evaluated using the geometric accuracy of the generated ortho image.

• Nuclear Engineering and Technology
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• v.34 no.1
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• pp.30-41
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• 2002

The neutron beam is fully characterized for the prompt gamma activation analysis facility at Hanaro in the Korea Atomic Energy Research Institute(KAERI). The facility uses thermal neutrons which are diffracted vertically from a horizontal beam port by a set of pyrolytic graphite(PG) crystals positioned at the Bragg angle of 45" Neutron spectra, neutron flux and Cd-ratio are determined for the three extraction modes of diffracted beam by means of the theoretical and experimental efforts. To obtain theoretical result, the reflectivity of pyrolytic graphite is calculated in the diffraction model for mosaic crystal and the angular divergence after diffraction by mosaic crystal is estimated from Monte Carlo simulation. The time-of-flight spectrometer and gold activation wire are used for measuring the neutron spectra. Both the calculated and measured spectra have proven that the unique feature of polychromatic beam obtained by PG crystals are useful for PGAA. The thermal neutron flux of 7.9$\times$107 n/cm$^2$s and the Cd-ratio of 266 for gold have been achieved at the sample position while the reactor operates at 24 MW The uniformity of beam flux is 12% in the central 1$\times$1 cm$^2$ area. Finally, the beam is briefly characterized by the effective velocity and temperature which are determined by measuring the prompt Y-ray spectra for thin and thick boron samples.ples.

• Archives of Pharmacal Research
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• v.11 no.2
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• pp.134-138
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• 1988

Urine measurements by MNR were made for 25 persons including cancer and non-cancer patients. The aromatic proton signals of NMR wer observed much more often in cancer patients' urine than non-cancer patients' one. To compare the amount of the phenolic compounds excreted in urine between cancer and non-cancer patient, urine analysis by HPLC with UV detector was performed. Total peak area and major peak areas of cancer patients' urine wer emuch greater than those of non-cancer patients' one. To check the phenolic compound excreted in urine, a new jellied reagent named Gift reagent which was based on Millon's reagent, was developed for urine color reaction. When the reagent was tested, the sensitivity and specificity for urine samples of 69 persons including cancer and non-cancer patients were measured by 85.3% and 91.4%, respectively, indicating that the Gift reagent afford a possibility of cancer diagnosis.

• Journal of the Korean Geographical Society
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• v.30 no.1
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• pp.35-56
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• 1995

During the last two decades, Korea has achieved remarkable economic growth. In this process the nation has become urbanized and industrialized. But we have also encountered widening regional disparity, housing shortage of larger cities, transportation congestion, environmental pollution and many other problems. Rapid increasing urbanization and continuous migration toward Seoul since the late 1960s have been one of the major concerns of government. Government has sought ways to moderate the population increase in Seoul. The regulation which include new town development near Seoul and dispersion strategies of higher education and other administration and living facilities outside of Seoul havemade a great expansion of the spatial influence of Seoul city. Seoul metropolitan reaion has evolved as the most powerful center of political and economical spaces. Generally within a metropolitan region, there exists a growing mutual interdependence economically, as well as socially between a central city and its surrounding area. Seoul metropolitan region manifests itself not only as a coherent system of urbanized regions, but also as an integral part of the daily urban system. The surrounding Gyunggi province and Seoul city become closely linked both economically and functionally, constituting true functlonai urban system. This study is primarily undertaken with the purpose of delineation of the sphere of influence of Seoul city in 1990. At the time of 1985, Seoul metropolitan region was delineated according to the result of the study which was performed by Korea Research Institute for Human Settlements. Afterward, the rapid speed of metropolitanization process with dramatic increase in mobility through the provision of wider transportation system across the Capital region have evolved, resulting in the great expansion of the spatial influence of Seoul city. So this study examines the expanded area of Seoul metropolitan regin during the period of 1985-90. In order to delineate Seoul metropolitan region, the indices of urbanization and functional linkage are selected. Variables included in the measurement of the urbanization level are agricultural structure, population characteristics, manufacturing and service industries, and cultural aspects such as newspaper circulation, the ratio of car ownership and piped water supply. Variables included in the measurement of functional linkage are commuting, shopping pattern, centralized service such as medical facilities and trade of agricultural products. The standardization method and factor analysis are employed in making the delineation of Seoul metropolitan region. According to the result of this study, 2 cities, 8 Eups and 46 Myuns are included Seoul metropolitan region in 1990. If we compare this delineated area in 1990 to that of 1985, we can find the distinctive pattern of expanded axes according to the main transportation routes such as Seoul-Suweon, Seoul-Gwangju, Seoul-Incheon. In 199O, all the Gyunggi province, except a few Myuns located at the north and northwest part of Gyunggi province, are included in Seoul metropolitan region. Furthermore, this study attempts to the analysis of regional structure of Seoul metropolitan region according to the functional characteristics of each city and Gun. Variables included in this analysis are the new residential function, manufacturing function, service function, education and infermation function, public facility function and agricultural function. Factor analysis and cluster analysis are employed in making regionalization. Seoul metropolitan reaion is subdivided into four subregions which reflect different functional specialization. The first group is the specialized region of newly formed residential function. The second group is the specialized reaion of manufacturing function. The third group is the specialized region of service function. And the fourth group has little specialized in terms of manufacturing, service, and residential function. But this region has some potentiality of development when Seoul metropolitan region grow continuously. Seoul metropolitan region accounted for 43% of national population, despite 11.8% of national land size in 1990. Although Seoul metropolitan region enjoys important agglomeration economies, it also has huge social cost in the form of transportation congestion, housing shortage, rapid increase of land value, environment pollution, and etc. Efficient metropolitan plan making is a vital element in promoting Seoul's economic development and providing high quality living environment at low cost. In the light of the result of this study, the outer ring of Seoul metropolitan region, especially northeastern part, are underdeveloped compared to overdeveloped southwestern area. It is needed to develop the guidelines for the implement of the growth control and management plan, inducing more balanced development for whole Seoul metropolitan reaion.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.464-480
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• 2012

This paper includes consideration for construction of Sejong City and seeking its alternative. Korean government has gone ahead with the relocation of 35 ministries of central government from Seoul metropolitan area to Sejong city for balanced regional development. But many specialists are worried about the spatial division of government function because such a spatial division would bring down the functional efficiency of central government. This paper proposes to make Sejong city the administrative capital city instead of the relocation of some ministries to Sejong city, and discusses the necessity and appropriateness to develop Sejong city as an administrative capital city.

• Journal of the Korean Society of Safety
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• v.27 no.6
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• pp.70-77
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• 2012

Experimental investigations were performed to examine the characteristics of propagating flame fronts around multiple bars within a rectangular chamber. The explosion chamber is 400 mm in height, $700{\times}700mm^2$ in cross-section and has a large top-venting area, $A_v$, of $700{\times}210mm^2$. This results in a value of 0.44 for $A_v/V^{2/3}$ and a L/D value of 0.57. The multiple obstacles of length 700 mm with a blockage ratio of 30 % were placed within the chamber. Temporally resolved flame front images were recorded by a high speed video camera to investigate the interaction between the propagating flame and the obstacles. Results showed that the flame propagation speeds before the flame impinges onto the obstacle almost equal to the laminar burning velocity. As the propagating flame impinged on the obstacle, the central region of flame began to become concave, this resulted in the flame deceleration in the region. As the flame interacted with the modified flow filed generated behind the central obstacle, the probability density functions(PDFs) of the local flame displacement speed were extensively distributed toward higher speeds.

• Anxiety and mood
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• v.17 no.2
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• pp.84-91
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• 2021

Objective : Mismatch negativity (MMN) is known to reflect several abnormalities of cognitive functioning. This study is aimed to investigate the differences in MMN among major depressive disorder (MDD) patients with or without suicidal ideation. Methods : Sixty-seven patients with MDD were recruited into this study. MMN was measured by a 64-channel electroencephalography (EEG) using oddball paradigm over the front-central area. Clinical characteristics were assessed using the Beck Anxiety Inventory (BAI), the Beck Depression Inventory-II (BDI-II), and the Beck Scale for Suicide ideation (SSI-BECK). Patients were divided into two groups, no suicidal ideation (N=12) and suicidal ideation (N=55), depending on the presence of suicide ideation in SSI-BECK questionnaires. Results : The MMN latencies were significantly longer in the MDD patients with suicidal ideation than in the MDD patents without suicidal ideation (p<0.05). The MMN amplitudes were not significantly different between the two groups. Conclusion : Suicidal ideation may be associated with longer MMN latencies, and it suggests that MMN may play a potential role in assessing the suicidal risk among MDD patients.

• Journal of Korean Society of Transportation
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• v.24 no.1 s.87
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• pp.109-120
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• 2006

Since the 1st of July, 2004, the public transport system of the Seoul metropolitan area has been rearranged. In the new system, bus lines are divided into 4 classes-wide area, arterial road, branch, and rotation lines with renewed fare system based on the total distance travelled. Since central control center known as the Bus Management System (BMS) integrates the entire system operation. it now becomes feasible to collect travel information and provide it to the users scientifically and systematically. The Purpose of this study is to forecast transit travel time using real-time traffic data coming from both buses and subway. This is significant contribution since provision of real-time transit information and easy access to it would most likely boost the use of mass transit system, alleviating roadway congestion in the metropolitan area.

• Korean Journal of Plant Resources
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• v.8 no.2
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• pp.175-182
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• 1995

This study was carried out to investigate the check shelling distribution of Lindera erythrocarpa Makino in Kanghwa Island, MT. Suri, Kyunggido and MT. Kaya, Chungchongnamdo. The results were as follows : The total distribution area of Linedra erythrocarpa where are Jeondeung temple and Jugsu temple Kanghwa Island, MT. Suri, Kyunggido and MT. Kaya, Chungchongnamdo was 344.4ha and the total number of Linedra erythrocarpa was 3,224. The total number of femle Linedra erythrocarpa was625(22.2%) except the seedlings under 2cm of DBH(Diameter breast of height). For the estimation of tree age by counting of tree rings, the regression equation was Y=1.79X+9.47($R^2$=0.83, DBH=cm). The soil acidity of stands studied was $pH4.6{\sim}pH5.8$. And the soil acidity of Seoul was $pH4.2{\sim}pH4.5$ So for the Planting Linedra erythrocarpa in Seoul area, the soil acidity of planting area should be changed to $pH4.6{\sim}pH5.8$. The flower size of and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. The length of petiole of male and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. The length of petiole of male and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. And the number of flowers per flowering bud of male and female were 13.4, 11.2, respectively. The flowering period of Lindera erythrocarpa in Suwon was 21 days from May 2 to May 22. And The leaf continuing period of Lindera erythrocarpa in Suwon was 203 days from April 7 to October 27. And the fall-foliage color continuing period was 10 days from October 18 to October 27. The fruit continuing period of Lindera erythrocarpa in Suwon was 61 days from September 26 to November 26.