• 제목/요약/키워드: sensitivity and specificity

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의학적 의사결정 도구들에 대한 고찰 : Bayesian analysis and ROC analysis (Medical decision making tools : Bayesian analysis and ROC analysis)

  • 이병도
    • Imaging Science in Dentistry
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    • 제36권1호
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    • pp.1-5
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    • 2006
  • During the diagnostic process of the various oral and maxillofacial lesions, we should consider the following: 'When should we order diagnostic tests? What tests should be ordered? How should we interpret the results clinically? And how should we use this frequently imperfect information to make optimal medical decisions?' For the clinicians to make proper judgement, several decision making tools are suggested. This article discusses the concept of the diagnostic accuracy (sensitivity and specificity values) with several decision making tools such as decision matrix, ROC analysis and Bayesian analysis. The article also explain the introductory concept of ORAD program.

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Serodiagnosis of Extraintestinal Amebiasis: Retrospective Evaluation of the Diagnostic Performance of the Bordier® ELISA Kit

  • Beyls, Nicolas;Cognet, Odile;Stahl, Jean-Paul;Rogeaux, Olivier;Pelloux, Herve
    • Parasites, Hosts and Diseases
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    • 제56권1호
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    • pp.71-74
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    • 2018
  • Soluble antigens from an axenic culture of Entamoeba histolytica were used to develop a commercial ELISA kit to quantify anti-E. histolytica antibodies in sera of patients with extraintestinal amebiasis in non-endemic settings. The diagnostic specificity and sensitivity of the test were assessed retrospectively using 131 human serum samples with amoebic serologic status available. They were selected according to their results in immunofluorescence (IFAT) and were separated in 2 sample categories: 64 sera with positive results by IFAT and 67 with negative results by IFAT. The sensitivity and specificity of the ELISA kit were assessed at 95.0% and 94.0% compared to the IFAT. The test can be useful to exclude a potential diagnosis of amebiasis and could be used as a screening method since ELISA is an automated technique.

간질의 평가와 진단 - 발작간 뇌파소견을 중심으로 - (Interictal EEG in Diagnosis and Assessment of Epilepsy)

  • 박건우
    • 생물정신의학
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    • 제8권2호
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    • pp.233-238
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    • 2001
  • The routine interictal electroencephalogram(EEG) continues to play an important role in the diagnosis and treatment of epilepsy. The clinical investigation of brain disease in the last decade has been marked by dramatic advances in functional imaging, magnetic resonance scanning and digitized EEG. Epilepsy is a disorder of electrical hyperirritability of cerebral cortex and the interictal EEG remains the most convenient means available to demonstrate cortical hyperirritability. The sensitivity and specificity of the EEG in the diagnosis of epilepsy have been disputed. In this review, the type of EEG findings in epilepsy are reviewed and the sensitivity and specificity of interictal epileptiform discharge are discussed. And also the role of EEG in various clinical situations are summarized.

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아다부스트 학습과 비정방형 Differential LBP를 이용한 얼굴영상 특징분석 (Face Image Analysis using Adaboost Learning and Non-Square Differential LBP)

  • 임길택;원철호
    • 한국멀티미디어학회논문지
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    • 제19권6호
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    • pp.1014-1023
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    • 2016
  • In this study, we presented a method for non-square Differential LBP operation that can well describe the micro pattern in the horizontal and vertical component. We proposed a way to represent a LBP operation with various direction components as well as the diagonal component. In order to verify the validity of the proposed operation, Differential LBP was investigated with respect to accuracy, sensitivity, and specificity for the classification of facial expression. In accuracy comparison proposed LBP operation obtains better results than Square LBP and LBP-CS operations. Also, Proposed Differential LBP gets better results than previous two methods in the sensitivity and specificity indicators 'Neutral', 'Happiness', 'Surprise', and 'Anger' and excellence Differential LBP was confirmed.

EEC 4-Plate Test의 식육중 항균물질 검출감도와 항균물질 계열별 검출능 비교 조사 (Evaluatioon of EEc 4-Plate Test for the Sensitivity and Identification of Families of Antimicrobial Drugs in Mea)

  • 조병훈;진남섭;손성완;강환구;이혜숙;김재학;김봉환
    • 한국식품위생안전성학회지
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    • 제11권4호
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    • pp.307-314
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    • 1996
  • The European Economic Community four plate test(EEC 4-plate test, FPT, EU) has been used for monitoring antimicrobial drug residues in meat by Local Veterinary Service Center in Korea. This study was performed to evaluate sensitivity and group specificity of some antimicrobial drugs in FPT and to compare FPT with Charm II test. The minimal detectable levels of targeted antimicrobial drugs tested with standard solutions were 0.025∼1.0 ppm for 7 beta-lactams, 0.5∼1.0 ppm for 4 aminoglycosides, 0.05∼0.5 ppm for 5 macrolides, 0.05∼0.25 ppm for 3 tetracyclines and 0.25&1.0 ppm for 6 sulfonamides. In comparison of FPT and Charm II test, the results of FPT were not accord with those of Charm II test having the group specificity of seven families of antimicrobial drugs in meat samples except some families like tetracyclines.

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원발성 폐암에서 술전 종격동 검사의 의의 (The Value of Mediastinoscopy in Preoperative Staging of Primary Lung Cancer)

  • 서강석;전상훈;장봉현
    • Journal of Chest Surgery
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    • 제28권1호
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    • pp.37-41
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    • 1995
  • To determine the role of mediastinoscopy in the preoperative staging of the primary lung cancer, we studied 23 patients from January 1993 to December 1993 and compared the results of mediastinoscopy and computed tomographic scanning with the findings at thoracotomy. Mediastinoscopy was performed in 14 patients when they had larger than 10mm mediastinal nodes at computed tomographic scanning. Six of them were found to have metastatic nodes. Nine patients, who had negative computed tomographic scanning and negative mediastinoscopic results,underwent thoracotomy. One of them was found to have a metastatic mediastinal lymph node. When results from both series of patients were compared, the sensitivity and specificity of computed tomographic scanning showed 83.3% and 47.1% respectively with an accuracy of 56.5%. The results of mediastinoscopy showed that the sensitivity was 85.7%, the specificity was 100% and the accuracy was 95.7%.Because of the low accuracy rate of computed tomographic scanning, a more routine use of mediastinoscopy seems to be justified.

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Evaluation of Rapid Immunochromatographic Assay Kit for HBsAg-Screening Using Whole Blood

  • Shin, Hyeong-Soon;Heo, Tae-Ryeon
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제5권5호
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    • pp.362-365
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    • 2000
  • A rapid immunochromatographic assay kit using whole blood to screen hepatitis B surface antigen was developed and evaluated by using sera from 240 patients. The reference diagnosis was based on the results obtained with GENEDIA Anti-HBs Rapid kit which is very similar to the above kit except for the use of serum. The test demonstrated a good correlation with the reference immunochromatographic assay kit, that is, the sensitivity and the specificity of the kit was 100%, respectively. The rapid test kit using whole blood should be more convenient and useful for the diagnosis of hepatitis B virus because the kit does not need machines and time to prepare serum. In addition, this kit is safe from inadvertent infection during sample treatment because the blood is sterilized with hydrogen peroxide, eliminates the procedure required to prepare serum and reduces the possibility of exposure to infectious agents.

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Yolo-pose를 이용한 장단기 메모리의 낙상감지 시스템 연구 (Study of Fall Detection System of Long Short-term Memory Using Yolo-pose)

  • 정승수;김남호;유윤섭
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2022년도 추계학술대회
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    • pp.123-125
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    • 2022
  • 본 논문에서는 Yolo-pose를 이용하여 장단기 메모리(Long short-term Memory)에 적용하는 시스템을 소개한다. 영상데이터로부터 Yolo-pose를 이용하여 일상생활과 낙상으로 구분된 데이터를 추출하여 LSTM에 적용하여 학습시킨다. 학습은 오버피팅을 방지하기 위하여 8대2의 Validation을 진행하며 Confusion matrix로 나타낸다. Yolo-pose의 결과값은 sensitivity와 specificity 모두 100%를 기록하여 일상생활과 낙상을 잘 구분하는 것을 확인 하였다.

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A NEW SYSTEM OF VISUAL PRESENTATION OF ANALYSIS OF TEST PERFORMANCE: THE 'DOUBLE-RING' DIAGRAM

  • Stefadouros Miltiadis A.
    • 대한예방의학회:학술대회논문집
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    • 대한예방의학회 1994년도 교수 연수회(역학)
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    • pp.142-149
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    • 1994
  • Substitution of graphic representation for extensive lists of numerical statistical data is highly desirable by both editors and readers of medical journals, faced with an exploding abundance of contemporary medical literature. A novel graphic tool. the 'double-ring diagram', is described herein which permits visual representation of information regarding certain statistical variables used to describe the performance of a test or physical sign in the diagnosis of a disease. The diagram is relatively easy to construct on the basis of a number of primary data such as the prevalence and the true positive, true negative. false positive and false negative test results. These values are reflected in the diagram along with the values of other statistical variables derived from them. such as the sensitivity. specificity, predictive values for positive and negative test result. and accuracy. This diagram may be useful in visualizing a test's performance and facilitating visual comparison of performance of two or more tests.

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효소면역학적 방법에 의한 식물홀몬 분석 (Enzyme-linked Immunosorbent Assay of Plant Hormones)

  • 노기안
    • 한국작물학회지
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    • 제34권s01호
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    • pp.40-47
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    • 1989
  • In spite of the development of highly sophisticated instrument, the precise quantitation of plant hormones still has many difficulties. Due to their high specificity, sensitivity and minimal sample purification steps, immunological assays have been widely applied for plant hormone assay. Enzme-linked immunosorbent assay technique for the determination of plant hormones was developed by Voller in 1978. Immunological assays are accomplished by competition of labeled tracer antigen and unlabeled antigen for a limited number of specific antibodies. The use of enzyme as replacement labels for radioisotopes enabled much of the sensitivity and specificity of radioimmunoassay (RIA) to be retained but without the inherent disadvantage of high capital cost, potential health hazard, and short shelf life of the labeled reactants.

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