• 제목/요약/키워드: sensitivity and specificity

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산모에서 산후 유방통과 이혈 압통점과의 관계 연구 (A Study on the Correlation between Auricular Tenderness Testing on Mammary Gland Zone and Postpartum Breast Pain)

  • 성원영;김락형
    • Journal of Acupuncture Research
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    • 제26권5호
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    • pp.11-17
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    • 2009
  • Objectives : The objectives of this study were to examine the specificity and the sensitivity of tenderness testing on the ear about the postpartum breast pain, and to improve the efficacy of the tenderness test. Methods : Thirty women who visited in the hospital for recuperating 2-14 days after childbirth participated in this study. They answered the questionnaire of the severity of breast pain and their auricular acupuncture points were tested by a long metal probe with round tip 1.1mm in diameter. We analyzed the relationship between auricular tenderness testing on mammary gland zone[CW6] and postpartum breast pain with validity and significance as grouping 8 diagnosis methods. Results : When we consider above 'moderate pain' or 'severe pain' in the auricular tenderness testing as a positive sign, and above 'evere pain' or 'very severe pain' in the self-reported breast pain score as a positive symptom, the diagnostic efficacy was highest. The sensitivity for tenderness testing was 0.62-0.75, and the specificity was 0.64-0.72, and the sensitivity and the specificity in the contralateral ear were a little higher than in the ipsilateral ear. Conclusions : These results suggest that auricular tenderness testing can be objectified clinically and be used in diagnosis.

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Detection of Plasmodium vivax by Nested PCR and Real-Time PCR

  • Genc, Ahmet;Eroglu, Fadime;Koltas, Ismail Soner
    • Parasites, Hosts and Diseases
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    • 제48권2호
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    • pp.99-103
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    • 2010
  • Malaria is endemic in the Cukurova region while it is sporadic in other regions of Turkey. Therefore, the laboratory and clinical diagnosis of malaria is important for the treatment of malaria. In this study, 92 blood samples that were taken from the suspected malaria patients for routine diagnosis in a period of 10 years between 1999 and 2009 were analyzed. All of these blood samples were examined by microscopic examinations using Giemsa-stained thick blood films, nested PCR, and real-time PCR. The sensitivity-specificity and positive-negative predictive values for these diagnostic tests were then calculated. It was found that the positive predictive values of microscopic examination of thick blood films, nested PCR, and real-time PCR were 47.8%, 56.5%, and 60.9% for malaria, respectively. The real-time PCR was found to have a specificity of 75% and sensitivity of 100%, while specificity and sensitivity of nested PCR was found 81.2% and 97.7% according to the microscopic examination of thick blood films, respectively.

3축 가속도 센서 낙상 감지 시스템을 위한 낙상 특징 파라미터 추출 (Extraction of Fall-Feature Parameters for Fall Detection System Using 3-Axial Acceleration Sensor Data)

  • 임동하;박철호;유윤섭
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2013년도 추계학술대회
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    • pp.393-395
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    • 2013
  • 현대 사회에는 의학기술의 발전과 생활수준 향상 등으로 고령자들이 증가하고 있다. 고령자들의 낙상은 심한 경우 사망에 까지 이를 수 있는 상당히 큰 위협이 된다. 이러한 문제점을 해결하기 위해 낙상을 감지하는 여러 가지 알고리즘과 하드웨어 시스템의 필요성이 증가 하고 있으며 국내외에서 낙상 감지 시스템의 연구 결과가 발표 되고 있다. 본 논문에서는 3축 가속도 센서를 이용한 낙상 감지 시스템을 소개한다. 낙상 감지 시스템은 3축 가속도 센서 데이터로부터 몇 가지의 파라미터를 계산하여 낙상을 판별한다. 제안된 시스템을 이용하여 최대 98.3%의 sensitivity와 94.7%의 specificity 결과 값을 얻었다.

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발달문제 위험 아동 선별을 위한 한국형 Denver II 검사의 타당성에 관한 연구 (Validity of Korean Version of Denver II in Screening Children with Developmental Risk)

  • 신희선;권범선;임성오
    • Child Health Nursing Research
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    • 제11권3호
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    • pp.316-321
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    • 2005
  • Purpose: This study was done to evaluate the validity of Korean Denver ll developmental screening test in screening children with developmental risk. Method: The participants in the study were 113 children referred for developmental assessment in the department of rehabilitation of D University hospital. They were examined with the BSID (Bayley Scales of Infant Development) II and Korean Denver II by one occupational therapist. The data was analyzed by $x^2$ test and discriminant analysis. Results: There was a significant relationship between the Mental Developmental Index (MDI) of the BSID II and the result of the Korean Denver II. The sensitivity and specificity of Korean Denver II were 0.87 and 0.62 when abnormal MDI was defined as lower than 85 was used as a diagnosis of developmental delay. There was a significant relationship between the Psychomotor Developmental Index (PDI) of the BSID ll and the result 0.7 Korean Denver ll. The sensitivity and specificity of Korean Denver II were 0.83 and 0.51 The over-all hit ratio was $79.6\%$. Conclusion: The result showed that the Korean Denver II was valid and has good sensitivity and moderate specificity in screening developmental delay.

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Validation of the Korean Version of the Standardized Swallowing Assessment and the National Institute of Health Stroke Scale Among Acute Stroke Patients

  • Yun, Sukkyung;Kim, Hyemin;Mo, Eunji;Kim, Mingyeong;Kim, Minji;Gil, Chorong;Chang, HeeKyung
    • International Journal of Advanced Culture Technology
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    • 제6권4호
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    • pp.124-130
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    • 2018
  • Proper management and prevention of dysphagia are urgently needed in acute care of stroke patients in Korea. However, no highly sensitive and accessible nurse-led screening tools have been validated within the Korean settings. The purpose of this study was to validate a screening tool led by nurses to identify dysphagia and aspiration risks among acute stroke patients. Registered nurses (RNs) screened 131 residents from a university hospital in South Korea using the Korean version of the Standardized Swallowing Assessment (K-SSA). Results were validated against those from the Gugging Swallowing Screen (GUSS). Compared to results from the GUSS, with 9- and 14-point cutoffs, the K-SSA had a sensitivity of 0.80 and specificity of 0.90 [95% CI 0.806, 0.992] for screening dysphagia and 1.00 sensitivity and 0.94 specificity [95% CI 0.862, 1.000] for screening aspiration risks. The K-SSA demonstrated excellent sensitivity and specificity for screening individuals at risk of dysphagia and aspiration when led by RNs for acute stroke patients.

Use of Likelihood Ratios in Evidence-based Clinical Decision Making

  • Kim, Eu-Tteum;Pak, Son-Il
    • 한국임상수의학회지
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    • 제25권3호
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    • pp.146-151
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    • 2008
  • During the clinical decision making practitioners are often faced with performing diagnostic tests to solve the presenting problems seen in the patients. The diagnostic utility of a test has traditionally been described by technical terms such as sensitivity, specificity, and positive (PPV) and negative predictive value (NPV). Although well known, clinicians are frequently unclear about the concept and application of these terms in everyday evidence-based clinical decision making. Sensitivity and specificity, which are intrinsic properties of diagnostic tests, summarizes the characteristics of the test over a population. The PPV and NPV are greatly dependent on the population prevalence of disease, and thus they do not transferable to different patients or clinical settings. Besides, considering the fact that clinicians more often interested in knowing the extent to which a test result could confirm or exclude of a condition under consideration (posttest probability), these measures do not provide answers on this question. The likelihood ratios (LR) using the information contained in sensitivity and specificity are becoming increasingly popular for reporting the usefulness of diagnostic tests because this term provide an indication of posttest probability as a function of the pretest probability. In this article, clinical applications of LR are illustrated with some practical examples. Discussion is also included of the inherent limitations regarding diagnostic test characteristics.

Risk Factors of the 2-Year Mortality after Bipolar Hemiarthroplasty for Displaced Femoral Neck Fracture

  • Jung Wook Huh;Han Eol Seo;Dong Ha Lee;Jae Heung Yoo
    • Hip & pelvis
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    • 제35권3호
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    • pp.164-174
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    • 2023
  • Purpose: This study investigates the relationship between preoperative neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), albumin, and 2-year mortality in elderly patients having hemiarthroplasty for displaced femoral neck fracture (FNF). Materials and Methods: We retrospectively reviewed 284 elderly patients who underwent hemiarthroplasty for Garden type IV FNF from September 2014 to September 2020. Using the receiver operating characteristic curve, optimal cutoff values for LCR, NLR, and albumin were established, and patients were categorized as low or high. Associations with 2-year mortality were evaluated through univariate and multivariate Cox regression analyses. Results: Of the 284 patients, 124 patients (45.9%) died within 2 years post-surgery. The optimal cutoff values were: LCR at 7.758 (specificity 58.5%, sensitivity 25.0%), NLR at 3.854 (specificity 39.2%, sensitivity 40.0%), and albumin at 3.750 (specificity 65.9%, sensitivity 21.9%). Patients with low LCR (<7.758), high NLR (≥3.854), and low albumin (<3.750) had a statistically significant reduced survival time compared to their counterparts. Conclusion: Lower preoperative LCR and albumin levels, along with higher NLR, effectively predict 2-year mortality and 30-day post-surgery complications in elderly patients with Garden type IV FNF undergoing hemiarthroplasty.

후향적 자료분석을 통한 낙상위험 사정도구의 타당도 비교: 종합병원 입원 환자를 중심으로 (Validation of Fall Risk Assessment Scales among Hospitalized Patients in South Korea using Retrospective Data Analysis)

  • 강영옥;송라윤
    • 성인간호학회지
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    • 제27권1호
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    • pp.29-38
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    • 2015
  • Purpose: The purpose of the study was to validate fall risk assessment scales among hospitalized adult patients in South Korea using the electronic medical records by comparing sensitivity, specificity, positive predictive values, and negative predictive values of Morse Fall Scale (MFS), Bobath Memorial Hospital Fall Risk Assessment Scale (BMFRAS), and Johns Hopkins Hospital Fall Risk Assessment tool (JHFRAT). Methods: A total of 120 patients who experienced fall episodes during their hospitalization from June 2010 to December 2013 was categorized into the fall group. Another 120 patients, who didn't experience fall episodes with age, sex, clinical departments, and the type of wards matched with the fall group, were categorized to the comparison group. Data were analyzed for the comparisons of sensitivity, specificity, positive and negative predictive values, and the area under the curve of the three tools. Results: MFS at a cut-off score of 48 had .806 for ROC curves, 76.7% for sensitivity, 77.5% for specificity, 77.3% for positive predictive value, and 76.9% for negative predictive value, which were the highest values among the three fall assessment scales. Conclusion: The MFS with the highest score and the highest discrimination was evaluated to be suitable and reasonable for predicting falls of inpatients in med-surg units of university hospitals.

Reliability of Stool Antigen Tests: Investigation of the Diagnostic Value of a New Immunochromatographic Helicobacter pylori Approach in Dyspeptic Patients

  • Korkmaz, Huseyin;Findik, Duygu;Ugurluoglu, Ceyha;Terzi, Yuksel
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권2호
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    • pp.657-660
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    • 2015
  • Background: A diagnosis of H. pylori infection can be made by invasive or non-invasive methods. Several noninvasive diagnostic tests based on the detection of H. pylori stool antigen (HpSA) have been developed. The Genx H. pylori stool antigen card test is a new rapid, non-invasive test that is based on monoclonal immunochromatographic assay. The aim of this study was to determine its sensitivity, specificity, and diagnostic accuracy for diagnosing H. pylori infection in adult patients. Materials and Methods: A total of 162 patients were included in the study. A gastric biopsy was collected for histopathology and rapid urease testing. Stool specimens for HpSA testing were also collected. Patients were considered H. pylori positive if two invasive tests (histological and rapid urease tests) were positive. Results: Using the reference test, 50.6% of the samples were positive for H. pylori infection. The Genx H. pylori antigen test was positive in 19.7% of patients. The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of the Genx H. pylori antigen test were 51.6%, 96.0%, 88.8%, 76.1%, and 79.0%, respectively. Conclusions: The Genx H. pylori stool antigen card test is a new non-invasive method that is fast and simple to perform but provides less reliable results.

적외선 체온의 진단 정확도 평가 연구: 체계적 문헌고찰 (Reliability and Accuracy of Infrared Temperature: A Systematic Review)

  • 박성희
    • 성인간호학회지
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    • 제26권6호
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    • pp.668-680
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    • 2014
  • Purpose: The aim of this study was to investigate the accuracy of infrared temperature measurements compared to axillary temperature in order to detect fever in patients. Methods: Studies published between 1946 and 2012 from periodicals indexed in Ovid Medline, Embase, CINAHL, Cochrane, KoreaMed, NDSL, KERIS and other databases were selected using the following key words: "infrared thermometer". QUADAS-II was utilized to assess the internal validity of the diagnostic studies. Selected studies were analyzed through a meta-analysis using MetaDisc 1.4. Results: Twenty-one diagnostic studies with high methodological quality were included representing 3,623 subjects in total. Results of the meta-analysis showed that the pooled sensitivity, specificity, and area under the curve (AUC) of infrared tympanic thermometers were 0.73 (95% CI 0.70~0.75), 0.92 (95% CI 0.91~0.92), and 0.90, respectively. For axillary temperature readings, the pooled sensitivity was 0.67 (95% CI 0.62~0.73), the pooled specificity was 0.87 (95% CI 0.85~0.90), and the AUC was 0.80. Conclusion: Infrared tympanic temperature can predict axillary temperature in normothermic and in febrile patients with an acceptable level of diagnostic accuracy. However, further research is necessary to substantiate this finding in patients with hyperthermia.