• Title/Summary/Keyword: senkyunolide

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A Study on the Standardization of Ligustici Rhizoma and Angelicae Tenuissimae Radix including the Comparison for the Biological Activity on the Active Ingredients (Ligustici Rhizoma(고본(藁本))와 Angelica tenuissimae Radix(한국고본(韓國藁本)뿌리)의 규격화(規格化) 및 유효성분(有效成分)의 진통효과(鎭痛效果) 비교(比較)에 관한 연구(硏究))

  • Kim, Kwan-Ho;Lee, Sang-In;Kim, Ho-Cherl;Park, Ho-Koon;Rhee, Jae-Seong
    • The Journal of Korean Medicine
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    • v.18 no.1
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    • pp.187-197
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    • 1997
  • Major separation for the active ingredients and characterization of chemical properties in conjunction with screening test on animal were performed in order to analyze and standardize Ligustici Rhizoma or Angelicae Tenuissimae Radix as an important oriental herbal medicine for antiphlogistic or an important oriental herbal medicine for antiphlogistic or an anodyne. Furthermore the structure, composition and contents of ingredients for essential oil in Angelicae Tenuissimae Radix(Suckpo, Korea) were determined by means of Ge/MS followed by screening test on Z-ligustilide(82%) known as major ingredient as well as butylidenephthalide collected by HPLC with normal phase semiprep-column. The total active ingredient in Ligustici Rhizoma from China or Angelicae Tenuissimae harvested at Choonyang(Kyungnam, Korea), Jungsun(Kangwon, Korea), Suckpo(Kyungnam Korea), Youngchun(Kyungnam, Korea) have been determined showing higher abundant for three times on the product in Korea compared to that in China. In addition, the major component in Ahgelicae Tebyussunae Radux extract was found to be Z-ligustilide(70-80%) which is very different from that in Ligustici Rhizoma senkyunolide(39%) as major species. For screening test of Ligustici Rhizoma or Angelicae Tenuissimae Radix extracts toward the target animal, the efficiency has been shown the similarity on both extracts. Taking into account the level of ingredient, the total efficiency may be three times higher on Angelicae Tenuissimae Radix in Korea compared to Ligustici Rhizoma in China. As a result of present study, it is preferable to distinguish between Ligustici Rhizoma and Angelicae Tenuissimae Radix for better usage of oriental herbal medicine because of very different composition and abundant in spite of their similar screening effect.

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Effects of Forest Environments on Growth and Active Compound Contents of Ligusticum chuanxiong Hort. among Different Forest Sites (기후대별 산림환경에 따른 토천궁의 생육 및 유효성분 특성)

  • Kim, Nam Su;Jeon, Kwon Seok;Lee, Hyunseok
    • Korean Journal of Plant Resources
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    • v.33 no.5
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    • pp.419-427
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    • 2020
  • Ligusticum chuanxiong Hort. is included in Umbelliferae family, it is one of the Korean traditional medicinal plants as the roots have been used to treat diseases. In this study, the growth characteristics and active compound contents of L. chuanxiong were compared among the different forest sites. As a result, root diameter and root length of L. chuanxiong was the highest in Jeongseon. Also, the fresh weight and dry weight of L. chuanxiong were the highest in Jeongseon. The total content of active compound was 23.27 mg/g the highest in Bonghwa, and 21.59 mg/g in Jeongseon, 15.87 mg/g in Hamyang was accumulated. In this study compares three forest site for cultivating of L. chuanxiong in different climate zone that the best site to product yield were Jeongseon. In this sites were located in higher altitue and lower temperature than other sites, also there were shown that lower soil moisture contents and well-drained soil. It was shown yield and active compound contents of L. chuanxiong was influenced by micro-environment conditions like as altitude, temperature, soil conditions.