• CELLMED
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• v.11 no.1
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• pp.2.1-2.8
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• 2021

The clinical condition Amnesia causes difficulty in learning new information and the inability to recall past events. It is primarily concerned with recent memory loss. Majoon-e-Nisyan (MJN) is a polyherbal Unani formulation, present in a semi-solid form. It is widely used potent drug of the Unani System of Medicine (USM) for treating Nisyan (amnesia). In the present study polyherbal Unani formulation, MJN has been studied for its quality control and acute toxicity. Standardization (quality control) of drugs deals with drug identity, drug quality and purity determination. Standardization of MJN had been done as per the Unani pharmacopoeial parameters approved by World Health Organization (WHO) - Pharmacognostical parameters, Physico-chemical parameters, high-performance thin-layer chromatography (HPTLC), microbial load, aflatoxin, and heavy metals. Solvents and chemicals used in the study were of analytical grade and used instrument were calibrated. By conducting an acute oral toxicity study in rats, the safety of MJN was assessed. The limit test method of OECD guideline 425 was followed in the study. Results of standardization and standard operating procedures (SOPs) for preparation of MJN may serve as the standard reference in the future. The data generated in the study for the quality control of MJN proved the quality of formulation and shows that MJN is not toxic in rats following acute dosing up to 2000 mg/kg bw. The data obtained in the paper for MJN may be used as a standard guideline for preparation of the formulation which can save time, cost, and resources for future research endeavours.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.1
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• pp.24-37
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• 2022

Objectives : The purpose of this literature review is to analyze process of manufacture and formulation and toxicity of Geumgweyoryak(金匱要略)'s external applicants for modern and safe using. Methods : This study used the Geumgweyoryak(金匱要略) reprinted by Zhao Kaimei(趙開美) as basic data for a understanding of the manufacture and formulation and toxicity for external applicants. Among the 25 chapters, the 22 chapters were studied except for the last three chapters, which are known to be written by later writers. Based on the above, Geumgweyoryeok(金匱要略)'s external applicants was analyzed the process of manufacture, formulation and the toxicity. Results : There are 11 types of external applicants of Geumgweyoryak(金匱要略). Washing method(洗法) was used 2 times, Drop method(瀝法) was used 1 time, Smoke method(熏法) was used 2 times, Rubbing method(摩法) was used 1 time, Plaster method(敷法) was used 2 times, Invading method(浸法) was used 1 time, Suppository method (坐法) was used 2 times, Flatiron method(烙法) was used 1 time. According to classified the modern formulation, there are 4 types of powder formulation, 4 types of liquid formulation, 2 types of suppository, and 1 type of Semi-solid formulation. Especially toxic drugs, such as Realgar(雄黃) or Hydrocerussite(鉛粉), should be careful. When Realgar(雄黃) smokes, a toxic substance called AS2O3 can come out. Hydrocerussite(鉛粉) can cause lead poisoning. Lead increases the risk of anemia, dehydration, and lead neuropathy when chronically exposed. Conclusion : We supposed that this study can serve as a basic data to help clinical Korean doctors to use the prescription for external applicants more safely and to easily apply it in the form of external applicants.

• Journal of Plant Biotechnology
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• v.49 no.4
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• pp.331-338
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• 2022

Sunflower (Helianthus annuus L.) protoplasts were isolated from seven-day-old etiolated hypocotyls of 10 A line and four-week-old fully expanded young leaves of PI 441983 line in vitro seedlings using an enzymatic method. Purified protoplasts were collected by filtration and floatation in sucrose solution. Semi-solid protoplast culture was performed using the L4 regeneration protocol with various culture media and plating densities to achieve the highest efficiencies for protoplast culture of hypocotyl and mesophyll protoplasts of 10 A and PI 441983 lines, respectively. The concentrations in liquid L'4M medium and different plating densities were evaluated in two types of cytokinins, the adenine-type 6-benzyladenine (BA) and the phenylurea-type thidiazuron (TDZ). The highest colony formation was achieved in both sunflower lines when 0.5 mgL^-1 BA and 0.5 mgL^-1 TDZ were applied with a high plating density (3 × 10⁵ protoplasts mL^-1). These conditions led to 38.45% and 39.40% colony formation for hypocotyl protoplasts of the 10 A line and mesophyll protoplasts of the PI 441983 line, respectively. Moreover, many hypocotyl protoplast-derived colonies developed into micro-calli. In addition, superior development of both sunflower protoplasts was observed with all plating densities when BA was used in combination with TDZ. This finding will be applicable to future sunflower hybrid production via somatic hybridization.

• Steel and Composite Structures
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• v.50 no.3
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• pp.299-318
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• 2024

The main objective of this paper is to compute the far-field acoustic radiation (sound radiation) of functionally graded plates (FGM) loaded by sinusoidally varying point load subjected to the arbitrary boundary condition is carried out. The governing differential equations for thin functionally graded plates (FGM) are derived using classical plate theory (CPT) and Rayleigh integral using the elemental radiator approach. Four cases, segregated on power-law index k=0,1,5,10, are studied. A novel approach is illustrated to compute sound fields of vibrating FGM plates using the physical neutral surface with an elemental radiator approach. The material properties of the FGM plate for all cases are calculated considering the power law indexes. An in-house MATLAB code is written to compute the natural frequencies, normal surface velocities, and sound radiation fields are analytically calculated using semi-analytical formulation. Ansys is used to validate the computed sound power level. The parametric effects of the power law index, modulus ratios, different constituent of FGM plates, boundary conditions, damping loss factor on the sound power level, and radiation efficiency is illustrated. This work is the benchmark approach that clearly explains how to calculate acoustic fields using a solid layered FGM model in ANSYS ACT. It shows that it is possible to asymptotically stabilize the structure by controlling the intermittent layers' stiffness. It is found that sound fields radiated by the elemental radiators approach in MATLAB, ANSYS and literatures are in good agreement. The main novelty of this research is that the FGM plate is analyzed in the low-frequency range, where the stiffness-controlled region governs the whole analysis. It is concluded that a clamped mono-ceramic FGM plate radiates a lesser sound power level and higher radiation efficiency than a mono-metallic or metal-rich FGM plate due to higher stiffness. It is found that change in damping loss factor does not affect the same constituents of FGM plates but has significant effects on the different constituents of FGM plates.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.12
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• pp.696-704
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• 2015

This study was carried out to evaluate the optimum operational condition of Semi-continuously Fed and Mixed Reactor (SCFMR) to treat the dairy cow manure and saw dust mixture. Step-wise increase in organic loading rates (OLRs) or decrease in hydraulic retention times (HRTs) were utilized until the biogas volume became significantly decreased at mesophilic temperature ($35^{\circ}C$). The optimum operating condition of the SCFMR fed with TS 13% dairy cow manure and saw dust mixture was found to be an HRTs of 25 days and its corresponding OLRs of $4.45kg\;VS/m^3-day$. At this condition the biogas and methane production rates were 1.44 v/v-d and 1.12 v/v-d (volume of biogas per volume of reactor per day), respectively and the TVS removal efficiency of 37% was achieved. The successful operation with such a high OLR was due to the high reactor alkalinity concentration of 14,500~15,600 mg/L as $CaCO_3$ as a result of the characteristic of the original substrate, dairy cow manure and saw dust mixture whose alkalinity was more than 8,000 mg/L as $CaCO_3$. The parameters for the reactor stability, the ratios of volatile acids and alkalinity concentrations (V/A) and the ratio of propionic acid and acetic acid concentrations (P/A) appeared to be 0.11 and 0.43, respectively, that were greatly stable in operation. Free ammonia toxicity was not experienced due to the long term acclimation by the reactor TS content ranged 7.2~10.4% during the entire operational period.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.5
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• pp.491-503
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• 2014

In this paper, a $TM_{31}$ higher order mode half circular-ring microstrip antenna with monopole-like radiation characteristic for on-body communication is proposed. By using shorting vias, $TM_{31}$ resonance mode was excited, while achieving compact low-profile antenna with monopole-like radiation characteristics. To overcome the narrow bandwidth of a patch antenna, a C-shape half ring patch with shorting vias having $TM_{31}$ mode is closely located around a half circular patch. For size reduction, half mode is adopted. The proposed antenna has the overall dimensions of $0.25{\lambda}_0{\times}0.46{\lambda}_0{\times}0.025{\lambda}_0$ at the industrial, scientific, and medical(ISM) 2.45 GHz band(2.4~2.485 GHz) and the 10-dB return loss is 4.24 % ranging from 2.38 to 2.49 GHz. To verify body effect, two-thirds muscle equivalent semi solid phantom was fabricated and used to measure the antenna performance. A communication link is analysed to investigate the effect of human-body movements and antenna locations.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1613-1613
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• 2001

Fats and molasses are used, at the present time, in a considerable proportion as ingredients for the animal feed industry. They are mainly used as energy sources, but also they provide other characteristics of technological and nutritional interest (dust reduction, increase in palatability, etc). Both semi-liquid ingredients have numerous aspects in common from the point of view of their use in livestock feeds, as well as of their analytical control. Feed manufacturers use several criteria to evaluate the quality of fat and molasses. Furthermore, the traditional methods currently used, for their evaluation (eg. fatty acids, sugars, etc) are expensive and more sophisticated that the traditionally used for solid ingredients. The objective of the present work is to carry out a viability study to evaluate the ability of NIRS technology for the quality control of fat and molasses. Samples of liquid molasses (n = 42) and liquid fat ( n = 61), provided by a feed manufacturer, were scanned in a FOSS-NIR Systems 6500 monochromator equipped with a spinning module. The samples were analysed by folded transmission, using a sample cup of 0.1mm pathlength and gold surface reflector. For molasses, calibration equations were developed for the prediction of moisture (SECV=1.69%; $r^2$=0, 42), gross protein (SECV=0, 14%; $r^2$=0, 99), ashy (SECV=0, 60%; $r^2$=0, 84), NaCl (SECV=0, 05%; $r^2$=0, 99) and sugars (SECV=1, 04%; $r^2$=0, 86). For animal fats calibrations were obtained for the prediction of moisture (SECV=0, 14%, $r^2$=0, 88), acidity index (SECV=0, 83%, $r^2$=0, 82), MIU (SECV=0, 38%, $r^2$=0, 94) and unsaponifiables (SECV=0, 45%, $r^2$=0, 87). High accuracy calibration equations were also obtained for the prediction of the fatty acid profile. The equations have $r^2$values around 0.9 or highest. The results showed that NIRS technology could provide rapid and accurate results and reduce analytical costs associated to the quality control of two Important feed ingredients of a well known chemical variability.

• Journal of the Korean Society of Costume
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• v.6
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• pp.121-143
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• 1982

Many studies have done on Egyptian Clothing because its unique characteristic culture. However, I was facinated by the exhibitions of Tutankhamen burial treasures which were shown in San Francisco and New York in 1978 and 1979. I found out myself that there are several interesting aspects of clothing to compare 18th dynasty king, Tutankhamun and other dynasties in Egyptian culture. Therefore, I tryed to analized the Egyptian clothing including accessaries with theigr symbols durin 18th dynasty King, Tutankhamun. The most of people were shocked and amazed when they toured the exhibition of Tutankhamun articles which were the most incredible burial treasures in existence today. The body of the King has been embalmed, bandaged and fitted in eight layers of coffins with pure gold mask to represent the god Osiris. Among eight layers of coffins, one is pure solid gold in mummiform, two of mummiforms are made of compact wood covered with sheets of gold and inlaid with multi-colored glass-paste and semi-precious stones. The Egyptian belived that the soul continued to exist throughout eternity if it had passed on examination of its deeds on earth at a "Last Judgement" presided over by Osiris. They also believed that the mummified body could exist in the tomb as a habitation that the soul could revisited. Thus a proper burial was vital for a full existence in the hereafter. They buried dead person in the sealed vault of the tomb with some of the possessions he had used during his life time, such as his furniture, clothing and jewels. In this studies, I've tried to research to various clothings, and accessories with their symbols used during 18th dynasty king, Tutankhamun. The studies are shown as: I) Clothings of Tutankhamun dynasity of Kalasiris, Sheath skirt. Gala skirt, Loin skirt, Hike and Dalmatic. The Dalmatic was first seen in this dynasty. Probably the Roman Christian borrowed the Dalmatica from Egyptian Dalmatic. No where has the same design at the period. II) Egyptian of 18th dynasty Tutankhamun wore big headdress, broad collar necklace passium, pendants, armlets, rings and earrings with very beautiful, exquisite handcraft. They seem the first people who wore earrings in Egyptian history. III) The symbols of decorated items vulture, lotus...Upper Egypt Uraeus, papyrus...Lower Egypt scaravaeus, Nile Riber...rebirth man(Ankh), +...eternal life solar disc, gold...sun ostrich-feather...nobleness God, Horus' eye...protection against enemy IV) Also Egyptian prefered the straight line and a right angle which were the basic principles of architectural arrangement.

• Journal of Plant Biotechnology
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• v.34 no.1
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• pp.1-6
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• 2007

Effect of BA concentrations and culture methods on in vitro plant multiplication from shoot-tip cultures of Wasabia japonica was studied. Shoot-tips with leaf primordia and apical meristem were cultured on MS basal medium for all the experiments. Liquid medium for 2 weeks followed by semi-solid medium for 4 weeks containing 1.0 mg/L BA was the best to number of shoots (22.8) and shoot length (3.5 cm). Shoots proliferated could be divided into ca. 5 to 11 of cultures for the multiplication of plantlets. Divided plantlets showed root formation (90%) well onto MS basal medium without growth regulators like IBA and NAA. After rooting, all the plantlets transferred into the pots containing composed soil (bio-media Co., peatmoss $8{\sim}10%$, coir dust $66{\sim}70%$, zeolite $13{\sim}17%$, vermiculite $3{\sim}7%$, perlite $2{\sim}4%$) and grown well into whole plants with multiple shoots.

• Korean Journal of Plant Tissue Culture
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• v.28 no.3
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• pp.141-146
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• 2001

Protoplasts were isolated from cotyledons, hypocotyls, and mesophyll tissues of three species of Capsicum species (C. anuumm, C. bacatuum, and C. chacoense). Combination of Cellulysin (1%) and Macero-zyme (0.25%) in 0.65 M sorbitol was found to be the most effective for the digestion of cell wall, regardless of the Capsicum species. Antioxidant MES (2-［N-Morpholino］ethanesulfonic acid) in the enzyme solution helped protoplasts overcome browning. After 5 days of initial culture, Cell division occurred in modified K8p medium containing 1~5 mg/L zeatin, 0.5 mg/L IAA, 0.1~0.5 mg/L TDZ, and 1 mg/L 2,4-D under continuous dark condition at $25^{\circ}C$. Semi-solid agarose culture method was more effective than liquid culture, and it also protected the cells from browning caused by polyphenolic compound released during protoplast culture. A total of 4000 calli were obtained from protoplast culture of different capsicum species. All of these calli were transferred to the 100 combinations of regeneration media using various plant growth regulators; TDZ, IAA, 2ip, BAP, NAA, and zeatin. These calli derived from protoplast of three species of capsicum were, however, not differentiated into shoots.