• Archives of Craniofacial Surgery
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• v.23 no.2
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• pp.83-88
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• 2022

Nevus sebaceous of Jadassohn is a congenital cutaneous hamartoma with epidermal, sebaceous, follicular, and apocrine structures that usually appears at birth or in early childhood. It has the potential to generate a variety of secondary neoplasms of different lineages, and the risk increases with patient age. Although multiple neoplasms may occasionally arise within the same lesion, the coexistence of more than five secondary tumors is extremely rare. Here we report a case of seven secondary tumors including syringocystadenoma papilliferum, desmoplastic trichilemmoma, sebaceoma, trichoblastoma, pigmented trichoblastoma, sebaceous adenoma, and tumor of follicular infundibulum arising within a nevus sebaceous. The complete diagnosis relies on the histopathological analysis of multipoint biopsies and delicate pathological sections.

• Journal of the Korean Magnetic Resonance Society
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• v.10 no.1
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• pp.96-104
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• 2006

The gene coding for APG8a (At4g21980), a protein from Arabidopsis thaliana, is involved in the autophagy process. The protein is an interesting candidate for structure determination by NMR spectroscopy. Toward this end, APG8a has been produced recombinantly in Escherichia coli and typical NMR experiments such as $^{15}N-HSQC$, HNCA, HN(CO)CA, CBCA(CO)NH, HCCH-TOCSY, HNCO were performed. The backbone resonances, HN, N, CA, CB, and C' were sequence-specifically assigned, and the secondary structures including 3 $\alpha$ helices and $4\beta$ strands were deduced based on the assignments. Due to the intrinsic flexibility or the effect of the denaturant, the backbone resonances were not fully observed. Since the structure calculation by NMR data was not possible, the 3-dimensional model was built based on the sequence homology, and compared with the NMR results. The overall structure of the model could explain and complement the NMR derived secondary structures.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.237-240
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• 2002

In the present study, we perform LES of turbulent flow and temperature fields in a circular impinging jet at Re=5000 for two cases of H/D=2 and 6 (H denotes the distance between the jet exit and flat plate, and D does the diameter of the jet exit). In the case of H/D=2, the regular vortical structures observed in free jet do not exist because of the smaller distance than the potential core. The Nusselt number on the wall is largest at $r/D{\cong}10.67$ where vortex rings Impinge. At $r/D{\cong}1.5{\~}2.0$, the vortex rings induce the secondary vortices, resulting in a secondary peak in the Nusselt number there. In the case of H/D=6, the vortex rings change into three-dimensional vortical structures and the small-scale vortices impinge on the flat plate. The increase of turbulent intensity due to small-scale vortices results in the largest Nusselt number at the stagnation point.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.43-48
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• 2004

When structures are loaded by a combination of primary and secondary stresses, plasticity effects occur which cannot be evaluated by a simple linear addition of the effects resulting from the two independent stress systems. Thermal stress due to temperature gradient is classified as secondary stress. It is known that secondary stress is released as increase of plastic zone. In this paper, two and three dimensional elastic-plastic finite element analyses are performed for the cracked plates and pipes under combined thermal and mechanical loading. And V-factor is introduced to account for plasticity effect. The present results provide that V-factor is function of thermal factor and loading and is consistent regardless of geometry. We developed the prediction method of elastic-plastic fracture mechanics parameter under combined primary and secondary loading from the present results.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.11
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• pp.1540-1548
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• 2000

Near-wake flow field downstream of a circular cylinder in the wake-transition regime where fine-scale secondary vortices have a spanwise wavelength of around one diameter has been studied by means of phase-averaging from cinematic PIV data. A cross-correlation algorithm in conjunction with the FFT(Fast Fourier Transform)analysis and an offset correlation technique is used for obtaining the velocity vectors. Which the help of very high sampling rate compared to the shedding frequency, it is possible to obtain phase-averaged flow fields although the shedding is not forced but natural. Phase -locked three-dimensional vortical structures are reconstructed form the phase-averaged data in one x-y(cross-sectional) and several z-x(spanwise-streamwise)planes. In this process of phase-averaging in a z-x plane, a technique to freeze the secondary vortices relative to the centerline is applied. The formation process of the secondary vortices is shown by considering spatial relations between the primary Karman and the secondary vortices and their temporal evolutions.

• Journal of Mechanical Science and Technology
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• v.17 no.11
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• pp.1793-1800
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• 2003

The present study addresses an experimental investigation of the near field flow structures of supersonic, dual, coaxial, free, jet, which is discharged from the coaxial annular nozzle. The secondary stream is made from the annular nozzle of a design Mach number of 1.0 and the primary inner stream from a convergent-divergent nozzle. The objective of the present study is to investigate the interactions between the secondary stream and inner supersonic jets. The resulting flow fields are quantified by pitot impact and static pressure measurements and are visualized by using a shadowgraph optical method. The pressure ratios of the primary jet are varied to obtain over-expanded flows and moderately under-expanded flows at the exit of the coaxial nozzle. The pressure ratio of the secondary annular stream is varied between 1.0 and 4.0. The results show that the secondary annular stream significantly changes the Mach disc diameter and location, and the impact pressure distributions. The effects of the secondary annular stream on the primary supersonic jet flow are strongly dependent on whether the primary jet is under-expanded or over-expanded at the exit of the coaxial nozzle.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.10
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• pp.1355-1364
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• 2001

Characteristics of secondary vortices is topologically investigated in the near-wake region of a circular cylinder, where the Taylor's hypothesis does nut hold. The three-dimensional flow fields in the wake-transition regime were measured by a time-resolved PIV for various planes of view. The convection velocities of the Karman and secondary vortices are evaluated from the trajectory of the vortex center. Then, saddle points are determined by applying the critical point theory. It is shown that the inclination angle of the secondary vortices agrees well with the previous experimental data. The flow fields in a moving frame of reference have several critical points and the mushroom-like structure appears in the streamline patterns of the secondary vortices. Since the distributions of fluctuating Reynolds stresses defined by triple decomposition are closely related with the existence of secondary vortices, the physical meaning of them is explained in conjunction with the vortex center and saddle point trajectories.

• Journal of Positioning, Navigation, and Timing
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• v.10 no.4
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• pp.307-313
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• 2021

Modernized GNSS signal structures tend to use tiered codes, and all GNSSs use binary codes as secondary codes. However, recently, signals using polyphase codes such as Zadoff-Chu sequence have been proposed, and are expected to be utilized in GNSS. For example, there is Tiered Differential Polyphase Code (TDPC) using polyphase code as secondary code. In TDPC, the phase of secondary code changes every one period of the primary code and a time-variant error is added to the carrier tracking error, so carrier tracking ambiguity exists until the secondary code phase is found. Since the carrier tracking ambiguity cannot be solved using the general GNSS receiver architecture, a new receiver architecture is required. Therefore, in this paper, we describe the carrier tracking ambiguity and its cause in signal tracking, and propose a receiver structure that can solve it. In order to prove the proposed receiver structure, we provide three signal tracking results. The first is the differential decoding result (secondary code sync) using the general GNSS receiver structure and the proposed receiver structure. The second is the IQ diagram before and after multiplying the secondary code demodulation when carrier tracking ambiguity is solved using the proposed receiver structure. The third is the carrier tracking result of the legacy GPS (L1 C/A) signal and the signal using TDPC.

• Genomics & Informatics
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• v.21 no.1
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• pp.3.1-3.10
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• 2023

Characterization as well as prediction of the secondary and tertiary structure of hypothetical proteins from their amino acid sequences uploaded in databases by in silico approach are the critical issues in computational biology. Severe acute respiratory syndrome-associated coronavirus (SARS-CoV), which is responsible for pneumonia alike diseases, possesses a wide range of proteins of which many are still uncharacterized. The current study was conducted to reveal the physicochemical characteristics and structures of an uncharacterized protein Q6S8D9_SARS of SARS-CoV. Following the common flowchart of characterizing a hypothetical protein, several sophisticated computerized tools e.g., ExPASy Protparam, CD Search, SOPMA, PSIPRED, HHpred, etc. were employed to discover the functions and structures of Q6S8D9_SARS. After delineating the secondary and tertiary structures of the protein, some quality evaluating tools e.g., PROCHECK, ProSA-web etc. were performed to assess the structures and later the active site was identified also by CASTp v.3.0. The protein contains more negatively charged residues than positively charged residues and a high aliphatic index value which make the protein more stable. The 2D and 3D structures modeled by several bioinformatics tools ensured that the proteins had domain in it which indicated it was functional protein having the ability to trouble host antiviral inflammatory cytokine and interferon production pathways. Moreover, active site was found in the protein where ligand could bind. The study was aimed to unveil the features and structures of an uncharacterized protein of SARS-CoV which can be a therapeutic target for development of vaccines against the virus. Further research are needed to accomplish the task.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.37-40
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• 2001

We showed the result that an appreciable difference of secondary structures in the intracrystlline protein was observed between Normal and Deform shells. In order to understand the exact secondary structure of proteins, we investigated the changes in protein conformation from the specific layers via Fourier Self-Deconvolution(FSD) techniques, using ATR(Attenuated Total Reflection) information.