• Tuberculosis and Respiratory Diseases
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• v.76 no.6
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• pp.292-294
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• 2014

Primary tracheal amyloidosis (PTA) can lead to airway obstructions, and patients with severe PTA should undergo bronchoscopic interventions in order to maintain airway patency. Focal airway involvements with amyloidosis can only be treated with mechanical dilatation. However, the PTA with diffused airway involvements and concomitant cartilage destructions requires stent placement. Limited information regarding the usefulness of silicone stents in patients with PTA has been released. Therefore, we report a case of diffused PTA with tracheomalacia causing severe cartilage destruction, which is being successfully managed with bronchoscopic interventions and silicone stent placements.

• The Journal of Korean Medicine
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• v.38 no.3
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• pp.160-169
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• 2017

Objectives: Health in adolescent is very important in the whole life. But, students in Korea are very busy and hard to care about their health. This study is aimed to effectiveness and safety of effectiveness of School Doctor program in Korean Medicine. Method: From august to december, 2015, Korean medicine association in Sungnam city conducted school doctor program for 12 middle and 8 high school. School doctor visitied 8 times and treat, lecture and consulting for students and teachers. The number of students participating in health lecture is 1,905. The number of students participating in the school project was 147 students in junior high school and 187 students in high school, totaling 334 students. Results: The overall satisfaction rate of students was very high (83.2%) for school doctor program in Korean medicine. 92.8% of respondents answered that they should continue to school doctor program in Korean medicine. Conclusions: We find that Korean medicine is suitable for the school doctor program. But this study have some limitations. Large-scale prospective study will be needed.

• Korean Journal of Radiology
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• v.21 no.1
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• pp.117-117
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• 2020

• Molecules and Cells
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• v.45 no.12
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• pp.886-895
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• 2022

Malignant rhabdoid tumor (MRT) is a highly aggressive pediatric malignancy with no effective therapy. Therefore, it is necessary to identify a target for the development of novel molecule-targeting therapeutic agents. In this study, we report the importance of the runt-related transcription factor 1 (RUNX1) and RUNX1-Baculoviral IAP (inhibitor of apoptosis) Repeat-Containing 5 (BIRC5/survivin) axis in the proliferation of MRT cells, as it can be used as an ideal target for anti-tumor strategies. The mechanism of this reaction can be explained by the interaction of RUNX1 with the RUNX1-binding DNA sequence located in the survivin promoter and its positive regulation. Specific knockdown of RUNX1 led to decreased expression of survivin, which subsequently suppressed the proliferation of MRT cells in vitro and in vivo. We also found that our novel RUNX inhibitor, Chb-M, which switches off RUNX1 using alkylating agent-conjugated pyrrole-imidazole polyamides designed to specifically bind to consensus RUNX-binding sequences (5'-TGTGGT-3'), inhibited survivin expression in vivo. Taken together, we identified a novel interaction between RUNX1 and survivin in MRT. Therefore the negative regulation of RUNX1 activity may be a novel strategy for MRT treatment.

• Tuberculosis and Respiratory Diseases
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• v.61 no.5
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• pp.490-495
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• 2006

Leiomyoma of the bronchus is a very rare benign tumor of the lung. Most endobronchial leiomyomas occur as secondary foci of primary uterine leiomyoma. We herein report a case with endobronchial tumor that had a different pathology from a primary resected uterine leiomyoma and was therefor considered a primary endobronchial leiomyoma. A 51-year-old woman with a history of uterine myoma presented with productive cough and fever. Bronchoscopy revealed a lightly yellow colored mass lesion that totally obstructed the orifice of the left lower lobe of the lung. The diagnosis of leiomyoma was made by histological examination of the obtained specimen. We considered the possibility of a benign metastasizing pulmonary leiomyoma. For treatment and differential diagnosis, a left lower lobe lobectomy of the lung and total hysterectomy with bilateral salphingooopherectomy were performed. The differences between lung and uterine lesions were confirmed by morphologic finding and immunohistochemical staining. The pathological diagnosis was primary endobronchial leiomyoma combined with uterine myoma.

• The Journal of Korean Medicine
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• v.35 no.3
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• pp.32-39
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• 2014

Objectives: Elementary school national textbooks of 2013 were analyzed to examine the contents related to Korean medicine in the Korean elementary school curriculum. Methods: The contents related to Korean medicine were identified in the 118 elementary school national textbooks of 2013, and their proportion in the total textbooks was calculated. The Korean medicine-related contents were also analyzed. Results: There were twelve parts related to Korean medicine in seven chapters in six courses, and four directly related words and eight indirectly related words were found in twelve parts. The total number of lines for the contents related to Korean medicine were 205, which occupied 0.063% in the total elementary school national textbooks. The contents occupied 0.013% in the second grade, 0.265% in the third grade, 0.036% in the fourth grade, and 0.042% in the fifth grade. Conclusion: The results show that the coverage of Korean medicine in the elementary school national textbooks in 2013 does not provide enough information on Korean medicine. To help people get to know about Korean medicine and use it in the right way, it would be necessary to include more information about Korean medicine in textbooks, and continuous interest as well as research will be needed.

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.169.2-169.2
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• 2001

• Tuberculosis and Respiratory Diseases
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• v.55 no.3
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• pp.303-310
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• 2003

Background : Lymphangioma of the mediastinum is an uncommon benign tumor of lymphatic origin that is most often seen in children, is very rare in adults and is frequently discovered incidentally on chest x-ray exams. While radiology (CT and MRI) may suggest the diagnosis and allow an assessment of the operative difficulties, the histology of the surgical specimen is required for precise diagnosis. Complete resection is the only treatment; however, in some patients resection was incomplete because of the infiltrating character of these tumors, leading to recurrence. We report three cases of mediastinal lymphangioma with a review of the literature.

• Annals of dermatology
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• v.30 no.6
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• pp.733-735
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• 2018

• 대한방사선방어학회:학술대회논문집
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• 2009.11a
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• pp.128-129
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• 2009