• Title/Summary/Keyword: scale linkage

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Identification of Single Nucleotide Polymorphism Marker and Association Analysis of Marbling Score in Fas Gene of Hanwoo

  • Kim, Seung-Chang;Lee, Seung-Hwan;Lee, Ji-Woong;Kim, Tae-Hun;Choi, Bong-Hwan
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.1
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    • pp.23-28
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    • 2016
  • The Fas (APO-1, TNFRSF6) gene known as a member of the tumor necrosis factor receptor superfamily was selected for DNA marker development in Korean cattle. It is a cell membrane protein and mediates programmed cell death (apoptosis). We discovered single nucleotide polymorphisms (SNPs) within Fas gene in order to develop novel DNA markers related to economical traits at the genomic level. The sequences of whole exon and 1 kb range of both front and back of the gene were determined by direct-sequencing methods using 24 cattle. A total of 55 SNPs were discovered and we selected 31 common polymorphic sites considering their allele frequencies, haplotype-tagging status and linkage disequilibrium (LD) for genotyping in larger-scale subjects. The SNPs were confirmed genotype through the SNaPshot method (n = 274) and were examined for a possible genetic association between Fas polymorphisms and marbling score. So, the SNPs that were identified significant are g.30256G>C, g.31474C>A, g.31940A>G, and g.32982G>A. These results suggest that SNPs of Fas gene were associated with intramuscular fat content of meat quality traits in Korean cattle.

Identification of Polymorphisms of Fas Gene and Association Analysis in Hanwoo

  • Kim, Seung-Chang;Lee, Seung-Hwan;Kim, Bum-Soo;Kim, Tae-Hun;Seong, Hwan-Hoo;Oh, Sung-Jong;Yoon, Du-Hak;Choi, Bong-Hwan
    • Journal of Animal Science and Technology
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    • v.53 no.6
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    • pp.511-516
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    • 2011
  • Fas gene known to associate with intramuscular fat content in Korean cattle was selected for DNA marker development. Fas (APO-1, CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, is a cell membrane protein that mediates apoptosis (programmed cell death). We discovered single nucleotide polymorphisms (SNPs) within Fas gene in order to develop novel DNA markers at genomic level. Of this gene to search for SNP, sequences of whole exon and 1kb range of both front and back of the gene using 24 cattle were determined by direct-sequencing methods. As a result, 16 SNPs in exon, 37 SNPs in intron and 2 SNPs in promoter region, a total of 55 SNPs were discovered. In these SNPs, thirty-one common polymorphic sites were selected considering their allele frequencies, haplotype-tagging status and Linkage Disequilibrium (LD) for genotyping in larger-scale subjects. Selected SNPs were confirmed genotype through SNaPshot method (n=274) and were examined for possible genetic association of Fas polymorphisms with carcass weight (CWT), eye muscle area (EMA), and backfat thickness (BF). So, the SNP have been identified significant g.-12T>G, g.1112T>G and g.32548T>C. These results suggest that polymorphism of Fas gene was associated with meat quality traits in Hanwoo.

Linking of Items in Two Function-related Questionnaires to the International Classification of Functioning, Disability and Health: Shoulder Pain

  • Lee, Hae Jung;Song, Ju Min
    • The Journal of Korean Physical Therapy
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    • v.30 no.6
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    • pp.239-245
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    • 2018
  • Purpose: This study was to identify international classification of functioning, disability and health (ICF) categories that could be linked conceptually to disability of arm, shoulder and hand (DASH) items and short form of health survey 36 (SF-36) items for persons with shoulder pain. Methods: Linkage between each item in DASH and SF-36 and the categories in the ICF were assessed. The linking process was performed by ten health professionals following the linking rule. One hundred four patients with shoulder pain were enrolled from 12 private clinic outpatient departments and participated in this study. Pearson correlation coefficients were used to assess the relationships between each scale item and the linked ICF code. Results: Thirty DASH items were able to be linked to 30 ICF codes, whereas the 36 items in SF-36 were only linked to 17 ICF codes. General health items included in SF-36 could not be linked to a relevant ICF concept. There was a high correlation between the two measurement tools and the linked ICF codes, DASH and its ICF code list (r =0.91), SF-36-Physical Health and its code list (r =-0.62), and SF-36-Mental Health and its code list (r =-0.72). Conclusion: The results suggest that concepts within each item in DASH can be linked to ICF codes for patients with shoulder pain, however, the concepts in the SF-36 items had limited linkage to ICF codes. The shoulder-specific functional tool, DASH can be expressed with ICF codes and, therefore, its use can promote data standardization and improve communication between professionals.

Novel System Modeling and Design by using Eclectic Vehicle Charging Infrastructure based on Data-centric Analysis (전기차 충전인프라 및 데이터 연계 분석에 의한 시스템 모델링 및 실증 설계)

  • Kim, Hangsub;Park, Homin;Jeong, Taikyeong;Lee, Woongjae
    • Journal of Internet Computing and Services
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    • v.20 no.2
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    • pp.51-59
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    • 2019
  • In this paper, we analyzed the relationship between charging operation system and electricity charges connected with charging infrastructure among data of many demonstration projects focused on electric vehicles recently. At this point in time, due to the rapid increase in demand for the electric charging infrastructure that will take place in the future, we can prepare for an upcoming era in the sense of forecasting the demand value. At the same time, demonstrating and modeling optimized system modeling centering on sites is a prerequisite. The modeling based on the existing small - scale simulation and the design of the operating system are based on the data linkage analysis. In this paper, we implemented a new optimized system modeling and introduced it as a standard format to analyze time - dependent time - divisional data for each vehicle and user in each point and node. In order to verify the efficiency of the optimization based on the data linkage analysis for the actual implemented electric car charging infrastructure and operation system.

A Study on Implementation of a Disaster Crisis Alert System based on National Disaster Management System

  • Hyong-Seop, Shim
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.1
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    • pp.55-63
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    • 2023
  • In this paper, we propose a function and service of the Disaster Crisis Alert Management System that automatically analyzes the situation judgment criteria to issue a disaster crisis alert and a plan to operate in the National Disaster Management System(NDMS). In the event of a disaster, a crisis alert(interest-caution-alert-serious) is issued according to the crisis alert level. In order to automatically analyze and determine the crisis alert level, first, data collection, crisis alert level analysis, crisis alert level judgment, and disaster crisis alert management system that expresses the crisis alert level by spatial scale(province, city, district) were implemented. The crisis alert level was analyzed and expressed in two ways by applying the intelligent crisis alert level(determination of regional sensitivity, risk level, and crisis alert level) and the crisis alert standard of the crisis management manual(province-level standard setting). Second, standard metadata, linkage of situation information of target) and API standards for data provision are presented to jointly utilize data linkage and crisis alert data of the disaster and safety data sharing platform so that it can be operated within the NDMS.

A study on time series linkage in the Household Income and Expenditure Survey (가계동향조사 지출부문 시계열 연계 방안에 관한 연구)

  • Kim, Sihyeon;Seong, Byeongchan;Choi, Young-Geun;Yeo, In-kwon
    • The Korean Journal of Applied Statistics
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    • v.35 no.4
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    • pp.553-568
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    • 2022
  • The Household Income and Expenditure Survey is a representative survey of Statistics Korea, which aims to measure and analyze national income and consumption levels and their changes by understanding the current state of household balances. Recently, the disconnection problem in these time series caused by the large-scale reorganization of the survey methods in 2017 and 2019 has become an issue. In this study, we model the characteristics of the time series in the Household Income and Expenditure Survey up to 2016, and use the modeling to compute forecasts for linking the expenditures in 2017 and 2018. In order to evenly reflect the characteristics across all expenditure item series and to reduce the impact of a specific forecast model, we synthesize a total of 8 models such as regression models, time series models, and machine learning techniques. In particular, the noteworthy aspect of this study is that it improves the forecast by using the optimal combination technique that can exactly reflect the hierarchical structure of the Household Income and Expenditure Survey without loss of information as in the top-down or bottom-up methods. As a result of applying the proposed method to forecast expenditure series from 2017 to 2019, it contributed to the recovery of time series linkage and improved the forecast. In addition, it was confirmed that the hierarchical time series forecasts by the optimal combination method make linkage results closer to the actual survey series.

The Linkage of Foreign Direct Investment, Economic Growth, and Environmental Regulations : Scale Effect and Technique Effect (외국인직접투자, 경제성장, 환경규제의 관계분석 : 규모효과와 기술효과를 중심으로)

  • Kim, KwangUk;Kang, SangMok
    • Environmental and Resource Economics Review
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    • v.18 no.3
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    • pp.523-544
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    • 2009
  • The purpose of this paper is to estimate the impact of foreign direct investment on environmental performance for 27 OECD countries using endogenous environmental policy model. The empirical test shows that with 1% increase in the ratio of inflow stock of foreign direct investment over domestic capital stock, emission on NOx and $CO_2$ will increase by 0.0071%(NOx) and 0.0165%($CO_2$) and 1% increase in the ratio of foreign capital stock induces 0.044%(fixed effect) and 0.047%(random effect) of economic growth. 1% increase of per labor total output increases 2.038%(fixed effect) or 1.890%(random effect) in reinforcement of environmental regulation. However, we could not confirm the Porter's hypothesis that the more strong environmental regulation leads technical innovation. The scale effects (0.0119, 0.0172) are estimated higher than the technical effects (-0.0048, -0.0007) in two pollutants (NOx, $CO_2$). It implies that each country needs to increase pollution abatement and control expenditure more aggressively to protect environment.

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A Study Of EIS Build Method by ISP Base for Large Scale Enterprise Associate Company (대기업 협력 업체를 위한 ISP 기반의 EIS 구축 방법에 관한 연구)

  • Kim, Soo-Kyum;Ha, Soo-Cheol
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.1
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    • pp.159-166
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    • 2010
  • It is noteworthy that EIS Consulting Method by ISP based on ERP Linkage Type for Large Scale Enterprise Associate Company. In this thesis, IT Strategy plan and methodology are suggested in order to solve the several problems including standardization on implementation of EIS Introduction and operation between large-small enterprise. Integration of business and information technical is made by Business management group's continuous IT concern and future information strategy. Also this paper proposes ISP Planning method (environment analysis, present analysis, IT analysis, target IT plan etc..), EIS Construction (based ERP Real data/time). In addition to, we suggest to use electron industry model and LCD/LED field in this system.

The Evolution and Development Strategies of Event Tourism in the Case of Young-deung Festival at Chindo (이벤트관광의 성장과정과 활성화 방안 -전남 진도 영등제를 사례로-)

  • 추명희
    • Journal of the Economic Geographical Society of Korea
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    • v.1 no.2
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    • pp.103-134
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    • 1998
  • This paper examined the evolution and development strategies of Young-deung Festival holding in Chindo since 1978. The Young-deung Festival is a representative event tourism in Korea. The water between Hoidong and Modo in Chindo, a small islet 2.8km off the coast, part to reveal a path 40m wide as a result of the moon influence on the tides. This phenomenon is called “young-deung-sal”on the Chindo. This event began on a small scale highlighting the treasury of traditional folkfore and shamanism peculiar to these islands, various cultural resources, and local place attraction such as young-deung-sal. But, in the early 1990s, with the introduction of systematic management and a variety of programs, the small village festival has steadily evloved in the scale aspects of the program, budget, profit, and the number of visitors participating in festival. In addition, the period of festival was prolonged for three days and visitors from other provinces have steadily increased, in particular visitors from Seoul and Gyoungkee have steadily increased. In order to develop the Young-deung Festival, the followings should be done: creation of local image through place attraction, private organization in supporting festival, adoption of management techniques for the local economic activites, and extension of linkage with tourists places around Chindo, target visitor marketing through a continuous visitor survey.

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IPA Analysis of the Components of the Scale-up Entrepreneurial Ecosystem of Startups (스타트업의 스케일업 창업생태계 구성요소의 IPA 분석)

  • Hey-Mi, Yun;Jung-Min, Nam
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.6
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    • pp.25-37
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    • 2022
  • The purpose of this study is to survey startup founders within 7 years of founding the importance and satisfaction of the components of the scale-up entrepreneurial ecosystem at the national level in Korea and analyze the direction of scale-up policy by component using IPA (importance-performance analysis). Since the perception of founders, who are the subjects of the entrepreneurial ecosystem, affects the quantity and quality of start-ups, research is needed to analyze and diagnose the perception of scale-up components. For the development of the national economy and entrepreneurial ecosystem, companies that emerge from startups to scale-up and unicorns must be produced, and for this, elements for the scale-up entrepreneurial ecosystem are needed. The results of this study are as follows. First, the importance ranking of the components of the scale-up entrepreneurial ecosystem recognized by founders was in the order of "Financial support by growth stage," "Support for customized scale-up for enterprises," "Improvement of regulations," "Funds dedicated to scale-up," "large-scale investment," and "nurturing technical talents." Second, the factors that should be intensively improved in the importance-satisfaction matrix in the future were 'Pan-Government Integration Promotion Plan', 'Scale-Up Specialized Organization Operation', 'Company Customized Scale-Up Support', 'Regulatory Improvement', and 'Building a Korean Scale-Up Model'. As a result, various and large financial capital for the scale-up entrepreneurial ecosystem, diversification of scale-up programs by business sector, linkage of start-ups and scale-up support, deregulation of new technologies and new industries, strengthening corporate-tailored scale-up growth capabilities, and providing overseas networking opportunities can be derived. In addition, it is expected to contribute to policy practice and academic work with research that derives the components of the domestic scale-up entrepreneurial ecosystem and diagnoses its perception.