• Title/Summary/Keyword: safety score

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Effects of Lavender, Lemon and Eucalyptus Essential Oil on Th2 related Factors of DNCB-induced Atopy dermatitis in NC/Nga Mice Model (라벤더, 레몬, 유칼립투스 혼합 에센셜오일이 아토피 피부염 동물 모델의 Th2 관련인자에 미치는 영향)

  • Kim, Hyeon-Ah;Yun, Mi-Young;Song, Hyang-Hee;Cheong, Kwang-Jo;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
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    • v.13 no.1
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    • pp.53-61
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    • 2010
  • Purpose : To investigate the effects of the lavender, lemon and eucalyptus oil mixture on the atopy dermatitis skin lesions induced on NC/Nga Mice by dinitrochlorobenzene (DNCB). Material and Method : For this purpose, we fabricated the oil mixture blending three essential oils (lavender, lemon, eucalyptus : ELL) with one carrier oil (jojoba) and apply it on the atopic dermatitis skin lesions of NC/Nga Mice. Atopic dermatitis in NC/Nga Mice was induced by DNCB treatment on the dorsal skin of mice for 8 weeks. The mixture of ratio of each essential oil drop was 1 (eucalyptus) : 2 (lemon) : 2 (lavender) and this mixture was blended with jojoba oil 50ml (0.025%). The ELL-ointment was supplied for 8 weeks. We evaluated the effects of ELL on cell viability of mouse lung fibroblast, clinical skin features and severity, the level of serum Immunoglobulin (Ig) E & Ig G1, Interleukin (IL)-4, IL-13 and Interferon (IFN)-$\gamma$. Results : ELL showed safety on the cell viability of mouse lung fibroblast compared with control group. The cell viability was measured by SRB method. The effects of ELL on clinical skin features and severity in DNCB-induced dermatitis model of NC/Nga mice was significant compared with control group. EEL also showed significant effects on clinical symptom score compared with control group. Serum IgE & IgG1 level and development of atopy dermatitis skin lesions were evaluated. Serum IgE & IgG1 production was significantly down-regulated in EEL group compared with control group. ELL also down-regulated the levels of IL-4 and IL-13, and up-regulated the level of IFN-$\gamma$ compared with control group significantly. Conclusion : ELL was effective on atopy dermatitis by modulating Th2 related factors.

Development of Evaluation Factors for Selecting Operator of Rail Traffic-Control (철도 관제권 운영주체 선정을 위한 평가항목 개발)

  • Oh, Jae Kyoung;Chung, Sung Bong;Kim, Ji Yeon;Kim, Sigon
    • Journal of Korean Society of Transportation
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    • v.32 no.4
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    • pp.327-335
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    • 2014
  • The Korean government, as of last year, is attempting to introduce a competitive system in the rail-market. However there are some pertinent issues which need to be addressed in order to select the best possible organization for optimum railway traffic control. As there are no standard guidelines in selecting an agency, objective evaluation factors need to be properly applied to ensure the best possible decision is made. Through literature review and various interviews with experts, appropriate criteria were selected to evaluate the suitability of each potential operator. As generally mentioned, both safety and efficiency play vital roles in the selection process but in addition, there are other factors such as security and fairness, which also need to be considered. The individual weight of these factors were calculated by the AHP, in which three groups of experts were interviewed to acquire their expertise. According to the results, as a potential operator, the score of a railway operating company and the management cooperation of railway is 2.75 and 3.85, respectively. In the future, in preparation towards becoming a competitive rail-market, this research is expected to assist in choosing the best party to control the rail traffic system.

Development of Family Nursing Phenomena in Korea by Retrospective Method of ICNP (ICNP의 후향적 개발방법에 의한 한국가족현상)

  • Yun, Sun-Nyeong;Kim, Hyeon-Suk;Gwon, Yeong-Suk;Park, Gyeong-Min;Kim, Hwa-Jung;Lee, Ji-Hyeon;Go, Yeong-Ae;So, Ae-Yeong;Yang, Sun-Ok;Jeon, Gyeong-Ja;Lee, In-Suk;Kim, Yeom-Im;Kim, Eun-Hui
    • Research in Community and Public Health Nursing
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    • v.10 no.2
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    • pp.275-290
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    • 1999
  • The Objectives of this study were to identify family nursing phenomena at the community in Korea and to contribute to build up family domain of International Classification for Nursing Practice. The method of this study was used retrospective one among three methods to develop ICNP during the period from April 1997 to June 1999. The procedure was to choose nursing phenomena using preliminary terms(stepl) from the reports on family nursing care of the nursing students of 5 junior colleges of nursing and 5 colleges of nursing. The study group members identified 3 common family nursing phenomena with 5 characteristics related to each phenomenon. In order to consensus the appropriate characteristics of a phenomenon(step2), 17 study group members had regrouped nursing phenomena and scored its characteristics 5 times. The essential characteristics of each family phenomenon were selected above 3.5 mean score from related characteristics(step 3). Finally, 17 phenomena were named preferred terms such as following, that was selected after investigated preliminary terms(step4). Family nursing phenomena in Korea are named as Lack of family interaction in community. Social isolation. Lack of social support system in community. Disturbance in parent role, Disturbance in marital role, Dissatisfaction of sexual life, Disturbance in family communication, Inappropriate family coping, Lack of family intimacy, Inappropriate family power structure, Family violence. Unhealthy life style. Deficit of financial management skill and support. Inadequate care a sick member. Insecure safety and hygiene in neighborhood, Inadequate home-sanitation. Inadequate home-making. Family nursing phenomena in Korea were partially confirmed family architecture of ICNP, Beta version. by this study. Further study on Family nursing phenomena in Korea will be required to support evidence through literature review of nursing classifications or field studies.

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A Study on Health Promotion Needs Assessment of the Rural Elderly in Korea (한국농촌노인의 건강증진관리요구에 관한 연구)

  • Cho So Young;Kim Jum Ja
    • Journal of Korean Public Health Nursing
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    • v.10 no.2
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    • pp.146-161
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    • 1996
  • This study was purposed to find health promotion and care needs of the elderly in rural area of Korea. As the rural elderly are limited in accessibility to health care resources and could not immediately solve their health care needs when they need. health promotion and care services are expected to bring better and more practical solutions of their health care needs. Thus, the type of health care services to be developed in Korea rural area is discussed to have emphasis on health care service component in addition to health promoting components. Methods of this study was based on survey data analysis : total 322 persons aged older than 55 living at one 'Kun' in Korea administrative unit were interviewed by health workers working at the region and also get trained for this study data collection. The data collection interview was continued from February till May in 1996. The interview questions were modified with adjustment to Korea situation. with basis of the WHO's health promotion program components. The collected data were analyzed using SAS program for frequency, correlation, regressions. The major findings were as follows : (1) $74.8\%$ of the surveyed were sick at the survey time point. and $95.9\%$ known the diagnosis name of the disease. The most frequently complained diseases were Muscular-Skeletal diseases $(43.7\%)$. $34\%$ of those sick had never treated or discontinued therapeutic procedures. so that shown the necessity of systematic and usual health care services with health promotion program development for the elderly. (2) The percent of those who make social participation was $95.3\%$. and the activities were visiting neighbors $(70.4\%)$ and lack of qualified social activity programs. (3) $78.1\%$ of the surveyed had health counseling and education from professional health workers. Those ceased smoking and drinking were $59.6\%,\; 60.3\%$. respectively. Those had no application of therapeutic drugs or nutrion supplements was $40.7\%\;and\;94.1\%$ had regular meals. Those practiced exercises was low remarking $17.7\%$. (4) Positive health behaviors were better carried out by sick groups than by the healthier. except smoking. regular meals. and exercise. $17.5\%$ of sick group smoke more than one case of cigarettes. in contrast to $9.5\%$ of the healthier. (5) Mental health status was heathier among positive health behavior earners. Health counseling and education shown better score of mental health than those never counseled. (6) Positive health behavior practice frequency did not show significant differences when crossed by social activity participation status. (7) Health behaviors of the rural elderly people were carried out better when they had positive 'continuency in therapeutic procedure' 'health status'. 'familial relationship'. 'Health Status' of the rural olderly were explained by 'exercise'. 'drinking'. 'familial relationship'. 'activities of daily living'. Thus, health behaviors practice mutually interact with health status. In conclusion. the health promotion and care program component are recommended to include ation on the necessity of positive health promotion active social acitivities. pleasant life style, adaption into changes on the elderly, safety in residential area. community acitivity and resource utilization. etc .. in addition to the elderly's disability and sickness caring services.

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The Effect of Recombinant Human Growth Hormone on Growth in Children with Nephropathy Receiving Long-term Steroid Therapy (장기간의 스테로이드 치료를 받고 있는 신병증 환아에서 Recombinant Human Growth Hormone의 효과)

  • Kim, Se-Jin;Kim, Sun-Kyoung;Kim, Sung-Do;Cho, Byoung-Soo
    • Childhood Kidney Diseases
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    • v.10 no.2
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    • pp.142-151
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    • 2006
  • Purpose : Growth retardation is one of the serious problems in children with nephropathy requiring long-term steroid therapy. We observed the efficacy and safety of recombinant human growth hormone(rhGH) on the growth in children with long-term steroid therapy. Methods : We studied 60 children(male 47, female 13) with nephropathy who received rhGH(1 U/kg/week) for more than 0.5 years($1.39{\pm}1.12$). Their mean age was 11.0 years($11.17{\pm}2.62$). They received steroid therapy from January 1987 through July 2005, and the mean duration of steroid therapy was $4.32{\pm}2.97$ years. Among the patients, there were 32 nephrotic syndrome, 9 IgA nephropathy, 4 mesangial proliferative glomerulonephritis, 4 focal segmental glomerulosclerosis, 2 Henoch $Sch\ddot{o}nlein$ nephritis, 2 Alport syndrome and 7 other cases. Data were gathered on the growth parameters, such as growth velocity, height standard deviation score(SDS), IGF-1, IGFBP-3, bone mass density(BMD) and general chemistry changes. Results : Height velocity increased significantly with rhGH therapy from $3.29{\pm}1.95$ to $8.66{\pm}3.75$(cm/yr) and height SDS decreased from $-0.72{\pm}0.93$ to $-1.04{\pm}0.86$ at one year after steroid therapy but increased to $-0.55{\pm}0.96$ at one year after rhGH administration(P<0.05). BMD improved from $0.71{\pm}0.14$ to $0.79{\pm}0.15g/cm^2$(P<0.05). IGF-1 increased from $445.09{\pm}138.01$ to $506.62{\pm}181.31ng/mL$(P<0.05). IGFBP-3 decreased from $4073.75{\pm}700.78$ to $3933.61{\pm}789.25ug/L$ numerically, but there was no statistically significant difference(P=0.533). Conclusion : The administration of rhGH in the short stature patients who received long-term steroid therapy showed improvement in growth parameters such as SDS, growth velocity, and BMD without significant side-effects or changes in the biochemical parameters.

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Moxibustion for Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis (전립선 비대증에 대한 뜸치료의 효과 : 체계적 문헌고찰과 메타분석)

  • Bae, Go-eun;Lee, Seung-hwan;Hong, Jin-woo;Lee, In;Kim, So-yeon;Choi, Jun-young;Han, Chang-woo;Yun, Young-ju;Park, Seong-ha;Kwon, Jung-nam
    • The Journal of Internal Korean Medicine
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    • v.39 no.3
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    • pp.372-388
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    • 2018
  • Objective: This study evaluates the effectiveness and safety of moxibustion for benign prostatic hyperplasia (BPH). Methods: Using the keywords "benign prostatic hyperplasia", "benign prostatic hypertrophy", "benign prostatic enlargement", "prostatic hyperplasia", and "moxibustion", we searched papers in numerous databases, including National Discovery for Science Leaders (NDSL), Korean Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS), PubMed, Embase, and CENTRAL. The search range included randomized controlled trials (RCTs). Papers not matched with inclusion criteria were excluded. The methodological quality of each RCT was assessed using the Cochrane risk-of-bias tool. Where appropriate, meta-analyses were performed. Results: Initially, 77 studies were found. Of these, 11 duplicate studies were removed and 27 were excluded following title and abstract screening. After the remaining 39 papers were scanned, 13 RCTs were selected and analyzed. Among these 13 RCTs, five compared moxibustion therapy and oral medication, seven compared moxibustion plus acupuncture therapy and oral medication, and one compared moxibustion plus acupuncture therapy and sham-moxibustion. The meta-analysis showed positive results for the use of moxibustion therapy in terms of International Prostate Symptom Score (IPSS), Quality Of Life (QOL), Maximum Flow Rate (Qmax), Prostate Volume (PV), and the efficacy rate. The meta-analysis showed positive results for the use of moxibustion plus acupuncture therapy in terms of IPSS, QOL, and the efficacy rate. Conclusions: This meta-analysis of clinical trials suggests that moxibustion is effective intreating BPH patients. The results of this study could be applied to clinical treatment of BPH. However, additional large-scale clinical researches should be conducted.

A Study on the Development of Baby Powder Using Silk gland Powder of Silkworm (누에생실샘 미세분말을 이용한 베이비파우더 소재 개발에 대한 연구)

  • Chon, Jeong-Woo;Kweon, Haeyong;Jo, You-Young;Ryu, Kang-Sun;Lee, Kwang-Gill;Yeo, Joo-Hong;Kang, Pil-Don;Nam, Sung-Hee;Park, Kwang-Young;Kim, Mi-Ja;Park, Myung-Ki;Son, Yong-Ho;Kim, Sung-Hyun;Kim, Sang-Gyu;Im, Sung-Bin;Choi, Byung-Hoon;Ha, Soo-Yeon;Lee, Heui-Sam
    • Journal of Sericultural and Entomological Science
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    • v.50 no.1
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    • pp.20-26
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    • 2012
  • In this study, silk gland powder of silkworm were investigated to see the possibility for baby powder cosmetics materials. To test possibility as a baby powder cosmetics, total content rate of amino acids, DPPH free radical scavenging assay, MTT assay, and clinical trial were done. According to the result of the analysis of the amino acids of silk gland powder, serin (26.77%) content was the highest and asparatic acid (15.47%), and glycine (9.62%) were followed. DPPH free radical scavenging activity of silk gland powder was lower than vitamin C by 82.3% and 97%, respectively, which is relatively good. Moisture effect were increased in silk gland powder compared to control cosmetics by 50%. Also, silk gland powder was classified as a practically non-irritating material based on the score 0.05 of primary irritation index. Thus, these results suggest that silk gland powder of silkworm may have beneficial properties as a material for baby powder cosmetics.

Clients' Handling and Consumption of Home-delivered Meals at Home and Their Perceptions on Home-Delivered Meal Services for Older Adults (노인급식 수혜자의 가정에서 배달 도시락 취급 및 섭취 실태와 가정배달 급식서비스에 대한 인식)

  • Park, Jung-Yeon;Lee, Kyung-Eun;Yi, Na-Young;Kwak, Tong-Kyung
    • Korean Journal of Community Nutrition
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    • v.15 no.3
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    • pp.379-392
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    • 2010
  • The purposes of this study were to investigate recipients' handling and consumption of home-delivered meals at home and to assess their perceptions on home-delivered meal services for older adults. A total of 312 elderly people who received home-delivered foodservice were surveyed using an individual interview technique. A statistical data analysis was completed using SPSS (ver. 14.0). It was found that 90.2% (n = 166) of the lunch box recipients received services for six days per week, and 76.6% (n = 95) of the side-dish recipients got services once per week. More than half of the clients reported that they cooked meals by themselves on days when meals were not delivered. The two hundred thirty-two (75.3%) ate their meals as soon as they were delivered. It was found that 66.8% of the lunch box recipients and 7.3% of the side-dish recipients left delivered meals on the counter (at room temperatures) before eating. Only 11.4% of the lunch box recipients and 48.4% of the side-dish recipients kept delivered meals in the refrigerator before eating. Less than half of the lunch box recipients consumed all foods they were served at once. The reasons the recipients did not eat their all meals delivered at once were "saving for next meals" and "big portion size" Of those clients who left delivered meals, 19% of the lunch box recipients and 9.7% of the side-dish recipients ate leftovers without reheating. An average score of quality of delivered meal services was 3.5 out of 5 points. The results suggest that the clients of the home-delivered meal service should be provided information on proper handling and consumption practices with delivered meals at home. The findings of the study will be used to develop nutrition and food safety management guidelines for senior foodservice.

Mobility Evaluation of Popular Firefighting Protective Gloves in Domestic and Foreign Countries -Don-Doff Test, Dexterity Test, and Torque Test- (국내외 보급형 소방용 보호장갑의 동작성 평가 -착탈 시험, 기민성 시험, 회전력 시험을 중심으로-)

  • Kim, Dami;Lee, Inseong;Lee, Joo-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.40 no.5
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    • pp.921-935
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    • 2016
  • This research analyzed the manual performance of firefighting protective gloves on global markets in order to suggest an evaluation method for firefighting protective gloves wearing comfort. We collected 13 types of firefighting gloves from domestic and international markets (7 types from Korea, 3 types form Europe, 2 types from the U.S and 1 type from Japan). We set the Don-Doff test as a basal requirement for moving toward to further manual performance tests that consist of: ASTM dexterity test, Minnesota dexterity test, Bennett hand tool test and ASTM torque test. All gloves were evaluated in dry and wet conditions, we included eight current male firefighters ($43.4{\pm}7.0yr$ in age, $173.1{\pm}4.4cm$ in height, $79.9{\pm}9.2kg$ in body mass) for the tests. Four gloves (1 Korea, 1 U.S, 1 Germany, and 1 Japan) out of thirteen firefighting gloves passed the Don-Doff test and had great subject preferences. There was no significant difference between dry and wet conditions on the ASTM dexterity test, Minnesota dexterity test, Bennett hand tool test and ASTM torque test. However, Japanese gloves had the greatest score and showed 3-4 times faster completion time on the ASTM dexterity test (p<.05), 1.2-1.5 times faster on the Minnesota dexterity test (p<.05), as fast as the bare hand on Bennett hand tool test (p<.05), and greater performance on the ASTM torque test compared to bare hand. In conclusion, Don-Doff test in wet conditions should be the first step for a mobility evaluation of domestic firefighting protective gloves; subsequently, a comprehensive test assorting ASTM, Minnesota, and Bennett test should be developed as a second step. The current ASTM torque test can be adopted as a third step. This three-step-method for evaluating firefighting protective glove mobility can be expected to expand into surveys of other safety gloves in Korea.

Development of Vegetation Indicator for Assessment of Naturalness in Stream Environment (하천환경의 자연성 평가를 위한 식생지표의 개발)

  • Chun, Seung-Hoon;Chae, Soo-Kwon
    • Journal of Environmental Impact Assessment
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    • v.25 no.6
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    • pp.384-401
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    • 2016
  • The vegetation assessment indicator has been developed recently as a biological part of the integrated assessment system for river environment to improve the efficiency of river restoration projects. This study carried out to test the vegetation assessment indicator and to reset its grade criteria on experimental streams. We classified and mapped vegetation communities at the level of physiognomic-floristic composition by each assessment unit. A total of 204 sampling quadrats were set up on the 68 assessment units at 5 experimental streams. By analyzing the vegetation data collected, we examined the appropriate numbers of sampling quadrats, the criteria of vegetation index score, classification of vegetation community, and grade criteria for vegetation assessment. The developed vegetation assessment indicator composed with the vegetation complexity index (VCI), the vegetation diversity index (VDI), and the vegetation naturalness index (VNI) was proved to reflect the current conditions of the streams sufficiently. The contribution of vegetation naturalness index to grading by vegetation assessment indicator was larger, but three indexes were closely correlated to each other. Also there was more clearer discrimination of grading with the application of adjusted criteria of vegetation assessment indicator and the standardized classification of vegetation community, but the stream segment type did not influence the vegetation assessment grade significantly.