• Title/Summary/Keyword: safe use

Search Result 2,035, Processing Time 0.029 seconds

Effects and safety of COVID-19 vaccination on assisted reproductive technology and pregnancy: A comprehensive review and joint statements of the KSRM, the KSRI, and the KOSAR

  • Han, Ae Ra;Lee, Dayong;Kim, Seul Ki;Choo, Chang Woo;Park, Joon Cheol;Lee, Jung Ryeol;Choi, Won Jun;Jun, Jin Hyun;Rhee, Jeong Ho;Kim, Seok Hyun;Korean Society for Reproductive Medicine (KSRM),;Korean Society for Reproductive Immunology (KSRI),;Korean Society for Assisted Reproduction (KOSAR),
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.49 no.1
    • /
    • pp.2-8
    • /
    • 2022
  • Humanity is in the midst of the coronavirus disease 2019 (COVID-19) pandemic, and vaccines-including mRNA vaccines-have been developed at an unprecedented speed. It is necessary to develop guidelines for vaccination for people undergoing treatment with assisted reproductive technology (ART) and for pregnancy-related situations based on the extant laboratory and clinical data. COVID-19 vaccines do not appear to adversely affect gametes, embryos, or implantation; therefore, active vaccination is recommended for women or men who are preparing for ART. The use of intravenous immunoglobulin G (IVIG) for the treatment of immune-related infertility is unlikely to impact the effectiveness of the vaccines, so COVID-19 vaccines can be administered around ART cycles in which IVIG is scheduled. Pregnant women have been proven to be at risk of severe maternal and neonatal complications from COVID-19. It does not appear that COVID-19 vaccines harm pregnant women or fetuses; instead, they have been observed to deliver antibodies against severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) to the fetus. Accordingly, it is recommended that pregnant women receive COVID-19 vaccination. There is no rationale for adverse effects, or clinical cases of adverse reactions, in mothers or neonates after COVID-19 vaccination in lactating women. Instead, antibodies to SARS-CoV-2 can be delivered through breast milk. Therefore, breastfeeding mothers should consider vaccination. In summary, active administration of COVID-19 vaccines will help ensure the safe implementation of ART, pregnancy, and breastfeeding.

Differences of Teachers and Students' Perceptions on Teaching Skills (교사의 수업전문성에 관한 교사와 학생의 인식 차이)

  • Lee, Okhwa
    • Korean Educational Research Journal
    • /
    • v.43 no.1
    • /
    • pp.125-152
    • /
    • 2022
  • The purpose of this study is to examine the differences of perceptions of teachers and students regarding teaching skills. For the analysis, data was collected by ICALT(International Comparative Analysis of Learning and Teaching) class observation tool and students survey called My Teacher Questionnaire. a student survey. The data of teachers and students can be compared because as the two tools have seven common domains(Safe and stimulating learning climate, Efficient organization, Clear and structured instructions, Intensive and activating teaching, Adjusting instructions and learner processing to inter-learner differences, Teaching learning strategies, Learner engagement). In 2016, in Daejeon, Chungbuk and Chungnam. trained teachers collected data from 106 classes, and 2,866 students responded the survey. The reliability and validity of the two tools, class observation and MTQ(My Teacher Questionnaire) are proven to be satisfactory for use in Korean schools. Students perception on teaching was high, particularly when students are in lower grades and learning major subjects like English, Korean, and math. The domain of higher teaching skills, male students show higher perceptions while female students reported higher perceptions on lower-level teaching skill domains. To compare the perceptions of teachers and students, the predictive reliability of students engagement against teaching skill domains was used. Teachers showed higher predictive reliability on lower teaching skill domains while students showed higher predictive reliability on higher teaching skill domains. It is recommended for further study to develop a professional development model using a teacher class observation tool and the My Teacher Questionnaire for pre-service teachers and school teachers.

Multi-fidelity uncertainty quantification of high Reynolds number turbulent flow around a rectangular 5:1 Cylinder

  • Sakuma, Mayu;Pepper, Nick;Warnakulasuriya, Suneth;Montomoli, Francesco;Wuch-ner, Roland;Bletzinger, Kai-Uwe
    • Wind and Structures
    • /
    • v.34 no.1
    • /
    • pp.127-136
    • /
    • 2022
  • In this work a multi-fidelity non-intrusive polynomial chaos (MF-NIPC) has been applied to a structural wind engineering problem in architectural design for the first time. In architectural design it is important to design structures that are safe in a range of wind directions and speeds. For this reason, the computational models used to design buildings and bridges must account for the uncertainties associated with the interaction between the structure and wind. In order to use the numerical simulations for the design, the numerical models must be validated by experi-mental data, and uncertainties contained in the experiments should also be taken into account. Uncertainty Quantifi-cation has been increasingly used for CFD simulations to consider such uncertainties. Typically, CFD simulations are computationally expensive, motivating the increased interest in multi-fidelity methods due to their ability to lev-erage limited data sets of high-fidelity data with evaluations of more computationally inexpensive models. Previous-ly, the multi-fidelity framework has been applied to CFD simulations for the purposes of optimization, rather than for the statistical assessment of candidate design. In this paper MF-NIPC method is applied to flow around a rectan-gular 5:1 cylinder, which has been thoroughly investigated for architectural design. The purpose of UQ is validation of numerical simulation results with experimental data, therefore the radius of curvature of the rectangular cylinder corners and the angle of attack are considered to be random variables, which are known to contain uncertainties when wind tunnel tests are carried out. Computational Fluid Dynamics (CFD) simulations are solved by a solver that employs the Finite Element Method (FEM) for two turbulence modeling approaches of the incompressible Navier-Stokes equations: Unsteady Reynolds Averaged Navier Stokes (URANS) and the Large Eddy simulation (LES). The results of the uncertainty analysis with CFD are compared to experimental data in terms of time-averaged pressure coefficients and bulk parameters. In addition, the accuracy and efficiency of the multi-fidelity framework is demonstrated through a comparison with the results of the high-fidelity model.

Optimizing Fat Grafting Using a Hydraulic System Technique for Fat Processing: A Time and Cost Analysis

  • Verdura, Vincenzo;Guastafierro, Antonio;Di Pace, Bruno;Faenza, Mario;Nicoletti, Giovanni Francesco;Rubino, Corrado
    • Archives of Plastic Surgery
    • /
    • v.49 no.2
    • /
    • pp.266-274
    • /
    • 2022
  • Background Many authors have researched ways to optimize fat grafting by looking for a technique that offers safe and long-term fat survival rate. To date, there is no standardized protocol. We designed a "hydraulic system technique" optimizing the relationship among the quantity of injected fat, operative time, and material cost to establish fat volume cutoffs for a single procedure. Methods Thirty-six patients underwent fat grafting surgery and were organized into three groups according to material used: standard, "1-track," and "2-tracks" systems. The amount of harvested and grafted fat as well as material used for each procedure was collected. Operating times were recorded and statistical analysis was performed to establish the relationship with the amount of treated fat. Results In 15 cases the standard system was used (mean treated fat 72 [30-100] mL, mean cost 4.23 ± 0.27 euros), in 11 cases the "1-track" system (mean treated fat 183.3 [120-280] mL, mean cost 7.63 ± 0.6 euros), and in 10 cases the "2-tracks" one (mean treated fat 311[220-550] mL, mean cost 12.47 ± 1 euros). The mean time difference between the standard system and the "1-track" system is statistically significant starting from three fat syringes (90 mL) in 17.66 versus 6.87 minutes. The difference between the "1-track" system and "2-tracks" system becomes statistically significant from 240 mL of fat in 15 minutes ("1-track") versus 9.3 minutes for the "2-tracks" system. Conclusion Data analysis would indicate the use of the standard system, "1-track," and "2-tracks" to treat an amount of fat < 90 mL of fat, 90 ÷ 240 mL of fat, and ≥ 240 mL of fat, respectively.

A Study on the Perception of NGO's Overseas Service Experience: With Professional Retirees at the Center (NGO 해외봉사 경험에 대한 인식 연구: 전문직 은퇴자를 중심으로)

  • Chung, Ju-Young;Lee, Mi-Ran
    • Journal of Digital Convergence
    • /
    • v.19 no.11
    • /
    • pp.31-38
    • /
    • 2021
  • The use of professional retirement personnel who have largely left their economic activities due to the retirement of baby boomers is a modern task and is emerging as a social issue. This study aims to explo re the perception of professional retirees' overseas volunteer experience as NGOs and seek ways to utilize pro fessional retirement personnel. This study is a qualitative study using photo-voice, and the participants in the study are retirees of retirement age from professions with experience in NGO overseas service. Data were collected through group activities and individual interviews, and data were analyzed using participatory analysis and subject analysis. The perception derived from the study was that NGO overseas service is the best job to be safe and raise the national status, and that information on this is wanted to be provided in retirement education. In conclusion, retirement education for the expansion of NGO overseas service was conducted not only in public enterprises but also in general workplaces to discuss ways to prepare before retirement, and the operation of the Retired NGO Overseas Volunteer Information Service Center was suggested. This study is meaningful in presenting basic data for preparing alternatives to social welfare policies in old age after retirement through the recognition of the experience of professional retirees in overseas NGO service

Content Analysis of the 'Housing' Unit in the 2015 Revised Middle School Technology and Home Economics Textbook Using Text Mining (텍스트 마이닝을 이용한 2015 개정 중학교 기술·가정 교과서의 주생활 단원 내용분석)

  • Kim, Do-Yeon
    • Journal of Korean Home Economics Education Association
    • /
    • v.34 no.2
    • /
    • pp.1-19
    • /
    • 2022
  • The purpose of this study is to analyze the keywords of the middle school textbooks based on the 2015 revision of the technology and home economics curriculum to understand the core concepts and contents composition of the 'housing' unit. Using TEXTOM and UCINET programs, the frequencies and centralities of the keywords were analyzed, and CONCOR analysis was performed. The results are as follows. First, the content system of the 'housing' unit is divided into 'life culture' and 'safety' in the 'family life and safety' area. Second, in the 'safety' section, the frequencies of occurrence of the words were high in the order of indoor, occurrence, use, noise, and safety accidents, in the order of frequency of occurrence. It was confirmed that words related to daily life, safety accidents, and prevention were closely connected to each other. In the 'life culture' section, the frequencies of occurrence were high in the order of space, housing, family, and residential space, and the correlations between these keywords were also high. Third, the most influential core keywords were, indoor and occurrence in the 'safety' section, and space, family, and housing, in the 'life culture' section. Fourth, the 'safety' section were divided into two subunits, 'safe living environment' and 'comfortable living environment', and the 'life culture' section were divided into four subunits, 'living space composition', 'space utilization', 'housing value and lifestyle', and 'housing culture'.

Improvement Mechanism for Automatic Web Vulnerability Diagnosis (웹취약점 자동진단 개선방안)

  • Kim, Tae-Seop;Jo, In-June
    • The Journal of the Korea Contents Association
    • /
    • v.22 no.2
    • /
    • pp.125-134
    • /
    • 2022
  • Due to the development of smartphone technology, as of 2020, 91.9% of people use the Internet[1] to frequently acquire information through websites and mobile apps. As the number of homepages in charge of providing information is increasing every year, the number of applications for web vulnerability diagnosis, which diagnoses the safety of homepages, is also increasing. In the existing web vulnerability check, the number of diagnostic personnel should increase in proportion to the number of homepages that need diagnosis because the diagnosticians manually test the homepages for vulnerabilities. In reality, however, there is a limit to securing a web vulnerability diagnosis manpower, and if the number of diagnosis manpower is increased, a lot of costs are incurred. To solve these problems, an automatic diagnosis tool is used to replace a part of the manual diagnosis. This paper explores a new method to expand the current automatic diagnosis range. In other words, automatic diagnosis possible items were derived by analyzing the impact of web vulnerability diagnosis items. Furthermore, automatic diagnosis identified possible items through comparative analysis of diagnosis results by performing manual and automatic diagnosis on the website in operation. In addition, it is possible to replace manual diagnosis for possible items, but not all vulnerability items, through the improvement of automatic diagnosis tools. This paper will explore some suggestions that can help improve plans to support and implement automatic diagnosis. Through this, it will be possible to contribute to the creation of a safe website operating environment by focusing on the parts that require precise diagnosis.

CycleGAN Based Translation Method between Asphalt and Concrete Crack Images for Data Augmentation (데이터 증강을 위한 순환 생성적 적대 신경망 기반의 아스팔트와 콘크리트 균열 영상 간의 변환 기법)

  • Shim, Seungbo
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.21 no.5
    • /
    • pp.171-182
    • /
    • 2022
  • The safe use of a structure requires it to be maintained in an undamaged state. Thus, a typical factor that determines the safety of a structure is a crack in it. In addition, cracks are caused by various reasons, damage the structure in various ways, and exist in different shapes. Making matters worse, if these cracks are unattended, the risk of structural failure increases and proceeds to a catastrophe. Hence, recently, methods of checking structural damage using deep learning and computer vision technology have been introduced. These methods usually have the premise that there should be a large amount of training image data. However, the amount of training image data is always insufficient. Particularly, this insufficiency negatively affects the performance of deep learning crack detection algorithms. Hence, in this study, a method of augmenting crack image data based on the image translation technique was developed. In particular, this method obtained the crack image data for training a deep learning neural network model by transforming a specific case of a asphalt crack image into a concrete crack image or vice versa . Eventually, this method expected that a robust crack detection algorithm could be developed by increasing the diversity of its training data.

Developing national level high alert medication lists for acute care setting in Korea (국내 급성기 의료기관 고위험 의약품 목록 도출)

  • Han, Ji Min;Heo, Kyu-Nam;Lee, Ah Young;Min, Sang il;Kim, Hyun Jee;Baek, Jin-Hee;Rho, Juhyun;Kim, Sue In;Kim, Ji yeon;Lee, Haewon;Cho, Eunju;Ah, Young-Mi;Lee, Ju-Yeun
    • Korean Journal of Clinical Pharmacy
    • /
    • v.32 no.2
    • /
    • pp.116-124
    • /
    • 2022
  • Background: High-alert medications (HAMs) are medications that bear a heightened risk of causing significant patient harm if used in error. To facilitate safe use of HAMs, identifying specific HAM lists for clinical setting is necessary. We aimed to develop the national level HAM list for acute care setting. Methods: We used three-step process. First, we compiled the pre-existing lists referring HAMs. Second, we analyzed medication related incidents reported from national patient safety incident report data and adverse events indicating medication errors from the Korea Adverse Event Reporting System (KAERS). We also surveyed the assistant staffs to support patient safety tasks and pharmacist in charge of medication safety in acute care hospital. From findings from analysis and survey results we created additional candidate list of HAMs. Third, we derived the final list for HAMs in acute care settings through expert panel surveys. Results: From pre-existing HAM list, preliminary list consisting of 42 medication class/ingredients was derived. Eight assistant staff to support patient safety tasks and 39 pharmacists in charge of medication safety responded to the survey. Additional 44 medication were listed from national patient safety incident report data, KAERS data and common medications involved in prescribing errors and dispensing errors from survey data. A list of mandatory and optional HAMs consisting of 10 and 6 medication classes, respectively, was developed by consensus of the expert group. Conclusion: We developed national level HAM list for Korean acute care setting from pre-existing lists, analyzing medication error data, survey and expert panel consensus.

The Chronic and Acute Toxicity of Traditional Medicines Containing Terminalia chebula

  • ARONGQIQIGE ARONGQIQIGE;Gerelmaa Enebish;Wang Song;Wei Cheng Xi;Anuujin Gantumur;Oyunbaatar Altanbayar;Hirofumi Shimomura;Battogtokh Chimeddorj;Batnairamdal Chuluun;Avarzed Amgalanbaatar
    • Journal of Pharmacopuncture
    • /
    • v.26 no.1
    • /
    • pp.18-26
    • /
    • 2023
  • Objectives: Terminalia chebula, the main ingredient of Altan Arur 5, has been used for many years in traditional medicine. This medicine is more effective than other drugs and is used to treat chronic gastritis and gastrointestinal disorders such as peptic ulcers and esophageal reflux. Other ingredients of Altan Arur 5 are Punica granatum (pomegranate), tulip seeds, black balm, and excreta of Trogopterus xanthipes. The main ingredients of T. chebula are antibacterial and analgesic in traditional medicine. Despite having been used for many years and although many studies have been conducted on the beneficial effects of this medicine and its ingredients, the toxicity of Altan Arur 5 has not yet been elucidated. Therefore, we aimed to study the toxicity of Altan Arur 5 to ensure that it is safe to use. Methods: Acute and chronic toxicity of Altan Arur 5 were assessed in 10 Kunming mice and 8 Sprague-Dawley rats, respectively, in different doses. In the acute toxicity study, Altan Arur 5 was orally administered to Kunming mice in doses of 12 g/kg, 24 g/kg, and 48 g/kg for 14 days. In the chronic toxicity study, it was orally administered to Sprague-Dawley rats in doses of 1.25 g/kg, 2.5 g/kg, and 5 g/kg for 12 weeks. Results: No significant differences were observed in the relative organ weights for mice treated with Altan Arur 5 compared with those in the control group. Furthermore, no macro- or microstructural changes were noted in the organs of any group. Conclusion: Our toxicity testing revealed that the traditional medicine Altan Arur 5 has no toxic effects in vivo.