• Journal of Sasang Constitutional Medicine
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• v.21 no.1
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• pp.247-253
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• 2009

1. Objectives This study was designed to andyze the acute toxicity and safety of Yeoldahanso-tang 2. Methods We investigated the acute toxicity for water-extracted Yeoldahanso-tang. 25 male and 25 female mice were observed for 14 days after one day oral administration of Yeoldahanso-tang at the respective doses of 0(control group), 2560, 3200, 4000 and 5000 mg/kg. 3. Results We observed survival rates, general toxicity, change of body weight and autopsy. 4. Conclusions The data confirmed that Yeoldahanso-tang is free from the toxicity and safety problems in oral route respectively. Compared with the control group, we could not find any toxic alteration in all treated groups(2560, 3200, 4000 and 5000 mg/kg). In conclusion, LD50 of Yeoldahanso-tang was over 5000 mg/kg and it is very safe to mice.

• Environmental Engineering Research
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• v.24 no.4
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• pp.566-571
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• 2019

One-pot hydrothermal route was adopted to synthesize Al:BiVO₄, at 4 h and 8 h reaction durations, by adding 1% aluminiumoxide powder (w/v) to the precursors. The products were investigated using several characterization techniques that conform a significant morphological change and a decrease in bandgap energy of the materials upon Al modification of scheelite monoclinic bismuth vanadate matrix at both hydrothermal durations. Antibacterial experiments were performed against methicillin-resistant Staphylococcus aureus in visible light condition to harness the photoxidation property of Al-doped BiVO₄ and compare to that of unaltered BiVO₄. Minimum inhibitory concentration of the synthesized materials was identified. The results indicate that Al-doping on BiVO₄ has a significant effect on its photocatalytic antibacterial performance. Al:BiVO₄ synthesized at 8 h hydrothermal treatment parades excellent sunlight-driven photocatalysis compared to the one synthesized at 4 h.

• Journal of Navigation and Port Research
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• v.30 no.7
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• pp.585-590
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• 2006

Though the issue on the integration of maritime transport market in Northeast Asia has a long history, there has never been any notable progress. Especially the lack of country-wise analysis on the barriers of market integration appears as a serious problem for more concrete discussion and the design of the roadmap for market integration. This study analyzes the maritime market of each country in the aspect of infrastructure provision, the development of the industry, change of institutions, and network connectivity and compare the competitiveness of 3 countries in the Northeast maritime market. Furthermore this study analyzes the barriers for market integration on the basis of bilateral relation, i.e. Korea-Japan, Korea-China and Japan-Korea. Based on these analyses, this study finds out the fact that the most serious barrier for market integration among 3 countries is the egocentric policies for the protection of industries in each country rather than any other institutional or physical barriers. In conclusion, this study argues that 3 countries should try to find out a third policy alternative which can make 3 countries enjoy the win-win game, such as route integration among 3 countries and joint venture for the liners operated in the region.

• The Transactions of the Korea Information Processing Society
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• v.6 no.9
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• pp.2442-2450
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• 1999

The audit logging system is to write the details of systems use and access on networks. These details are used for trailing the route, when illegal access or using system resource is occurred on networks. The logging system therefore, might be the first target of intruder. We developed the logging system which writes the information of logging and command execution on UNIX system. And we prepared the self-protecting functions of blocking intruder's attack on the logging system. They are protecting the logging process and the log file. To protect the logging process, we made it keep changing the process ID to avoid the intruder's attack. To protect the log file, we use hard link and mandatory file locking, so it can make it impossible to delete or change log file.

• Journal of The Korean Society of Agricultural Engineers
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• v.46 no.1
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• pp.121-131
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• 2004

Transportation and logistics of agricultural products have been one of the major interests of many researches. Most of researches have been limited to presuming these as a first dimensional process or considering only economic value of agricultural products at each stage of logistics. However, the particular characteristics of agricultural products, such as quality change during transportation or extensively scattered origins, require examining these problems as a whole system. Network model has been adopted to represent nodes, which stand for spatial location of demand and supply of agricultural products, and communication between these nodes. Based on network theory and advanced marketing potential function, an optimal routes selection model is developed. The model employed network simplex method for routes optimization. The application of the model focused on transportation network organization to reflect different market prices for different locations and resulted in optimum routes and profit improvement of the applied agricultural product.

• Journal of the Korean Institute of Navigation
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• v.19 no.1
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• pp.33-48
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• 1995

In the process of containerization, the problem of regional maldistribution of container management plan arises seriously due to several factors like a number of unbalances of containers between loading and discharging ports. This study focus on the minimizing cost. This study is composed of two models which in effective management decision making show decision of the number of containers and transfer of empty containers. One is decision of the number of containers which carriers should possess by appropriate forecasting and the other is effective management decision making which includes the transfer of empty containers on calling ports. This study has suggested as follows, First, the Time Series analysis method, especially the "Exponential Smooting with Trend Adjustment" was used to forecast the trade volumes for the designated traffic route. Second, the Time Series analysis method in deciding the optimal number of owned container at the unbalances trade situation between East Bound and West Bound service, most important variables were found such as total traffic volume, the calling interval at a port, the number of days of voyage and the length of stay on shore of container for the optimal number of owned container. Third, effective management decision making model, which makes it possible to analyze the impacts of change in important matters such as lease and positioning policy, and actually influence decision making.on making.

• Korean Journal of Materials Research
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• v.26 no.2
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• pp.61-66
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• 2016

In order to fabricate porous mullite ceramics with controlled pore structure and improved mechanical strength, a freeze casting route has been processed using camphene mixed with tertiary-butyl alcohol (TBA) and coal fly ash/alumina as the solvent and the ceramic material, respectively. After sintering, the solidification characteristics of camphene and TBA solvent were evident in the pore morphology, i.e., dendritic and straight pore channels formed along the solidification directions of camphene and TBA ice, respectively, after sublimation. Also, the presence of microcracks was observed in the bodies sintered at $1500^{\circ}C$, mainly due to the difference in solidification volume change between camphene and TBA. The compressive strength of the sintered bodies was found generally to be dependent, in an inverse manner, on the porosity, which was mainly determined by the processing conditions. After sintering at $1300{\sim}1500^{\circ}C$ with 30~50 wt% solid loading, the resulting mullite ceramics showed porosity and compressive strength values in ranges of 83.8~43.1% and 3.7~206.8 MPa, respectively.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.12
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• pp.3081-3099
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• 2012

We propose a new multipath-based reliable routing protocol on MANETs, Multipath-based Reliable routing protocol with Fast-Recovery of failures (MRFR). For reliable message transmission, MRFR tries to find the most reliable path between a source and a destination considering the end-to-end packet reception reliability of the routes. The established path consists of a primary path that is used to transmit messages, and the secondary paths that are used to recover the path when detecting failures on the primary path. After establishing the path, the source transmits messages through the primary path. If a node detects a link failure during message transmission, it can recover the path locally by switching from the primary to the secondary path. By allowing the intermediate nodes to locally recover the route failure, the proposed protocol can handle the dynamic topological change of the MANETs efficiently. The simulation result using the QualNet simulator shows that the MRFR protocol performs better than other protocols in terms of the end-to-end message delivery ratio and fault-tolerance capability.

• Archives of Pharmacal Research
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• v.8 no.3
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• pp.177-186
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• 1985

Effect of food on the absorption characteristics of oral rifampicin was studied in the fasted rats. Rifampicin dissolved in a new cosolvent was also injected to the rats intravenously, and the pharmacokinetic analysis was performed to explain the effect of food on the gastrointestinal absorption of rifampicin. Rifampicin was absorbed rapidly and completely in the fasting state. Food had a profound effect on the gastrointestinal absorption of rifampicin, i. e., bioavailability and the extent of absorption were decreased to less than one-third of the fasting state in the postprandial state. Food seemed to imhibit the absorption and reabsorption of rifampicin in the gastrointestinal tract, but not the absorption rate constant. Hepatobiliary excretion seemed to be the major route of elimination, since the renal clearance accounted for only 8 % of the systemic clearance. Nevertheless, first-pass effect was negligibly small and most of rifampicin absorbed could reach systemic circulation. Serum concentration change of oral rifampicin on multiple dosing differed markedly in the fasting and postprandial state, which suggested the need of careful adjustment of dosage regimen in both states.

• Journal of the Korean Society of Industry Convergence
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• v.24 no.6_2
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• pp.883-890
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• 2021

In this study, joint analysis was conducted on the rock slope by aerial surveying using UAV. Aerial photos were taken using UAV to measure the directionality of the rock slope exposed to the site, and the directionality of the joint was analyzed using the photographed photos. UAV photography was taken under conditions of 90% overlap and an altitude of 50m. The photographing path was measured in the horizontal, vertical, and oblique directions based on the slope, and the joint characteristics were analyzed. Aerial surveying research on the joint directionality analysis of rock slopes is still incomplete, and the method for accurate joint directionality analysis is not presented strategically, so it is difficult to apply it in design. Through the results of this study, we would like to propose an flight photographing technique for the investigation of rock joints. As a result of the study, in the case of the joint investigation of the rock slope using UAV, it was necessary to change conditions such as altitude, aerial photography route, and overlap according to the size of the joint according to the site conditions.