• 한국압력기기공학회 논문집
• /
• 제9권1호
• /
• pp.62-69
• /
• 2013

A probabilistic assessment code, PRO-LOCA ver. 3.7 which was developed in an international co-operative research program, PARTRIDGE was evaluated by conducting sensitivity analysis. The effect of some variables such as simulation methods (adaptive sampling, iteration numbers, weld residual stress model), crack features(Poisson's arrival rate, maximum numbers of cracks, initial flaw size, fabrication flaws), operating and loading conditions(temperature, primary bending stress, earthquake strength and frequency), and inspection model(inspection intervals, detectable leak rate) on the failure probabilities of a surge line nozzle was investigated. The results of sensitivity analysis shows the remaining problems of the PRO-LOCA code such as the instability of adaptive sampling and unexpected trend of failure probabilities at an early stage.

• Journal of Genetic Medicine
• /
• 제12권2호
• /
• pp.96-99
• /
• 2015

Purpose: To evaluate the performance of the Momguard noninvasive prenatal test by tracing the 'screen positive' results based on preliminary samples from Korean cohorts. Materials and Methods: This preliminary study is based on data collected by the LabGenomics Clinical Laboratory (Seongnam, Korea) with informed consent. Only pregnant women who underwent both the Momguard test and karyotyping were included in this study. Momguard test results were compared with those of the karyotyping analysis. Results: Among the 38 cases with 'screen positive' results by Momguard, 30 cases also had karyotyping results available. In three trisomy (T) 18 and three T13 cases, the Momguard results were concordant with the karyotyping results. For the T21 cases, except for one case belonging to the mid-risk zone, Momguard results from 23 out of 24 cases matched the karyotyping results. Conclusion: Momguard is a highly reliable screening tool for detecting T13, T18, and T21 cases in independent Korean cohort samples.

• Nuclear Engineering and Technology
• /
• 제49권2호
• /
• pp.349-359
• /
• 2017

During the past 25 years, in the context of probabilistic safety assessment, efforts have been directed towards establishment of comprehensive pipe failure event databases as a foundation for exploratory research to better understand how to effectively organize a piping reliability analysis task. The focused pipe failure database development efforts have progressed well with the development of piping reliability analysis frameworks that utilize the full body of service experience data, fracture mechanics analysis insights, expert elicitation results that are rolled into an integrated and risk-informed approach to the estimation of piping reliability parameters with full recognition of the embedded uncertainties. The discussion in this paper builds on a major collection of operating experience data (more than 11,000 pipe failure records) and the associated lessons learned from data analysis and data applications spanning three decades. The piping reliability analysis lessons learned have been obtained from the derivation of pipe leak and rupture frequencies for corrosion resistant piping in a raw water environment, loss-of-coolant-accident frequencies given degradation mitigation, high-energy pipe break analysis, moderate-energy pipe break analysis, and numerous plant-specific applications of a statistical piping reliability model framework. Conclusions are presented regarding the feasibility of determining and incorporating aging effects into probabilistic safety assessment models.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권2호
• /
• pp.853-857
• /
• 2013

Objectives: Breast cancer is a leading cause of morbidity and mortality in women worldwide. Breast screening in normal and/or asymptomatic women is essential to reduce the burden of breast malignancies. Our study aimed to identify possible risk- and/or co-factors associated with breast screening in North Indian women. Methods: A public health research survey was conducted among 100 women of North Indian ethnicity during clinic visits in a 6-month timeline (April-October 2012). Demographic and clinical data, including mammography screening, were recorded in the questionnaire-based proforma after conducting a 10 minute interview. Written informed consent was taken from all the participants. Results: The mean age of the participants was $32.2{\pm}9.9$ years. Out of 100 women, 6% had family history of breast disease. Breast-related complaints/malignancy, including galactorrhoea, mastitis, axillary lump, fibrocystic disease, fibroadenosis and adenocarcinoma were observed in 41% participants; age stratification revealed that 82.9% of this group (n=41) were <30 years, while 9.7% and 7.3% were >30 years and 30 years of age, respectively. 32% participants underwent mammography screening and 8% had breast ultrasound imaging. Age stratification in the mammography screening group demonstrated that 24 women were <40 years, while 7 women were >40 years. Conclusions: Our pilot study identified possible co-factors affecting breast screening in North Indian women. These findings may be beneficial in early detection of breast abnormalities, including malignancies in women susceptible to breast cancer, and thus aid in future design of cost-effective screening strategies to reduce the increasing burden of breast carcinoma in women worldwide.

• 한국콘텐츠학회:학술대회논문집
• /
• 한국콘텐츠학회 2017년도 춘계 종합학술대회 논문집
• /
• pp.471-472
• /
• 2017

There are 3,931,822 elderly who receives long-term care at home and 1,704,469 elderly who stay at long-term care facilities in those of 34,610,000 of +65 years old population in Japan; thus, the elderly people who need home care are 2.3 times more than facilities (2016).In the near future, the number of elderly people with a degree of daily life independence and dementia category II or more will increase to 4.7 million (12.8% of the elderly population). Therefore, the use of home-care robots is essential for the disaster evacuation of the overwhelming majority of those elderly who need home care and for of vitals checks to keep family, caregivers, and medical professionals informed to reduce the risk in chronic health conditions in welfare evacuation centers. This also helps to care for the caregivers who are caring for the elderly, and the introduction of home-robots to evacuation centers should receive prompt attention from our care-friendly society.

• 대한물리의학회지
• /
• 제6권2호
• /
• pp.145-151
• /
• 2011

Purpose: The study was designed to investigate the effects of landing heights on muscle activities and ground reaction force during drop landing. Methods: Sixteen healthy adults were recruited along with their written informed consent. They performed a drop-landing task at the height of 20, 40, and 60cm. They completed three trials in each condition and biomechanical changes were measured. The data collected by each way of landing task and analyzed by One-way ANOVA. Ground reaction forces were measured by force flate, muscle activities measured by MP150 system. Results: There were significant differences in ground reaction forces, and significant increases in muscle activities of tibialis anterior, medial gastrocnemius and biceps femoris with landing heights. Conclusion: These findings revealed that heights of landing increases risk factors of body damage because of biomechanical mechanism and future studies should focus on prevention from damage of external conditions.

• 한국치위생학회지
• /
• 제13권3호
• /
• pp.525-534
• /
• 2013

Objectives : This study aimed to improve school health program by investigation of several variables through educational diagnostic factors which influence the level of subjective oral health perception and DMFT of students on the basis of PRECEDE model. Methods : A total of 286 high school students in Busan completed the self-reported questionnaire from September 3 to 28 in 2012. Results : 1. Social and epidemiologic diagnosis suggested that the level of subjective oral health perception of male students was not better than that of female students and DMFT number of the male was more than that of the female(p<0.001)(p<0.001). 2. Oral health diagnosis indicated that once a day tooth brushing group showed lower level of oral health perception(p<0.001) and high DMFT number(p<0.001). 3. Predisposing factor of educational diagnosis implied that more than 4 times a day snack intake group and sweet diet and soda friendly group showed lower level of oral health perception and high DMFT number(p<0.001). 4. Tooth brushing of the reinforcing factors had the most important effect on the level of oral health perception and the number of dental caries. Daily snack intake was the most important effect on DMFT number. Conclusions : The informed consent from each family was the important factor in implementing PRECEDE model. School health program improved oral health care. Oral health program can correct the risk oral health behavior in children and adolescents.

• 셀메드
• /
• 제5권2호
• /
• pp.13.1-13.5
• /
• 2015

Many patients with psoriasis look for treatment options other than conventional treatment to control their disease with less side effects. We evaluated the prevalence and characteristics of herbal therapy usage among patients with psoriasis in Turkey. A self-prepared questionnaire about herbal therapies was applied to the psoriatic patients attended our dermatology clinic between October 2013 and December 2013. A total of 100 patients (55 male, 45 female; 7 - 80 years of age) were included in this study. Fortynine percent of patients used at least one form of herbal therapies. Juniperus oxycedrus and Aloe vera were found to be the most frequently used plants. 36.7% of the patients get benefit from herbal therapy. Only 12.2% of patients had informed their clinicians during or after herbal therapy usage. 22.4% of the patient had continued conventional treatment during herbal therapies. Side effects related with herbal therapy were developed in 26.5% of the patients. The risk of side effects was found to be 5.23 times more in patients using phytotherapies systemically compared with ones using topically. Our results show that herbal therapy usage is common among patients with psoriasis in Turkey. Since herbal therapies have the potential of interacting with the medical treatment modalities and causing life threatening allergic reactions, clinicians should be aware of plants used in psoriasis and possible adverse reactions related with them and also should not forget asking about herbal therapy history.

• Journal of Genetic Medicine
• /
• 제8권2호
• /
• pp.100-104
• /
• 2011

유전자 검사는 생명과학의 발달과 더불어 질병 진단 및 연구의 중요한 수단으로 일반화되고있으나, 태아에 대한 유전자 검사는 자기결정권이 없는 태아를 대상으로 하기 때문에 또 다른 윤리적, 사회적 문제가 있을 수 있으므로 특별한 주의를 기울여야 한다. 따라서 태아 유전자 검사를 시행하기 전에 유전 상담이 충분히 이루어져서 부모에게 병의 진단, 자연경과, 가능한 치료를 이해시키며, 질환의 유전방식과 가족의 재발 위험도를 평가하고 그에 따른 가능한 선택을 제시하여 가족들이 질환에 대해 최선의 결정을 할 수 있게 도움을 주어야 한다. 뿐만 아니라 태아 유전자 검사에 대한 현행법의 합리적인 법률 개정도 뒷받침되어야 한다.

• Nuclear Engineering and Technology
• /
• 제51권1호
• /
• pp.138-145
• /
• 2019

With the application of digital technology to safety-critical infrastructures, cyber-attacks have emerged as one of the new dangerous threats. In safety-critical infrastructures such as a nuclear power plant (NPP), a cyber-attack could have serious consequences by initiating dangerous events or rendering important safety systems unavailable. Since a cyber-attack is conducted intentionally, numerous possible cases should be considered for developing a cyber security system, such as the attack paths, methods, and potential target systems. Therefore, prior to developing a risk-informed cyber security strategy, the importance of cyber-attacks and significant critical digital assets (CDAs) should be analyzed. In this work, an importance analysis method for cyber-attacks on an NPP was proposed using the probabilistic safety assessment (PSA) method. To develop an importance analysis framework for cyber-attacks, possible cyber-attacks were identified with failure modes, and a PSA model for cyber-attacks was developed. For case studies, the quantitative evaluations of cyber-attack scenarios were performed using the proposed method. By using quantitative importance of cyber-attacks and identifying significant CDAs that must be defended against cyber-attacks, it is possible to develop an efficient and reliable defense strategy against cyber-attacks on NPPs.