• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.299-302
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• 2013

Methylenetetrahydrofolate reductase (MTHFR) has been reported to be associated with DNA methylation, an epigenetic feature frequently found in gastric cancer. We conducted a case-control study to explore the association of MTHFR C677T polymorphisms with gastric cancer risk and its relation with the DNA methylation of COX-2, MGMT, and hMLH1 genes. Genotyping of P16, MGMT and HMLH1 was determined by methylation-specific PCR after sodium bisulfate modification of DNA, and genotyping of MTHFR C677T was conducted by TaqMan assays using the ABI Prism 7911HT Sequence Detection System. Folate intake was calculated with the aid of a questionnaire. Compared with the MTHFR 677CC genotype, the TT genotype was significantly associated with 2.08 fold risk of gastric cancer when adjusting for potential risk factors. Individuals who had an intake of folate above $310{\mu}g$/day showed protective effects against gastric cancer risk. The effect of MTHFR C677T polymorphisms on the risk of gastric cancer was modified by folate intake and methylation status of MGMT (P for interaction <0.05).

• The Journal of the Korean dental association
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• v.52 no.8
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• pp.472-477
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• 2014

The new paradigm of dentistry require the detection of caries in their earlier stages. To achieve this, a high technology detection device and systematic and organized caries management system are needed. Caries management by risk assessment (CAMBRA) model is representative caries management system that satisfied new paradigm. Dental caries prevention and treatment according to CAMBRA model is patient-centered, risk-based, evidence-based practice. Therefore, individual caries management such as CAMBRA should be performed through accurate assessment of caries disease indicators and comprehensive assessment of caries risk factors and protective factors. Based on the CAMBRA better effectiveness of comprehensive dental caries management including non-surgical treatment will be accomplished.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.5
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• pp.765-774
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• 2023

The Ministry of Employment and Labor implemented the process safety management(PSM) system from 1996 to prevent major industrial accidents caused by chemical substances, but the number of accidents did not drastically decrease. Even in workplaces with excellent PSM ratings, large-scale chemical accidents still occur due to non-compliance with safety work procedures and insufficient safety measures during maintenance and other work. Accordingly, the chemical accident risk warning system was introduced in 2014 to supplement the PSM system and prevent accidents that may occur during regular or unexpected maintenance and repair work. In the meantime, changes in the safety management system have been checked since the introduction of the chemical accident risk warning system at chemical handling workplaces, and based on the results, a plan for upgrading this system has been proposed. The effect of the CARW system was found to directly prevent accidents through wired and on-site consulting and post-management at the workplace and indirectly contribute to the establishment of a safety and health management system at the workplace, such as improving safety culture awareness.

• Journal of the Korea Society of Computer and Information
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• v.24 no.1
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• pp.101-106
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• 2019

In this paper, we investigate the patient fall prevention system to prevent the patient from falling out of the bed unintentionally on the bed of the bed. Patients stay in bed for many hours of hospitalization. During the hospitalization period, patients have low controllability of the body, as compared with normal persons, and fall due to intentional movements, resulting in a fall of the patient, can be a fatal threat to the patient. Therefore, an efficient fall prevention system is required. In this paper, the distance map to the patient is generated by the distance measuring sensor on the bed of the patient, and the risk is determined by estimating the position of the patient based on the distance map. As a result, when the distance map of the dangerous area is 150 mm or more, it is determined to be dangerous, and good results are obtained.

• Journal of the Korean Society of Safety
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• v.33 no.5
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• pp.141-149
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• 2018

In a PCB factory, there is a corrosive chemical substance supply system that can causes major leakage accidents. These accidents can give rise to shut down the factory and do residents damage that cause enormous loss of properties. To mitigate these risks, it is necessary to provide a chemical disaster prevention system. Moreover, after considering the situation and environment of the production site, it is of great importance to build an optimal chemical accident prevention system by reflecting risk reduction measures from the point of process design and by assessing quantitative risk based on reliability data. However, because there was no established database of the reliability about facilities and equipment that can be used in the domestic, the business site and consulting organization had being used the reliability data such as USA CCPS(Center for Chemical Process Safety). In these days, Korean institutes are studying on reliability data utilization method of quantitative risk assessment for preventing chemical accidents and domestic utilization algorithms and storage bed of reliability data. This study presents samples of reliability database about the chemical substance supply system that constructed from the history data such as failure, maintenance for 10 years at a PCB factory. Also, this work proposes the safety design criteria for supply facilities of corrosive chemical substance by assessing quantitative risk on the basis of the reliability data.

• Journal of Korea Multimedia Society
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• v.23 no.1
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• pp.15-23
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• 2020

Recently, the increase in the elderly population due to an aging society has led to a relative increase in senile diseases such as vascular dementia or Alzheimer's disease, and the social burden for rehabilitation has increased. In addition, studies have been conducted for the risk assessment and prevention of musculoskeletal disorders. The purpose of this study is to suggest a system that can be used to help with dementia prevention training by tracking the movement of motion and virtual reality contents for the risk factors of musculoskeletal disorders of the elderly. We propose a training method for preventing dementia through musculoskeletal motion analysis algorithm and virtual reality content. Through motion recognition algorithm based on motion region design, we will track and analyze the moving radius of the target joint. The purpose of this study is to calculate and evaluate scores based on the time to accomplish the goals on virtual reality contents for the prevention of musculoskeletal disorders and the support of dementia prevention training, and the degree of difficulty, and to analyze the correlation between the results of performing K-MMSE and VR contents.

• Archives of Obesity and Metabolism
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• v.2 no.2
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• pp.37-44
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• 2023

Weight gain is defined as the increase in body weight, increasing the prevalence of obesity, and results in metabolic diseases. Weight gain was reportedly caused by the interaction between the obesogenic environmental factors and individual metabolic factors. Sociodemographic and environmental factors (demographic factors, lifestyle/behavioral factors, food/nutritional factors, socioeconomic factors), drug-related secondary causes (some of the corticosteroids, antihyperglycemics, antihypertensives, antidepressants, etc.), and metabolic factors (aging and hormonal changes, menopause and decreased sex hormones, decreased adipocyte degradation, decreased fibroblast growth factor 21, central sympathetic nervous system hyperactivity, decreased sympathetic-adrenomedullary system activity) are significant factors related to weight gain. It is crucial to prevent weight gain and maintain an ideal weight, but studies on the risk factors of weight gain are insufficient. Therefore, this study evaluated the factors associated with weight gain to find strategies for preventing unnecessary weight gain.

• Journal of Forest and Environmental Science
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• v.40 no.1
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• pp.24-34
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• 2024

Fire, being primarily a natural phenomenon, is impossible to control, although it is feasible to map the forest fire risk zone, minimizing the frequency of fires. The spread of a fire starting in any stand in a forest can be predicted, given the burning conditions. The natural cover of the land and the safety of the population may be threatened by the spread of forest fires; thus, the prevention of fire damage requires early discovery. Satellite data and geographic information system (GIS) can be used effectively to combine different forest-fire-causing factors for mapping the forest fire risk zone. This study mainly focuses on mapping forest fire risk in the Madikhola watershed. The primary causes of forest fires appear to be human negligence, uncontrolled fire in nearby forests and agricultural regions, and fire for pastoral purposes which were used to evaluate and assign risk values to the mapping process. The majority of fires, according to MODIS events, occurred from December to April, with March recording the highest occurrences. The Risk Zonation Map, which was prepared using LULC, Forest Type, Slope, Aspect, Elevation, Road Proximity, and Proximity to Water Bodies, showed that a High Fire Risk Zone comprised 29% of the Total Watershed Area, followed by a Moderate Risk Zone, covering 37% of the total area. The derived map products are helpful to local forest managers to minimize fire risks within the forests and take proper responses when fires break out. This study further recommends including the fuel factor and other fire-contributing factors to derive a higher resolution of the fire risk map.

• Journal of Korean Academy of Nursing Administration
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• v.12 no.3
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• pp.373-384
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• 2006

Purpose: This is a pilot study to identify patient safety risk factors and strategies for patient safety management perceived by nurses. Methods: Data were collected and analyzed with an open questionnaire from April to May 2005, targeted on 100 nurses working in two hospitals. The issues were 'what are risk factors for patients, nurses, and other medical practitioners? How do they prevent with the aftermath of risk factors, causes of incidents?' For data analysis, types and frequency of risk factors were worked out, using the Australian Incident Monitoring System Taxonomy. Results: The types of patient safety risk factor perceived by nurses were as follows ; therapeutic devices or equipment, infrastructure and services (29.5%), nosocomial infections (16.3%), clinical processes or procedures (15.4%), behavior, human performance, violence, aggression, security and safety (12.2%), therapeutic agents (9.7%), injuries and pressure ulcers (8.7%), logistics, organization, documentation, and infrastructure technology (5.6%). Strategies for patient safety included training of prevention of infection, education about safety management for patients and medical professionals, establishment of reporting system, culture of care, pre-elimination of risk factors, cooperative system among employees, and sharing information. Conclusion: These results will be used to provide evidences for patient safety management and educational program.

• Journal of the Korean Society of Safety
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• v.35 no.2
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• pp.84-93
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• 2020

In recent years, the scale of damage from disasters such as earthquakes and large-scale fires and floods that are occurring in Korea is increasing. Accordingly, interest in urban disaster prevention that combines living infrastructure such as roads and parks is boosting, and it is urgent to prepare measures to reduce the damage scale of local cities. The purpose of this study is to derive implications for disaster prevention measures in areas where disaster prevention safety of local cities is weak through examples of disaster prevention safety of local cities in case of disaster. To this end, this study analyzed the regional characteristics, current status, and disaster prevention problems of regional cities in Japan, and selected disaster-vulnerable areas, and considered the distance relationship between disaster prevention bases through road network analysis. In addition, road closure simulation using ArcGIS Network Analyst was conducted to analyze disaster prevention safety in the area. As a result, the situation of the village which has a high possibility of isolation by natural disasters was grasped in advance. Through this, the suburbs confirmed the necessity of supplementing the disaster prevention function through transportation maintenance such as forest roads, and it was found that the city needs to prepare a risk management system. Furthermore, this study suggests the need for research on areas with a high possibility of isolation, especially in areas where disaster prevention functions are weak in local cities in case of disaster, and shows countermeasures for disaster prevention measures and resident education.