• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.5
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• pp.960-967
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• 2009

Power supply system of electric railway has a diversity of safety problems since it should supply high electric power to the trains moving high speed with a lot of passengers on board. This paper provides a risk assessment approach to safety management of the electric railway facilities. Construction of database from field accident information, risk assessment and management of the risk are carried out systematically to ensure the safety. The risk assessment includes hazard identification, cause analysis by FTA(Fault Tree Analysis), consequence analysis by EVA(Event Tree Analysis), and loss analysis. In terms of the severity and the probability of the accidents deduced by these analyses, the risk of the accidents is assessed by using a risk matrix designed for electric railway facilities. Based on the risk assessment, possible risk mitigation options are identified and evaluated by analyzing their impact on the risk reduction and their cost benefit ratio. The long-term safety of the electric railway facilities can be ensured by renewal of the risk assessment and the risk mitigation option analysis with continuous accident database update. The proposed approach is applied to the electric railway facilities of Korean railway based on the accident data from 2002 to 2008.

• Journal of Korean Society on Water Environment
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• v.25 no.4
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• pp.494-501
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• 2009

Probabilistic Ecological risk assessment (PERA) is extensive approach to qualify and quantify risk on the multi species based on species sensitivity distribution (SSD). As a while, deterministic ecological risk assessment (DERA) considers the comparison of predicted no-effect concentration (PNEC) and predicted exposure concentration (PEC). DERA is used to determine if there is potential risk or no risk, and it doesn't consider the nature variability and the species sensitivity. But PERA can be more realistic and reasonable approach to estimate likelihood or risk. In this study, we compared PERA used in developed countries, and proposed PERA applicable for the Korean water environment. Taxonomic groups were classified as "class" level including Actinopterygill, Branchiopoda, Chlorophyceae, Maxillapoda, Insects, Bivalvia, Gastropoda, Secernentea, Polychaeta, Monocotyldoneae, and Chanophyceae in this study. Statistical extrapolation method (SEM), statistical extrapolation method $_{acutechronicratio}$ ($SEM_{ACR}$) and assessment factor method (AFM) were used to calculate the ecological protective concentration based on qualitative and quantitative levels of taxonomic toxicity data. This study would be useful to establish the PERA for the protection of aquatic ecosystem in Korea.

• Molecular & Cellular Toxicology
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• v.4 no.3
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• pp.260-266
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• 2008

Recently, there has been scientific discussion on the utility of -omics techniques such as genomics, proteomics, and metabolomics within toxicological research and mechanism-based risk assessment. Toxicogenomics is a novel approach integrating the expression analysis of genes (genomic) or proteins (proteomic) with traditional toxicological methods. Since 1999, the toxicogenomic approach has been extensively applied for regulatory purposes in order to understand the potential toxic mechanisms that result from chemical compound exposures. Therefore, this article's purpose was to consider the utility of toxicogenomic profiles for improved risk assessment, explore the current limitations in applying toxicogenomics to regulation, and finally, to rationalize possible avenues to resolve some of the major challenges. Based on many recent works, the significant impact toxicogenomic techniques would have on human health risk assessment is better identification of toxicity pathways or mode-of-actions (MOAs). In addition, the application of toxicogenomics in risk assessment and regulation has proven to be cost effective in terms of screening unknown toxicants prior to more extensive and costly experimental evaluation. However, to maximize the utility of these techniques in regulation, researchers and regulators must resolve many parallel challenges with regard to data collection, integration, and interpretation. Furthermore, standard guidance has to be prepared for researchers and assessors on the scientifically appropriate use of toxicogenomic profiles in risk assessment. The National Institute of Toxicological Research (NITR) looks forward to an ongoing role as leader in addressing the challenges associated with the scientifically sound use of toxicogenomics data in risk assessment.

• Journal of the Korean Chemical Society
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• v.67 no.1
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• pp.19-27
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• 2023

During the past few decades, toxicity science is shifting from observative to predictive science. New approach methodologies (NAMs), including in chemico, in silico, in vitro approach, gain attention to reduce, refine, replace the whole animal toxicity testing. However, actual acceptances of NAMs in regulatory decision-making have been limited due to low confidence. To address the current constraints, Accelerating the Pace of Chemical Risk Assessment (APCRA) initiative conducted several case studies and presented the perspectives of next generation risk assessment (NGRA). In this review, we suggested a concept and perspectives of NGRA through analysis on APCRA case studies.

• Journal of the Korean Society of Systems Engineering
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• v.11 no.1
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• pp.9-24
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• 2015

Construction industry faces a lot of inherent uncertainties and issues and the construction phase of nuclear power project is not free from this risk. This paper investigates promising methodologies to be used on nuclear power plant (NPP) construction schedule delay risk assessment by using entry level systems engineering approach. This study contains how the initial concept for the risk assessment methodology has been developed. In this point of view, this work structured on three main phases: needs analysis (NA), concept exploration (CE), and concept definition (CD) through systems engineering (SE) approach. Traditionally, the SE process is applied to technical development programs but this study opens up a new avenue that SE can also be successfully applied to the development and optimization of the risk assessment model. This study provides a rational and systematic process for developing and selecting the best risk assessment model. This paper selects analytic hierarchy process (AHP) method to assess NPP construction schedule delay risk for international project. As conclusion, the proposed concept and selected method can discriminate successfully and clearly among schedule delay risk assessment methods.

• 대한예방의학회:학술대회논문집
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• 1994.02a
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• pp.402-403
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• 1994

There are three different approaches to chemical risk assessment which will be considered in this paper. The U.S. Environmental Protection Agency(EPA) Cancer Risk Assessment includes some of the approaches used by the International Agency for Research on Cancer (IARC). The Agency for Toxic Substances and Disease Registry (ATSDR) effort is an evaluated database approach similar to that used in the National Institute for Occupational Safety and Health (NIOSH) Criteria Documents and in the documentations prepared by the Occupational Safety and Health Administration (OSHA) for the Permissible Exposure Limits (PELs) and those of the American Conference of Governmental Industrial Hygienists (ACGIH) for the Threshold Limit Values (TLVs). A third approach is used by the Committee on Toxicology.

• Korean Journal of Construction Engineering and Management
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• v.8 no.4
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• pp.99-109
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• 2007

Risk elements of highway safety facilities are affected by complex environments. Thus, risk-based approach for traffic safety facilities is needed. For this, in this study, qualitative and quantitative risk assessment methodology and procedure for highway safety facilities is proposed, which can be used as risk-based approach incorporating VE process. Also, for the quantitative risk assessment, event tree using EPDO(Equivalent Property Damage Only) with respect to frequency and magnitude of risk events is introduced. As a result, risk index of alternative 1(140cm) and 2(127(cm) which can be used as performance factor in VE approach are estimated.

• Journal of Navigation and Port Research
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• v.40 no.5
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• pp.257-263
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• 2016

Mombasa is the principle port of Kenya, serving inland countries in Eastern and central Africa. Mombasa port has undergone a massive infrastructure upgrade and dredging works with an expectation that more vessels and large post Panamax ships will be able to enter Mombasa port. Therefore, it is vital to carry out a marine traffic risk assessment in order to quantify the degree of navigation safety needed in the Mombasa approach channel and also to evaluate the navigation risk imposed on transit traffic by local ferry traffic. In this paper, a marine traffic risk assessment is carried out using the IWRAP mk2, Environmental Stress (ES) model, and the PARK model. Risk assessment results show that Likoni area has an unacceptable stress/risk ranking at 20.7% by the ES model and 38.89% by the PARK model. The IWRAP mk2 model shows that the crossing area has the highest risk of crossing collision and the area at the entrance to the inner channel has a high risk of grounding. The conclusions derived from this study will provide the basis for proposing the most effective countermeasure to improve navigation safety in the Mombasa approach channel.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.81-84
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• 2016

Mombasa is the principle port of Kenya, serving hinter countries in Eastern and central Africa. Mombasa port has undergone a massive infrastructure upgrade and dredging works with an expectation that more vessels and large post Panamax ships will be able to call at Mombasa port. Therefore, it is vital to carry out a marine traffic risk assessment so as to quantify the degree of navigation safety on Mombasa approach channel and also to evaluate navigation risk imposed on transit traffic by local ferry traffic. In this paper marine traffic risk assessment is carried out using IWRAP mk2, Environmental Stress model, and PARK model. Risk assessment results show that Likoni area has unacceptable stress/ risk ranking at 20.7% on ES model and 38.89% by PARK model. IWRAP mk2 model shows that crossing area has the highest risk of crossing collision and the area at the entrance to inner channel has a high risk of grounding. The conclusions derived from this study will provide the basis for proposing the most effective countermeasure so as to improve navigation safety in Mombasa approach channel.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.4B
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• pp.261-266
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• 2012

In this study, soil environmental impact assessment using risk-based approach was compared with that using concentration-based approach. For this, heavy metal contaminant exposure was characterized in an abandoned mine area. According to the estimated carcinogenic and non-carcinogenic risks, soil ingestion was identified as the most dominant exposure pathway. When contaminant concentrations exceeded the Korean Soil Contamination Warning Standards, their corresponding risk values also exceeded the Total Soil Risk Standard. Even the cases of satisfying the Korean Soil Contamination Warning Standards mostly showed higher risk levels than the Total Soil Risk Standard, re-confirming a more sensitivity of the risk-based assessment than concentration-based assessment. However, the in-depth analysis of the estimated non-carcinogenic risk values revealed a few cases for soil contact pathway showing contaminant concentrations higher than the Korean Soil Contamination Warning Standards although their non-carcinogenic risk values satisfied the level of Hazard Index Standard. The findings from this study support a necessity of shifting policy paradigm from concentration-based approach into risk-based approach for reliable risk assessment in abandoned mine areas, and also suggest a necessity of further fundamental studies regarding risk factors and standards.