• Journal of Trauma and Injury
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• 제33권1호
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• pp.48-52
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• 2020

Composite skull defects in patients with severe head injuries are very challenging to manage. The dilemma when deciding whether to perform a definitive reconstruction is how long to wait for physiological recovery before an intervention complicates the situation. The inability of such patients to tolerate prolonged anesthetic exposure is a driving factor for performing the minimal intervention necessary to facilitate recovery. Herein, we present a case involving the successful immediate reconstructive treatment of a severely head-injured adolescent with a composite scalp defect secondary to trauma. A 14-year-old boy sustained a severe head injury from a motor vehicle accident with a composite scalp defect in the right fronto-parietal region. The frontal lobe was exposed, and the right eye was crushed and devitalized. The patient was deeply unconscious for 3 days, without any significant improvements before reconstructive surgery was proposed due to fear of possible meningitis resulting from the exposure of brain structures. We successfully managed the patient with a fronto-parieto-occipital flap, after which the patient promptly recovered consciousness.

• Journal of Chest Surgery
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• 제25권9호
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• pp.955-961
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• 1992

In this study, 237 cases of spontaneous pneumothorax experienced at the department of Thoracic and Cardiovascular Surgery, Kosin Medical College during from January 1986 to December 1990 were analysed retrospectively. 1. The ratio of male to female was 4.6: 1, predominent in male. The incidence of age group was highest as 36% between 21 and 40 years old. 2. The associated diseases of pneumothorax were 27 cases, in which pyothorax were 8 cases, and hydrothorax were 19 cases. 3. The site of pneumothorax was as follows: right side was 53%, left side was 45%, and both side was 2%, so right side was slight high. 4. The empolyed managements were as follows: bed rest with oxygen inhalation in 13 cases, closed thoracostomy in 155 cases, open thoracotomy in 69 cases. 5. The operative procedures of thoracotomy were as follows; simple pleurodesis in 2 cases, blebectomy & bullectomy in 38 cases, parietal pleurecttnny in 4 cases, segmentectomy in 12 cases, lobectomy in 9 cases. 6. The indication of open thoracotomy were as follows, recurrent history in 35 cases, contralateral pneumothorax history in 2 cases, continuous air leakage in 24 cases, bilateral pneumothorax in 2 cases, and visible blebs & bullaes on the chest X-ray in 6 cases. 7. The hospital duration after management was as follow, open thoracotomy in 13.2 days, closed thoracostomy in 22.4 days. The recurrent pneumothorax after closed thoracostomy was 25 cases, about 15%.

• Archives of Plastic Surgery
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• 제32권3호
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• pp.319-326
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• 2005

This study was designed to investigate the optimal period of pedicles implantation in the prefabricated periosteofascial flap using a vascular tissue transfer. Flap prefabrication was prepared with a transposition of the central pedicles of right auricle on the calvarium of the New Zealand white rabbit. Thirty flaps were divided into five groups of six flaps, including control group (group I) of the conventional periosteofascial flap based on the right lateral border of parietal bone. The prefabricated flap was elevated as a $2{\times}2cm$ sized island flap and reposed in place in 1, 2, 3, and 4 weeks after the pedicles transfer in groups II, III, IV, and V, respectively. Five days after flap repositioning, the flap viability and vascularity were evaluated with microangiography and histological study quantitatively. The flap survival was increased in accordance with the implanted period of the pedicle. New vessels developed around the implanted pedicle in the 2nd week, and overall vascularization of the flap was accomplished in the 3rd week. The flap with 4 weeks of implantation period, however, showed the same survival rate as the control group. In conclusion, prefabricated periosteo- fascial flap can be created with a vascular tissue transfer, and the optimal duration of the pedicle implantation is more than 4 weeks to obtain adequate flap survival.

• Journal of Korean Neurosurgical Society
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• 제51권1호
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• pp.47-50
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• 2012

We report here one case of rapid and aggressive course of cerebral metastatic angiosarcoma from the heart. A 36-year-old man presented with 10-days history of headache. Magnetic resonance imaging demonstrated subacute hemorrhage with a small region of enhancement in right parietal region and the pathological diagnosis was angiosarcoma. Transthoracic echocardiography demonstrated $3.2{\times}3$ cm sized mass on right atrial wall. Newly developed lesion was reoperated, three and four weeks later respectively, and whole brain radiotherapy of total 30 Gy was done. With the interval of two months, gamma knife surgery was done for new lesions two times, which were well controlled. Newly developed lesions rapidly happened even in the adjuvant treatment. He died 9 months after the diagnosis because of the aggravation of primary cancer. The cerebral metastatic angiosarcoma from the heart showed the rapid aggressive behavior and the closed follow-up could be needed for the adjuvant treatment.

• 대한두개안면성형외과학회지
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• 제24권1호
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• pp.32-36
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• 2023

The superficial temporal artery (STA), the terminal branch of the external carotid artery, is divided into the frontal (anterior) and parietal (posterior) branches. The frontal branch of the STA is located superficially on the anterior region of the scalp, making it especially susceptible to trauma. Here, we report a traumatic pseudoaneurysm of the STA in a 7-year-old boy who was injured in a minor car accident. A physical examination showed only a small bruise on the patient's forehead, and all vital signs were stable at the emergency room of our medical center. A facial computed tomography scan showed no significant findings. However, the boy later re-visited the hospital with slight swelling on the right forehead, and an ultrasonography scan revealed a hematoma near the right temporal artery. The resected hematoma (approximately 2 cm) was diagnosed as a traumatic pseudoaneurysm. Awareness of the possibility of a traumatic pseudoaneurysm in the STA may prevent a circumspect diagnosis in the future.

• 대한방사선기술학회지:방사선기술과학
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• 제34권1호
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• pp.17-25
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• 2011

본 연구는 만성적인 망간(Mn) 노출 결과로써 초래될 수 있는 영향을 기능적 신경영상기법의 하나인 fMRI(functional magnetic resonance imaging)를 이용하여 인지 활동에 따른 뇌 활성화 정도를 분석, 평가하고자 하였다. 조선소에서 10년 이상 용접 작업을 해왔고 현재도 용접 전담 업무를 하고 있는 34세 이상의 남성 15명을 노출군으로 하였고, 노출군과 연령, 사회·경제적 지위와 행동 패턴이 비슷하며 다른 위험한 금속성 물질에 노출되지 않은 제조업 사업장에서 용접 작업을 하지 않는 생산직 근로자 15명을 대조군으로 구성하여 설문조사와 혈액 검사, fMRI를 실시하였다. 그 결과 fMRI 대상자(29명)의 평균 혈중 Mn 농도는 노출군($1.3\;{\mu}g/dl$)이 대조군($0.8\;{\mu}g/dl$)보다 유의하게 증가하였고, Pallidal Index(PI)도 노출군이 대조군보다 유의하게 증가하였다(p < 0.001). MRI 상의 PI값은 혈중 Mn 농도가 $0.93\;{\mu}g/dl$ 이상인 군이 $0.93\;{\mu}g/dl$ 미만인 군보다 유의하게 증가하였다(p < 0.001). 산술 과제를 수행하는 동안 실험군의 각 문항에 대한 평균 응답 시간은 노출군(1.3 sec)이 대조군(1.1 sec)보다 유의하게 증가하였다. 또한, 문항 전체에 대한 평균 응답 시간도 대조군(54.7 sec)이 노출군(45.0 sec)보다 느리게 나타났으며, 통계학적으로도 유의미한 차이를 보였다(p < 0.001). 대조군의 뇌 활성화 영역은 후두피질의 좌 우측, 상 중간전두피질과 하두정피질(inferior parietal cortex)의 우측, 중간측두피질의 좌측 영역에서 유의하게 증가하였다. 노출군의 뇌 활성화 영역은 대조군의 활성화 영역과 비슷한 위치에서는 보다 넓고 높은 활성화 상태를 보였다. 노출군은 대조군의 활성화 영역에 추가하여 상 하 측두피질의 우측, 뇌섬엽의 좌측, 뇌교량과 측뇌실 영역에서 유의한 증가로 나타났다. 두 집단간 뇌 활성화 영역 비교를 위한 t-test에서 노출군은 중간측두피질 영역을 포함하여 우측 하측두피질, 좌측 상두정피질, 좌측 후두피질, 좌측 소뇌 등의 영역에서 대조군보다 유의하게 더 높은 증가를 나타냈다. 하지만 어떤 영역도 노출군보다 대조군에서 더 활성화된 영역은 없었다. 이상의 결과에서 만성적인 Mn 노출은 인지 과제 수행 중에 뇌 활성화를 증가시켰다. 동일한 과제에서도 상 하 측두피질, 뇌도 영역에서 활성화가 증가되었고, 노출군이 일반인보다 측두영역 및 후두영역에서 뇌 활성화 상태가 증가되었음을 알아냈다. 이상의 결과에서 살펴 볼 때 작업환경 내에서의 만성적인 Mn 노출이 뇌 활성화의 신경 네트워크에 영향을 미친다는 것이 확인되었다.

• 인지과학
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• 제21권1호
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• pp.77-93
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• 2010

본 연구는 마음이론 능력 측정 과제의 하나인 헛디딤 탐지를 수행하는데 관여하는 신경상관 영역을 확인하려는 것이었다. 기능적 자기공명영상 기법을 이용하여 헛디딤 이야기 문장과 헛디딤을 포함하지 않는 통제 이야기 문장을 제시하였을 때 나타나는 뇌 활성화 영역을 비교하였다. 양 반구의 상전두회(BA 6/9)와 설전소엽(BA 7), 좌반구의 내전두회(BA 9), 상측두회(BA 38), 하측두회(BA 20)와 우반구의 하두정소엽(BA 40), 중심후회(BA 1), 설회(BA 18), 횡전두회(BA 41) 등의 영역에서 활성화가 나타났다. 헛디딤 탐지를 하는 동안 안와전두피질과 편도의 활성화는 나타나지 않았다. 이런 결과는 마음이론과 관련된 뇌 활성화는 과제가 이끌어내는 마음상태의 유형에 달려있음을 시사한다.

• Clinical and Experimental Pediatrics
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• 제58권9호
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• pp.354-357
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• 2015

Parry-Romberg syndrome (PRS) is a rare, acquired disorder characterized by progressive unilateral facial atrophy of the skin, soft tissue, muscles, and underlying bony structures that may be preceded by cutaneous induration. It is sometimes accompanied by ipsilateral brain lesions and neurological symptoms. Here we present the case of a 10-year-old girl with right-sided PRS and recurrent monoplegic ataxia of the left leg. At 4 years of age, she presented with localized scleroderma over the right parietal region of her scalp; her face gradually became asymmetric as her right cheek atrophied. Brain magnetic resonance imaging revealed hemiatrophy of the face and skull base, and T2-weighted images showed increased signal in the right hemipons and hemicerebellar peduncle. Magnetic resonance angiography findings were unremarkable. She was treated with oral prednisolone, and her recurrent gait ataxia diminished within 2 months of the follow-up period. To the best of our knowledge, this is only the second case of PRS presenting with an abnormal involvement of the ipsilateral hemipons.

• Journal of Chest Surgery
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• 제37권12호
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• pp.1029-1031
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• 2004

림프관평활근종증은 드문 질환이며, 임상경과상 악성으로 분류할 수 있다. 복통을 주소로 입원한 21세 여자 환자가 골반 내시경을 통해 난소 황체 출혈을 지혈하였고, 그 후 유미성 복수로 개복하여 후 복막에 위치한 낭성 종양을 절제하여 림프관평활근종증으로 조직 진단 받았다. 홀몬 치료 중 유미흉이 발생하여 흉부외과에서 개흉하여 림프액 누출부위를 봉합결찰하였고, 10% 포타딘 관주로 유미흉은 호전되었으나 유미성 복수가 재발하였으며 진단 6개월에 전신 쇠약과 호흡 부전으로 사망하였다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2003년도 춘계학술대회 논문집
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• pp.107-110
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• 2003

본 연구에서는 EEG를 이용하여 정신집중 시, 뇌 기능의 변화를 알아보았다. 실험은 건강한 남녀 고교생 9명을 대상으로 EEG는 Fp1. Fp2, F3, F4, P3, P4, T5, T6, O1, O2의 10위치에 대하여 정신집중 작업 진의 3분과 작업 시 30분간을 측정하였다. 작업은 PC를 이용하였으며 모니터 상의 움직임에 집중하고 목표자극을 탐지하였을 때 신속하게 적절한 반응키를 누르도록 하였다. 각 주파수 대역은 theta2와 (6.0-8.0Hz), alpha1파 (8.0-10.0Hz), alpha2파(10.0-12.0Hz)로 구분하였으며 비대칭지수를 이용하여 분석하였다. 그 결과, 정신집중 작업 시 theta1, theta2, alpha1대역에서 두정엽의 우반구과 측두엽 및 후두엽의 좌반구영역이 우세하였다. 이들 영역은 시갈, 지각, 움직임 기능을 수행하며 theta2파가 주의, alpha1파가 각성 관련이다. 이상의 결과에서 두정엽의 우반구와 측두엽 및 후두엽의 좌반구영역의 theta1파, theta2파, alpha1파가 정신집중 작업 시 중요한 역할을 담당하는 것으로 나타났다.