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Effects of Taegeuk Acupuncture on the Autonomic Nervous System by Analyzing Heart Rate Variability in 20's Soeumin (태극침법이 정신적 스트레스를 가한 20대 소음인 남성의 심박변이도에 미치는 영향)

  • Kim, Nam Sik;Kim, Jin Youp;Kwak, Sang Gyu;Shin, Im Hee;Nam, Sang Soo;Kim, Yong Suk
    • Journal of Acupuncture Research
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    • v.30 no.3
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    • pp.39-49
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    • 2013
  • Objectives : The purpose of this study is to assess the effect of Taegeuk acupuncture on reducing mental stress by analyzing heart rate variability in Soeumin. Methods : Six Soeumin-diagnosed men participated in this study. They were randomly divided into group A and group B. Each participant went through 4 sessions every week with 1 week of washout period in between each session. HRV was measured three times at every session; at baseline, after administering mentally stressful circumstances and after applying Soeumin Taegeuk acupuncture or Soyangin Taegeuk acupuncture. This study was designed as a crossover clinical trial. Group A participants were treated with two sets of Soeumin Taegeuk and Soyangin Taegeuk acupuncture treatment in respective order (i.e. Soeumin Taegeuk - Soyangin Taegeuk - Soeumin Taegeuk - Soyangin Taegeuk acupuncture treatment). Group B participants were treated with reverse-ordered acupuncture treatment (i.e. Soyangin Taegeuk - Soeumin Taegeuk - Soyangin Taegeuk - Soeumin Taegeuk acupuncture treatment ). Bayesian analysis was performed by using WinBUGS(Ver. 1.4.3) for comparison between Soeumin Taegeuk acupuncture and Soyangin Taegeuk acupuncture. Results : Overall, Soeumin Taegeuk acupuncture tends to reduce LF/HF ratio, LF, HF, LF(Norm) and increase HF(Norm) more than Soyangin Taegeuk acupuncture, but the difference was not statistically significant. In one participant, however, Soeumin Taegeuk acupuncture reduced LF/HF ratio, LF(Norm) and increased HF(Norm) more than Soyangin Taegeuk acupuncture, and the difference was stastatistically significant. Conclusions : This study suggests that Soeumin Taegeuk acupuncture might be an effective means of stabilizing mental stress-induced imbalance of autonomic nervous system for Soeumin.

Investigation of 'First-Night Effect' in Normal Young Adult Male Subjects on Polysomnography (젊은 정상인 남자에서 수면다원기록상의 '첫날밤 효과' 분석)

  • Kim, Eui-Joong;Jeong, Do-Un
    • Sleep Medicine and Psychophysiology
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    • v.5 no.1
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    • pp.111-117
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    • 1998
  • Objectives : 'First-night effect' has been a well-known concept since 1960's. It is important because it is one of the major factors to be considered in assessing the reliability of polysomnographic data. However, 'reverse first-night effect' has also been described, resulting in the inconsistency of conceptualization. We attempted to investigate on the first-night effect in adults by having each of them take two nights of polysomnography in a controlled environment. Young healthy adult volunteers were chosen as subjects in order to rule out age- or health-related confounders. Methods : Polysomnography was performed on eight male medical students (mean $age=23.5\;{\pm}\;0.9$) for two nights with Grass model 78 polysomnograph. We scored manually under the standard protocol each epoch of the sleep records. Sleep variables were obtained and compared between the two nights. Results : Sleep period time(SPT) and total sleep time(TST) of the third fraction of night were significantly longer on the first night than on the second night (p<0.05). However, other sleep variables such as percentage of each sleep stage, sleep latency, REM sleep latency, number of waking, and sleep efficiency were not different between the two nights. Conclusion : We could not confirm the existence of first-night effect in this study. In healthy young male adults, it may not happen at all or may happen to a very negligible degree. Young healthy adults may have more adaptability to a new sleep environment. Also, the provision of a reasonably comfortable sleep environment could have helped them with abolition of first-night effect.

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Effects of $H_2O_2$ and ascorbic acid on TIMP-2, Type1 collagen, and PDLs22 levels in human periodontal ligament fibroblasts (($H_2O_2$와 ascorbic acid가 사람 치주인대섬유모세포의 TIMP-2, Type 1 collagen, PDLs22 발현에 끼치는 효과)

  • Choi, Yong-Sun;Kim, So-Young;Choi, Seong-Mi;Jang, Hyun-Seon;Kim, Byung-Ock
    • Journal of Periodontal and Implant Science
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    • v.37 no.4
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    • pp.655-669
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    • 2007
  • Reactive oxygen species (ROS) have been implicated in the pathogenesis of various diseases. And vitamin C has shown a protective effect for the tissues. The aim of this study was to evaluate the effects of $H_2O_2$ and ascorbic acid on matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase (TIMP: TIMP-1, TIMP-2), Type 1 collagen, fibronectin, and PDLs22 level in human periodontal ligament fibroblasts (hPDLF) via reverse transcription-polymerase chain reaction (RT-PCR). hPDLF was obtained from a healthy periodontium and cultured in Dulbecco's modified Eagles's medium plus 10% fetal bone serum. The concentration of ascorbic acid in hPDLF was $50{\mu}g/ml$, and that of $H_2O_2$ in hPDLF was 0.03% and 0.00003%. Ascorbic acid only, $H_2O_2$ only and mixture of ascorbic acid and $H_2O_2$ were applied with hPDLF for 1-, 3-, and 30-min. respectively. The gene expression of MMP-1-, TIMP-1-, TIMP-2-, Type 1 collagen-, fibronectin-, and PDLs22-mRNA in hPDLF was analysed via RT-PCR. The results were as follows; 1. hPDLF in response to 30-min. incubation with 0.03% $H_2O_2$ did not show any gene expression. 2. In all the experimental groups, the gene expression of fibronectin mRNA showed the decreased tendency compared to control. 3. In all the experimental groups, the gene expression of TIMP-1 mRNA showed the tendency similar to control. 4. hPDLF in response to 30-min. incubation with 0.03% $H_2O_2$ and ascorbic acid increased mRNA induction for MMP-1. 5. In all the experimental groups, hPDLF increased mRNA induction for PDLs22, collagen type 1, and TIMP-2 compared to control. Within the limited experiments, $H_2O_2$ and ascorbic acid increased mRNA induction for PDLs22, collagen type 1, TIMP-2 in hPDLF. More research will be needed in order to confirm the relative importance of the different roles of ROS and antioxidants in hPDLF from a periodontal regeneration or repair standpoint.

THE STUDY ON SHEAR BOND STRENGTHS OF VARIOUS ONE-BOTTLE DENTIN ADHESIVES (수종의 One-bottle 상아질 결합제의 전단 결합 강도에 관한 연구)

  • Oh, So-Hee;Kim, Jong-Soo;Kwon, Soon-Won
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.4
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    • pp.553-565
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    • 2001
  • One-bottle adhesive system was recently developed in order to simplify the clinical skills and save chair time after continuous improvements on dentin bonding agents. To test the shear bond strength of a new "one-bottle adhesive" system to bovine dentin various commercially available one-bottle adhesives(Prime & Bond $2.1^{(R)}$, One Coat $Bond^{(R)}$, Syntac $Sprint^{(R)}$, Single $Bond^{(R)}$) were included for comparison. And we observe the interfacial morphology by scanning electron microscope. The results were as follows; 1. Group II (One Coat $Bond^{(R)}$) showed higher shear bond strength than group I (Prime & Bond $2.1^{(R)}$), group III(Syntac $Sprint^{(R)}$), and group IV(Single $Bond^{(R)}$), but no statistically significant difference was founded between groups(p>.05). 2. Relating reverse-cone shape resin tags were observed in samples of all groups under SEM. We could observed hybrid layer, resin tag and many lateral branches in every group. But, we observed in group III rare lateral branched than other three groups, and discontinuous hybrid layer.

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Theoretical Studies of the Gas-Phase Identity Nucleophilic Substitution Reactions of Cyclopentadienyl Halides

  • Lee, Ik-Choon;Li, Hong-Guang;Kim, Chang-Kon;Lee, Bon-Su;Kim, Chan-Kyung;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
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    • v.24 no.5
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    • pp.583-592
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    • 2003
  • The gas phase identity nucleophilic substitution reactions of halide anions (X = F, Cl, Br) with cyclopentadienyl halides (1) are investigated at the B3LYP/6-311+G**, MP2/6-311+G** and G2(+)MP2 levels involving five reaction pathways: σ-attack $S_N2$, β-$S_N$2'-syn, β-$S_N$2'-anti, γ-$S_N$2'-syn and γ-$S_N$2'-anti paths. In addition, the halide exchange reactions at the saturated analogue, cyclopentyl halides (2), and the monohapto circumambulatory halide rearrangements in 1 are also studied at the same three levels of theory. In the σ-attack $S_N2$ transition state for 1 weak positive charge develops in the ring with X = F while negative charge develops with X = Cl and Br leading to a higher energy barrier with X = F but to lower energy barriers with X = Cl and Br than for the corresponding reactions of 2. The π-attack β-$S_N$2' transition states are stabilized by the strong $n_C-{\pi}^{*}_{C=C}$ charge transfer interactions, whereas the π-attack γ-$S_N$2' transition states are stabilized by the strong $n_C-{\sigma}^{*}_{C-X}$ interactions. For all types of reaction paths, the energy barriers are lower with X = F than Cl and Br due to the greater bond energy gain in the partial C-X bond formation with X = F. The β-$S_N$2' paths are favored over the γ-$S_N$2' paths only with X = F and the reverse holds with X = Cl and Br. The σ-attack $S_N2$ reaction provides the lowest energy barrier with X = Cl and Br, but that with X = F is the highest energy barrier path. Activation energies for the circumambulatory rearrangement processes are much higher (by more than 18 kcal $mol^{-1}$) than those for the corresponding $S_N2$ reaction path. Overall the gas-phase halide exchanges are predicted to proceed by the σ-attack $S_N2$ path with X = Cl and Br but by the β-$S_N$2'-anti path with X = F. The barriers to the gas-phase halide exchanges increase in the order X = F < Br < Cl, which is the same as that found for the gas-phase identity methyl transfer reactions.

A Study on The Principles and Philosophical Basis of 'Sa Sang Medicine' (사상의학(四象醫學)의 원리(原理)와 철학적(哲學的) 배경(背景)에 대(對)한 고찰(考察))

  • Song, Jeong-Mo
    • Journal of Sasang Constitutional Medicine
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    • v.4 no.1
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    • pp.5-29
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    • 1992
  • In this study, the author researched the process in which the philosophical basis of 'Sa Sang Medicine (四象醫學)' and its methodology build up the principles of Sa Sang Medicine, and then, examined how the principles were applied to the theoretical system of Sa Sang Medicine. The conclusion would be summarized as follows. 1. 'Nae Kyung Medicine (內經醫學)' was developed under the concept that the cosmos's order and its moving rule could be directly applied to that of human body, which corresponded to the 'Theory of Hwang-No (黃老之學)'. On the contrary, Sa Sang Medicine is a thoroughly human-oriented theory formed in the Confucianism system. 2. Lee Jae-Ma's Substantialism can be briefed into 'Mind 心' (Tae Keuk 太極), 'Mind-Body 心身' (Yang Eui 兩儀) and 'Activity-Mind-Body-Matter 事心身物' (Sa Sang 四象), which respectively represents one-elemented substance, two-elemented substance and four-elemented substance. Especially, Sa Sang was used as a basic framework in which he recognized all the objects and phenomena. So, most critical significance of his substantialism consists in the intention of Sa Sang type classifying. 3. By the method of Sa Sang type classifying, Lee Jae-Ma not only redefined the main concepts of confucianism and developed a unique philosophy of his own, but also, in the field of medical science, resystemized and re-explained the structure and function of human body. 4. From the recognition that Activity-Mind-body-Matter (Sa Sang) are four different existence forms of energy 氣 (or four variation types of energy), Yi Jae-Ma thinks that the viscera of human body have a vertical structure of 'four parts 四焦' (upper, mid-upper, mid-lower and lower parts) and its physiological function is operated by the rising and falling action of four energy presentations (sorrow 哀, anger 怒, joy 喜 and pleasure 樂). 5. In "Gyuk Chi Go 格致藁", Lee Jae-Ma understood the concept of joy, anger, sorrow and pleasure on the basis of nature-emotion theory 性情論 from the philosophical viewpoint. But, from the medical viewpoint of "Dong Eui Su Se Bo Won 東醫壽世保元", he understood them on the basis of vital energy theory. That is, sorrow, anger, joy and pleasure are expression of advance or reverse of nature vital-energy 性氣 and emotion vital-energy 情氣. 6. The rising and falling action principle of four energy presentations (sorrow, anger, joy and pleasure) which produces and helps each other is an identical principles of Sa Sang Medicine, distinguished from the Oh-Haeng 五行 circulating principle in Nae Kyung Medicine. Through this principle, Lee Jae-Ma explained the viscera physiology of human body, pathology & diagnosis and pharmacology.

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Structure and Dynamics of Taxus cuspidata Populations (주목(Taxus cuspidata) 개체군의 구조와 동태)

  • Chun, Young-Moon;Hong, Moon-Pyo;Lee, Na-Yeon;Seo, Eun-Kyoung;Lee, Seung-Ho
    • Korean Journal of Plant Resources
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    • v.25 no.1
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    • pp.123-131
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    • 2012
  • This study analyzed on the characteristics of community structure, species composition, population conditions and annual mean radial growth of Taxus cuspidata in the subalpine zone of the Seoraksan, Deokyusan, and Hallasan National Parks. Deokyusan and Hallasan sites had three layers of stratification structure without tree layer in it and four layer in Seoraksan site. The major dominant species in the order of importance value were as follows: T. cuspidata, Acer tschonoskii var. rubripes, Quercus mongolica, Abies koreana and Sorbus commixta. The trees (> 5 cm DBH) of T. cuspidata were extremely high with 986.0 individuals/ha at the Hallasan site. Average DBH class were 42.0 cm at the Hallasan site and mainly showed large class. The populations of seedlings and saplings with 357.3 individuals/ha, and juvenile with 128.6 individuals/ha, as a succession tree, were found to be the highest at the Hallasan site. In the size frequency distribution, the populations of T. cuspidata in Mt. Halla site showed a reverse J-shaped curve and it was estimated that T. cuspidata community of this site might be maintained continuously as a stable state like present state. Annual mean radial growth of T. cuspidata populations at Seoraksan, Deokyusan, and Hallasan sites showed up as 1.27 mm/year, 0.93 mm/year and 0.89 mm/year respectively.

Estimate Saliency map based on Multi Feature Assistance of Learning Algorithm (다중 특징을 지원하는 학습 기반의 saliency map에 관한 연구)

  • Han, Hyun-Ho;Lee, Gang-Seong;Park, Young-Soo;Lee, Sang-Hun
    • Journal of the Korea Convergence Society
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    • v.8 no.6
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    • pp.29-36
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    • 2017
  • In this paper, we propose a method for generating improved saliency map by learning multiple features to improve the accuracy and reliability of saliency map which has similar result to human visual perception type. In order to overcome the inaccurate result of reverse selection or partial loss in color based salient area estimation in existing salience map generation, the proposed method generates multi feature data based on learning. The features to be considered in the image are analyzed through the process of distinguishing the color pattern and the region having the specificity in the original image, and the learning data is composed by the combination of the similar protrusion area definition and the specificity area using the LAB color space based color analysis. After combining the training data with the extrinsic information obtained from low level features such as frequency, color, and focus information, we reconstructed the final saliency map to minimize the inaccurate saliency area. For the experiment, we compared the ground truth image with the experimental results and obtained the precision-recall value.

A Design and Implementation for a Reliable Data Storage in a Digital Tachograph (디지털 자동차운행기록계에서 안정적인 데이터 저장을 위한 설계 및 구현)

  • Baek, Sung Hoon;Son, Myunghee
    • KIPS Transactions on Computer and Communication Systems
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    • v.1 no.2
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    • pp.71-78
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    • 2012
  • The digital tachograph is a device that automatically records speed and distance of a vehicle, together with the driver's activity and vehicle status at an accident. It records vehicle speed, break status, acceleration, engine RPM, longitude and latitude of GPS, accumulated distance, and so on. European Commission regulation made digital tachographs mandatory for all trucks from 2005. Republic of Korea made digital tachographs mandatory for all new business vehicles from 2011 and is widening the range of vehicles that must install digital tachographs year by year. This device is used to analyze driver's daily driving information and car accidents. Under a car accident that makes the device reliability unpredictable, it is very important to store driving information with maximum reliability for its original mission. We designed and implemented a practical digital tachograph. This paper presents a storage scheme that consists of a first storage device with small capacity at a high reliability and a second storage device with large capacity at a low cost in order to reliably records data with a hardware at a low cost. The first storage device records data in a SLC NAND flash memory in a log-structured style. We present a reverse partial scan that overcomes the slow scan time of log-structured storages at the boot stage. The scheme reduced the scan time of the first storage device by 1/50. In addition, our design includes a scheme that fast stores data at a moment of accident by 1/20 of data transfer time of a normal method.

A Study on the Solving Proportion Problems of Mathematics Textbooks and Proportional Reasoning in 6th Graders (초등학교 6학년 학생들의 교과서 비례 문제 해결과 비례 추론에 관한 연구)

  • Kwan, Mi-Suk;Kim, Nam-Gyunl
    • Journal of Elementary Mathematics Education in Korea
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    • v.13 no.2
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    • pp.211-229
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    • 2009
  • The purpose of this study is analysis of to investigate relation proportion problem of mathematics textbooks of 7th curriculum to proportional reasoning(relative thinking, unitizing, partitioning, ratio sense, quantitative and change, rational number) of Lamon's proposal at sixth grade students. For this study, I develop two test papers; one is for proportion problem of mathematics textbooks test paper and the other is for proportional reasoning test paper which is devided in 6 by Lamon. I test it with 2 group of sixth graders who lived in different region. After that I analysis their correlation. The result of this study is following. At proportion problem of mathematics textbooks test, the mean score is 68.7 point and the score of this test is lower than that of another regular tests. The percentage of correct answers is high if the problem can be solved by proportional expression and the expression is in constant proportion. But the percentage of correct answers is low, if it is hard to student to know that the problem can be expressed with proportional expression and the expression is not in constant proportion. At proportion reasoning test, the highest percentage of correct answers is 73.7% at ratio sense province and the lowest percentage of that is 16.2% at quantitative and change province between 6 province. The Pearson correlation analysis shows that proportion problem of mathematics textbooks test and proportion reasoning test has correlation in 5% significance level between them. It means that if a student can solve more proportion problem of mathematics textbooks then he can solve more proportional reasoning problem, and he have same ability in reverse order. In detail, the problem solving ability level difference between students are small if they met similar problem in mathematics text book, and if they didn't met similar problem before then the differences are getting bigger.

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