• Title/Summary/Keyword: return rate

Search Result 933, Processing Time 0.026 seconds

Effect of Intravenous Lipid Emulsion on Clozapine Acute Toxicity in Rats

  • Yousefsani, Bahareh Sadat;Mohajeri, Seyed Ahmad;Moshiri, Mohammad;Jafarian, Amir Hossein;Hosseinzadeh, Hossein
    • Journal of Pharmacopuncture
    • /
    • v.22 no.3
    • /
    • pp.147-153
    • /
    • 2019
  • Objectives: Many studies have been reported the efficacy of intravenous lipid emulsion (ILE) as an antidote on acute lipophilic drug toxicity. Clozapine, highly lipophilic dibenzodiazepine neuroleptics, is an important medication in the schizophrenia therapy regimen. Acute intoxication with antipsychotics is one of the main reasons for the referral of poisoned patients to the hospital. We expected that ILE could be used for the therapy of acute clozapine intoxicated patients. Methods: We used two groups of consisting of six male rats. Both groups received a toxic dose of clozapine (40 mg/kg) intravenously, via the tail vein. After 15 minutes, they were treated with intravenous infusion of 18.6 mg/kg normal saline (NS group), or 18.6 mg/kg ILE 20% (ILE group). We evaluated blood pressure (BP) and heart rate by power lab apparatus through the tail artery, ataxia by a rat rotary circle, seizure scores and death in multiple times after starting clozapine administration. For biochemical and pathological evaluations the samples of tissue and blood were taken. Results: Our results demonstrated that ILE 20% could return hypotension-induced clozapine better than normal saline. Furthermore, ataxia and seizure have rectified more rapidly and deaths reduced. Clozapine administration causes pancreatitis and lung injury but fat emulsion did not show an optimal effect on tissue damages caused by clozapine toxicity. Conclusion: In conclusion, ILE can remove toxic signs of clozapine same as other lipophilic medicines, however, clinical uses of ILE for this intention requires more appraisement to determine the precise implication and safety.

The Influence Factors on the Performance of Regional Public Hospitals (지방의료원의 성과에 영향을 미치는 요인)

  • Lee, Hae Jong;Lee, Dong Won;Jeong, Ji Yun
    • Health Policy and Management
    • /
    • v.29 no.1
    • /
    • pp.27-39
    • /
    • 2019
  • Background: This study is designed to estimate the factors that affect the level of three different performance (publicity, efficiency, profitability) among regional public hospitals. Methods: The units of analysis are the regional 30 hospitals, which have the operating data during 22 years (from 1933 to 2014). The research method is used by fixed panel analysis. The publicity is measured by medicaid outpatient proportion and medicaid inpatient proportion. The efficiency is measured by two types of efficient score by DEA (data envelopment analysis). The profitability is measured by medical income to medical revenue and ROA (return on total asset). Results: At first, the increase of bed gives negative affect to the publicity but give positive effect to the efficiency and profitability. Because it means the increase of the region population, it gives more profitability compare to hospital with small number of beds. The more the operating period is the higher effect to the publicity and efficiency because of it's refutation. The debt ratio gives negative effect to publicity, but positive effect to profitability. It is the normal belief that there is inverse relationship between publicity and profitability. The turnover rate of bed gives the negative affect to the publicity, but positive affect to the efficiency and profitability. That give us the implication that type of the inpatient make different effect the hospital performance. The ratio of labor cost give negative effect to all kind of performance. That means that the higher labor cost don't mean the higher publicity and labor cost control is very important factors to hospital performance. So the region hospital have to focus the labor factors more to make higher performance. Conclusion: As the conclusion, the independent variables give similar effect to the efficiency and the profitability, but give inverse effect to the publicity. That means that if an region hospital want to make the more publicity, it loss the higher efficiency and profitability. Specially publicity is higher negative relation with the profitability.

The Effects of Depreciation Methods on Investment Motivation for Solar Photovoltaic Systems (태양광 설비투자에 대한 제도적 유인방안 연구: 감가상각법의 경제적 효과 분석)

  • Kim, Kyung Nam
    • New & Renewable Energy
    • /
    • v.16 no.4
    • /
    • pp.65-75
    • /
    • 2020
  • The value of tangible assets depreciates over their useful life and this depreciation should be adequately reflected in any tax or financial reports. However, the method used to calculate depreciation can impact the financial performance of solar projects due to the time value of money. Korean tax law stipulates only one method for calculating the depreciation of solar photovoltaic facilities: the straight-line method. Conversely, USA's tax law accepts other depreciation methods as solar incentives, including the modified accelerated cost recovery system (MACRS) and Bonus depreciation method. This paper compares different depreciation methods in the financial analysis of a 10 MW solar system to determine their effect on the financial results. When depreciation was calculated utilizing the MACRS and Bonus depreciation method, the internal rate of return (IRR) was 10.9% and 16.4% higher, respectively, than when the Korean straight-line depreciation method was used. Additionally, the increased IRR resulting from the use of the two US methods resulted in a 20.5% and 27.4% higher net present value, respectively. This shows that changing the depreciation calculation method can redistribute the tax amount during the project period, thereby increasing the discounted cash flow of the solar project. In addition to increasing profitability, USA's depreciation methods alleviate the uncertainty of solar projects and provide more flexibility in project financing than the Korean method. These results strongly suggest that Korean tax law could greatly benefit from adopting USA's depreciation methods as an effective incentive scheme.

Indonesia 2017: Return of Pancasila on the Eve of the Presidential Election (인도네시아 2017: 빤짜실라의 귀환과 대선 국면의 도래)

  • SUH, Jiwon;KIM, Hyung-Jun
    • The Southeast Asian review
    • /
    • v.28 no.2
    • /
    • pp.147-179
    • /
    • 2018
  • Basuki Tjahaja Purnama, Jakarta's Ex-Governor, lost his re-election bid in 2017 and then was jailed on a charge of blasphemy. After his defeat, the rhetorics of Indonesian politics was divided into two opposing sides: anti-Communism and 'pribumi' of the radical Islamic movements and Pancasila of the Jokowi administration. Although Islamic political parties are now preoccupied with their own coalitional politics and survivals, rather than solidarity of Islamic forces, the rising Islamic sentiments confirmed by the Jakarta election indicate that religion will continue to be a key variable in Indonesian politics. Meanwhile, ex-military generals who declared themselves as candidates in the 2018 regional election and the 2019 presidential election, as well as a few measures used by the Jokowi administration against extra-parliamentary political opponents, remind us of Suharto's New Order. Steady growth continues in economy. The raise of minimum wage enlarged middle classes and led to a decline of the poverty rate. Jokowi's commitment to building infrastructure has made tangible achievements. Under these circumstances, enhanced cooperation between Indonesia and South Korea is laudable, though any such cooperation must fully incorporate local sociocultural contexts, such as the strengthened halal certification system.

Long Memory Properties in the Volatility of Australian Financial Markets: A VaR Approach (호주 금융시장 변동성의 장기기억 특성: VaR 접근법)

  • Kang, Sang-Hoon;Yoon, Seong-Min
    • International Area Studies Review
    • /
    • v.12 no.2
    • /
    • pp.3-26
    • /
    • 2008
  • This article investigates the usefulness of the skewed Student-t distribution in modeling the long memory volatility property that might be present in the daily returns of two Australian financial series; the ASX200 stock index and AUD/USD exchange rate. For this purpose we assess the performance of FIGARCH and FIAPARCH Value-at-Risk (VaR) models based on the normal, Student-t, and skewed Student-t distribution innovations. Our results support the argument that the skewed Student-t distribution models produce more accurate VaR estimates of Australian financial markets than the normal and Student-t distribution models. Thus, consideration of skewness and excess kurtosis in asset return distributions provides appropriate criteria for model selection in the context of long memory volatility models in Australian stock and foreign exchange markets.

Daesoon Jinrihoe as a Nativist Millennialism: A Comparative Study of East Asian New Religious Movements (本土性千禧年運動的建構與轉化: 以韓國大巡真理會為焦點的東亞比較研究)

  • Ting, Jenchieh
    • Journal of the Daesoon Academy of Sciences
    • /
    • v.34
    • /
    • pp.171-202
    • /
    • 2020
  • The nations of East Asia have similar historical backgrounds in terms of going through modernization during the nineteenth century. All of them commonly experienced socio-political hardships. Three of the most prosperous East Asian new religions, Yiguandao, Tenrikyo, and Daesoon Jinrihoe, all emerged under similar socio-political circumstances during the nineteenth century. There was no mutual interchange, but the cosmological perspectives share some analogous ideology. All of them were types of nativist millennialism. The ultimate goal in all three is redeeming lost elements by magical means-the sudden disappearance of invading forces, the return of mystical heroes or messiahs, and an altered landscape. As Stark said, although it is impossible to calculate the actual rate of success, probably no more than one religious movement out of 1,000 will attract more than 100,000 followers and last for as long as a century. By this standard, these three groups are certainly worthy of being studied. This paper will examine and compare these three groups through four dimensions: the Messiah's eschatology, the re-interpretation of that eschatology after the Messiah's death, the rational transformations of millennial dreams, and the institutionalization of those millennial dreams. Analytically, I could demonstrate the differences among these groups through two dimensions: (1) The dimension of time, which can be conceptualized in terms of this-worldly or other-worldly; and (2) Collective vision, which can be conceptualized in terms of utopia or reform. The cross-classification of these two dimensions is suggestive of the general avenues of Millennialism. Through these comparisons and observations, light will be shed on the essence and dynamics of East Asian Millennialist Thought by exploring deeper cultural implications.

Utilization of Evidence-Based Clinical Nursing Practice Guidelines in Tertiary Hospitals and General Hospitals (상급종합병원과 종합병원의 근거기반 임상간호실무지침의 활용도)

  • Eun, Young;Jeon, Mi Yang;Gu, Mee Ock;Cho, Young Ae;Kim, Jung Yeon;Kwon, Jeong Soon;Kim, Kyeong Sug
    • Journal of Korean Clinical Nursing Research
    • /
    • v.27 no.3
    • /
    • pp.233-244
    • /
    • 2021
  • Purpose: The purpose of this study was to investigate the actual utilization of clinical practice guidelines developed by Hospital Nurses Association. Methods: The subjects were 70 nurses who were in charge of guideline distributions in 70 advanced general hospital and general hospitals with 500 beds or more nationwide. Data were collected between June and August, 2020 by mail (return rate: 88.6%). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/WIN 24.0. Results: Among the clinical practice guidelines developed by Hospital Nurses Association, 72.9~90.1% were placed with book and electronic file in nursing department and 24.3~35.8% were placed with book and electronic file in each nursing unit at hospital. The average number of utilized clinical practice guidelines were 3.96±3.88, and average score of guideline utilization was score 2.85±0.79 which means 'use sometimes'. Conclusion: To improve the distribution and utilization of the clinical practice guidelines, it is necessary to enhance the recognition of values of evidence based nursing practice targeting head of nursing department and to stimulate the distribution and utilization of the clinical practice guidelines using diverse education programs for staff nurses.

Global Policy Responses to the COVID-19 Pandemic: Results of the ICOH Survey

  • Rondinone, Bruna M.;Valenti, Antonio;Boccuni, Valeria;Cannone, Erika;Boccuni, Fabio;Gagliardi, Diana;Dionisi, Pierluca;Barillari, Caterina;Iavicoli, Sergio
    • Safety and Health at Work
    • /
    • v.13 no.2
    • /
    • pp.141-147
    • /
    • 2022
  • Background: On the basis of its role for the development of occupational health research, information, good practices, the International Commission on Occupational Health (ICOH) launched the present survey to collect information on public health and prevention policies put in place by the governments of the countries in the world to contain the pandemic. Methods: A cross-sectional study was conducted through an online questionnaire focused on COVID-19 data, public health policies, prevention measures, support measures for economy, work, and education, personal protective equipment, intensive care units, contact tracing, return to work, and the role of ICOH against COVID-19. The questionnaire was administered to 113 ICOH National Secretaries and senior OSH experts. Collected data refer to the period ranging from the beginning of the pandemic in each country to June 30, 2020. Results: A total of 73 questionnaires from 73 countries around the world were considered valid, with a 64.6% response rate. Most of the respondents (71.2%) reported that the state of emergency was declared in their country, and 86.1% reported lockdown measures. Most of the respondents (66.7%) affirmed that the use of face masks was compulsory in their country. As for containment measures, 97.2% indicated that mass gatherings (meetings) were limited. Regarding workplace closing, the most affected sector was entertainment (90.1%). Conclusion: The results of this survey are useful to gain a global view on COVID-19 policy responses at country level.

An Economic Analysis of the Extruded Pellets on the Olive Flounder Paralichthys olivaceus Farms in the Jeju Region (제주지역 넙치(Paralichthys olivaceus) 양식업의 경제성 분석: 배합사료 공급 양식어가를 중심으로)

  • Kim, Nam-Lee;Han, Hyun-Sob;Lee, Seung-Han;Kim, Kang-Woong;Kim, Do-Hoon
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.55 no.5
    • /
    • pp.681-687
    • /
    • 2022
  • The government has implemented a policy to promote the use of extruded pellets in sustainable aquaculture by protecting fishery resources and managing the ocean environment. A survey on the production status and the cost of targeting olive flounder Paralichthys olivaceus culture farms in Jeju Island using extruded pellets was conducted. The survey results were used to examine the profitability and economic feasibility of the test farms, as well as the degree of increase in profitability and economic feasibility of the fish farms receiving government subsidies for employing extruded pellets. The economic feasibility was predicted through a sensitivity analysis of prices and production, which are the variable factors when of using the extruded pellets. Using the economic feasibility analysis, the average NPV (Net Present Value) and IRR (Internal Rate of Return) of sample farms were found to be KRW 5.8 billion and 8.9%, respectively. The result of the economic feasibility analysis of the government subsidy showed a maximum average of about 2.3 times higher NPV and a 3.8% increase in IRR in cases where government subsidies were received.

Cryptocurrency automatic trading research by using facebook deep learning algorithm (페이스북 딥러닝 알고리즘을 이용한 암호화폐 자동 매매 연구)

  • Hong, Sunghyuck
    • Journal of Digital Convergence
    • /
    • v.19 no.11
    • /
    • pp.359-364
    • /
    • 2021
  • Recently, research on predictive systems using deep learning and machine learning of artificial intelligence is being actively conducted. Due to the development of artificial intelligence, the role of the investment manager is being replaced by artificial intelligence, and due to the higher rate of return than the investment manager, algorithmic trading using artificial intelligence is becoming more common. Algorithmic trading excludes human emotions and trades mechanically according to conditions, so it comes out higher than human trading yields when approached in the long term. The deep learning technique of artificial intelligence learns past time series data and predicts the future, so it learns like a human and can respond to changing strategies. In particular, the LSTM technique is used to predict the future by increasing the weight of recent data by remembering or forgetting part of past data. fbprophet, an artificial intelligence algorithm recently developed by Facebook, boasts high prediction accuracy and is used to predict stock prices and cryptocurrency prices. Therefore, this study intends to establish a sound investment culture by providing a new algorithm for automatic cryptocurrency trading by analyzing the actual value and difference using fbprophet and presenting conditions for accurate prediction.