• The Korean Journal of Pain
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• 제34권4호
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• pp.479-486
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• 2021

Background: Prior studies have reported that 40%-90% of the patients with celiac plexus-mediated visceral pain benefit from the neurolytic celiac plexus block (NCPB), but the predictive factors of response to NCPB have not been evaluated extensively. This study aimed to identify the factors associated with the immediate analgesic effectiveness of NCPB in patients with intractable upper abdominal cancer-related pain. Methods: A retrospective review was performed of 513 patients who underwent NCPB for upper abdominal cancer-related pain. Response to the procedure was defined as (1) a decrease of ≥ 50% or ≥ 4 points on the numerical rating scale (NRS) in pain intensity from the baseline without an increase in opioid requirement, or (2) a decrease of ≥ 30% or ≥ 2 points on the NRS from the baseline with simultaneously reduced opioid consumption after NCPB. Logistic regression analysis was performed to determine the factors associated with successful responses to NCPB. Results: Among the 513 patients included in the analysis, 255 (49.8%) and 258 (50.2%) patients were in the non-responder and responder group after NCPB, respectively. Multivariable logistic regression analysis showed that diabetes (odds ratio [OR] = 0.644, P = 0.035), history of upper abdominal surgery (OR = 0.691, P = 0.040), and celiac metastasis (OR = 1.496, P = 0.039) were the independent factors associated with response to NCPB. Conclusions: Celiac plexus metastases, absence of diabetes, and absence of prior upper abdominal surgery may be independently associated with better response to NCPB for upper abdominal cancer-related pain.

• 한국과학교육학회지
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• 제22권5호
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• pp.1010-1029
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• 2002

The purpose of this research was to survey middle school students' preference for science and its causal factors, so as to analyze the causal relationships between them. Preference for science and its causal factors were defined theoretically, and a theoretical model was constructed to measure them and analyze the causal relationship by structural equation modeling. According to the theoretical model and a pilot test, a questionnaire was developed with three parts; the background information of a respondent, the preference for science, and the causal factors of preference. The questionnaire was administered to one class per grade of randomly selected 8 middle schools from 4 areas across the country, and 819 students' data were collected. Preference for science was defined as a state of mind. It revealed to what extent, and how, one likes science. It consisted of 3 categories - 'emotional response', 'behavioral volition', 'valuational comprehension', and each category was divided into two subcategories. Causal factors affecting the preference for science consisted of three categories - personal, educational and social factors, and each was divided into 2 or 3 subcategories. Middle school students' preference for science was middling as a total. Curiosity about contents of science and valuation of science were high, comparatively, but behavioral volition about science was especially low. Students' responses to the causal factors were relatively high in every educational factor and sociocultural valuation of social factors, but relatively low in socioeconomic rewards of social factors, and especially low in personal factors. The causal relationship about the preference for science was investigated by multiple regression analysis and path analysis, using the structural equation model. Multiple regression analysis about the preference for science and its causal factors revealed important factors. The important factors were personal ability, the personal traits, rewards in school science, and contents of school science in order of magnitude of standardized regression coefficient ${\beta}$. Stepwise regression analysis with each of the subcategories of the preference for science as dependent variables showed what factors were important in each subcategory. According to the result of structural equation modeling, personal factors affected 'emotional response' and 'behavioral volition' directly, and social factors affected 'valuational comprehension' directly. Educational factors affected all categories of the preference for science by influencing not only 'emotional response' and 'valuational comprehension' directly, but also 'behavioral volition' indirectly. The way to promote middle school students' preference for science was suggested, based on the analysis result.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1995년도 추계학술대회 논문집
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• pp.569-572
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• 1995

In this study, a hydraulic modulator of solenoid-flow type ABS, the master sylinder, and the wheel cylinder are modeled and simulated for increasing pressure characteristics of the brake. Response can be predicted by external force of the the master sylinder and pulses to the solenoid valve as input. For a demonstration of simulation result, experiment is done under the same condition as simulation condition after experimental apparatus of 1/4 car model is constructed. When factors of flow control valve are changed, the effect of each factor to response, how to improve response, and the most critical factors are considered from simulated result of time constant.

• 한국산업보건학회지
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• 제26권4호
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• pp.426-435
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• 2016

Objectives: The major objective of this study was to analyze stress response after a change to consecutive day shifts from day and night shifts in a motor assembly factory. Methods: Using a survey conducted by a labor union, we collected data on stress response index(SRI), lifestyle factors, work-family conflict and job stress before and after a shift system change. We analyzed the transition on the SRI among 222 workers. The cut-off point for the SRI was a T-score over 60. Results: The high risk stress response group was 20.3% of the population before the shift system change. After the shift system change it decreased to 11.3%. After the shift system change, social support improved, leisure time became more sufficient, work-family conflict declined, and sleep quality in the night shift week improved. In multivariable linear regression, among workers under 40 years old sleep quality on night shift, leisure time sufficiency, social support and work-family conflict contributed to the improvement of stress response. Among workers over 40, work-family conflict contributed to the improvement of stress response. Conclusions: The change to consecutive day shifts improved stress response and mediated with improved nighttime sleep, decreased work-family conflict, increased leisure time and improved work-family conflict.

• 한국응급구조학회지
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• 제27권1호
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• pp.19-30
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• 2023

Purpose: The study examined disaster recognition, disaster preparedness, and the willingness to participate in disaster response among healthcare students. It also identified the factors that can improve healthcare students' willingness to participate in disaster response. Methods: A structured questionnaire was designed, and data were collected from 171 students, who agreed to participate in the study at C-province between December 14, 2022, and December 28, 2022. Results: The scores of disaster preparedness and the willingness to participate in disaster response were 3.22 and 3.53, respectively. The willingness to participate in disaster response was high among those who had experienced a disaster and had disaster-related education. Furthermore, the willingness to participate in disaster response was significantly and positively correlated with disaster preparedness (r = 1.357, p<.001). Conclusion: It is important to mandate the provision of disaster preparedness education to increase the level and quality of disaster preparedness and the willingness to participate in disaster response.

• 한국지진공학회논문집
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• 제11권4호
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• pp.53-63
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• 2007

Seismic design codes are developed mainly based on the observation of the behavior of structures in the high seismicity regions where structures may experience significant amount of inelastic deformations and major earthquakes may result in structural damages in a vast area. Therefore, seismic loads are reduced in current design codes for building structures using response modification factors which depend on the ductility capacity and overstrength of a structural system. However, structures in low seismicity regions, subjected to a minor earthquake, will behave almost elastically because of the larger overstrength of structures in low seismicity regions such as Korea. Structures in low seismicity regions may have longer periods since they are designed to smaller seismic loads and main target of design will be minor or moderate earthquakes occurring nearby. Ground accelerations recorded at stations near the epicenter may have somewhat different response spectra from those of distant station records. Therefore, it is necessary to verify if the seismic design methods based on high seismicity would he applicable to low seismicity regions. In this study, the adequacy of design spectra, period estimation and response modification factors are discussed for the seismic design in low seismicity regions. The response modification factors are verified based on the ductility and overstrength of building structures estimated from the farce-displacement relationship. For the same response modification factor, the ductility demand in low seismicity regions may be smaller than that of high seismicity regions because the overstrength of structures may be larger in low seismicity regions. The ductility demands in example structures designed to UBC97 for high, moderate and low seismicity regions were compared. Demands of plastic rotation in connections were much lower in low seismicity regions compared to those of high seismicity regions when the structures are designed with the same response modification factor. Therefore, in low seismicity regions, it would be not required to use connection details with large ductility capacity even for structures designed with a large response modification factor.

• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.321-326
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• 2015

Background: The aim of this study was to explore the prognostic role of metabolic response to chemotherapy, determined by FDG-PET, in patients with metastatic non-small-cell lung cancer (NSCLC). Materials and Methods: Thirty patients with metastatic NSCLC were analyzed for prognostic factors related to overall survival (OS) and progression free survival (PFS). Disease evaluation was conducted with FDG-PET/CT and contrast-enhanced CT prior to and at the end of first-line chemotherapy. Response evaluation of 19 of 30 patients was also performed after 2-3 cycles of chemotherapy. Morphological and metabolic responses were assessed according to RECIST and PERCIST, respectively. Results: The median OS and PFS were 11 months and 6.2 months, respectively. At the end of first-line chemotherapy, 10 patients achieved metabolic and anatomic responses. Of the 19 patients who had an interim response analysis after 2-3 cycles of chemotherapy, 3 achieved an anatomic response, while 9 achieved a metabolic response. In univariate analyses, favorable prognostic factors for OS were number of cycles of first-line chemotherapy, and achieving a response to chemotherapy at completion of therapy according to the PERCIST and RECIST. The OS of patients with a metabolic response after 2-3 cycles of chemotherapy was also significantly extended. Anatomic response at interim analysis did not predict OS, probably due to few patients with anatomic response. In multivariate analyses, metabolic response after completion of therapy was an independent prognostic factor for OS. Conclusions: Metabolic response is at least as effective as anatomic response in predicting survival. Metabolic response may be an earlier predictive factor for treatment response and OS in NSCLC patients.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5687-5690
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• 2015

Background: Factors predictive of survival have been identified in Western patients with metastatic clear cell renal cell carcinoma (mCCRCC) treated with sunitinib. Less is known, however, about factors predictive of survival in Japanese patients. This study evaluated factors prognostic of survival in Japanese patients with mCCRCC treated with first-line sunitinib. Materials and Methods: This retrospective study evaluated 46 consecutive Japanese mCCRCC patients treated with sunitinib as first line therapy. Clinical and biochemical markers associated with progression-free survival (PFS) were analyzed, with prognostic factors selected by uniand multivariate Cox regression analyses. Results: Univariate analysis showed that factors significantly associated with poor PFS included Memorial Sloan-Kettering Cancer Center poor risk scores, International Metastatic RCC Database Consortium poor risk and high (>0.5 mg/dl) serum C-reactive protein (CRP) concentrations (p<0.001 each). Multivariate analysis showed that high serum CRP was independently associated with poorer PFS (p=0.040). Six month disease control rate (complete response, partial response and stable disease) in response to sunitinib was significantly higher in patients with normal (${\leq}0.5mg/dl$) than elevated baseline CRP (p<0.001). Conclusions: CRP is a significant independent predictor of PFS for Japanese patients with mCCRCC treated with first-line sunitinib. Pretreatment CRP concentration may be a useful biomarker predicting response to sunitinib treatment.

• 디자인학연구
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• 제16권4호
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• pp.423-432
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• 2003

본 연구는 제품디자인에 대한 사용자의 심리적 반응프로세스을 모형화하고 있다. 제품디자인 자체의 심미성요소에는 형태, 구조, 질감 및 색채 등이 있으며 사용자는 1차 적으로 이러한 디자인요소를 평가하게 된다. 그러나 이와같은 1차적 심미성 요소는 절대적인 가치를 갖기보다는 제품이 처한 상황, 개인적 요소 및 환경적 요소에 따라 영향을 받는다. 즉, 동일한 디자인이라 할 지라도, 가격수준, 브랜드 및 마케팅 프로그램과 같은 제품의 상황적 요소, 기호, 관여도, 개성, 라이프스타일, 인구통계변수와 같은 사용자의 개인적 요소 및 문화, 하위문화, 사회계층, 준거집단 및 가족과 같은 환경적 요소에 따라 사용자의 디자인에 대한 평가는 달라지게 된다. 사용자가 디자인을 어떻게 평가하는지에 대한 이해는 사용자에게 좋은 반응을 유발할 수 있는 디자인창출의 가능성을 높이기 위해 필요하며 또한 사용자중심디자인과 디자인마케팅의 기본적인 출발점이기도 하다. 향후 연구에서는 본 연구에서 다루지 못한 다양한 세부요소들에 대한 탐색과 각 요소 및 사용자의 반응과의 구체적인 관계에 대한 연구가 이루어져야 할 것이다.

• Journal of Biosystems Engineering
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• 제22권1호
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• pp.41-48
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• 1997

A nondestructive quality inspection technique using acoustic impulse response method was studied to investigate the feasibility of egg shell inspection. An experimental system was built to generate impact force, to measure the response signal and to analyze the frequency spectrum. This system includes an impulse generating unit, an egg holding seat, a microphone with preamplifier, and a digital oscilloscope connected to Personal Computer by RS-232C interface. The factors such as impulse generating method, egg holding method, and sensor location were evaluated by analyzing the power spectrum density of the measured signal. The results obtained are summarized as follows : 1. From the sampled eggs, the proper conditions for detecting damaged eggs were found as followings; ceramic for the impact ball material, rubber for egg seat material, 20 degrees for an impact angle of pendulum, 10mm for the distance between egg and sensor, the sharp side for impacting part, and 180 degrees for the location of sensor. 2. Examination of the Fourier transformed analysis in beth normal and damaged eggs revealed that those factors such as the resonant frequency, a number of peak frequencies and the magnitude of power spectrum were important to detect damaged eggs.