• Journal of Medicine and Life Science
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• 제17권2호
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• pp.33-40
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• 2020

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Genetic sequencing of the virus suggests that it is a beta coronavirus closely linked to the SARS virus. This disease has non-specific symptoms such as fever, dry cough, sore throat, and gastrointestinal symptoms. This virus can transmit via aerosol and need to droplet precaution to prevent spreading in public areas. Most people with COVID-19 develop only mild or uncomplicated illness. However, about 20% patients require hospitalization, oxygen supply, and intensive care. There is no currently effective treatment available for COVID-19 unresponsive to supportive care. This is review about the recently published epidemiologic, and clinical features, diagnosis, treatment and prevention of COVID-19.

• 대한치과기공학회지
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• 제17권1호
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• pp.72-81
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• 1995

The study was performed to compare the raliablity of two Korean version questionaires for respiratory symptoms and ilness being used in Korea. The subjects were 103 dental laboratory technician who divided into two groups as SUN-81-AL and SUN-93. The duration of test-retest was one two month. The differences between two groups interms of average age, height, and weight were negligible. The SUN-93 showed higher agreement compared to SUN-81-AL except items cough and smoking. The Sun-93 deserved to prefer to be used in resporatory epidemiologic study.

• 대한임상독성학회지
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• 제4권2호
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• pp.166-169
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• 2006

Poisonings caused by 'mad honey' are known to occur in response to grayanotoxins, which bind to sodium channels in the cell membrane, increasing membrane sodium permeability and preventing inactivation. Mild symptoms of mad honey intoxication are dizziness, weakness, hypersalivation, nausea, vomiting, and paresthesia. Severe intoxication, however, leads to serious cardiac manifestations such as atrioventricular block, dose-dependent hypotension, bradycardia, and respiratory depression. Atropine and vasoactive drugs improve symptoms of both bradycardia and respiratory rate depression. We report an unusual case of saliva-type hyperamylasemia in a mad honey poisoning patient who developed clinically significant bradycardia. She recovered fully within 3 days following atropine administration and medical treatment.

• Clinical and Experimental Pediatrics
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• 제63권9호
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• pp.345-354
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• 2020

The widespread and contagious coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a burden in the global health domain. The subsequent discovery of the virus features and pathogenesis, and prompt and adequate management are still lacking and remain inconclusive. Children usually present milder symptoms than adults, and management focuses on providing symptomatic and respiratory supports. Several treatment modalities, including the utilization of mechanical ventilation (MV), antivirals, immune-modulating drugs, or other agents, may present promising results in reducing the symptoms of COVID-19, particularly in severe cases. Although no randomized clinical trials have been published to date, it is interesting to explore potential modalities for treating COVID-19 in children, based on review articles, case reports, and recent guidelines.

• The Korean Journal of Medicine
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• 제99권1호
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• pp.25-31
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• 2024

Lymphangioleiomyomatosis (LAM) is a rare condition that exclusively affects women and is characterized by lung parenchymal destruction and the formation of cysts due to infiltration by LAM cells. It can also impact the lymphatic system, leading to the development of fluid-filled cystic structures and abdominal involvement, including renal angiomyolipomas (AML) or lymphangioleiomyoma. LAM can occur sporadically or be associated with tuberous sclerosis complex. Common symptoms include respiratory issues such as dyspnea, pneumothorax, chylothorax, along with other manifestations like renal AML and lymphatic involvement. The diagnosis of LAM relies on a combination of clinical, radiological, and laboratory findings, and treatment options vary depending on symptoms and patient status, with mTOR inhibitors being considered as a treatment option. This case outlines the diagnostic journey and clinical course of a 32-year-old female patient with LAM.

• Tuberculosis and Respiratory Diseases
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• 제49권2호
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• pp.162-168
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• 2000

배경 : 항결핵제 투여시 나타나는 관절 증상은 경우에 따라서는 증상의 정도가 심해 일상 생활에 영향을 미치기도 하며 약물 순응도를 저하시키기도 하므로 항결핵제 투여시 발생하는 관절 증상에 대한 이해가 필요한데 이에 대해 체계적으로 기술되어 있는 자료가 부족한 실정이다. 방법 : 6개월이상 항결핵제 33명의 환자를 대상으로 하여 치료 경과 중 특별한 다른 원인이 없이 나타나는 관절 증상에 대해 조사 하였으며 증상을 호소하지 않는 비증상군과 비교함으로써 관절 증상 발생 및 이와 관련한 위험 인자를 확인하였다. 결과 : 관절 증상을 호소하는 환자가 33명중 19명으로 증상 유병률이 58% 에 달하였으며, 증상은 약물 투여 시작 후 1.9$\pm$1.4개월에 나타나서 3.6$\pm$2.5개월 지속되었다. 한 명을 제외하고는 모두 여러 관절을 침범하며 어깨관절과 무릎 관절이 각각 10명(53%), 손가락 관절 6명(32%)으로 흔하였다. 대부분의 환자가 항결핵제의 중단 또는 변경 없이 증상이 자연 소실되었으나, 14명(74%)의 환자는 치료 중 관절 증상에 대해 진통제를 복용하였다. 원안을 확인하기는 쉽지 않았으며 PZA 이외의 약물도 증상 발현에 관여 할 것으로 보인다. 비증상군과의 비교에서 연령, 성별, 기저질환, 치료 전 및 치료 중간의 혈중 요산 농도 등에서 유의한 차이를 확인할 수 없었다. 결론 : 항결핵제 투여 중 관절 증상의 발생은 혈중 요산 농도와 관련이 없으며, 이런 증상은 PZA 이외의 다른 약제에 의해서도 유발될 수 있으므로 증상이 심해 약을 중단하거나 대체해야 할 경우 이를 고려 하여야 한다.

• Journal of Chest Surgery
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• 제28권4호
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• pp.381-386
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• 1995

In our hospital we have seen 20 cases of congenital diaphragmatic anomalies from June 1984 until December 1993. These were classified into 10 cases of diaphragmatic eventration, 8 cases of Bochdalek hernia, 1 case of Morgagni hernia, and 1 case of esophageal hiatal hernia. Diaphragmatic eventration cases were composed of 8 males and 2 females with ages varing from 3 hour to 42 year. They were discovered by symptoms: 5 cases of respiratory insufficiency; 3 cases of frequent respiratory infection; and 2 cases by chance; 6 cases involved the left side, 4 cases involved right side. Emergency operations were done to 4 patients. Among the 10 patients, only one operative mortality occurred; 3 hour old female.Bochdalek hernia cases composed 6 females and 2 males, 5 patients were less than 6 hour old. All patients were operated on an emergency status and three of them expired due to the vicious cycle of pulmonary hypertension and pulmonary vasoconstriction, persistent fetal circulation, hypoxia, and metabolic acidosis. Morgagni hernia was seen in one 69 year old female patient, she had no complaint of symptoms and was incidentally detected. Hernia was repaired through right thoracotomy. She was discharged with healthy appearence. Esophageal hiatal hernia was seen in a 10 month old male patient, his symptoms were persistent vomiting and coughing since birth. Sliding type of esophageal hiatal hernia repair was completed through left thoracotomy.

• Journal of Acupuncture Research
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• 제37권4호
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• pp.275-280
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• 2020

This study reports the effectiveness of traditional Korean medicine in treating tetraplegia and respiratory symptoms (including dyspnea) after traumatic cervical spinal cord injury surgery. The patient was treated with complex Korean medical treatment including electroacupuncture, pharmacopuncture, and herbal medicine. The manual muscle test (expanded Medical Research Council system) was used to measure the patient's muscle strength. The Korean version of the modified Barthel index and the functional independent measure were used to evaluate the patient's independence in performing daily activities. Following 2 hospitalizations and treatments, the patient's muscle strength improved > 4+ score for all joints, and the Korean version of the modified Barthel index and functional independent measure scores increased from 26 to 79 and 56 to 95, respectively. Symptoms of dyspnea, coughing, and sputum gradually improved and finally disappeared during hospitalization. This study suggests complex Korean medicine treatment may be effective in the rehabilitation of post-surgical cervical spinal cord injury patients.

• 한국임상수의학회지
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• 제35권2호
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• pp.57-59
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• 2018

A seven-month-old Hanwoo steer was presented immediately after transport with respiratory symptoms including a nasal discharge, depression, and anorexia. Though repeated treatments, bronchopneumonia had not been improved and had persisted for 10 months. Then, obstructive breath sound was heard. A cyst adjacent to the epiglottis could be observed with respiratory endoscopy. Consequently, chronic bronchopneumonia induced laryngeal cyst formation, resulting in obstructive dyspnea. And respiratory endoscopy may be useful for differentiating the causes of dyspnea in bovine clinical practice.

• 대한임상독성학회지
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• 제3권1호
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• pp.63-66
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• 2005

Toluene is an aromatic hydrocarbon found in glues, cements, and solvents. It is known to be toxic to the nervous system, hematopoietic system, and causes acid-base and electrolyte disorders. Acute respiratory failure with hypokalemia and rhabdomyolysis with acute renal failure should be considered as potential events in protracted glue sniffing. We reported the case of 26-year-old woman was admitted to the emergency department with the development of respiratory failure and altered mentality due to hypokalemia after chronic glue sniffing. She was weaned from the ventilator 3 days later after potassium and sodium bicarbonate replacement and was discharged without respiratory symptoms and other complications.