• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6932-6939
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• 2015

The respiration is one of important factor in the radiation therapy. The existing commercial method of cone-beam computed tomography on LINAC does not consider respiratory motion of patient hence the images are both distorted and inaccurate. In this study, the cone-beam computed tomography images have been reconstructed from back projection radiography of specific phase on breathing cycle which concerned about respiratory movement in radiation therapy. This study investigated how different between cone-beam CT images with and without gating respiratory movement, and this paper provides that guide and implementation of gated cone-beam CT on radiation therapeutic equipment.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.2
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• pp.69-76
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• 2020

In this paper, we introduce a method to visualize the contrast diffusion patterns and the dynamic vascular patterns in a contrast-enhanced ultrasound image sequence. We present an imaging technique to visualize parameters such as contrast arrival time, peak intensity time, and contrast decay time in contrast-enhanced ultrasound data. The contrast flow pattern and its velocity are important for characterizing focal liver lesions. We propose a method for representing the contrast diffusion patterns as an image. In the methods, respiratory motion may degrade the accuracy of the parametric images. Therefore, we present a respiratory motion tracking technique that uses dynamic weights and a momentum factor with respect to the respiration cycle. Through the experiment using 72 CEUS data sets, we show that the proposed method makes it possible to overcome the limitation of analysis by the naked eye and improves the reliability of the parametric images by compensating for respiratory motion in contrast-enhanced ultrasonography.

• 한국해양학회지
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• v.22 no.3
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• pp.191-206
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• 1987

Keum River discharges 6.4billion tons of fresh water annually into the Yellow Sea. More than 60% of the total discharge is concentrated in summer, differentiating distinct low-discharge and high-discharge periods for the estuarine environment. The concentration of SPM(Suspended Particulate Matter) is, in general, very high, except sometime during rainy season, and turbidity maximum is often observed, especially during spring-tides(Lee and Kim, 1987).

• Ocean and Polar Research
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• v.32 no.3
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• pp.177-186
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• 2010

A sequential extraction technique was used to study sediment phosphorus speciation and its relative importance in the intertidal flat of Keunso Bay during summer and winter for a better understanding of the phosphorus cycle and bioavailability in intertidal sediments. Loosely sorbed P contents were the lowest among the five P-pools and showed little seasonal or spatial variation. Although Fe-bound P contents were almost constant in winter, they decreased rapidly with sediment depth in summer. The dissolution of Fe oxides, used as an oxidant for the anaerobic respiration, ascribed the rapid decrease of Fe-bound P in summer. Al-bound P contents displayed little seasonal variation, but showed a large spatial variation, with higher values in the upper intertidal flat. Comprising about 50% of total P, Ca-bound P contents were the highest among the five P-pools. Ca-bound P contents were higher in winter than summer, but did not exhibit a clear spatial variation. Organic P contents were higher in summer than winter, which was associated with higher primary production and clam biomass in summer. Organic P contents were higher in the lower intertidal flat than the upper intertidal flat. In Keunso Bay, bioavailable P contents of the intertidal flat comprising about one third of total P ranged from 2.41 to 5.09 ${\mu}molg^{-1}$ in summer and 3.82 to 5.29 ${\mu}molg^{-1}$ in winter. The bioavailability of P contents was higher in the lower intertidal flat than the upper intertidal flat, which was attributed to the large clam production in the lower intertidal flat.

• Journal of Microbiology
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• v.41 no.1
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• pp.34-40
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• 2003

Aspergillus nidulans, a homothalic ascomycete, has a complete sexual reproductive cycle as well as an asexual one. Both sexual and asexual development are known to be genetically programmed, but are also strongly affected by environmental factors including nutrients, light, temperature and osmolarity. We have examined these factors to define favored conditions for fruiting body (cleistothecium) formation. In general, fruiting body formation was enhanced where carbon and nitrogen sources were sufficient. Limitation of C-source caused predominant asexual development while inhibiting sexual development. When higher concentrations of glucose were supplied, more cleistothecia were formed. Other carbon sources including lactose, galactose and glycerol made the fungus develop cleistothecia very well, whereas acetate caused asexual sporulation only. Organic nitrogen sources like casein hydrolysate and glycine, and an increase in nitrate or ammonium concentration also enhanced sexual development. In addition to nutrient effects, low levels of aerobic respiration, caused either by platesealing or treatment with various chemicals, favored sexual development. Carbon limitation, light exposure and a high concentration of salts promoted asexual development preferentially, suggesting that stress conditions may drive the cell to develop asexual sporulation while comfortable and wellnourished growth conditions favored sexual development.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.149-149
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• 2019

Gross Primary production (GPP) and evapotranspiration (ET) are the two critical components of carbon and water cycle respectively, linking the terrestrial surface and ecosystem with the atmosphere. The ratio between GPP to ET is called ecosystem water use efficiency (EWUE) and its quantification at the forest site helps to understand the impact of climate change due to large scale anthropogenic activities such as deforestation and irrigation. This study was conducted at the FLUXNET forest site CN-Qia (2003-2005) using Community land model (CLM 5.0). We simulated carbon and water fluxes including GPP, ecosystem respiration (ER), and ET using climatic variables as forcing dataset for 30 years (1981-2010). Model results were validated with the FLUXNET tower observations. The correlation showed better performance with values of 0.65, 0.77, and 0.63 for GPP, ER, and ET, respectively. The model underestimated the results with minimum bias of -0.04, -1.67, and -0.40 for GPP, ER, and ET, respectively. Effect of climate 'CLIM' and '$CO_2$' were analyzed based on EWUE and its trend was evaluated in the study period. The positive trend of EWUE was observed in the whole period from 1981-2010, and the trend showed further increase when simulated with rising $CO_2$. The time period were divided into two parts, from 1981-2000 and from 2001 to 2010, to identify the warming effect on EWUE. The first period showed the similar increasing trend of EWUE, but the second period showed slightly decreasing trend. This might be associated with the increase in ET in the wet temperate forest site due to increase in climate warming. Water use efficiency defined by transpiration (TR) (TWUE), and inherent-TR based WUE (IT-WUE) were also discussed. This research provides the evidence to climate warming and emphasized the importance of long term planning for management of water resources and evaporative demand in irrigation, deforestation and other anthropogenic activities.

• The Korean Journal of Nuclear Medicine Technology
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• v.19 no.2
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• pp.63-67
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• 2015

Purpose Among various causes that influence image quality degradation, various methods for decrease in Artifact occurred by respiration of patients are being used. Among them, this study intended to evaluate CTAC Shift correction method and additional scan compare to the Scan(Q static scan) using respiratory gated system. Materials and Methods This study was conducted on 10 patients, and used PET-CT Discovery 710 (GE Healthcare, MI, USA) and Varian's RPM system. 5.18 Mbq per kg of $^{18}F$-FDG was injected on patients, asked them to take a rest for 1 hour in the bed, and conducted test after urination. Images were visualized through Q static scan, CTAC Shift correction method, Additional scan based on the Whole body scan(WBS) with Artifact. Decrease in Artifact was compared in each image, conducted Gross Evalution, and measured changes of SUVmax. Results For image obtained through the CTAC Shift correction method through WBS with Artifact, 12~56%, Q static scan image showed 17~54% of change rate and Additional Scan showed -27~46% of change rate. In Blind Test, the CTAC Shift correction image showed the highest point with 4 points, Q static scan image showed 3.5 points, and Additional scan image showed 3.4 points. The standardized WBS scan through Oneway ANOVA and three types of Scan method showed significant difference(p<0.05), and did not show significant difference between the three Scan methods(p>0.05). However, the three Scan methods showed significant difference in Blind test. Conclusion Additional scan and Q static scan require more time than the CTAC Shift correction method, there is concern about excessive exposure to patients by CT rescan and Q static scan is difficult to apply on patients with inconsistent respiration or irregular respiration cycle due to pain. For CTAC Shift correction method, limited correction is possible and the range is limited as well. It is considered as a useful method of improving diagnostic value when hospitals use the system appropriately and develop various advantageous factors of each method.

• Radiation Oncology Journal
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• v.26 no.3
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• pp.181-188
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• 2008

Purpose: In order to enhance the efficiency of respiratory gated 4-dimensional radiation therapy for more regular and stable respiratory period and amplitude, a respiration training system was designed, and its efficacy was evaluated. Materials and Methods: The experiment was designed to measure the difference in respiration regularity following the use of a training system. A total of 11 subjects (9 volunteers and 2 patients) were included in the experiments. Three different breathing signals, including free breathing (free-breathing), guided breathing that followed training software (guided-breathing), and free breathing after the guided-breathing (post guided-breathing), were consecutively recorded in each subject. The peak-to-peak (PTP) period of the breathing signal, standard deviation (SD), peak-amplitude and its SD, area of the one cycle of the breathing wave form, and its root mean square (RMS) were measured and computed. Results: The temporal regularity was significantly improved in guided-breathing since the SD of breathing period reduced (free-breathing 0.568 vs guided-breathing 0.344, p=0.0013). The SD of the breathing period representing the post guided-breathing was also reduced, but the difference was not statistically significant (free-breathing 0.568 vs. guided-breathing 0.512, p=ns). Also the SD of measured amplitude was reduced in guided-breathing (free-breathing 1.317 vs. guided-breathing 1.068, p=0.187), although not significant. This indicated that the tidal volume for each breath was kept more even in guided-breathing compared to free-breathing. There was no change in breathing pattern between free-breathing and guided-breathing. The average area of breathing wave form and its RMS in postguided-breathing, however, was reduced by 7% and 5.9%, respectively. Conclusion: The guided-breathing was more stable and regular than the other forms of breathing data. Therefore, the developed respiratory training system was effective in improving the temporal regularity and maintaining a more even tidal volume.

• Journal of the Korean Society of Radiology
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• v.5 no.4
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• pp.179-187
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• 2011

This study statistically analyzed the difference of the stability of maintaining a respiratory period shown according to position and use of a device to search the tendency and usefulness of a device. The supine position showed better maintaining respiratory cycles than the prone position. The 85% of subjects who showed bad maintenance pattern of a respiratory cycle were significantly different pattern with using belly board. It could be said that there was a significant correlation between the maintenance of a respiratory cycle and relative index of respirational stability(p=0.044, kappa=0.607). The movement due to respiration was one of important considerations in the radiation therapy on chest, abdomen, and even pelvis. This study could contribute to the high quality radiation therapy by statistic analysis of respiratory signals and its application.

• 대한방사선치료학회:학술대회논문집
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• 2005.06a
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• pp.13-17
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• 2005

Introduction : For stereotactic radiosurgery (SRS) of a tumor in the region whose movement due to respiration is significant, like Lung lower lobe, the gated therapy, which delivers radiation dose to the selected respiratory phases when tumor motion is small, was peformed using the Respiratory gating system and its clinical effectiveness was evaluated. Methode and Materials : For two SRS patients with a tumor in Lung lower lobe, a marker block (infrared reflector) was attached on the abdomen. While patient' respiratory cycle was monitored with Real-time Position Management (RPM, Varian, USA), 4D CT was performed (10 phases per a cycle). Phases in which tumor motion did not change rapidly were decided as treatment phases. The treatment volume was contoured on the CT images for selected treatment phases using maximum intensity projection (MIP) method. In order to verify setup reproducibility and positional variation, 4D CT was repeated. Result : Gross tumor volume (GTV) showed maximum movement in superior-inferior direction. For patient $\#$1, motion of GTV was reduced to 2.6 mm in treatment phases ($30\%\~60\%$), while that was 9.4 mm in full phases ($0\%\~90\%$) and for patient $\#$2, it was reduced to 2.3 mm in treatment phases ($30\%\~70\%$), while it was 11.7 mm in full phases ($0\%\~90\%$). When comparing two sets of CT images, setup errors in all the directions were within 3 mm. Conclusion : Since tumor motion was reduced less than 5 mm, the Respiratory gating system for SRS of Lung lower lobe is useful.