• Title/Summary/Keyword: resistance management

Search Result 994, Processing Time 0.028 seconds

Adiponectin gene SNP 276G${\rightarrow}$T, nutrient intakes, and cardiovascular disease risk in Korean type 2 DM patients

  • Yu, So-Young;Ryu, Han-Kyoung;Park, Hee-Jung;Choi, Young-Ju;Huh, Kap-Bum;Kim, Wha-Young
    • Nutrition Research and Practice
    • /
    • v.1 no.4
    • /
    • pp.363-370
    • /
    • 2007
  • Single nucleotide polymorphism (SNP) in adiponectin gene has been associated with insulin resistance, diabetes, and cardiovascular disease (CVD). This study was performed to investigate the association of SNP 276G${\rightarrow}$T at adiponectin gene with CVD risk factors in Korean type 2 diabetes mellitus (DM) patients. The subjects were 351 type 2 DM patients visited a DM clinic in Seoul, and the patients with known CVD were excluded. The adiponectin SNP 276G${\rightarrow}$T was analyzed and dietary intakes were assessed by a Food Frequency Questionnaire. The prevalence of G/G, G/T, and T/T genotype was 47.6%, 43.3%, and 9.1%, respectively. Male subjects with T/T genotype showed significantly lower level of adiponectin and HDL-cholesterol and significantly higher C-reactive protein (CRP) level compared to G/G and G/T genotypes. In G/G genotype, protein intake was negatively correlated to body weight, BMI, and waist circumference, and there were positive correlation between carbohydrate intake and BMI, waist-hip ratio, and ApoB/apoA-1 ratio in G/T genotype. However, in T/T genotype, there was no significant association between macronutrient intakes and anthropometric and hematological values. In conclusion, CVD risk would be high in type 2 DM patients with T/T genotype, and the association of macronutrient intakes with anthropometric and hematologic factors was different among the three adiponectin genotypes. These results may imply the need for different dietary management regime according to adiponectin genotype to lower CVD complications in Korean type 2 DM patients.

A Study on Factors Affecting the Relationship between Organizational Context for Work Innovation and Intention of ERP Extension Usage (업무혁신에 대한 조직적 상황과 ERP시스템의 확장이용의도 간의 관계에 영향을 미치는 요인에 관한 연구)

  • Jang, Gil-Sang;Song, Jung-Su
    • The Journal of Information Systems
    • /
    • v.21 no.1
    • /
    • pp.153-172
    • /
    • 2012
  • The purpose of this study is twofold: first, to identify the factors affecting the relationships between the organizational context for work innovation(organizational citizenship behaviors, IS innovation resistance, and user IT capability) and the intention of ERP extension usage, and second, to examine the mediating effect of the ERP performance on the relationships between the ERP adaptation and the intention of ERP extension usage. In order to achieve the goals of this study, data were obtained from 304 members of the seven organizations such as manufacturers, distributors and service industries, and were analyzed by using SPSS 12.0 and AMOS 5.0. The study results are as follows. There were positive effects of the organizational citizenship behaviors and the user IT capability on the change management activity. The IS innovation resistance had a negative effects on the change management activity. The change management activity had a positive effect on the ERP adaptation. The ERP adaptation had a positive effect on the ERP performance and the intention of ERP extension usage. The ERP performance had a positive effect on the intention of ERP extension usage. In addition, there was a partial mediating effect of the ERP performance on the relationships between ERP adaptation and intention of ERP extension usage. Based on these findings, the implications and limitations of the study were presented including some directions for future studies.

An Empirical Study on Users' Resistance against the Smart work: Based on the Organization's Innovative Characteristics and the User Characteristics (조직의 혁신성과 사용자 특성이 스마트워크 사용자 저항에 미치는 영향)

  • Oh, Seung Hun;Chae, Myungsin
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.18 no.4
    • /
    • pp.191-200
    • /
    • 2017
  • Smart work is an alternative form to enable seamless business collaboration without time and space limitations using ICT. However, smart work implementation has not produced tangible achievements and sometimes has resulted in failure. This study examined users' resistance against smart work, which is regarded as one of the most important elements for the successful implementation of smart work. The study classified elements which cause users' resistance into the work's innovative characteristics and the user characteristics based on the model of innovation resistance. It also set the degree of freedom in spatial and temporal dimension as moderating factors. This empirical research results showed that low work efficiency, unfavorable evaluation methods, and high degree of satisfaction in the way of working affected smart work users' resistance. In addition, temporal freedom had a moderating effect on the relationship between users' characteristics and their resistance. On the contrary, spatial freedom affected the relationship between their works' innovative characteristics and their resistance. The study results suggest that organizations need to set up business processes and evaluation methods first to adopt Smart work successfully.

An Improvement of Expendable Bathythermograph Measurement Mechanism for Anti-Submarine Warfare (대잠용 수온측정계 측정 메커니즘 개선)

  • Shin, Sang-Sik;Cho, Hwan Hwi;Park, Seung Soo
    • Journal of Korean Society for Quality Management
    • /
    • v.42 no.3
    • /
    • pp.301-310
    • /
    • 2014
  • Purpose: The purpose of this study is to improve a mechanism of expendable bathythermograph measurement by balancing wire resistances between plus wire part and minus wire part and by removing effects of sea water resistance between XBT(Expendable Bathythermograph) and temperature recorder. Methods: The problems are exactly found out through the analysis of XBT and temperature recorder circuit. A process of XBT manufacturing that balances wire resistances between plus wire part and minus wire part is added. Results: The results of this study are as follows; the complicated test process such as temperature accuracy test with a cistern is substituted with a simple process of XBT manufacturing such as balancing wire resistances between plus wire part and minus wire part. Then, the temperature accuracy tolerance of XBT is improved up to ${\pm}0.1^{\circ}C$. Conclusion: Consequently, balancing wire resistances and removing effects of sea water resistance improve temperature accuracy of XBT and reduce expensive and harassing process of XBT manufacturing.

Control of Avian Coccidiosis : Past, Present, and Future (닭 콕시듐병 방제의 과거, 현재, 그리고 미래)

  • Ruff, M.D.
    • Korean Journal of Poultry Science
    • /
    • v.19 no.3
    • /
    • pp.151-160
    • /
    • 1992
  • Control of coccidiosis depends on medication, management, immunity, or some combination of these methods. Prophylactic medication with anticoccidials remains the primary method of control, although the development of drug resistance is a major problem. Shuttle and rotation programs are increasingly used to delay the onset of drug resistance. Sensitivity testing has become an important tool in the identification of what specific medications will be effective in specific poultry operations. Management techniques for the control of coccidiosis have not been totally effective because most disinfectants do not kill the coccidial oocysts. Present methods for vaccination are currently limited to the use of controlled doses of live coccidia. New vaccination methods under investigation include vaccination with attenuated strains or parasite antigens produced either by fractionating the parasites or genetically engineered sub unit vaccines.

  • PDF

Study of the BIA component analysis for medical device companies (의료기기 기업을 위한 BIA 성분분석에 대한 연구)

  • Park, Eun Ju;Park, Roh Gook
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.9 no.6
    • /
    • pp.145-152
    • /
    • 2014
  • This Study was done to estimate the availability of biological resistance analysis method in medical equipment companies in Korea, and if it is usefull in predicting risk of obesity and cardiovascular disease and managing of it, by means of comparing it with blood tests. Especially, we analyzed the correlation between circumference length and fat thickness of each site of body area, which are ones of among measurement values of the BIA. This study has the purpose to propose the use of BIA as basement of diagnosis for efficient management and assessment in the medical device industry in our country.

  • PDF

Risk Assessment of Growth Hormones and Antimicrobial Residues in Meat

  • Jeong, Sang-Hee;Kang, Dae-Jin;Lim, Myung-Woon;Kang, Chang-Soo;Sung, Ha-Jung
    • Toxicological Research
    • /
    • v.26 no.4
    • /
    • pp.301-313
    • /
    • 2010
  • Growth promoters including hormonal substances and antibiotics are used legally and illegally in food producing animals for the growth promotion of livestock animals. Hormonal substances still under debate in terms of their human health impacts are estradiol-$17\beta$, progesterone, testosterone, zeranol, trenbolone, and melengestrol acetate (MGA). Many of the risk assessment results of natural steroid hormones have presented negligible impacts when they are used under good veterinary practices. For synthetic hormonelike substances, ADIs and MRLs have been established for food safety along with the approval of animal treatment. Small amounts of antibiotics added to feedstuff present growth promotion effects via the prevention of infectious diseases at doses lower than therapeutic dose. The induction of antimicrobial resistant bacteria and the disruption of normal human intestinal flora are major concerns in terms of human health impact. Regulatory guidance such as ADIs and MRLs fully reflect the impact on human gastrointestinal microflora. However, before deciding on any risk management options, risk assessments of antimicrobial resistance require large-scale evidence regarding the relationship between antimicrobial use in food-producing animals and the occurrence of antimicrobial resistance in human pathogens. In this article, the risk profiles of hormonal and antibacterial growth promoters are provided based on recent toxicity and human exposure information, and recommendations for risk management to prevent human health impacts by the use of growth promoters are also presented.

Analysis of the thermal management of a high power LED package with a heat pipe

  • Kim, Jong-Soo;Kim, Eun-Pil
    • Journal of Advanced Marine Engineering and Technology
    • /
    • v.40 no.2
    • /
    • pp.96-101
    • /
    • 2016
  • The thermal management of high-power LED components in an assembly structure is crucial for the stable operation and proper luminous function. This study employs numerical tools to determine the optimum thermal design in LEDs with a heat sink consisting of a crevice-type vapor-chamber heat pipe. The effects of the MCPCB are investigated in terms of the substrate thicknesses on which the LEDs are mounted. Further, different placement configurations in a system module are considered. This study found that for a confined area, a power of 40 W/LED is applicable to a high-power package. Furthermore, the thermal conductivity of dielectric layer materials should ideally be greater than 0.9 W/m.K. The temperature conditions of the vapor chamber in a heat pipe greatly affect the thermal performance of the system. At an offset distance of 9.0 mm and a $2^{\circ}C$ increase in the temperature of the heat pipe, the resulting maximum temperature increase is approximately $1.9^{\circ}C$ for each heat dissipation temperature. Finally, at a thermal conductivity of 0.3 W/m.K, it was found that the total thermal resistance changes dramatically. Above 1.2 W/m.K, the resistance change reduces exponentially.

Detection Algorithm and Extract of Deviation Parameters for Battery Pack Based on Internal Resistance Aging (저항 열화 기반의 배터리 팩 편차 파라미터 추출 방안 및 검출 알고리즘)

  • Song, Jung-Yong;Huh, Chang-Su
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.31 no.7
    • /
    • pp.515-520
    • /
    • 2018
  • A large number of lithium-ion batteries are arranged in series and parallel in battery packs, such as those in electric vehicles or energy storage systems. As battery packs age, their output power and energy density drop because of voltage deviation, constant and non-uniform exposure to abnormal environments, and increased contact resistance between batteries; this reduces application system efficiency. Despite the balancing circuit and logic of the battery management system, the output of the battery pack is concentrated in the most severely aged unit cell and the output is frequently limited by power derating. In this study, we implemented a cell imbalance detection algorithm and selected parameters to detect a sudden decrease in battery pack output. In addition, we propose a method to increase efficiency by applying the measured testing values considering the operating conditions and abnormal conditions of the battery pack.

A Study on the Electrical Properties of Ethylene Propylene Rubber by Thermal Treatment and Irradiation (방사선 및 열처리에 의한 에틸렌프로필렌 고무의 전기적 특성에 관한 연구)

  • 이성일
    • Journal of the Korea Safety Management & Science
    • /
    • v.4 no.4
    • /
    • pp.137-146
    • /
    • 2002
  • In order to investigate the effect of irradiation by $^{60}Co-\gamma$rays as well as the e thermal treatment on the dielectric deterioration in ethylene propylene rubber, insulating material for electric cables used in atomic power plants, charging discharging current, residual built- up voltage and dielectric properties are measu discussed in this study. Variance in the characteristic of relative dielectric constant as a function of tem was observed in relatively high dose of irradiation. Since glass transition tem appeared at tens of degree Celsius below zero, the characteristic is attributed orientation polarization. Dielectric loss is generally increased, with increasing d irradiation in the characteristic of dielectric loss as a function of temperature, No d loss by thermal treatment was observed. Dielectric resistance decreases with increa of irradiation in the characteristic of charging current as a function of temperature be considered that dielectric resistance seems to be recovered by thermal treatm characteristic of discharging current as a function of time in the specimen less ir become similar to that of the unirradiated, when thermal treated. A peak is shown residual built- up voltage as a function of time, and the corresponding time of the shorten as increasing dose of irradiation. It is also observed that the corresponding the peak is lengthened by thermal treatment.