• Advances in concrete construction
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• 제8권2호
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• pp.127-137
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• 2019

Roller Compacted Concrete (RCC) is a zero slump concrete consisting of a mixture of cementitious materials, sand, dense graded aggregates and water. In this study, an attempt has been made to investigate the effect of aggregate type on strength and abrasion resistance of RCC made by using granulated blast furnace slag (GGBS) as partial replacement of cement. Mix proportions of RCC were finalized based upon the optimum water content achieved in compaction test. Two different series of RCC mixes were prepared with two different aggregates: crushed gravel and limestone aggregates. In both series, cement was partially replaced with GGBS at a replacement level of 20%, 40% and 60%. Strength Properties and abrasion resistance of the resultant mixes was investigated. Abrasion resistance becomes an essential parameter for understanding the acceptability of RCC for rigid pavements. Experimental results show that limestone aggregates, with optimum percentage of GGBS, perform better in compressive strength and abrasion resistance as compared to the use of crushed gravel aggregates. Observed results are further supported by stoichiometric analysis of the mixes by using basic stoichiometric equations for hydration of major cement compounds.

• 한국지반환경공학회 논문집
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• 제16권6호
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• pp.5-11
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• 2015

최근 구조물 기초 분야에 대한 한계상태설계법이 국제적인 기술표준으로 요구됨에 따라 연구기반이 미약한 얕은기초에 대한 하중저항계수설계법 개발의 필요성이 대두되었다. 본 연구에서는 얕은기초 설계 시 풍화토 지반에 위치한 얕은기초에 대한 하중저항계수설계법의 적용 방안에 대하여 연구를 수행하고 그에 따른 저항계수를 제안하였다. 얕은기초 국내 설계 및 시공자료를 수집하여 확률통계학적 기법에 의한 분석을 수행함으로써 풍화토지반 얕은기초의 불확실성과 저항편향계수를 정량적으로 분석하고, 신뢰성 해석 LEVEL II를 이용하여 목표신뢰도 지수를 평가하였으며, 산정된 신뢰도지수를 기존 문헌 값과 비교 분석하여 풍화토 지반 얕은기초에 대한 목표신뢰도 지수를 선정하였다. 국내 풍화토지반 얕은기초에 대한 하중계수를 적용하여 저항계수를 보정하였으며, AASHTO의 하중계수를 적용한 저항계수와 비교 분석하였다.

• Animal Bioscience
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• 제35권1호
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• pp.138-146
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• 2022

Objective: The objective of the current study was to investigate the influences of conventional (CO) and deep litter (DE) systems on antimicrobial resistance in fecal Escherichia coli (E. coli). Methods: A cross-sectional study was carried out to detect antimicrobial resistance to E. coli in swine fecal samples in CO and DE systems located in western and northeastern Thailand. Individual rectal swab samples were taken only from healthy pigs. A total of 215 individual and healthy pigs were randomly selected for isolation and antimicrobial susceptibility test of E. coli by the disc diffusion method. The test panel included amoxicillin (AMX), colistin, doxycycline (DOX), enrofloxacin, gentamicin (GEN), kanamycin, neomycin (NEO), and trimethoprim-sulfamethoxazole (SXT). Results: There were significant (p<0.05) lower resistance levels for GEN, NEO, and SXT in the DE farms compared to those in the CO farms. There was a lower number of antimicrobial resistance agents (p<0.001) in the DE farms compared to those in the CO farms. This result was consistent with those in western (p<0.01) and northeastern (p<0.01) Thailand. Overall, antibiograms of AMX-SXT and AMX-DOX-SXT were found in the CO (19.09% and 20.91%, respectively) and the DE (16.19% and 24.76%, respectively) farms. No antimicrobial resistance (5.71%) was found and AMX (13.33%) resistant pigs in the DE farms, whereas the pattern of AMX-GEN-SXT (6.36%) and AMX-DOX-GEN-SXT (11.82%) resistant pigs was found in the CO farms. Conclusion: The DE system for pig farming was superior to conventional pig farming by lowering the resistance level of fecal E. coli to GEN, NEO, and SXT, with decreasing the number of antimicrobial resistance agents and inducing a small proportion of pigs to be free from antimicrobial resistance.

• Journal of Yeungnam Medical Science
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• 제12권2호
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• pp.269-281
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• 1995

포도당 중합체 투여로 유도한 고혈당 및 고인슐린 혈증이 인슐린 저항성의 발생에 미치는 영향을 규명하기 위하여 hyperinsulinemic euglycemic clamp 기법으로 측정한 당제거율, 당주입율 및 간의 당생성율과 방사성동위원소를 이용한 골격근의 당원질합성능을 측정한 본 연구결과를 요약하면 다음과 같다. Hyperinsulinemic euglycemic clamp 기법으로 평형상태에서 측정한 당제거율은 포도당 중합체군에서 혈중 인슐린의 생리적 및 최대농도 모두에서 정상대조군에 비해서 감소하였으며(p<0.05) STZ 당뇨군에서도 최대인슐린 농도에서 감소하였다(p<0.05). 당 주입율은 생리적 인슐린 농도에서 포도당 중합체군에서 감소하는 경향을 보였으나 최대인슐린 농도에서는 포도당 중합체군과 STZ 당뇨군에서 다같이 유의한 감소를 보였다(p<0.05). 간의 당생성율은 포도당 중합체군에서 생리적 및 최대인슐린 농도에서 다같이 감소하는 경향이었으며, 최대농도군에서는 유의하게 감소(p<0.05)하였다. STZ 당뇨군에서는 최대인슐린 농도에서 정상대조군 및 포도당 중합체군보다 증가하였다(p<0.05). 골격근과 간의 당원질 합성능은 포도당 중합체군이 정상 대조군과 차이가 없었으나 STZ 당뇨군에서는 감소하였다(p<0.05). 이상의 결과로 볼때 포도당 중합체투여로 유도한 고혈당 및 고인슐린증시 말초조직의 인슐린 저항성이 유발되었으나 soleus근과 간의 당원 합성은 장애가 없어서 STZ 당뇨군과 차이를 나타내었다.

• 한국응용곤충학회지
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• 제63권1호
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• pp.33-42
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• 2024

복숭아혹진딧물(Myzus persicae)은 다식성으로 담배, 감자, 고추, 배추, 복숭아 등에 심각한 피해를 입히는 대표적인 농업해충이다. 본 연구에서는 국내 복숭아혹진딧물 야외개체군의 λ-cyhalothrin, imidacloprid 및 flupyradifurone에 대한 약제 저항성 발달 수준과 점 돌연변이(R81T, L1014F, M918L)의 발생 여부를 확인하였다. 또한, qRT-PCR을 통해 사이토크롬 P450 유전자인 CYP6CY3 발현량을 확인하였다. 그 결과, λ-cyhalothrin은 저항성비(Resistance Ratio, RR)가 12개 모든 지역이 > 200으로 높은 저항성을 보였다. Imidacloprid와 flupyradifurone은 YS, UR, HY, 그리고 WJ 개체군에서 > 200의 저항성비로 높은 저항성을 나타냈다. R81T는 12개 집단 중 약 50%, L1014F는 약 33.3%, M918L은 100%에서 발현하였다. 또한 qRT-PCR을 통해 imidacloprid 저항성 개체에서 subunit CYP6CY3의 발현량이 높게 나타난 것을 확인하였다. 이러한 결과는 M918L 점 돌연변이는 λ-cyhalothrin 저항성 진단마커로, R81T와 CYP6CY3의 높은 발현은 imidacloprid 저항성 진단마커로 활용이 가능하다는 것을 시사한다.

• 대한한방내과학회지
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• 제33권4호
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• pp.429-437
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• 2012

Objectives : Obesity is an important cause of diabetes, and lipotoxicity causes insulin resistance. In this study, we investigated the effects of Salvia miltiorrhiza on high fat diet-induced obese type 2 diabetic mouse models. Methods : Diabetes was induced in ICR male mouse (23~25 g) with Surwit's high fat, high sucrose diet. Mice were divided into 4 groups (n=10) of normal, control, Salvia miltiorrhiza, and metformin. After 8 weeks, body weight, OGTT, fructosamine, lipid profile, serum level of adiponectin and leptin, epididymal fat pad, liver weight and epididymal adipocyte size were measured. Results : Salvia miltiorrhiza significantly reduced oral glucose tolerance levels, fructosamine serum level, epididymal fat weight, and epididymal adipocyte size. Salvia miltiorrhiza also increased HDL-cholesterol, adiponectin and leptin serum levels. Conclusions : These results show that Salvia miltiorrhiza improves insulin resistance. Therefore we suggest that Salvia miltiorrhiza would be an effective treatment for obese type 2 diabetic patients.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.1195-1205
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• 2008

Composite piles have been used in ground conditions where conventional piles are unsuitable or uneconomical. They may consist of a combination of timber and concrete pile in Europe. One method of doing this was to drive a steel tube to just below water level, and a concrete pile was lowered down it and driven to the required level where corrosion was susceptible in U.K. Recently, a fiber reinforced polymer (FRP) composite pile was developed to use in many marine locations for piers and waterfront buildings in the USA(Hoy, 1995; Phair, 1997). A steel composite (SC) pile reinforced concrete spun pile with steel tube was also proposed and used for the foundation acting a high lateral earthquake load. Composite piles have been developed and researched to increase lateral resistance or to prevent corrosion in marine structures. In paper, the composite pile consisting of the steel upper portion and the concrete lower portion is proposed and are carried out several tests to confirm the capacity of the pile such as lateral load test, dynamic load tests and bending test. It is noted that the composite pile would be a economical pile being capable of increasing lateral resistance.

• Asian-Australasian Journal of Animal Sciences
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• 제22권4호
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• pp.465-470
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• 2009

The chicken Mx gene has been regarded as a candidate gene for resistance to avian influenza virus (AIV). In this study, three groups of chickens with homozygotes (AA, GG) and heterozygotes (AG) of the resistant (A) and susceptible alleles (G) to AIV of the Mx gene were constructed from a line of dwarf egg-type chickens. These chickens were not examined for their resistant activities to AIV because the differential resistance had only been detected in vitro. The birds of the three groups were vaccinated with inactivated H5N2 AIV vaccine and the level of hemagglutination inhibition (HI) antibody to AIV was detected. The association between disease resistant activity to AIV and antibody response to AIV vaccination in the three groups was analyzed. The chickens with homozygous resistant allele A showed the lowest antibody levels, whereas the heterozygous chickens (AG) presented the highest antibody level after the boosting vaccination, which indicates that the efficiency of artificial selection on the resistant allele of Mx gene will be compromised since the homozygotes of the allele presented the weakest antibody response to the corresponding vaccine.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2009년도 춘계 학술논문 발표대회 학계
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• pp.239-242
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• 2009

As the high-rise building increase due to the gravitation of population to big cities recently, it requires high quality and high performance of Concrete. As a result, people are keenly interested in Meta-kaolin as new admixture favorable from an economic perspective, which has strength and endurance with admixture at the same level like Silica-fume. Accordingly, as to Meta-kaolin, this study was to set by three levels like domestic one, foreign one, and Silica-fume, the water-binding material ratio 25%, and four level substitute like 0, 10, 20, and 30(%) in order to compare and analyze the quality durability of high-concrete according to the substitute of Meta-kaolin applicable with replacement of Silica-fume. As a result of performing experiment it was found that when water-binding material ratio increases, resistance of neutralization, carbonation, salt damage and sulfate decrease, and when replacement ratio of mineral admixture increases, depth of accelerating carbonation gets greater. Also, the combination of SF and MK-B favored resistance to chloride ion penetration better than MK-A, and it was found that when replacement ratio of binding material increases, the resistance to sulphuric acid increases. Therefore, based on this study, it was understood that meta-kaolin is useable in replacement of silicafume.

• 한국환경복원기술학회지
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• 제5권4호
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• pp.19-30
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• 2002

The stability of slope using root-pile like to the reinforcements is affected by the interaction behavior mechanism of soil-reinforcements. Through the studying on the interaction in joint of its, therefore, the control roles can be find out in installed slope. In study, the stress level ratio based on the insert angle of installed reinforcements in soil used to numerical analysis, which was results from the duty direct shear test in Lab. The maximum shear strain variation on the reinforcements was observed at insert angle, which was approximately similar to the calculated angle based on the equation proposed by the Jewell. The elasto-plastic joint model on the contact area of soil-reinforcements was presumed, the reinforced soil assumed non-linear elastic model and the reinforcements supposed elastic model, respectively. The finite element analysis of assumed models was performed. The shear strain variation of non-reinforced state obtained by the FEM analysis including elasto-plastic joint elements were shown the rationality of general limit equilibrium analysis for the slope failure mode on driving zone and resistance zone, which based on the stress level step according to failure ratio. Through the variation of shear strain for the variation of inserting angle of reinforcements, the different mechanism on the bending and the shear resistance of reinforcements was shown fair possibility.