• Title/Summary/Keyword: resistance diagnosis

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Rapid diagnosis and control of sulfonylurea resistant Monochoria korsakowii (Sulfonylurea계 제초제 저항성 물옥잠의 조기진단과 방제)

  • Park, Tae-Seon;Moon, Byeong-Chul;Cho, Jeong-Rae;Kim, Chang-Suk;Kim, Moo-Sung;Kim, Kil-Ung
    • The Korean Journal of Pesticide Science
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    • v.8 no.1
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    • pp.63-70
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    • 2004
  • Sulfonylurea(SU)-resistant Monochoria korsakowii has resently been found in rice fields in Korea. A quick, practical and accurate test of confirming herbicide resistance is necessary to take timely management decision. This article describes a rapid reliable assay to detect SU-resistant biotype of Monochoria korsakowii. Up to now, the resistance to SU has been usually checked by application seedlings with herbicide. This application technique is time consuming and not practical. Therefore, we have developed efficient, rapid and practical diagnosis which allow easy detection of the SU-resistant Monochoria korsakowii by survival rate and regenerated plant length to herbicide application after cutting plants $0.5\sim1cm$ from the planted surface. This new rapid diagnosis can determine the SU resistance of the Monochoria korsakowii within 7 days at least. If the resistance of Monochoria korsakowii is identified by the rapid diagnosis, the selection of herbicide according to the stages of plants for the effective control is very important. The resistant biotype which treated with SU herbicide-based mixtures survived from the fields could effectively be controlled by soil application of butachlor+pyrazolate GR or by foliar application of the mixtures of bentazone SL and 2,4-D SL.

Fault Diagnosis Scheme for Open-Phase Fault of Permanent Magnet Synchronous Motor Drive using Extended Kalman Filter (영구자석 동기전동기 드라이브의 확장형 칼만필터를 이용한 개방성 고장진단 기법)

  • Ahn, Sung-Guk;Park, Byoung-Gun;Kim, Rae-Young;Hyun, Dong-Seok
    • The Transactions of the Korean Institute of Power Electronics
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    • v.16 no.2
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    • pp.191-198
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    • 2011
  • In this paper, the fault diagnosis scheme for PMSM drives has been proposed to maintain control performance under a switch open-phase fault of inverter. When the open-phase fault occurs, the stator resistances of PMSM are estimated by Extended Kalman Filter (EKF) in real time and can appear differently according to the location of fault occurrence to check the fault detection and identification. The control algorithm is configured without the additional device and low cost by adding the existing control program. Also, by using motor parameter the estimated stator resistance value improves the control performance of the controller affected by parameter variation. The feasibility of the proposed fault diagnosis algorithm is validated in simulation and experiment.

High Expression of Lung Resistance Protein mRNA at Diagnosis Predicts Poor Early Response to Induction Chemotherapy in Childhood Acute Lymphoblastic Leukemia

  • Bhatia, Prateek;Masih, Shet;Varma, Neelam;Bansal, Deepak;Trehan, Amita
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6663-6668
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    • 2015
  • Background: Treatment failure in leukemia is due to either pharmacokinetic resistance or cell resistance to drugs. Materials and Methods: Gene expression of multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and low resistance protein (LRP) was assessed in 45 pediatric ALL cases and 7 healthy controls by real time PCR. The expression was scored as negative, weak, moderate and strong. Results: The male female ratio of cases was 2.75:1 and the mean age was 5.2 years. Some 26/45 (58%) were in standard risk, 17/45(38%) intermediate and 2/45 (4%) in high risk categorie, 42/45 (93%) being B-ALL and recurrent translocations being noted in 5/45 (11.0%). Rapid early response (RER) at day 14 was seen in 37/45 (82.3%) and slow early response (SER) in 8/45 (17.7%) cases. Positive expression of MDR-1, LRP and MRP was noted in 14/45 (31%), 15/45 (33%) and 27/45 (60%) cases and strong expression in 3/14 (21%), 11/27 (40.7%) and 8/15 (53.3%) cases respectively. Dual or more gene positivity was noted in 17/45 (38%) cases. 46.5 % (7/15) of LRP positive cases at day 14 were in RER as compared to 100% (30/30) of LRP negative cases (p<0.05). All 8 (100%) LRP positive cases in SER had strong LRP expression (p=<0.05). Moreover, only 53.3% of LRP positive cases were in haematological remission at day 30 as compared to 100% of LRP negative cases (p=<0.05). Conclusions: Our study indicated that increased LRP expression at diagnosis in pediatric ALL predicts poor response to early treatment and hence can be used as a prognostic marker. However, larger prospective studies with longer follow up are needed, to understand the clinical relevance of drug resistance proteins.

Deterioration Diagnosis of Surface and Coating Layer for Maintenance Managements of the Membrane Structure (막구조 건축물의 유지관리를 위한 표면 및 코팅층의 열화 진단)

  • Kang, Joo-Won;Lee, Seung-Jae
    • Journal of Korean Association for Spatial Structures
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    • v.11 no.1
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    • pp.97-104
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    • 2011
  • This paper contains of descriptions of deterioration diagnosis of the surface and a coating layer for maintenance managements of large spatial structures with membrane structure. Membrane is a roofing material of the structures that its performance of durability including its performance of chemical resistance and corrosive resistance is considered to be highly important. In general, the items of diagnosis for maintenance managements such as membrane extensively include the diagnosis of deterioration of the membrane surface, of a coating layer of membrane, the diagnosis of deterioration between a coating layer and fiber, of overall surface of membrane, of the class of ropes, of reinforced belts, and of the cover of rubber. The object of this study that needs maintenance managements of the membrane with PVC and FIFE which are commonly used and shows the diagnosis results of deterioration of the surface and a coating layer.

On-Line Insulation Diagnosis Techniques for Stator Winding of Rotating Machines (회전기 고정자 권선에서의 운전 중 절연열화 진단기법)

  • 윤대희;황돈하;신병철;김용주;이광식
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2000.11a
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    • pp.89-93
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    • 2000
  • Recently many research activities on the diagnosis of stator winding insulation of large rotating machines have been reported. Capacitive couplers are widely used as sensors for on-line partial discharge (PD) measurement of high voltage rotating machines. This paper presents laboratory test to compare Stator Slot Coupler (SSC), Resistance Temperature Detector (RTD), 80 [pF] coupler and 500 [pF] coupler for on-line PD measurement of rotating machines. And a novel on-line monitoring system for an insulation diagnosis is proposed.

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Evaluation of Fracture Detection Function for the Concrete by Self-Diagnosis CPGFRP (자기진단 CPGFRP의 파괴예측기능 평가를 위한 콘크리트 적용실험)

  • Choi, Hyun-Soo;Park, Jin-Sub;Jnng, Min-Soo;Kang, Byeung-Hee
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2003.11a
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    • pp.27-31
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    • 2003
  • To maintain serviceability of concrete structure more than proper it is necessary not only predict service life through periodical monitor but also need monitoring system to recognize optimal time and method for repair. Recently, CPGFRP, replacing some GFRP with CF, is developed and used for monitoring concrete fraction. But dramatic resistance change of CPGFRP is showed below 0.5% strain and it is not small strain in terms of monitoring micro crack in concrete. In other word, monitoring with CF is not suitable in low stress hut hight stress. In this study, we accessed applicable possibility and reliability of CPGFRP composite as monitoring sense that is proved very sensitive to stress through domestic and oversea previous study. CPGFRP composite plays a role in specimen like steel and increases flexural strength. CPGFRP composite shows resistance increasement in micro crack. In particular, CPUFRP is more sensitive than strangage in low stress. Resistance change ratio curve is very similar to strain curve so sensitivity and reliability is very excellent to monitor concrete fracture.

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Evaluation of Fracture Detection Function for the Concrete by Self-Diagnosis CPGFRP (자기진단 CPGFRP의 파괴예측기능 평가를 위한 콘크리트 적용실험)

  • 최현수;박진섭;정민수;강병희
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2003.05a
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    • pp.27-31
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    • 2003
  • To maintain serviceability of concrete structure more than proper it is necessary not only predict service life through periodical monitor but also need monitoring system to recognize optimal time and method for repair. Recently, CPGFRP, replacing some GFRP with CF, is developed and used for monitoring concrete fraction. But dramatic resistance change of CPGFRP is showed below 0.5% strain and it is not small strain in terms of monitoring micro crack in concrete. In other word, monitoring with CF is not suitable in low stress but hight stress. In this study, we accessed applicable possibility and reliability of CPGFRP composite as monitoring sense that is proved very sensitive to stress through domestic and oversea previous study. CPGFRP composite plays a role in specimen like steel and increases flexural strength. CPGFRP composite shows resistance increasement in micro crack. In particular, CPGFRP is more sensitive than strangage in low stress. Resistance change ratio curve is very similar to strain curve so sensitivity and reliability is very excellent to monitor concrete fracture.

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Tracking Performance Test of Polymer Insulator with Salt Solution which is added Surface Active Agent (계면활성제가 첨가된 염수용액에 따른 폴리머 애자의 트래킹 성능 평가)

  • Cho, Han-Goo;Lee, Un-Yong;Han, Dong-Hee;Kang, Sung-Hwa;Choi, In-Hyuk;Lim, Kee-Joe
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.1
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    • pp.62-67
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    • 2005
  • Recently, polymer insulators that are used for high voltage applications have some advantages such as light weight, small size, vandalism resistance, hydrophobicity and easy making process. During outdoor service of polymer insulators, the surface of the insulating material is frequently subjected to moisture and contamination that lead to dry band arcing. Their tracking resistance, erosion resistance, end sealing and shed design are very important because dry band arcing causes degradation of polymer surface. Aging test to estimate life property of polymer insulator is executed through several international standard such as IEC 61109 and CEA tracking wheel test, but is not getting clear conclusion yet. There are two methods in the diagnosis method of polymer insulator such as off-line and on-line. The diagnosis methods in off-line are external condition analysis by the eye, contaminant analysis on surface, surface analysis, pollution withstand voltage test, power frequency flashover voltage test, lightning impulse flashover test, tensile fracture load test and flexural load test. Polymer material is also investigated it's tracking resistance by adding surface active agent in IEC 587. In this paper, the tracking performance of polymer insulator with salt solution which is added surface active agent. The diagnosis of insulator sample has been analyzed by leakage current and visual examination, STRI guide and thermal image camera.