• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.6
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• pp.672-680
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• 2023

Weight is a critical factor in the ship design process given that it has a substantial impact on the hydrodynamic performance of ships. Typically, ships are optimally designed for specific conditions with a fixed draft and displacement. However, in reality, weight and draft can vary within a certain range owing to operational activities, such as fuel consumption, ballast adjustments, and loading conditions . Therefore, we investigated how resistance changes under three different loading conditions, namely overload, design-load, and lightship, for small craft, using both model experiments and numerical simulations. Additionally, we examined the sensitivity of weight changes to resistance to enhance the performance of ships, ultimately reducing power requirements in support of the International Maritime Organization's (IMO) goal of reducing CO2 emissions by 50% by 2050. We found that weight changes have a more significant impact at low Froude Numbers. Operating under overload conditions, which correspond to a 5% increase in draft and an 11.1% increase in displacement, can lead to a relatively substantial increase in total resistance, up to 15.97% and 14.31% in towing tests and CFD simulations, respectively.

• Korean Journal of Biological Psychiatry
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• v.19 no.4
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• pp.187-192
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• 2012

Objectives Although antipsychotic drug clozapine has superior efficacy, this is hampered by metabolic side effects such as weight gain and diabetes. Recent studies demonstrate that clozapine induces insulin resistance. However, the identity and location of insulin resistance induced by clozapine has not been clarified. In this study, the effect of clozapine on central insulin response was investigated in rats. Methods Male Sprague-Dawley rats received intraperitoneal injection of clozapine or vehicle, which was followed by intracerebroventricular injection of insulin or its vehicle. The effects of clozapine on insulin-induced changes in blood glucose level and Akt phosphorylation in hypothalamus were investigated. Results Intraperitoneal injection of clozapine (20 mg/kg) increased blood glucose in rats. Intracerebroventricular injection of insulin reduced blood glucose in rats, which was blunted by pretreatment of clozapine. Accompanied with the antagonistic effect of clozapine to central insulin action in terms of blood glucose, clozapine inhibited the insulin-induced phosphorylation of Akt at Ser473 in rat hypothalamus. Conclusion Administration of clozapine inhibited the central insulin-induced changes in blood glucose and Akt phosphorylation in rat hypothalamus. These findings suggest that hypothalamus could be the site of action for the clozapine-induced insulin resistance.

• International Journal of Highway Engineering
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• v.11 no.2
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• pp.111-120
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• 2009

This paper presents a fundamental findings of the functional and structural performance of the porous asphalt concrete coated with MMA resin. To evaluate the structural performance, cantabro, wheel tracking, moisture sensitivity and indirect tensile fatigue tests are performed. The tests results show that the cantabro loss is reduced three times and fatigue resistance is significantly increased after the specimens are coated with MMA resin. However there are little changes in the rutting and moisture damage resistances before and after the coating. Air voids, permeability and BPT(British Pendulum Test) tests are conducted to study the functional performance. It is observed form the tests that the air voids and permeability are slightly decreased after the coating. However, the changes in the air voids and permeability are negligible. The skid resistance of the coated specimens is lower than reference specimens. However, the skid resistance is maintained beyond the level of the reference specimens when silica sands are chipped on top of the coated surface.

• The Journal of Korean Academy of Prosthodontics
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• v.22 no.1
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• pp.95-108
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• 1984

Even though the tarnishing and corrosion problems characteristic with dental silver-palladium alloy are not yet fully solved, it is recently widely used because of its low cost. However the effects of major alloying elements on the various properties of this system are not fully understood. The object of this research is to clarify the effects of In and Zn additives on the corrosion and tarnishing resistances and precipitation hardening behavior of this sytem, using electrodynamic polarization, immersion, and Vicker's microhardness test and X-ray diffraction and electron probe micro analysis methods. The obtained results were as follows: I. As indium content is increased, both the corrosion resistance in Cl-solution and microhardness are also increased while the tarnishing resistance is decreased. 2. As Zinc content is increased, the corrosion resistance is decreased, but tarnishing resistance is increased 3. At 70Ag-25Pd-2.5Zn-2.5In composition, the precipitation harding behavior was mot significant. The optimum aging temperature was $450^{\circ}C$ and the time was 2 hrs. The resulting specimen of this work carried 180VHN. 4. Under the heat treatment, the changes in the mechanical property are due to the changes in the shape and composition of dendrite matrix, namely, it is because of the precipitation hardening behavior which has been proved by electron probe micro analysis and optical microscopic finding.

• Journal of Microbiology and Biotechnology
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• v.13 no.5
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• pp.751-758
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• 2003

Mutations in the rdxA gene had been reported to be associated with metronidazole resistance in Helicobacter pylori. In this study, sensitivity to metronidazole, RAPD profiles, and DNA sequences of the rdxA gene of 32 local H. pylori isolates were analyzed. Of these, 13 were found to be resistant, while 19 were sensitive to metronidazole. Among the 32 isolates, 10 were paired isolates from the antrum and body of the stomach of individual patients. Interestingly, the RAPD profiles of isolates from individual patients were distinctly different from each other, whereas paired isolates from the same patient were identical regardless of their sensitivities to metronidazole. DNA sequences of the rdxA gene of all 32 isolates showed 95% to 97% homology when compared with the HP0954 locus of H. pylori 26695 genome. From the 19 metronidazole-sensitive strains, 10 (with $MIC{\le}0.5\;\mu\textrm{g}/ml$ metronidazole) were selected and induced to become metronidazole resistant by sequentially passaging through serial 2-fold increasing concentrations of metronidazole. Nine of the 10 induced paired isolates showed mutations in the rdxA sequences which resulted in truncated protein or changes in the translated amino acid sequences. However, the changes did not occur at any specific site in the DNA or amino acid sequences of the rdxA gene of all the isolates analyzed. The results show that the rdxA gene cannot be a definitive marker for metronidazole resistance in H. pylori isolates of an Asian population, and that other factors may contribute to resistance to metronidazole.

• Journal of the Korea Concrete Institute
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• v.18 no.3 s.93
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• pp.439-445
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• 2006

For investigating self-diagnosis applicability, a method based on monitoring the changes in the electrical resistance of hybrid FRP(having electrical property) reinforced concrete has been tested. Then after examining change in the value of electrical resistance of carbon fiber in CFRP(non-hybrid type), CFGFRP and CFAFRP(hybrid type) before and after the occurrence of cracks and fracture in non-hybrid and hybrid FRP reinforced concrete at each flexural weight-stage, the correlations of each factors(the changes in electrical resistance and load as a function of strain, deflection) were analyzed. As the results, it is clarified that when the carbon fiber tows fracture, the electrical resistance of it increase largely, and afterwards hybrid FRP composites can be resist the load due to the presence of the reinforced fiber, for example, glass fiber or aramid fiber tows. Therefore, it can be recognized that hybrid FRP(including carbon fiber) reinforcing bar could be applied for self-diagnosis of fracture in reinforced FRP concrete fracture.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2002.10a
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• pp.212-215
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• 2002

Interfacial evaluation and damage sensing of the carbon fiber/epoxy-amine terminated (AT)-polyetherimide (PEI) composites were performed using micromechanical test and electrical resistance measurement. As AT-PEI content increased, the fracture toughness of epoxy-AT-PEI matrix increased, and thus their interfacial shear strength (IFSS) was improved due to the improved toughness. After curing process, the changes in electrical resistance (ΔR) with increasing AT-PEI contents increased gradually because of the changes in thermal expansion coefficient (TEC) and thermal shrinkage of matrix. Matrix fracture toughness was correlated to the IFSS, residual stress and electrical resistance. The results obtained from the electrical resistance measurement during curing process, reversible stress/strain, and durability test were consistent with modified matrix toughness properties.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.3
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• pp.101-108
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• 2015

PURPOSE: This study researched the effects of the changes of elbow joint angle and of arm position in PNF pattern on muscle activation of the contralateral shoulder muscles while performing PNF pattern exercise. METHODS: The research subjects were 16 male physical therapists who had no neuromuscular or neurological disorders. To measure the muscle activation of the contralateral shoulder muscles, EMG electrodes were attached to the muscle valley of the middle and posterior areas of the deltoid and triceps muscles of the arm. Muscle activation while performing the ulnar thrust PNF pattern exercise was measured with the elbow joint positioned at angles of $30^{\circ}$, $45^{\circ}$, and $60^{\circ}$. Resistance points were at the initial, middle, and end ranges of PNF pattern exercise. RESULTS: Muscle activation of the middle and posterior portions of the deltoid muscle increased significantly according to the changes of elbow joint angle. In each resistance point the middle range was significantly higher than at other points. A significant difference on muscle activation was demonstrated throughout each range depending on the type of muscle. Muscle activation of the middle and posterior portions of the deltoid muscle was higher than muscle activation of the triceps. CONCLUSION: The results of this study demonstrate that the PNF pattern exercising method used in this study is a selective exercising method focusing on the deltoid muscle over the triceps muscle. In order to increase the muscle strength to the maximum level, it is necessary to provide the maximum level of resistance in the middle range of the elbow joint.

• Journal of Ocean Engineering and Technology
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• v.29 no.6
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• pp.418-426
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• 2015

Recently, shipping operators have been making efforts to reduce the fuel cost in various ways, such as trim optimization and bulb re-design. Furthermore, IMO restricts the hydro-dioxide emissions to the environment based on the EEDI (Energy Efficiency Design Index), EEOI (Energy Efficiency Operational Indicator), and SEEMP (Ship Energy Efficiency Management Plan). In particular, ship speed is one of the most important factors for calculating the EEDI, which is based on methods suggested by ITTC (International Towing Tank Conference) or ISO (International Standardization Organization). Many shipbuilding companies in Korea have carried out speed trials around the Korea Straits. However, the conditions for these speed trials have not been exactly the same as those for model tests. Therefore, a ship’s speed is corrected by measured environmental data such as the seawater temperature, density, wind, waves, swell, drift, and rudder angle to match the conditions of the model tests. In this study, fundamental research was performed to evaluate the ship resistance performance due to changes in the water temperature and salinity, comparing the ISO method and numerical simulation. A numerical simulation of a KCS (KRISO Container ship) with a free-surface was performed using the commercial software Star-CCM+ under three conditions that were assumed based on the water temperature and salinity data in the Korea Straits. In the simulation results, the resistance increased under low water temperature & high salinity conditions, and it decreased under high water temperature & low salinity conditions. In addition, the ISO method showed the same result as the simulation.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.1
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• pp.137-148
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• 2011

Objectives : This study was to investigate the visual bio-feedback training for 5 weeks on balance and postural control for patients with stroke. Methods : The 26 subjects were randomly selected from the patients of the E hospital in the S city who met the study conditions. They were divided into a visual bio-feedback training group of 13 patients and a self-resistance exercise group of 13 patients. The visual bio-feedback training group received visual bio-feedback and general physiotherapy for five weeks and the self-resistance exercise group received cycling and general physiotherapy for the same period. The subjects were measured and compared for stability index, weight distribution index, fall down index, functional reach test and timed up and go test before and after the program. Results : The visual bio-feedback training group showed significant changes after the experiment in stability index, weight distribution index, functional reach test and timed up and go test(p<0.05), and the self-resistance exercise group also showed significant differences(p<0.05). The changes between prior to and after the experiment show that the visual bio-feedback training group had more significant effects than the self-resistance exercise group(p<0.05). Conclusions : The visual bio-feedback training for five weeks had effects in the improvement of the balance and posture control of stroke patients. Based on these results, more effective training programs should be developed and propagated.