• Title/Summary/Keyword: residual disease

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Bayesian Modeling of Mortality Rates for Colon Cancer

  • Kim Hyun-Joong
    • Communications for Statistical Applications and Methods
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    • v.13 no.1
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    • pp.177-190
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    • 2006
  • The aim of this study is to propose a Bayesian model for fitting mortality rate of colon cancer. For the analysis of mortality rate of a disease, factors such as age classes of population and spatial characteristics of the location are very important. The model proposed in this study allows the age class to be a random effect in addition to its conventional role as the covariate of a linear regression, while the spatial factor being a random effect. The model is fitted using Metropolis-Hastings algorithm. Posterior expected predictive deviances, standardized residuals, and residual plots are used for comparison of models. It is found that the proposed model has smaller residuals and better predictive accuracy. Lastly, we described patterns in disease maps for colon cancer.

A Study on Effect of Residual Stress on Stress Distribution of Arterial Walls Under High Blood Pressure (잔류응력 효과를 고려한 고혈압 상태에 있는 혈관벽 내의 응력분포에 대한 연구)

  • Choi, Jae-Woo;Choi, Deok-Kee
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.11
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    • pp.1219-1227
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    • 2011
  • Due to recent changes in living conditions, people who suffer from vascular disease have been increasing. As a result, several kinds of procedures to treat diseases of the blood vessels are being carried out and the epidemiological analysis and interpretation is needed. In this paper, the mechanical behavior of blood vessels based on hyperelastic model were evaluated. The stress distributions in the arterial walls subjected to both normal blood pressure and high blood pressure are studied along with different opening angles representing as the effect of the residual stress. As a result, when applied to residual stress effects in blood vessels to act maximum stress compared to as the absence of residual stress effect about 50% stresses can be reduced. When high blood pressure was the normal blood pressure acting on the blood vessel wall that twice stress can be confirmed.

Malaria Cell Image Recognition Based On VGG19 Using Transfer Learning (전이 학습을 이용한 VGG19 기반 말라리아셀 이미지 인식)

  • Peng, Xiangshen;Kim, Kangchul
    • The Journal of the Korea institute of electronic communication sciences
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    • v.17 no.3
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    • pp.483-490
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    • 2022
  • Malaria is a disease caused by a parasite and it is prevalent in all over the world. The usual method used to recognize malaria cells is a thick and thin blood smears examination methods, but this method requires a lot of manual calculation, so the efficiency and accuracy are very low as well as the lack of pathologists in impoverished country has led to high malaria mortality rates. In this paper, a malaria cell image recognition model using transfer learning is proposed, which consists in the feature extractor, the residual structure and the fully connected layers. When the pre-training parameters of the VGG-19 model are imported to the proposed model, the parameters of some convolutional layers model are frozen and the fine-tuning method is used to fit the data for the model. Also we implement another malaria cell recognition model without residual structure to compare with the proposed model. The simulation results shows that the model using the residual structure gets better performance than the other model without residual structure and the proposed model has the best accuracy of 97.33% compared to other recent papers.

Probable Nonconvulsive Status Epilepticus after Drainage of a Chronic Subdural Hematoma in a Patient with Moyamoya Disease

  • Lee, Chang-Sub;Huh, Ji-Soon;Sim, Ki-Bum;Choi, Jay-Chol
    • Journal of Korean Neurosurgical Society
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    • v.41 no.6
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    • pp.414-417
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    • 2007
  • A 52-year-old woman with hypertension and moyamoya disease presented with chronic subdural hematoma [CSDH]. The presumed cause of bleeding was ascribed to administrated antiplatelet agents. She responded slowy and clumsily to verbal commands and had right arm weakness. After surgery, her clinical condition improved. But two days after surgery, her symptoms became aggravated and a convulsive seizure was noted within 24 hours. Brain magnetic resonance imaging showed no organic lesion except a small amount of residual CSDH. In addition, there was no laboratory evidence of metabolic brain disease. Moreover, after the administration of an antiepileptic drug [phenytoin], her manifestations disappeared. Therefore, the authors presume that her symptoms were resulted from nonconvulsive status epilepticus [NCSE], despite a lack of ictal period electroencephalographic findings. The authors were unable to find a single case report on postoperative NCSE in Korea. Therefore, the authors report this case of nonconvulsive status epilepticus after drainage of a CSDH in a patient with moyamoya disease.

Selection of Reference Equations for Lung Volumes and Diffusing Capacity in Korea (우리나라 성인 폐용적 및 폐확산능 정상예측식의 선정)

  • Song, Eun Hee;Oh, Yeon Mok;Hong, Sang Bum;Shim, Tae Sun;Lim, Chae Man;Lee, Sang Do;Koh, Youn Suck;Kim, Woo Sung;Kim, Dong Soon;Kim, Won Dong;Kim, Tae Hyung
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.3
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    • pp.218-226
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    • 2006
  • Background: The lung volume and diffusing capacity are influenced by ethnicity. However, there are no equations for predicting the normal lung volume in the adult Korean population, and there is only one equation for diffusing capacity. The aim of this study is to select the most suitable reference equation for the Korean population. Method: 30 men and 33 women at Hanyang University Guri Hospital, and 27 men and 34 women at Asan Medical Center in healthy nonsmoking adults were enrolled in this study. The subject's age, gender, height, weight, lung volume by plethysmography, and diffusing capacity by a single breathing method were obtained. The most suitable equation with the lowest sum of residuals between the observed and predicted values for lung volume and diffusing capacity was selected. Result: At Hanyang University Guri Hospital, the equations with the lowest sum of residuals in the total lung capacity were ECSC's equation in males (sum of residual: 0.04 L) and Crapo/Morris's equation (-1.04) in women. At the Asan Medical Center, the equations with the lowest sum of residuals in the total lung capacity were Goldman/Becklake's equation in males (sum of residual: -2.35) and the ECSC's equation -4.49) in women. The equations with the lowest sum of residuals in the Diffusing capacity were Roca's equation in males (sum of residual: -13.66 ml/min/mmHg) and Park's in women (25.08) in Hanyang University Guri hospital and Park's equation in all cases in the Asan Medical Center (male: -1.65, female: -6.46). Conclusions: Until a reference equstion can be made for healthy Koreans by sampling, ECSC's equation can be used for estimating the lung volume and Park's can be used for estimating the diffusing capacity.

Monitoring of Antibiotics in the Soil and Sediment Near at the Animal Feeding Operation and Wastewater Treatment Plant

  • Kim, Hye Ri;Park, Saet Byul;Kim, Sung Chul
    • Korean Journal of Soil Science and Fertilizer
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    • v.50 no.4
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    • pp.285-292
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    • 2017
  • Antibiotics have been used for treating human and animal disease and enhancing growth of cattle, swine, and poultries. However, overused antibiotics can be released into the environment and produce antibiotic resistance genes (ARGs) in the environment. Main objective of this research was to monitor residual of antibiotics in solid matrix such as manure, wastewater sludge, soil and sediment. Total of six antibiotics, Chlortetracycline (CTC), Oxytetracycline (OTC), Tetracycline (TC), Sulfamethazine (SMT), Sulfamethoxazole (SMX), Sulfathiazole (STZ), used for both human and animal was monitored. Result showed that the detection frequency of 6 antibiotics was ordered SMT (100%) > TC = CTC (75%) > OTC (38%) > STZ (13%) > SMZ (0%) and the highest concentration ($309.83{\mu}g\;kg^{-1}$, SMT) was observed in manure. Comparing residual concentration of antibiotics (TC, CTC, and OTC) in soil and sediment, higher concentration was observed in sediment indicating that dissolved forms of antibiotics are released into river and sorbed into sediment particle. In conclusion, monitoring for residual of antibiotics in the environment is necessary and more research should be conducted to verify the source of antibiotic release.

The Role of FDG PET in Malignant Lymphoma (악성 림프종에서 FDG PET의 역할)

  • Yun, Mi-Jin
    • The Korean Journal of Nuclear Medicine
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    • v.36 no.1
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    • pp.53-63
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    • 2002
  • FDG PET is a functional imaging modality whose ability to detect lesions is directly based on a change of the glycolytic metabolism of targeted tissues, may be advantageous over other techniques. Combined with excellent image qualify, high spatial resolution, and whole body imaging capability, it has become popular as a new approach in the evaluation of patients with various malignancies. Initial staging of nodal and extranodal lymphoma using FDG PET has been proven to be at least equal or superior to conventional imaging modalities. For the assessment of treatment responsiveness, FDG PET has a major impact on the management of patients in differentiating residual lymphoma from treatment related benign changes. Residual FDG uptake after the completion of chemotherapy is a good predictor of early relapse. However, it seems that the absence of FDG uptake in tumor mass may not exclude minimal residual disease causing later relapse. In the early evaluation of treatment response only after a few cycles of chemotherapy, FDG PET may have a promising role in identifying non-responders who could benefit from a different treatment strategy. At present, FDG PET appears to be the cost-effective, diagnostic modality of choice in the management of lymphoma patients. The role of FDG PET based-systems in terms of affecting long-term prognosis and survival benefit should be further elucidated in future prospective studios.

THE STUDY ABOUT THE DIAGNOSTIC PARAMETERS OF OPSTEOPOROSIS ON PANORAMIC RADIOGRAPH (골다공증의 파노라마방사선사진상 진단학적 매개변수에 관한 연구)

  • Lee, Yong Gyoo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.20 no.4
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    • pp.279-283
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    • 1998
  • The osteoporosis is a disease that represents a reduction in the volume of bony tissue relative to whole bone volume. And mandible also may be affected. Such porotic mandible may influence the result of the surgery like dental implant surgery relating mandible. So, the author examed the panoramic view of 89 persons for finding the possibility of useful diagnostic parameters of osteoporosis. To know the correlationship between the condition of vertebra and mandible, bone marrow density of lumbar spine from 2nd to 4th, and the number of residual tooth, panoramic mandibular index (PMI), angular cortical bone thickness (ACT) and ramus cortical bone thickness (RCT) were compared. The result is that PMI and ACT have similar relative weak linear correlationship, RCT have very weak linear correlationship, the number of residual tooth have not linear correlationship.

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Anesthetic management in corticobasal degeneration with central sleep apnea: A case report

  • Shionoya, Yoshiki;Nakamura, Kiminari;Sunada, Katsuhisa
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.19 no.4
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    • pp.235-238
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    • 2019
  • Corticobasal degeneration (CBD) is a rare neurodegenerative disease characterized by dystonia, cognitive deficits, and an asymmetric akinetic-rigid syndrome. Little information is available regarding anesthetic management for CBD patients. Our patient was a 55-year-old man with CBD complicated by central sleep apnea (CSA). Due to the risk of perioperative breathing instability associated with anesthetic use, a laryngeal mask airway was used during anesthesia with propofol. Spontaneous respiration was stable under general anesthesia. However, respiratory depression occurred following surgery, necessitating insertion of a nasopharyngeal airway. Since no respiratory depression had occurred during maintenance of the airway using the laryngeal mask, we suspected an upper airway obstruction caused by displacement of the tongue due to residual propofol. Residual anesthetics may cause postoperative respiratory depression in patients with CBD. Therefore, continuous postoperative monitoring of $SpO_2$ and preparations to support postoperative ventilation are necessary.

The Residues of Enrofloxacin in Cultured Paralichthys olivaceus (양식산 넙치에서 Enrofloxacin의 잔류)

  • Seo, Jung Soo;Jeon, Eun Ji;Lee, Eun Hye;Jung, Sung Hee;Park, Myoung Ae;Jee, Bo Young;Kim, Na Young
    • Journal of fish pathology
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    • v.26 no.1
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    • pp.45-50
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    • 2013
  • Enrofloxacin is one of the normally used flouroquinolones in mammalian and fish but its withdrawal time and studies were remain obscure. The residual contents of enrofloxacin in fish muscle were analyzed by using HPLC-FLD. More than 0.1 mg/kg of ENR was detected in muscle tissues and the residues were found over 1 year after treatment. The concentration of ENR in Paralichthys olivaceus was not affected by water temperature and lasted for an extended amount of time. The spike recoveries of ENR in the muscle tissue ranged from 78% to 85%. From this results, we need the prescription by veterinarian or aquatic organism disease inspector in ENR usage to assure safety of fish. Future research is required to determine the recommendation dose of ENR for side effects and safety.