• 동의생리병리학회지
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• 제25권2호
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• pp.326-333
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• 2011

This study was to develop an issue-centered small-group competing-debate program for the Introduction to Traditional Korean Medicine curriculum in School of Korean Medicine, Pusan National University. This debate program has student-, process- and depth-focused characteristics with critical-thinking perspectives. We employed random assignment of the position, submission of the presentation data prior to the debate, and individual result report to assess debate quality and participation of the students. This program was effective educational program for the understanding of traditional Korean medicine-related subjects. 56.7% of the students showed "Yes (>7 out of 10)" to the achievements of the program objectives, and 62.2% reported "much helpful (>7 out of 10)" to the usefulness of this program. We also found that this debate program would be specifically useful for critical reviewing of subjects which students have known superficially. This study will contribute to the development and improvement of efficacious educational curriculum for Korean Medicine by providing practical reference and template with self-directed group debate program.

• 공학교육연구
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• 제14권2호
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• pp.13-20
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• 2011

본 연구의 목적은 한국과 미국의 프로그램 학습성과 평가체계 사례를 비교 분석함으로써 프로그램 학습성과 평가체계 개선을 위한 시사점을 제공하는 것이다. 연구의 목적을 달성하기 위해 사례연구방법이 적용되었다. 미국에서 공학교육인증을 우수하게 수행하고 있는 5개 대학 프로그램과 한국에서 공학교육혁신센터를 주축으로 연구를 수행하여 프로그램 학습성과 평가체계를 개선한 3개 대학을 선정하여 각각의 프로그램 학습성과 평가체계 사례를 분석하였다. 분석 결과 각 프로그램에서 설정한 학습성과, 학습성과를 평가하는 수준, 학생의 학습성과 달성도 평가 방법, 분석 및 개선 실적 측면에서 차이가 있는 것으로 나타났다. 연구 결과에 기반하여 프로그램 학습성과 평가체계 개선을 위해서는 학생의 학습성과 달성도 평가방법에 대한 관심보다는 프로그램의 특성이 반영된 학습성과 설정, 학습성과 평가결과 분석 및 개선에 대한 보다 구체적인 계획 수립, 수집된 자료에 근거하여 교육과정을 지속적으로 개선하는 데 보다 노력을 기울일 것을 제안하였다.

• 한국산림과학회지
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• 제101권3호
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• pp.469-479
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• 2012

본 연구의 목적은 숲길프로그램에 대한 이용객의 선호와 이용 행태, 숲길에 따른 이용특성을 파악하는 것이다. 숲길프로그램 참여의사, 선호하는 산림휴양활동, 프로그램 내용과 실질적인 프로그램 운영방식에 대한 이용객의 요구를 살펴보았다. 숲길프로그램이 필요하다는 응답이 높게 나타났고 산림휴양활동, 숲길프로그램 내용, 운영방식은 이용대상, 이용행태, 숲길에 따라 차이를 보였다. 20대는 활동성이 높은 자연체험 프로그램, 중 노년층은 건강 프로그램을 선호하였다. 프로그램 운영은 현장에서 진행하는 정기 프로그램을 선호하였고, 운영시간은 1~3시간이 적절한 것으로 나타났다. 숲길별로 살펴보면 북한산 둘레길은 산림치유 등 건강프로그램 위주의 1~2시간 진행되는 정기 프로그램이 적합할 것으로 생각되며 울진숲길은 기존의 가이드방식에 자연감수성을 키울 수 있는 다양한 체험활동의 도입이 필요할 것으로 보인다. 지리산 둘레길은 젊은 층의 이용이 많고 다른 숲길에 비해 트레킹을 중심으로한 프로그램개발이 필요하다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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• pp.899-902
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• 2004

The molecular reorientations and surface morphologies of rubbed films formed from atactic polystyrene (PS) samples with various molecular weights were investigated in detail. Previously unknown surface topography features were newly discovered in rubbed films, depending on molecular weights: submicroscale groove-like meandering structures composed of fine-grooves like pebbles in tens nanometers are present, oriented perpendicular to the rubbing direction. The vinyl main chains, however, were preferentially reoriented along the rubbing direction and the planes of the phenyl side groups were preferentially reoriented perpendicular to the rubbing direction with para-directions that were positioned nearly normal to the film plane. Nematic liquid crystal (LC) molecules were found to always align on the rubbed PS surfaces along the orientation direction of the submicroscale grooves generated by rubbing.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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• pp.894-896
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• 2003

Koh Chang Island is located near the east border of Thailand. The government of Thailand promotes the island as a model of eco-tourism spots. The Island undeveloped until recent years, is expected to change to major tourist attraction. 'Digital Koh Chang project' has thus. The main objective of this project is to monitor the environment and land use status of the island and to support its sound development. In March 2003, a field survey of this project was planned and field data were collected using both airborne and ground platforms and an ocean vessel. These data were combined with satellite data in the laboratory. This presentation is all balloon-born system field operation. A 5-meter length balloon filled with Helium gas was used, whose payload consisted of two RGB standard color digital still cameras, two directional rotating servo motors, a camera mount cradle as well as signal transmitting and receiving components. A series of aerial high-resolution digital images were rather easily obtained using this inexpensive system, making it possible to monitor intended landscape features in a specific field. Design of simple, low-cost and easily transportable flying platforms and local field surveys using them are useful for getting local ground truth data to calibrate satellite or airborne-based RS data. The design analysis to upgrade the system is further investigated.

• Molecules and Cells
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• 제42권11호
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• pp.810-819
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• 2019

For physiological or pathological understanding of bone disease caused by abnormal behavior of osteoclasts (OCs), functional studies of molecules that regulate the generation and action of OCs are required. In a microarray approach, we found the suppression of tumorigenicity 5 (ST5) gene is upregulated by receptor activator of nuclear $factor-{\kappa}B$ ligand (RANKL), the OC differentiation factor. Although the roles of ST5 in cancer and ${\beta}-cells$ have been reported, the function of ST5 in bone cells has not yet been investigated. Knockdown of ST5 by siRNA reduced OC differentiation from primary precursors. Moreover, ST5 downregulation decreased expression of NFATc1, a key transcription factor for osteoclastogenesis. In contrast, overexpression of ST5 resulted in the opposite phenotype of ST5 knockdown. In immunocytochemistry experiments, the ST5 protein is colocalized with Src in RANKL-committed cells. In addition, ST5 enhanced activation of Src and Syk, a Src substrate, in response to RANKL. ST5 reduction caused a decrease in RANKL-evoked calcium oscillation and inhibited translocation of NFATc1 into the nucleus. Taken together, these findings provide the first evidence of ST5 involvement in positive regulation of osteoclastogenesis via Src/Syk/calcium signaling.

• PNF and Movement
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• 제17권1호
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• pp.69-79
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• 2019

Purpose: This study aims to investigate the effects of a group computerization cognitive rehabilitation program on cognitive function in patients with cognitive impairment. Methods: The subjects of this study comprised 34 patients with cognitive impairment (15 males and 19 females) who were randomized into two groups. The experimental group (n = 17) were trained with the group computerization cognitive rehabilitation program, while the control group (n=17) received traditional cognitive therapy. The interventions for both groups were performed for 1 hour per day, once a week for 12 weeks. The cognitive functions of the subjects before and after the experiment were measured using the Korean mini-mental state examination (K-MMSE), global deterioration scale (GDS), clinical dementia rating (CDR), and Lowenstein occupational therapy cognitive assessment (LOTCA). A paired t-test was conducted to examine the intragroup differences before and after the experiment, and ANCOVA was performed to check intergroup differences. Results: The intragroup comparison results showed that the cognitive function of the group that were trained with the group computerization cognitive rehabilitation program improved after the experiment more than for the group that received traditional cognitive therapy. The intergroup comparison results showed significant differences in orientation, visual perception, and visuomotor organization between the two groups. Conclusion: The results of this study confirmed that the group computerization cognitive rehabilitation program was more effective in improving cognitive function than the traditional cognitive therapy in patients with cognitive impairment. Based on the results of this study, the group computerization cognitive rehabilitation program can be used as an effective intervention method for patients with cognitive impairment.

• Molecules and Cells
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• 제45권10호
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• pp.749-760
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• 2022

Osteoclast generation from monocyte/macrophage lineage precursor cells needs to be tightly regulated to maintain bone homeostasis and is frequently over-activated in inflammatory conditions. PARK2, a protein associated with Parkinson's disease, plays an important role in mitophagy via its ubiquitin ligase function. In this study, we investigated whether PARK2 is involved in osteoclastogenesis. PARK2 expression was found to be increased during the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation. PARK2 gene silencing with siRNA significantly reduced osteoclastogenesis induced by RANKL, LPS (lipopolysaccharide), TNFα (tumor necrosis factor α), and IL-1β (interleukin-1β). On the other hand, overexpression of PARK2 promoted osteoclastogenesis. This regulation of osteoclastogenesis by PARK2 was mediated by IKK (inhibitory κB kinase) and NF-κB activation while MAPK (mitogen-activated protein kinases) activation was not involved. Additionally, administration of PARK2 siRNA significantly reduced osteoclastogenesis and bone loss in an in vivo model of inflammatory bone erosion. Taken together, this study establishes a novel role for PARK2 as a positive regulator in osteoclast differentiation and inflammatory bone destruction.

• 대한간호학회지
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• 제44권6호
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• pp.697-707
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• 2014

Purpose: The purposes of this study was to develop a comprehensive community-based fall prevention program and to test the effects of the program on the muscle strength, postural balance and fall efficacy for elderly people. Methods: The design of this study was a nonequivalent control group pretest-posttest design. There were 28 participants in the experimental group and 29 in the control group. The program consisted of balance exercises, elastic resistance exercises and prevention education. The program was provided five times a week for 8 weeks and each session lasted 90 minutes. Data were analyzed using ${\chi}^2$-test, independent t-test and paired t-test using the SPSS program. Results: Muscle strength of the lower extremities, postural balance and fall efficacy scores significantly improved in the experimental group compared to the control group. Conclusion: These results suggest that this program can improve lower extremity muscle strength, postural balance and fall efficacy in elders. Therefore, this program is recommended for use in fall prevention programs for elders living in the community.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.127-133
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• 2007

Objectives : This study were aimed to estimate the needs for clinical research educational program development focused on oriental medicine. Methods : Department Medical Research of Korea Institute of Oriental Medicine surveyed 204 certified subjects in total by using web-based questionnaires through e-mail from Jan. 17th to Jan. 31th, 2007. Reply from 62 on-line correspondents were collected and statistically analyzed. Results : The number of clinical trial involving oriental medicine continues to increase. According to the survey, many Issues were raised as problems such as difficulty of recruitment, lack of fund and lack of stepped program. Emphasized issues were clinical research methodologies, development of protocols and case report form (CRF), and Regulations including Institutional Review Boards (IRBs) in these three consecutive education training program. Conclusion : The results of this study may contribute to the development of an educational program for oriental medicine, a program that should be taken into consideration for developing practical items, such as, problem-based learnings which reflects participants' actual needs in their works. Also this report be used for future strategy plans and execution of training program for oriental medical clinical trial.