• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.2
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• pp.326-333
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• 2011

This study was to develop an issue-centered small-group competing-debate program for the Introduction to Traditional Korean Medicine curriculum in School of Korean Medicine, Pusan National University. This debate program has student-, process- and depth-focused characteristics with critical-thinking perspectives. We employed random assignment of the position, submission of the presentation data prior to the debate, and individual result report to assess debate quality and participation of the students. This program was effective educational program for the understanding of traditional Korean medicine-related subjects. 56.7% of the students showed "Yes (>7 out of 10)" to the achievements of the program objectives, and 62.2% reported "much helpful (>7 out of 10)" to the usefulness of this program. We also found that this debate program would be specifically useful for critical reviewing of subjects which students have known superficially. This study will contribute to the development and improvement of efficacious educational curriculum for Korean Medicine by providing practical reference and template with self-directed group debate program.

• Journal of Engineering Education Research
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• v.14 no.2
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• pp.13-20
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• 2011

This study aimed to seek the ways of improving program outcomes assessment systems for engineering education accreditation of South Korea through performing comparative analysis on those of the United States. Case-study research method was implemented to achieve the research goal. Five university programs, which have been well recognized as good practices in engineering education accreditation in the United States, were selected and analyzed. In addition, those of three universities in South Korea were chosen for comparative analysis, which were reformed by university affiliated Engineering Education Innovative Centers. The analysis results indicated that there were differences in each program's program outcomes, assessment level of program outcomes, evaluation methods on program outcomes achievement, and analysis and improvement records. It was drawn up that the evaluation methods on program outcomes achievement should be paid full attention. For better program outcomes assessment system, however, the followings are in more attention. Firstly, to establish program outcomes reflecting program goal. Secondly, to set up the detailed plans for analysis and quality improvement on program outcomes. Thirdly, to keep continuing efforts on curriculum update.

• Journal of Korean Society of Forest Science
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• v.101 no.3
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• pp.469-479
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• 2012

Trail is a main infrastructure for various forest recreational activities. In this study, the recreational supply (trail) and demand (trail program according to visitor characteristics, preferred forest activities) were studied. Through the application of a multiple correspondence analysis and cross tabulation analysis, 3 trails (Bukhansan trail, Uljin trail, Jirisan trail) were identified. On this study, visitor demands for trail program participation, preferred forest recreational activities, program contents and program operations. Visitors expressed positive attitude toward trail program participating and showed characteristics with the differences. Young visitors preferred active experience program and middle aged visitors more liked health program such as forest therapy. On site program and self guided interpretation were preferred for program operation. In Bukhansan trail, continuous health program (1~2 hours) would be proper and it needs to adapt various nature activities in the Uljin trail. For the Jirisan trail, self guided program would be developed in many ways.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.899-902
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• 2004

The molecular reorientations and surface morphologies of rubbed films formed from atactic polystyrene (PS) samples with various molecular weights were investigated in detail. Previously unknown surface topography features were newly discovered in rubbed films, depending on molecular weights: submicroscale groove-like meandering structures composed of fine-grooves like pebbles in tens nanometers are present, oriented perpendicular to the rubbing direction. The vinyl main chains, however, were preferentially reoriented along the rubbing direction and the planes of the phenyl side groups were preferentially reoriented perpendicular to the rubbing direction with para-directions that were positioned nearly normal to the film plane. Nematic liquid crystal (LC) molecules were found to always align on the rubbed PS surfaces along the orientation direction of the submicroscale grooves generated by rubbing.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.894-896
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• 2003

Koh Chang Island is located near the east border of Thailand. The government of Thailand promotes the island as a model of eco-tourism spots. The Island undeveloped until recent years, is expected to change to major tourist attraction. 'Digital Koh Chang project' has thus. The main objective of this project is to monitor the environment and land use status of the island and to support its sound development. In March 2003, a field survey of this project was planned and field data were collected using both airborne and ground platforms and an ocean vessel. These data were combined with satellite data in the laboratory. This presentation is all balloon-born system field operation. A 5-meter length balloon filled with Helium gas was used, whose payload consisted of two RGB standard color digital still cameras, two directional rotating servo motors, a camera mount cradle as well as signal transmitting and receiving components. A series of aerial high-resolution digital images were rather easily obtained using this inexpensive system, making it possible to monitor intended landscape features in a specific field. Design of simple, low-cost and easily transportable flying platforms and local field surveys using them are useful for getting local ground truth data to calibrate satellite or airborne-based RS data. The design analysis to upgrade the system is further investigated.

• Molecules and Cells
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• v.42 no.11
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• pp.810-819
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• 2019

For physiological or pathological understanding of bone disease caused by abnormal behavior of osteoclasts (OCs), functional studies of molecules that regulate the generation and action of OCs are required. In a microarray approach, we found the suppression of tumorigenicity 5 (ST5) gene is upregulated by receptor activator of nuclear $factor-{\kappa}B$ ligand (RANKL), the OC differentiation factor. Although the roles of ST5 in cancer and ${\beta}-cells$ have been reported, the function of ST5 in bone cells has not yet been investigated. Knockdown of ST5 by siRNA reduced OC differentiation from primary precursors. Moreover, ST5 downregulation decreased expression of NFATc1, a key transcription factor for osteoclastogenesis. In contrast, overexpression of ST5 resulted in the opposite phenotype of ST5 knockdown. In immunocytochemistry experiments, the ST5 protein is colocalized with Src in RANKL-committed cells. In addition, ST5 enhanced activation of Src and Syk, a Src substrate, in response to RANKL. ST5 reduction caused a decrease in RANKL-evoked calcium oscillation and inhibited translocation of NFATc1 into the nucleus. Taken together, these findings provide the first evidence of ST5 involvement in positive regulation of osteoclastogenesis via Src/Syk/calcium signaling.

• PNF and Movement
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• v.17 no.1
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• pp.69-79
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• 2019

Purpose: This study aims to investigate the effects of a group computerization cognitive rehabilitation program on cognitive function in patients with cognitive impairment. Methods: The subjects of this study comprised 34 patients with cognitive impairment (15 males and 19 females) who were randomized into two groups. The experimental group (n = 17) were trained with the group computerization cognitive rehabilitation program, while the control group (n=17) received traditional cognitive therapy. The interventions for both groups were performed for 1 hour per day, once a week for 12 weeks. The cognitive functions of the subjects before and after the experiment were measured using the Korean mini-mental state examination (K-MMSE), global deterioration scale (GDS), clinical dementia rating (CDR), and Lowenstein occupational therapy cognitive assessment (LOTCA). A paired t-test was conducted to examine the intragroup differences before and after the experiment, and ANCOVA was performed to check intergroup differences. Results: The intragroup comparison results showed that the cognitive function of the group that were trained with the group computerization cognitive rehabilitation program improved after the experiment more than for the group that received traditional cognitive therapy. The intergroup comparison results showed significant differences in orientation, visual perception, and visuomotor organization between the two groups. Conclusion: The results of this study confirmed that the group computerization cognitive rehabilitation program was more effective in improving cognitive function than the traditional cognitive therapy in patients with cognitive impairment. Based on the results of this study, the group computerization cognitive rehabilitation program can be used as an effective intervention method for patients with cognitive impairment.

• Molecules and Cells
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• v.45 no.10
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• pp.749-760
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• 2022

Osteoclast generation from monocyte/macrophage lineage precursor cells needs to be tightly regulated to maintain bone homeostasis and is frequently over-activated in inflammatory conditions. PARK2, a protein associated with Parkinson's disease, plays an important role in mitophagy via its ubiquitin ligase function. In this study, we investigated whether PARK2 is involved in osteoclastogenesis. PARK2 expression was found to be increased during the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation. PARK2 gene silencing with siRNA significantly reduced osteoclastogenesis induced by RANKL, LPS (lipopolysaccharide), TNFα (tumor necrosis factor α), and IL-1β (interleukin-1β). On the other hand, overexpression of PARK2 promoted osteoclastogenesis. This regulation of osteoclastogenesis by PARK2 was mediated by IKK (inhibitory κB kinase) and NF-κB activation while MAPK (mitogen-activated protein kinases) activation was not involved. Additionally, administration of PARK2 siRNA significantly reduced osteoclastogenesis and bone loss in an in vivo model of inflammatory bone erosion. Taken together, this study establishes a novel role for PARK2 as a positive regulator in osteoclast differentiation and inflammatory bone destruction.

• Journal of Korean Academy of Nursing
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• v.44 no.6
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• pp.697-707
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• 2014

Purpose: The purposes of this study was to develop a comprehensive community-based fall prevention program and to test the effects of the program on the muscle strength, postural balance and fall efficacy for elderly people. Methods: The design of this study was a nonequivalent control group pretest-posttest design. There were 28 participants in the experimental group and 29 in the control group. The program consisted of balance exercises, elastic resistance exercises and prevention education. The program was provided five times a week for 8 weeks and each session lasted 90 minutes. Data were analyzed using ${\chi}^2$-test, independent t-test and paired t-test using the SPSS program. Results: Muscle strength of the lower extremities, postural balance and fall efficacy scores significantly improved in the experimental group compared to the control group. Conclusion: These results suggest that this program can improve lower extremity muscle strength, postural balance and fall efficacy in elders. Therefore, this program is recommended for use in fall prevention programs for elders living in the community.

• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.127-133
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• 2007

Objectives : This study were aimed to estimate the needs for clinical research educational program development focused on oriental medicine. Methods : Department Medical Research of Korea Institute of Oriental Medicine surveyed 204 certified subjects in total by using web-based questionnaires through e-mail from Jan. 17th to Jan. 31th, 2007. Reply from 62 on-line correspondents were collected and statistically analyzed. Results : The number of clinical trial involving oriental medicine continues to increase. According to the survey, many Issues were raised as problems such as difficulty of recruitment, lack of fund and lack of stepped program. Emphasized issues were clinical research methodologies, development of protocols and case report form (CRF), and Regulations including Institutional Review Boards (IRBs) in these three consecutive education training program. Conclusion : The results of this study may contribute to the development of an educational program for oriental medicine, a program that should be taken into consideration for developing practical items, such as, problem-based learnings which reflects participants' actual needs in their works. Also this report be used for future strategy plans and execution of training program for oriental medical clinical trial.